Exposure to p,p'-DDE enhances differentiation of 3T3-L1 preadipocytes in a model of sub-optimal differentiation

Toxicology Letters

Volumn 238, Issue 2, 2015, Pages 65-71

  Mangum, Lauren H ^a   Howell, George E ^a   Chambers, Janice E ^a  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

Author keywords

3T3 L1; Adipogenesis; Organochlorine insecticides; P,p' DDE

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; FATTY ACID BINDING PROTEIN 4; FATTY ACID SYNTHASE; LEPTIN; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; BIOLOGICAL MARKER; FABP4 PROTEIN, HUMAN; FASN PROTEIN, HUMAN; FATTY ACID BINDING PROTEIN; INSECTICIDE; SREBF1 PROTEIN, HUMAN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

3T3 CELL LINE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FATTY ACID SYNTHESIS; FOOD INTAKE; INTRACELLULAR SPACE; LIPID METABOLISM; LIPID STORAGE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; UPREGULATION; ADIPOCYTE; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; TIME;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; BIOMARKERS; DICHLORODIPHENYL DICHLOROETHYLENE; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACID SYNTHASE, TYPE I; FATTY ACID-BINDING PROTEINS; GENE EXPRESSION REGULATION; INSECTICIDES; LEPTIN; MICE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TIME FACTORS; TRIGLYCERIDES;

EID: 84938840389     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.07.009     Document Type: Article

References (33)

