PLGA-Mesoporous Silicon Microspheres for the in Vivo Controlled Temporospatial Delivery of Proteins

ACS Applied Materials and Interfaces

Volumn 7, Issue 30, 2015, Pages 16364-16373

  Minardi, Silvia ^a,b   Pandolfi, Laura ^a,c   Taraballi, Francesca ^a   De Rosa, Enrica ^a   Yazdi, Iman K ^a   Liu, Xeuwu ^a   Ferrari, Mauro ^a   Tasciotti, Ennio ^a  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b INSTITUTE OF SCIENCE AND TECHNOLOGY FOR CERAMICS   (Italy)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

drug delivery; microsphere; PLGA; silicon; tissue engineering

Indexed keywords

BIOCOMPATIBILITY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HISTOLOGY; KINETICS; PROTEINS; SCANNING ELECTRON MICROSCOPY; SILICON; THERMOGRAVIMETRIC ANALYSIS; TISSUE; TISSUE ENGINEERING;

COMPOSITE MICROSPHERES; HISTOLOGICAL EVALUATION; INTRAVITAL MICROSCOPY; MULTI-SCALE COMPOSITES; NANOSTRUCTURED SILICON; PLGA; POLY(DL-LACTIDE-COGLYCOLIDE); REGENERATIVE MEDICINE;

MICROSPHERES;

BOVINE SERUM ALBUMIN; DELAYED RELEASE FORMULATION; LACTIC ACID; MICROCAPSULE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; SILICON DIOXIDE;

ABSORPTION; ADMINISTRATION AND DOSAGE; ANIMAL; CELL LINE; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG EFFECTS; MACROPHAGE; METABOLIC CLEARANCE RATE; METABOLISM; MICROCAPSULE; MOUSE; POROSITY; SYNTHESIS; TISSUE DISTRIBUTION;

ABSORPTION, PHYSICOCHEMICAL; ANIMALS; CAPSULES; CELL LINE; DELAYED-ACTION PREPARATIONS; DIFFUSION; LACTIC ACID; MACROPHAGES; METABOLIC CLEARANCE RATE; MICE; POLYGLYCOLIC ACID; POROSITY; SERUM ALBUMIN, BOVINE; SILICON DIOXIDE; TISSUE DISTRIBUTION;

EID: 84938629696     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.5b03464     Document Type: Article

References (42)

