Sonic hedgehog stimulates glycolysis and proliferation of breast cancer cells: Modulation of PFKFB3 activation

Biochemical and Biophysical Research Communications

Volumn 464, Issue 3, 2015, Pages 862-868

  Ge, Xin ^a   Lyu, Pengwei ^a   Gu, Yuanting ^a   Li, Lin ^a   Li, Jingruo ^a   Wang, Yan ^a   Zhang, Linfeng ^a   Fu, Chao ^a   Cao, Zhang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

Breast cancer; Glycolysis; p38 MAPK activated kinase; PFKFB3; Proliferation; Sonic hedgehog

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATASE; FRUCTOSE 2,6 BISPHOSPHATE; LACTIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RECOMBINANT PROTEIN; SERINE; SMALL INTERFERING RNA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; G PROTEIN COUPLED RECEPTOR; GLI1 PROTEIN, HUMAN; GLUCOSE; LACTIC ACID DERIVATIVE; MAP-KINASE-ACTIVATED KINASE 2; PFKFB3 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SHH PROTEIN, HUMAN; SIGNAL PEPTIDE; SMO PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER STAGING; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; GLUCOSE UTILIZATION; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; MCF 7 CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR VOLUME; UPREGULATION; BREAST TUMOR; CASE CONTROL STUDY; ENZYME ACTIVATION; FEMALE; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; REFERENCE VALUE; TUMOR CELL LINE;

ERINACEIDAE;

ADULT; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME ACTIVATION; FEMALE; GLUCOSE; GLYCOLYSIS; HEDGEHOG PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LACTATES; MIDDLE AGED; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOFRUCTOKINASE-2; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; REFERENCE VALUES; SERINE; TRANSCRIPTION FACTORS;

EID: 84938746698     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.07.052     Document Type: Article

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