Effect of gradient steepness on the kinetic performance limits and peak compression for reversed-phase gradient separations of small molecules

Journal of Chromatography A

Volumn 1409, Issue , 2015, Pages 152-158

  Vaňková, Nikola ^a,b   De Vos, Jelle ^b   Tyteca, Eva ^b   Desmet, Gert ^b   Edge, Tony ^c   Česlová, Lenka ^a   Česla, Petr ^a   Eeltink, Sebastiaan ^b  

^a UNIVERSITY OF PARDUBICE   (Czech Republic)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c Thermo Fisher Scientific   (United States)

Author keywords

Accucore; Kinetic plot; Linear solvent strength (LSS) model; Ultra high pressure LC; UPLC

Indexed keywords

KINETICS; MOLECULES; SEPARATION;

ACCUCORE; KINETIC PLOTS; LINEAR SOLVENT STRENGTHS; ULTRA-HIGH-PRESSURE LC; UPLC;

INERTIAL CONFINEMENT FUSION;

PHENOL DERIVATIVE;

ANALYTICAL PARAMETERS; ARTICLE; ELUTION; FLOW RATE; GRADIENT STEEPNESS; ISOCRATIC PERFORMANCE; KINETIC PERFORMANCE LIMIT; LIMIT OF DETECTION; MATHEMATICAL ANALYSIS; PEAK COMPRESSION EFFECT; PRESSURE; PRIORITY JOURNAL; RETENTION FACTOR; REVERSED PHASE GRADIENT SEPARATION; SEPARATION TECHNIQUE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; PROCEDURES;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; KINETICS; PHENOLS; PRESSURE;

EID: 84938739877     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.07.061     Document Type: Article

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