1. Chaudhury, K.; Kumar, V.; Kandasamy, J.; RoyChoudhury, S. Regenerative Nanomedicine: Current Perspectives and Future Directions Int. J. Nanomed. 2014, 9, 4153 10.2147/IJN.S45332
2. Lee, K.; Silva, E. A.; Mooney, D. J. Growth Factor Delivery-Based Tissue Engineering: General Approaches and a Review of Recent Developments J. R. Soc., Interface 2011, 8 (55) 153-170 10.1098/rsif.2010.0223
3. Mantovani, A.; Biswas, S. K.; Galdiero, M. R.; Sica, A.; Locati, M. Macrophage Plasticity and Polarization in Tissue Repair and Remodelling J. Pathol. 2013, 229 (2) 176-185 10.1002/path.4133
4. Law, S.; Chaudhuri, S. Mesenchymal Stem Cell and Regenerative Medicine: Regeneration Versus Immunomodulatory Challenges Am. J. Stem Cells 2013, 2 (1) 22
5. Reya, T.; Morrison, S. J.; Clarke, M. F.; Weissman, I. L. Stem Cells, Cancer, and Cancer Stem Cells Nature 2001, 414 (6859) 105-111 10.1038/35102167
6. Swami, A.; Shi, J.; Gadde, S.; Votruba, A. R.; Kolishetti, N.; Farokhzad, O. C. Nanoparticles for Targeted and Temporally Controlled Drug Delivery. Multifunctional Nanoparticles for Drug Delivery Applications; Springer: New York, 2012; pp 9-29 10.1007/978-1-4614-2305-8.
7. Stroncek, J. D.; Reichert, W. M. Indwelling Neural Implants: Strategies for Contending with the in Vivo Environment; CRC Press: Boca Raton, FL, USA, 2008.
8. Makadia, H. K.; Siegel, S. J. Poly Lactic-Co-Glycolic Acid (Plga) as Biodegradable Controlled Drug Delivery Carrier Polymers 2011, 3 (3) 1377-1397 10.3390/polym3031377
9. Huang, X.; Brazel, C. S. On the Importance and Mechanisms of Burst Release in Matrix-Controlled Drug Delivery Systems J. Controlled Release 2001, 73 (2) 121-136 10.1016/S0168-3659(01)00248-6
10. Vallet-Regí, M.; Balas, F.; Colilla, M.; Manzano, M. Drug Confinement and Delivery in Ceramic Implants Drug Metab Lett. 2007, 1 (1) 37-40 10.2174/187231207779814382
11. Yeo, Y.; Park, K. Control of Encapsulation Efficiency and Initial Burst in Polymeric Microparticle Systems Arch. Pharmacal Res. 2004, 27 (1) 1-12 10.1007/BF02980037
12. Bouissou, C.; Rouse, J.; Price, R.; Van der Walle, C. The Influence of Surfactant on Plga Microsphere Glass Transition and Water Sorption: Remodeling the Surface Morphology to Attenuate the Burst Release Pharm. Res. 2006, 23 (6) 1295-1305 10.1007/s11095-006-0180-2
13. Jain, R. A. The Manufacturing Techniques of Various Drug Loaded Biodegradable Poly (Lactide-< I> Co-Glycolide)(Plga) Devices Biomaterials 2000, 21 (23) 2475-2490 10.1016/S0142-9612(00)00115-0
14. Ruhe, P. Q.; Hedberg, E. L.; Padron, N. T.; Spauwen, P. H.; Jansen, J. A.; Mikos, A. G. Rhbmp-2 Release from Injectable Poly (Dl-Lactic-Co-Glycolic Acid)/Calcium-Phosphate Cement Composites J. Bone Joint Surg. Am. 2003, 85 (suppl-3) 75-81
15. Danhier, F.; Ansorena, E.; Silva, J. M.; Coco, R.; Le Breton, A.; Préat, V. Plga-Based Nanoparticles: An Overview of Biomedical Applications J. Controlled Release 2012, 161 (2) 505-522 10.1016/j.jconrel.2012.01.043
16. Faisant, N.; Akiki, J.; Siepmann, F.; Benoit, J.; Siepmann, J. Effects of the Type of Release Medium on Drug Release from Plga-Based Microparticles: Experiment and Theory Int. J. Pharm. 2006, 314 (2) 189-197 10.1016/j.ijpharm.2005.07.030
