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Volumn 16, Issue 12, 2015, Pages 1749-1756

Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein-Sequence Space

(9) Wetzl, Dennis a Berrera, Marco a Sandon, Nicolas a Fishlock, Dan a Ebeling, Martin a Müller, Michael b Hanlon, Steven a Wirz, Beat a Iding, Hans a

a F HOFFMANN LA ROCHE LTD (Switzerland)

b UNIVERSITY OF FREIBURG (Germany)

Author keywords

asymmetric catalysis; biocatalysis; chiral amines; imine reductases; oxidoreductases

Indexed keywords

1 METHYL 1,2,3,4 TETRAHYDROISOQUINOLINE; 1,2,3,4 TETRAHYDROQUINOLINE DERIVATIVE; 2 METHYLPIPERIDINE; BACTERIAL PROTEIN; IMINE; IMINE REDUCTASE; OXIDOREDUCTASE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG; MOLECULAR LIBRARY;

ARTICLE; ASYMMETRIC SYNTHESIS; BIOCATALYST; BIOTRANSFORMATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME PURIFICATION; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; SCREENING; SEQUENCE ALIGNMENT; STREPTOMYCES; STREPTOMYCES TSUKUBAENSIS; STREPTOMYCES VIDIOCHROMOGENES; SUBSTRATE CONCENTRATION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR LIBRARY;

BACTERIA (MICROORGANISMS); STREPTOMYCES; STREPTOMYCES TSUKUBAENSIS;

BACTERIAL PROTEINS; CATALYTIC DOMAIN; IMINES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OXIDOREDUCTASES; SMALL MOLECULE LIBRARIES;

EID: 84938743527 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201500218 Document Type: Article

Times cited : (100)

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