Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus-pituitary-adrenal axis

European Neuropsychopharmacology

Volumn 25, Issue 8, 2015, Pages 1332-1341

  Cai, Li ^a   Li, Rong ^a   Tang, Wen Jian ^a   Meng, Gang ^a   Hu, Xiang Yang ^a   Wu, Ting Ni ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Antidepressant; Chronic unpredictable mild stress (CUMS); Depression; Geniposide; Glucocorticoid receptor (GR ); Hypothalamic pituitary adrenal (HPA) axis

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; FLUOXETINE; GENIPOSIDE; GLUCOCORTICOID RECEPTOR ALPHA; MESSENGER RNA; ANTIDEPRESSANT AGENT; GLUCOCORTICOID RECEPTOR; IRIDOID; SUGAR INTAKE;

ADRENAL GLAND; ADRENAL GLAND INDEX; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHRONIC UNPREDICTABLE STRESS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; DEPRESSION; EXPERIMENTAL HYPERACTIVITY; FORCED SWIM TEST; GENE EXPRESSION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOHISTOCHEMISTRY; MALE; NEGATIVE FEEDBACK; NEUROPHARMACOLOGY; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REARING; RECEPTOR UPREGULATION; SUCROSE PREFERENCE TEST; SUGAR INTAKE; WEIGHT, MASS AND SIZE; ANIMAL; BLOOD; CHRONIC DISEASE; DEPRESSIVE DISORDER; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; FEEDING BEHAVIOR; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MENTAL STRESS; METABOLISM; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; UNCERTAINTY;

ANIMALS; ANTIDEPRESSIVE AGENTS; CHRONIC DISEASE; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DEPRESSIVE DISORDER; DIETARY SUCROSE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDING BEHAVIOR; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IRIDOIDS; MALE; MOTOR ACTIVITY; PITUITARY-ADRENAL SYSTEM; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; STRESS, PSYCHOLOGICAL; UNCERTAINTY;

EID: 84938742338     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2015.04.009     Document Type: Article

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