Genetic variants of AICDA/CASP14 associated with childhood brain tumor

Genetics and Molecular Research

Volumn 12, Issue 2, 2013, Pages 2024-2031

  Jeon, S ^a   Han, S ^b   Lee, K ^d   Choi, J ^c   Park, S K ^b   Park, A K ^c   Ahn, H S ^b   Shin, H Y ^b   Kang, H J ^b   Koo, H H ^e   Seo, J J ^f   Choi, J E ^g   Kim, H ^b   Ahn, Y ^b   Kang, D ^b,c  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Sunchon National University   (South Korea)

^d Korea National Open University   (South Korea)

^e Sungkyunkwan University School of Medicine   (South Korea)

^f University of Ulsan College of Medicine   (South Korea)

^g Seoul National University Boramae Hospital   (South Korea)

Author keywords

Apoptosis; Cell cycle control; Childhood brain tumor; Single nucleotide polymorphism

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CASPASE 14;

ACTIVATION INDUCED CYTIDINE DEAMINASE GENE; ALGORITHM; APOPTOSIS; ARTICLE; BRAIN TUMOR; CANCER RISK; CASPSAE 14 GENE; CELL CYCLE REGULATION; CHILD; CHILDHOOD CANCER; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GERM CELL TUMOR; GLIOMA; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; PINEAL BODY TUMOR; PRESCHOOL CHILD; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH KOREA; TERATOMA;

APOPTOSIS; BRAIN NEOPLASMS; CASPASES; CELL CYCLE; CHILD; CHILD, PRESCHOOL; CYTIDINE DEAMINASE; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; REPUBLIC OF KOREA; RISK FACTORS;

EID: 84879318704     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2013.January.30.1     Document Type: Article

References (25)

1. Chen BE, Sakoda LC, Hsing AW and Rosenberg PS (2006). Resampling-based multiple hypothesis testing procedures for genetic case-control association studies. Genet. Epidemiol. 30: 495-507.
2. Gangwar R and Mittal RD (2010). Association of selected variants in genes involved in cell cycle and apoptosis with bladder cancer risk in North Indian population. DNA Cell Biol. 29: 349-356.
3. Gu J, Liu Y, Kyritsis AP and Bondy ML (2009). Molecular epidemiology of primary brain tumors. Neurotherapeutics 6: 427-435.
4. Harder T, Plagemann A and Harder A (2008). Birth weight and subsequent risk of childhood primary brain tumors: a meta-analysis. Am. J. Epidemiol. 168: 366-373.
5. Holland EC (2001). Gliomagenesis: genetic alterations and mouse models. Nat. Rev. Genet. 2: 120-129.
6. Honjo T, Nagaoka H, Shinkura R and Muramatsu M (2005). AID to overcome the limitations of genomic information. Nat. Immunol. 6: 655-661.
7. Hsu HC, Yang P, Wu Q, Wang JH, et al. (2011). Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice. Arthritis Rheum. 63: 2038-2048.
8. Koenig U, Sommergruber W and Lippens S (2005). Aberrant expression of caspase-14 in epithelial tumors. Biochem. Biophys. Res. Commun. 335: 309-313.
9. Kohler BA, Ward E, McCarthy BJ, Schymura MJ, et al. (2011). Annual report to the nation on the status of cancer, 1975-2007, featuring tumors of the brain and other nervous system. J. Natl. Cancer Inst. 103: 714-736.
10. Krajewska M, Kim H, Shin E, Kennedy S, et al. (2005). Tumor-associated alterations in caspase-14 expression in epithelial malignancies. Clin. Cancer Res. 11: 5462-5471.
11. Kyritsis AP, Bondy ML, Rao JS and Sioka C (2010). Inherited predisposition to glioma. Neuro-Oncol. 12: 104-113.
12. Lee KM, Ward MH, Han S, Ahn HS, et al. (2009). Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk. Leuk. Res. 33: 250-258.
13. MacGrogan D, Kalakonda N, Alvarez S, Scandura JM, et al. (2004). Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells. Genes Chromosomes Cancer 41: 203-213.
14. Marusawa H (2008). Aberrant AID expression and human cancer development. Int. J. Biochem. Cell Biol. 40: 1399-1402.
15. Maul RW and Gearhart PJ (2010). AID and Somatic Hypermutation. In: Advances in Immunology (Frederick WA, ed.). Vol. 105. Academic Press, New York, 159-191.
16. Ostrom QT and Barnholtz-Sloan JS (2011). Current state of our knowledge on brain tumor epidemiology. Curr. Neurol. Neurosci. Rep. 11: 329-335.
17. Packer BR, Yeager M, Staats B, Welch R, et al. (2004). SNP500Cancer: a public resource for sequence validation and assay development for genetic variation in candidate genes. Nucleic Acids Res. 32: D528-D532.
18. Perez-Duran P, de Yebenes VG and Ramiro AR (2007). Oncogenic events triggered by AID, the adverse effect of antibody diversification. Carcinogenesis 28: 2427-2433.
19. Rajaraman P, Wang SS, Rothman N, Brown MM, et al. (2007). Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults. Cancer Epidemiol. Biomarkers Prev. 16: 1655-1661.
20. Ramiro A, SanMartin BR, McBride K and Jankovic M (2007). The Role of Activation [hyphen (true graphic)] Induced Deaminase in Antibody Diversification and Chromosome Translocations. In: Advances in Immunology (Frederick WA and Tasuku H, eds.). Vol. 94. Academic Press, New York, 75-107.
21. Reddy AT (2001). Advances in biology and treatment of childhood brain tumors. Curr. Neurol. Neurosci. Rep. 1: 137-143.
22. Shim YK, Mlynarek SP and van Wijngaarden E (2009). Parental exposure to pesticides and childhood brain cancer: U.S. Atlantic coast childhood brain cancer study. Environ. Health Perspect. 117: 1002-1006.
23. Wang S, Zhao Y, Ruan Z, Chen H, et al. (2010). Association between EGF +61 G/A and glioma risk in a Chinese population. BMC Cancer 10: 221.
24. Wrensch M, Minn Y, Chew T, Bondy M, et al. (2002). Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro-Oncol. 4: 278-299.
25. Zaheen A, Boulianne B, Parsa JY, Ramachandran S, et al. (2009). AID constrains germinal center size by rendering B cells susceptible to apoptosis. Blood 114: 547-554.