17. Xie, S.; Wang, S.; Zhao, B.; Han, C.; Wang, M.; Zhou, W. Effect of Plga as a Polymeric Emulsifier on Preparation of Hydrophilic Protein-Loaded Solid Lipid Nanoparticles Colloids Surf., B 2008, 67 (2) 199-204 10.1016/j.colsurfb.2008.08.018
18. Zhou, J.; Guo, D.; Zhang, Y.; Wu, W.; Ran, H.; Wang, Z. Construction and Evaluation of Fe3o4-Based Plga Nanoparticles Carrying Rtpa Used in the Detection of Thrombosis and in Targeted Thrombolysis ACS Appl. Mater. Interfaces 2014, 6 (8) 5566-5576 10.1021/am406008k
19. Tasciotti, E.; Liu, X.; Bhavane, R.; Plant, K.; Leonard, A. D.; Price, B. K.; Cheng, M. M.-C.; Decuzzi, P.; Tour, J. M.; Robertson, F.; Ferrari, M. Mesoporous Silicon Particles as a Multistage Delivery System for Imaging and Therapeutic Applications Nat. Nanotechnol. 2008, 3 (3) 151-157 10.1038/nnano.2008.34
20. Shen, H.; Rodriguez-Aguayo, C.; Xu, R.; Gonzalez-Villasana, V.; Mai, J.; Huang, Y.; Zhang, G.; Guo, X.; Bai, L.; Qin, G. Enhancing Chemotherapy Response with Sustained Epha2 Silencing Using Multistage Vector Delivery Clin. Cancer Res. 2013, 19 (7) 1806-1815 10.1158/1078-0432.CCR-12-2764
21. Sun, W.; Puzas, J. E.; Sheu, T. J.; Liu, X.; Fauchet, P. M. Nano- to Microscale Porous Silicon as a Cell Interface for Bone-Tissue Engineering Adv. Mater. 2007, 19 (7) 921-924 10.1002/adma.200600319
22. Chiappini, C.; Tasciotti, E.; Fakhoury, J. R.; Fine, D.; Pullan, L.; Wang, Y. C.; Fu, L.; Liu, X.; Ferrari, M. Tailored Porous Silicon Microparticles: Fabrication and Properties ChemPhysChem 2010, 11 (5) 1029-1035 10.1002/cphc.200900914
23. Decuzzi, P.; Godin, B.; Tanaka, T.; Lee, S. Y.; Chiappini, C.; Liu, X.; Ferrari, M. Size and Shape Effects in the Biodistribution of Intravascularly Injected Particles J. Controlled Release 2010, 141 (3) 320-327 10.1016/j.jconrel.2009.10.014
24. Martinez, J. O.; Chiappini, C.; Ziemys, A.; Faust, A. M.; Kojic, M.; Liu, X.; Ferrari, M.; Tasciotti, E. Engineering Multi-Stage Nanovectors for Controlled Degradation And tunable Release Kinetics Biomaterials 2013, 34 (33) 8469-8477 10.1016/j.biomaterials.2013.07.049
25. Fan, D.; De Rosa, E.; Murphy, M. B.; Peng, Y.; Smid, C. A.; Chiappini, C.; Liu, X.; Simmons, P.; Weiner, B. K.; Ferrari, M.; Tasciotti, E. Mesoporous Silicon-Plga Composite Microspheres for the Double Controlled Release of Biomolecules for Orthopedic Tissue Engineering Adv. Funct. Mater. 2012, 22 (2) 282-293 10.1002/adfm.201100403
26. De Rosa, E.; Chiappini, C.; Fan, D.; Liu, X.; Ferrari, M.; Tasciotti, E. Agarose Surface Coating Influences Intracellular Accumulation and Enhances Payload Stability of a Nano-Delivery System Pharm. Res. 2011, 28 (7) 1520-1530 10.1007/s11095-011-0453-2
27. Fan, D.; De Rosa, E.; Murphy, M. B.; Peng, Y.; Smid, C. A.; Chiappini, C.; Liu, X.; Simmons, P.; Weiner, B. K.; Ferrari, M.; Tasciotti, E. Mesoporous Silicon-Plga Composite Microspheres for the Double Controlled Release of Biomolecules for Orthopedic Tissue Engineering Adv. Funct. Mater. 2012, 22 (2) 282-293 10.1002/adfm.201100403
