메뉴 건너뛰기




Volumn 309, Issue 3, 2015, Pages G146-G161

Mitochondrial STAT3 contributes to transformation of barrett’s epithelial cells that express oncogenic ras in a p53-independent fashion

Author keywords

Esophagus; Human; Nuclear; Tumorigenesis; Xenograft

Indexed keywords

PROTEIN P53; SERINE; STAT3 PROTEIN; TYROSINE; PROTEIN P21;

EID: 84938598880     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00462.2014     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 20444446371 scopus 로고    scopus 로고
    • Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors
    • Alvarez JV, Febbo PG, Ramaswamy S, Loda M, Richardson A, Frank DA. Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors. Cancer Res 65: 5054–5062, 2005.
    • (2005) Cancer Res , vol.65 , pp. 5054-5062
    • Alvarez, J.V.1    Febbo, P.G.2    Ramaswamy, S.3    Loda, M.4    Richardson, A.5    Frank, D.A.6
  • 3
    • 64049085356 scopus 로고    scopus 로고
    • Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras
    • Carriere C, Young AL, Gunn JR, Longnecker DS, Korc M. Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras. Biochem Biophys Res Commun 382: 561–565, 2009.
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 561-565
    • Carriere, C.1    Young, A.L.2    Gunn, J.R.3    Longnecker, D.S.4    Korc, M.5
  • 5
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker T, Kovarik P. Serine phosphorylation of STATs. Oncogene 19: 2628–2637, 2000.
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 7
    • 0035914435 scopus 로고    scopus 로고
    • GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:Ubiquinone oxidoreductase (complex I)
    • Fearnley IM, Carroll J, Shannon RJ, Runswick MJ, Walker JE, Hirst J. GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Biol Chem 276: 38345–38348, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 38345-38348
    • Fearnley, I.M.1    Carroll, J.2    Shannon, R.J.3    Runswick, M.J.4    Walker, J.E.5    Hirst, J.6
  • 8
    • 84867057002 scopus 로고    scopus 로고
    • Double trouble: Two cases of squamous carcinoma arising from Barrett’s dysplasia after endoscopic mucosal resection
    • Gorospe EC, Gupta M, Prasad GA, Lewis JT, Wang KK. Double trouble: two cases of squamous carcinoma arising from Barrett’s dysplasia after endoscopic mucosal resection. Am J Gastroenterol 107: 1595–1596, 2012.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1595-1596
    • Gorospe, E.C.1    Gupta, M.2    Prasad, G.A.3    Lewis, J.T.4    Wang, K.K.5
  • 10
    • 84896691813 scopus 로고    scopus 로고
    • The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation
    • Gough DJ, Koetz L, Levy DE. The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation. PloS One 8: e83395, 2013.
    • (2013) Plos One , vol.8
    • Gough, D.J.1    Koetz, L.2    Levy, D.E.3
  • 11
    • 37349098725 scopus 로고    scopus 로고
    • Autocrine IL-6 signaling: A key event in tumorigenesis?
    • Grivennikov S, Karin M. Autocrine IL-6 signaling: a key event in tumorigenesis? Cancer Cell 13: 7–9, 2008.
    • (2008) Cancer Cell , vol.13 , pp. 7-9
    • Grivennikov, S.1    Karin, M.2
  • 12
    • 77955970635 scopus 로고    scopus 로고
    • The prevalence of Barrett’s esophagus in the US: Estimates from a simulation model confirmed by SEER data
    • Hayeck TJ, Kong CY, Spechler SJ, Gazelle GS, Hur C. The prevalence of Barrett’s esophagus in the US: estimates from a simulation model confirmed by SEER data. Dis Esophagus 23: 451–457, 2010.
    • (2010) Dis Esophagus , vol.23 , pp. 451-457
    • Hayeck, T.J.1    Kong, C.Y.2    Spechler, S.J.3    Gazelle, G.S.4    Hur, C.5
  • 13
    • 4544276735 scopus 로고    scopus 로고
    • GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I
    • Huang G, Lu H, Hao A, Ng DC, Ponniah S, Guo K, Lufei C, Zeng Q, Cao X. GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Mol Cell Biol 24: 8447–8456, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 8447-8456
    • Huang, G.1    Lu, H.2    Hao, A.3    Ng, D.C.4    Ponniah, S.5    Guo, K.6    Lufei, C.7    Zeng, Q.8    Cao, X.9
