Increased concentrations of fructose 2,6-bisphosphate contribute to the Warburg effect in phosphatase and tensin homolog (PTEN)-deficient cells

Journal of Biological Chemistry

Volumn 288, Issue 50, 2013, Pages 36020-36028

  Cordero Espinoza, Lucía ^a   Hagen, Thilo ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AEROBIC CONDITION; ALLOSTERIC ACTIVATOR; DIFFERENTIATED CELLS; GLYCOLYTIC ENZYME; MOUSE EMBRYONIC FIBROBLASTS; PI3K/AKT SIGNALING; TUMOR SUPPRESSORS; WILD-TYPE LEVELS;

CELL CULTURE; CELL PROLIFERATION; FRUCTOSE; PHOSPHATASES; PROTEINS; TUMORS;

CELLS;

1 PHOSPHOFRUCTOKINASE; APC PROTEIN; ENZYME; FRUCTOSE 2,6 BISPHOSPHATE; LACTIC ACID; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN PFKFB3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME STABILITY; FIBROBLAST; GENETIC TRANSFECTION; GLYCOLYSIS; KNOCKOUT MOUSE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; SYNTHESIS; WARBURG EFFECT; WESTERN BLOTTING; WILD TYPE;

APC/C-CDH1; E3 UBIQUITIN LIGASE; FRUCTOSE 2,6-BISPHOSPHATE; GLYCOLYSIS; PFKFB3; PHOSPHOFRUCTOKINASE; PTEN;

ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; ANIMALS; CDH1 PROTEINS; CELL LINE; FRUCTOSEDIPHOSPHATES; GENE KNOCKOUT TECHNIQUES; GLYCOLYSIS; MICE; PHOSPHOFRUCTOKINASE-2; PROTEOLYSIS; PTEN PHOSPHOHYDROLASE;

EID: 84890383811     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.510289     Document Type: Article

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