Inhibition of Myeloid Cell Leukemia 1 and Activation of Caspases Are Critically Involved in Gallotannin-induced Apoptosis in Prostate Cancer Cells

Phytotherapy Research

Volumn 29, Issue 8, 2015, Pages 1225-1236

  Park, Eunkyung ^a   Kwon, Hee Young ^a   Jung, Ji Hoon ^a   Jung, Deok Beom ^a   Jeong, Arong ^a   Cheon, Jinhong ^b   Kim, Bonglee ^a   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

^b Pusan National University   (South Korea)

Author keywords

apoptosis; gallotannin; Mcl 1 overexpression; prostate cancer cells; siRNA Mcl 1

Indexed keywords

CASPASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROCASPASE 3; PROCASPASE 9; PROTEIN MCL 1; SMALL INTERFERING RNA; TANNIN; BCL2 PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE 3; CASPASE 9; MCL1 PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL X;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA 2 EXTRA LARGE GENE; B CELL LYMPHOMA 2 GENE; CANCER CELL; CELL CYCLE G1 PHASE; CELL SUBPOPULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CLEAVAGE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DU145 CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITION; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; M2182 CELL LINE; MALE; MCK 1 GENE; PC 3 CELL LINE; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL GENE; TUNEL ASSAY; DRUG EFFECTS; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

APOPTOSIS; BCL-X PROTEIN; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; HUMANS; HYDROLYZABLE TANNINS; MALE; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; POLY(ADP-RIBOSE) POLYMERASES; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84938741356     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5371     Document Type: Article

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