  • 16
    • 0037451235 scopus 로고    scopus 로고
    • GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction
    • Lufei C, Ma J, Huang G, Zhang T, Novotny-Diermayr V, Ong CT, Cao X. GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction. EMBO J 22: 1325–1335, 2003.
    • (2003) EMBO J , vol.22 , pp. 1325-1335
    • Lufei, C.1    Ma, J.2    Huang, G.3    Zhang, T.4    Novotny-Diermayr, V.5    Ong, C.T.6    Cao, X.7
  • 17
    • 84896490633 scopus 로고    scopus 로고
    • Toward a new STATe: The role of STATs in mitochondrial function
    • Meier JA, Larner AC. Toward a new STATe: the role of STATs in mitochondrial function. Semin Immunol 26: 20–28, 2014.
    • (2014) Semin Immunol , vol.26 , pp. 20-28
    • Meier, J.A.1    Larner, A.C.2
  • 18
    • 42449141532 scopus 로고    scopus 로고
    • Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell
    • Mohankumar KM, Perry JK, Kannan N, Kohno K, Gluckman PD, Emerald BS, Lobie PE. Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell. Endocrinology 149: 2219–2229, 2008.
    • (2008) Endocrinology , vol.149 , pp. 2219-2229
    • Mohankumar, K.M.1    Perry, J.K.2    Kannan, N.3    Kohno, K.4    Gluckman, P.D.5    Emerald, B.S.6    Lobie, P.E.7
  • 19
    • 77952029412 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-2 gene disruption promotes Apc(Min/_) tumorigenesis and activator protein-1 activation
    • Newton VA, Ramocki NM, Scull BP, Simmons JG, McNaughton K, Lund PK. Suppressor of cytokine signaling-2 gene disruption promotes Apc(Min/_) tumorigenesis and activator protein-1 activation. Am J Pathol 176: 2320–2332, 2010.
    • (2010) Am J Pathol , vol.176 , pp. 2320-2332
    • Newton, V.A.1    Ramocki, N.M.2    Scull, B.P.3    Simmons, J.G.4    McNaughton, K.5    Lund, P.K.6
  • 20
    • 0026513453 scopus 로고
    • Esophageal squamous carcinoma in five patients with Barrett’s esophagus
    • Paraf F, Flejou JF, Potet F, Molas G, Fekete F. Esophageal squamous carcinoma in five patients with Barrett’s esophagus. Am J Gastroenterol 87: 746–750, 1992.
    • (1992) Am J Gastroenterol , vol.87 , pp. 746-750
    • Paraf, F.1    Flejou, J.F.2    Potet, F.3    Molas, G.4    Fekete, F.5
  • 24
    • 0024486353 scopus 로고
    • Squamous carcinoma of the esophagus in patients with Barrett esophagus
    • Rosengard AM, Hamilton SR. Squamous carcinoma of the esophagus in patients with Barrett esophagus. Mod Pathol 2: 2–7, 1989.
    • (1989) Mod Pathol , vol.2 , pp. 2-7
    • Rosengard, A.M.1    Hamilton, S.R.2
  • 25
    • 84864324029 scopus 로고    scopus 로고
    • GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis
    • Shulga N, Pastorino JG. GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis. J Cell Sci 125: 2995–3003, 2012.
    • (2012) J Cell Sci , vol.125 , pp. 2995-3003
    • Shulga, N.1    Pastorino, J.G.2
  • 26
    • 84881458405 scopus 로고    scopus 로고
    • Barrett esophagus and risk of esophageal cancer: A clinical review
    • Spechler SJ. Barrett esophagus and risk of esophageal cancer: a clinical review. JAMA 310: 627–636, 2013.
    • (2013) JAMA , vol.310 , pp. 627-636
    • Spechler, S.J.1
  • 28
    • 84864315728 scopus 로고    scopus 로고
    • Multi-tasking: Nuclear transcription factors with novel roles in the mitochondria
    • Szczepanek K, Lesnefsky EJ, Larner AC. Multi-tasking: nuclear transcription factors with novel roles in the mitochondria. Trends Cell Biol 22: 429–437, 2012.
    • (2012) Trends Cell Biol , vol.22 , pp. 429-437
    • Szczepanek, K.1    Lesnefsky, E.J.2    Larner, A.C.3
  • 30
    • 84879433956 scopus 로고    scopus 로고
    • Current status and future perspectives on the etiology of esophageal adenocarcinoma
    • Thrift AP, Pandeya N, Whiteman DC. Current status and future perspectives on the etiology of esophageal adenocarcinoma. Front Oncol 2: 11, 2012.
    • (2012) Front Oncol , vol.2 , pp. 11
    • Thrift, A.P.1    Pandeya, N.2    Whiteman, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.