CCDC26, CDKN 2BAS, RTEL1 and TERT Polymorphisms in pediatric brain tumor susceptibility

Carcinogenesis

Volumn 36, Issue 8, 2015, Pages 876-882

  Fahmideh, Maral Adel ^a   Lavebratt, Catharina ^b   Schüz, Joachim ^c   Röösli, Martin ^d,e   Tynes, Tore ^f,g   A Grotzer, Michael ^h   Johansen, Christoffer ^i,j   E Kuehni, Claudia ^k   Lannering, Birgitta ^l   Prochazka, Michaela ^a   S Schmidt, Lisbeth ^m   Feychting, Maria ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^e UNIVERSITY OF BASEL   (Switzerland)

^f CANCER REGISTRY OF NORWAY   (Norway)

^g NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^h UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

ⁱ DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^j UNIVERSITY OF COPENHAGEN   (Denmark)

^k UNIVERSITY OF BERN   (Switzerland)

^l UNIVERSITY OF GOTHENBURG   (Sweden)

^m University of Copenhagen   (Denmark)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CCDC26 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2B; CYCLIN DEPENDENT KINASE INHIBITOR 2BAS; RTEL1 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; CCDC26 PROTEIN, HUMAN; DNA HELICASE; RTEL1 PROTEIN, HUMAN; SIGNAL PEPTIDE; TELOMERASE; TERT PROTEIN, HUMAN;

ADOLESCENT; ADULT; ARTICLE; ASTROCYTOMA; BRAIN TUMOR; CANCER PATIENT; CANCER SUSCEPTIBILITY; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; EPENDYMOMA; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; GLIOBLASTOMA; GLIOMA; HISTOPATHOLOGY; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; MULTICENTER STUDY; PILOCYTIC ASTROCYTOMA; PLEOMORPHIC XANTHOASTROCYTOMA; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SUBEPENDYMOMA; TREND STUDY; TUMOR CLASSIFICATION; YOUNG ADULT; CASE CONTROL STUDY; CLINICAL TRIAL; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; PATHOLOGY;

ADOLESCENT; BRAIN NEOPLASMS; CASE-CONTROL STUDIES; CHILD; DNA HELICASES; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GLIOMA; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; TELOMERASE; YOUNG ADULT;

EID: 84938697583     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv074     Document Type: Article

References (31)

1. Pollack, I.F. et al. (2011) Childhood brain tumors: epidemiology, current management and future directions. Nat. Rev. Neurol., 7, 495-506.
2. Fisher, J.L. et al. (2007) Epidemiology of brain tumors. Neurol. Clin., 25, 867-890.
3. Adel Fahmideh, M. et al. (2014) Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and metaanalysis. Neuro Oncol., 16, 807-814.
4. Rajaraman, P. et al. (2012) Genome-wide association study of glioma and meta-analysis. Hum. Genet., 131, 1877-1888.
5. Sanson, M. et al. (2011) Chromosome 7p11.2 (EGFR) variation influences glioma risk. Hum. Mol. Genet., 20, 2897-2904.
6. Shete, S. et al. (2009) Genome-wide association study identifies five susceptibility loci for glioma. Nat. Genet., 41, 899-904.
7. Wrensch, M. et al. (2009) Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat. Genet., 41, 905-908.
8. Jeon, S. et al. (2013) Genetic variants of AICDA/CASP14 associated with childhood brain tumor. Genet. Mol. Res., 12, 2024-2031.
9. Salnikova, L.E. et al. (2010) Association study of xenobiotic detoxication and repair genes with malignant brain tumors in children. Acta Naturae, 2, 58-65.
10. Searles Nielsen, S. et al. (2010) Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes. Environ. Health Perspect., 118, 144-149.
11. Sirachainan, N. et al. (2008) Folate pathway genetic polymorphisms and susceptibility of central nervous system tumors in Thai children. Cancer Detect. Prev., 32, 72-78.
12. Aydin, D. et al. (2011) Mobile phone use and brain tumors in children and adolescents: a multicenter case-control study. J. Natl Cancer Inst., 103, 1264-1276.
13. Christensen, J.S. et al. (2012) Brain tumors in children and adolescents and exposure to animals and farm life: a multicenter case-control study (CEFALO). Cancer Causes Control, 23, 1463-1473.
14. Steliarova-Foucher, E. et al. (2005) International Classification of Childhood Cancer, third edition. Cancer, 103, 1457-1467.
15. Louis, D.N. et al. (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol., 114, 97-109.
16. Purcell, S, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet., 81, 559-575.
17. Cunnington, M.S. et al. (2010) Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression. PLoS Genet., 6, e1000899.
18. Wapinski, O. et al. (2011) Long noncoding RNAs and human disease. Trends Cell Biol., 21, 354-361.
19. Gu, F. et al. (2013) Common genetic variants in the 9p21 region and their associations with multiple tumours. Br. J. Cancer., 108, 1378-1386.
20. Turnbull, C. et al. (2010) Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet., 42, 504-507.
21. Baird, D.M. (2010) Variation at the TERT locus and predisposition for cancer. Expert Rev. Mol. Med., 12, e16.
22. Barber, L.J. et al. (2008) RTEL1 maintains genomic stability by suppressing homologous recombination. Cell, 135, 261-271.
23. Simon, M. et al. (2010) Genetic risk profiles identify different molecular etiologies for glioma. Clin. Cancer Res., 16, 5252-5259.
24. Jiang, M. et al. (2008) Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim. Biophys. Acta., 1783, 1055-1067.
25. Das, A. et al. (2007) Differentiation decreased telomerase activity in rat glioblastoma C6 cells and increased sensitivity to IFN-gamma and taxol for apoptosis. Neurochem. Res., 32, 2167-2183.
26. Shervington, A. et al. (2006) Glioma: what is the role of c-Myc, hsp90 and telomerase? Mol. Cell. Biochem., 283, 1-9.
27. Tabori, U. et al. (2006) Human telomere reverse transcriptase expression predicts progression and survival in pediatric intracranial ependymoma. J. Clin. Oncol., 24, 1522-1528.
28. Tchirkov, A. et al. (2003) Clinical implications of quantitative realtime RT-PCR analysis of hTERT gene expression in human gliomas. Br. J. Cancer, 88, 516-520.
29. Kim, J.H. et al. (2013) Ependymoma in children: molecular considerations and therapeutic insights. Clin. Transl. Oncol., 15, 759-765.
30. Wong, V.C. et al. (2010) Telomerase inhibition as a novel therapy for pediatric ependymoma. Brain Pathol., 20, 780-786.
31. Rothman, K.J. (1990) No adjustments are needed for multiple comparisons. Epidemiology, 1, 43-46.