1. Arsenijevic T., Grégoire F., Delforge V., Delporte C., Perret J. Murine 3T3-L1 adipocyte cell differentiation model: validated reference genes for qPCR gene expression analysis. PLoS One 2012, 7:e37517.
2. Eckertova M., Ondrejcakova M., Krskova K., Zorad S., Jezova D. Subchronic treatment of rats with oxytocin results in improved adipocyte differentiation and increased gene expression of factors involved in adipogenesis. Br. J. Pharmacol. 2011, 162:452-463.
3. Gerlier D., Thomasset N. Use of MTT colorimetric assay to measure cell activation. J. Immunol. Methods 1986, 94:57-63.
4. Guilherme A., Virbasius J.V., Puri V., Czech M.P. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat. Rev. Mol. Cell Biol. 2008, 9:367-377.
5. Gustafson B. Adipose tissue, inflammation and atherosclerosis. J. Atheroscler. Thromb. 2010, 17:332-341.
6. Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
7. Howell G., Mangum L. Exposure to bioaccumulative organochlorine compounds alters adipogenesis, fatty acid uptake, and adipokine production in NIH3T3-L1 cells. Toxicol. In Vitro 2011, 25:394-402.
8. Ibrahim M.M., Fjaere E., Lock E.J., Naville D., Amlund H., Meugnier E., Le Magueresse Battistoni B., Froyland L., Madsen L., Jessen N., Lund S., Vidal H., Ruzzin J. Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice. PLoS One 2011, 6:e25170.
9. Klimentidis Y.C., Beasley T.M., Lin H.-Y., Murati G., Glass G.E., Guyton M., Newton W., Jorgensen M., Heymsfield S.B., Kemnitz J., Fairbanks L., Allison D.B. Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemics. Proc. R. Soc. B: Biol. Sci. 2010.
10. López-Carrillo L., Torres-Sánchez L., López-Cervantes M., Blair A., Cebrián M.E., Uribe M. The adipose tissue to serum dichlorodiphenyldichloroethane (DDE) ratio: some methodological considerations. Environ. Res. 1999, 81:142-145.
11. Lee D.H., Jacobs D.R., Porta M. Could low-level background exposure to persistent organic pollutants contribute to the social burden of type 2 diabetes?. J. Epidemiol. Commun. Health 2006, 60:1006-1008.
12. Lee D.H., Steffes M.W., Sjodin A., Jones R.S., Needham L.L., Jacobs D.R. Low dose of some persistent organic pollutants predicts type 2 diabetes: a nested case-control study. Environ. Health Perspect. 2010, 118:1235-1242.
13. Lee D.-H., Steffes M.W., Sjödin A., Jones R.S., Needham L.L., Jacobs D.R. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. PLoS One 2011, 6:e15977.
14. Lee D.-H., Lind L., Jacobs Jr D.R., Salihovic S., van Bavel B., Lind P.M. Associations of persistent organic pollutants with abdominal obesity in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study. Environ. Int. 2012, 40:170-178.
15. Li X., Pham H.T., Janesick A.S., Blumberg B. Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ3). Environ. Health Perspect. 2012, 120:1720-1726.
16. Lind P.M., Risérus U., Salihovic S., Bavel B.V., Lind L. An environmental wide association study (EWAS) approach to the metabolic syndrome. Environ. Int. 2013, 55:1-8.
17. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2-δδCT method. Methods 2001, 25:402-408.
18. Longnecker M.P., Daniels J.L. Environmental contaminants as etiologic factors for diabetes. Environ. Health Perspect. 2001, 109:871-876.
19. Lowe C.E., O'Rahilly S., Rochford J.J. Adipogenesis at a glance. J. Cell Sci. 2011, 124:2681-2686.
20. McGinty A., Young I.S. Adipose tissue and inflammation. Int. J. Clin. Pract. 2011, 65:913-917.
21. Moreno-Aliaga M.J., Matsumura F. Effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane (p,p'-DDT) on 3T3-L1 and 3T3-F442A adipocyte differentiation. Biochem. Pharmacol. 2002, 63:997-1007.
22. Ogden C.L., Carroll M.D., Kit B.K., Flegal K.M. Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 2014, 311:806-814.
23. Okwan-Duodu D., Umpierrez G.E., Brawley O.W., Diaz R. Obesity-driven inflammation and cancer risk: role of myeloid derived suppressor cells and alternately activated macrophages. Am. J. Cancer Res. 2013, 3:21.
24. Park Y., Kim Y., Kim J., Yoon K.S., Clark J., Lee J., Park Y. Imidacloprid, a neonicotinoid insecticide, potentiates adipogenesis in 3T3-L1 adipocytes. J. Agric. Food Chem. 2013, 61:255-259.
25. Ruzzin J., Petersen R., Meugnier E., Madsen L., Lock E.J., Lillefosse H., Ma T., Pesenti S., Sonne S.B., Marstrand T.T., Malde M.K., Du Z.Y., Chavey C., Fajas L., Lundebye A.K., Brand C.L., Vidal H., Kristiansen K., Froyland L. Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ. Health Perspect. 2010, 118:465-471.
26. Rylander L., Nilsson-Ehle P., Hagmar L. A simplified precise method for adjusting serum levels of persistent organohalogen pollutants to total serum lipids. Chemosphere 2006, 62:333-336.
27. Schmid B., Rippmann J.F., Tadayyon M., Hamilton B.S. Inhibition of fatty acid synthase prevents preadipocyte differentiation. Biochem. Biophys. Res. Commun. 2005, 328:1073-1082.
28. Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative CT method. Nat. Protoc. 2008, 3:1101.
29. Suganami T., Ogawa Y. Adipose tissue macrophages: their role in adipose tissue remodeling. J. Leukoc. Biol. 2010, 88:33-39.
30. Tung E.W.Y., Boudreau A., Wade M.G., Atlas E. Induction of adipocyte differentiation by polybrominated diphenyl ethers (PBDEs) in 3T3-L1Cells. PLoS One 2014, 9:e94583.
31. Wang C.X., Xu S.Q., Lv Z.Q., Li Y.Y., Wang Y.J., Chen T. Exposure to persistent organic pollutants as potential risk factors for developing diabetes. Sci. Chin. Chem. 2010, 53:980-994.
32. Watanabe M., Inukai K., Katagiri H., Awata T., Oka Y., Katayama S. Regulation of PPARγ transcriptional activity in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 2003, 300:429-436.
33. Yan H., Kermouni A., Abdel-Hafez M., Lau D.C.W. Role of cyclooxygenases COX-1 and COX-2 in modulating adipogenesis in 3T3-L1 cells. J. Lipid Res. 2003, 44:424-429.