Curcumin Reactivates Silenced Tumor Suppressor Gene RARβ by Reducing DNA Methylation

Phytotherapy Research

Volumn 29, Issue 8, 2015, Pages 1237-1245

  Jiang, Apei ^a,b   Wang, Xuemin ^b   Shan, Xiaoyun ^b   Li, Yuan ^b   Wang, Pengqi ^b   Jiang, Pan ^b   Feng, Qing ^b  

^a Zhejiang Chinese Medical School   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

curcumin; DNA methylation; RAR

Indexed keywords

5,6 DIHYDROAZACITIDINE; CURCUMIN; DNA METHYLTRANSFERASE 3B; MESSENGER RNA; RETINOIC ACID RECEPTOR BETA; DNA (CYTOSINE 5) METHYLTRANSFERASE; RETINOIC ACID RECEPTOR;

A549 CELL LINE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CELL LINE; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; DRUG POTENCY; FEMALE; H460 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; LUNG CARCINOGENESIS; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROMOTER REGION; PROTECTION; PROTEIN EXPRESSION; RARBETA GENE; TREATMENT RESPONSE; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; TUMOR CELL LINE;

MUS;

ANIMALS; CELL LINE, TUMOR; CURCUMIN; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HUMANS; MICE; MICE, INBRED BALB C; PROMOTER REGIONS, GENETIC; RECEPTORS, RETINOIC ACID; RNA, MESSENGER; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84938746275     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5373     Document Type: Article

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