28. De Rosa, E.; Chiappini, C.; Fan, D.; Liu, X.; Ferrari, M.; Tasciotti, E. Agarose Surface Coating Influences Intracellular Accumulation and Enhances Payload Stability of a Nano-Delivery System Pharm. Res. 2011, 28 (7) 1520-1530 10.1007/s11095-011-0453-2
29. Minardi, S.; Sandri, M.; Martinez, J. O.; Yazdi, I. K.; Liu, X.; Ferrari, M.; Weiner, B. K.; Tampieri, A.; Tasciotti, E. Multiscale Patterning of a Biomimetic Scaffold Integrated with Composite Microspheres Small 2014, 10 (19) 3943-3953 10.1002/smll.201401211
30. Taraballi, F.; Minardi, S.; Corradetti, B.; Yazdi, I.; Balliano, M.; Van Eps, J.; Allegri, M.; Tasciotti, E. Potential Avoidance of Adverse Analgesic Effects Using a Biologically" Smart" Hydrogel Capable of Controlled Bupivacaine Release J. Pharm. Sci. 2014, 103 (11) 3724-3732 10.1002/jps.24190
31. Park, K.; Mrsny, R. J. Controlled Drug Delivery: Designing Technologies for the Future, ed. 1; ACS Symposium Series Vol. 752; American Chemical Society: Washington, DC, USA, 2000; p 478.
32. Anderson, J. M.; Shive, M. S. Biodegradation and Biocompatibility of Pla and Plga Microspheres Adv. Drug Delivery Rev. 2012, 64, 72-82 10.1016/j.addr.2012.09.004
33. Spiller, K. L.; Anfang, R. R.; Spiller, K. J.; Ng, J.; Nakazawa, K. R.; Daulton, J. W.; Vunjak-Novakovic, G. The Role of Macrophage Phenotype in Vascularization of Tissue Engineering Scaffolds Biomaterials 2014, 35 (15) 4477-4488 10.1016/j.biomaterials.2014.02.012
34. Taraballi, F.; Minardi, S.; Corradetti, B.; Yazdi, I. K.; Balliano, M. A.; Van Eps, J. L.; Allegri, M.; Tasciotti, E. Potential Avoidance of Adverse Analgesic Effects Using a Biologically "Smart" Hydrogel Capable of Controlled Bupivacaine Release J. Pharm. Sci. 2014, 103 (11) 3724-3732 10.1002/jps.24190
35. Minardi, S.; Sandri, M.; Martinez, J. O.; Yazdi, I. K.; Liu, X.; Ferrari, M.; Weiner, B. K.; Tampieri, A.; Tasciotti, E. Multiscale Patterning of a Biomimetic Scaffold Integrated with Composite Microspheres Small 2014, 10 (19) 3943-3953 10.1002/smll.201401211
36. Tzur-Balter, A.; Shatsberg, Z.; Beckerman, M.; Segal, E.; Artzi, N. Mechanism of Erosion of Nanostructured Porous Silicon Drug Carriers in Neoplastic Tissues Nat. Commun. 2015, 6, 6208 10.1038/ncomms7208
37. Langer, R.; Peppas, N. A. Advances in Biomaterials, Drug Delivery, and Bionanotechnology AIChE J. 2003, 49 (12) 2990-3006 10.1002/aic.690491202
38. Lavan, D. A.; McGuire, T.; Langer, R. Small-Scale Systems for in Vivo Drug Delivery Nat. Biotechnol. 2003, 21 (10) 1184-1191 10.1038/nbt876
39. Epstein, N. E. Complications Due to the Use of Bmp/Infuse in Spine Surgery: The Evidence Continues to Mount Surg. Neurol. Int. 2013, 4 (6 (Suppl 5)) 343 10.4103/2152-7806.114813
40. Epstein, N. E. Pros, Cons, and Costs of Infuse in Spinal Surgery Surg. Neurol. Int. 2011, 2 (1) 10 10.4103/2152-7806.76147
41. Carragee, E. J.; Chu, G.; Rohatgi, R.; Hurwitz, E. L.; Weiner, B. K.; Yoon, S. T.; Comer, G.; Kopjar, B. Cancer Risk after Use of Recombinant Bone Morphogenetic Protein-2 for Spinal Arthrodesis J. Bone Joint Surg. Am. 2013, 95 (17) 1537-1545 10.2106/JBJS.L.01483
42. Anselmo, A. C.; Mitragotri, S. An Overview of Clinical and Commercial Impact of Drug Delivery Systems J. Controlled Release 2014, 190, 15-28 10.1016/j.jconrel.2014.03.053