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Volumn 23, Issue 8, 2015, Pages 1368-1379

High Local Concentrations of Intradermal MSCs Restore Skin Integrity and Facilitate Wound Healing in Dystrophic Epidermolysis Bullosa

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 7; ANTIINFLAMMATORY AGENT; COL7A1 PROTEIN, HUMAN;

EID: 84938421986     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2015.58     Document Type: Article
Times cited : (67)

References (54)
  • 2
    • 57649109461 scopus 로고    scopus 로고
    • Clinical research for rare disease: Opportunities, challenges, and solutions
    • Griggs, RC, Batshaw, M, Dunkle, M, Gopal-Srivastava, R, Kaye, E, Krischer, J et al.; Rare Diseases Clinical Research Network. (2009). Clinical research for rare disease: opportunities, challenges, and solutions. Mol Genet Metab 96: 20-26.
    • (2009) Mol Genet Metab , vol.96 , pp. 20-26
    • Griggs, R.C.1    Batshaw, M.2    Dunkle, M.3    Gopal-Srivastava, R.4    Kaye, E.5    Krischer, J.6
  • 6
    • 33750212860 scopus 로고    scopus 로고
    • Molecular basis of inherited skin-blistering disorders, and therapeutic implications
    • Aumailley, M, Has, C, Tunggal, L and Bruckner-Tuderman, L (2006). Molecular basis of inherited skin-blistering disorders, and therapeutic implications. Expert Rev Mol Med 8: 1-21.
    • (2006) Expert Rev Mol Med , vol.8 , pp. 1-21
    • Aumailley, M.1    Has, C.2    Tunggal, L.3    Bruckner-Tuderman, L.4
  • 7
    • 70450235277 scopus 로고    scopus 로고
    • Type VII collagen: The anchoring fbril protein at fault in dystrophic epidermolysis bullosa
    • Chung, HJ and Uitto, J (2010). Type VII collagen: the anchoring fbril protein at fault in dystrophic epidermolysis bullosa. Dermatol Clin 28: 93-105.
    • (2010) Dermatol Clin , vol.28 , pp. 93-105
    • Chung, H.J.1    Uitto, J.2
  • 9
    • 80052975428 scopus 로고    scopus 로고
    • The international dystrophic epidermolysis bullosa patient registry: An online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations
    • van den Akker, PC, Jonkman, MF, Rengaw, T, Bruckner-Tuderman, L, Has, C, Bauer, JW et al. (2011). The international dystrophic epidermolysis bullosa patient registry: an online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations. Hum Mutat 32: 1100-1107.
    • (2011) Hum Mutat , vol.32 , pp. 1100-1107
    • Van Den Akker, P.C.1    Jonkman, M.F.2    Rengaw, T.3    Bruckner-Tuderman, L.4    Has, C.5    Bauer, J.W.6
  • 10
    • 7444248879 scopus 로고    scopus 로고
    • Progress in epidermolysis bullosa: Genetic classifcation and clinical implications
    • Uitto, J and Richard, G (2004). Progress in epidermolysis bullosa: genetic classifcation and clinical implications. Am J Med Genet C Semin Med Genet 131C: 61-74.
    • (2004) Am J Med Genet C Semin Med Genet , vol.131 C , pp. 61-74
    • Uitto, J.1    Richard, G.2
  • 11
    • 77952687069 scopus 로고    scopus 로고
    • Inherited epidermolysis bullosa
    • Fine, JD (2010). Inherited epidermolysis bullosa. Orphanet J Rare Dis 5: 12.
    • (2010) Orphanet J Rare Dis , vol.5 , pp. 12
    • Fine, J.D.1
  • 12
    • 84884396866 scopus 로고    scopus 로고
    • Progress in Epidermolysis bullosa research: Summary of DEBRA International Research Conference 2012
    • Bruckner-Tuderman, L, McGrath, JA, Robinson, EC and Uitto, J (2013). Progress in Epidermolysis bullosa research: summary of DEBRA International Research Conference 2012. J Invest Dermatol 133: 2121-2126.
    • (2013) J Invest Dermatol , vol.133 , pp. 2121-2126
    • Bruckner-Tuderman, L.1    McGrath, J.A.2    Robinson, E.C.3    Uitto, J.4
  • 13
    • 84926016418 scopus 로고    scopus 로고
    • Small-molecule therapies for genetic skin fragility
    • Bruckner-Tuderman, L (2014). Small-molecule therapies for genetic skin fragility. Mol Ther 22: 1724-1725.
    • (2014) Mol Ther , vol.22 , pp. 1724-1725
    • Bruckner-Tuderman, L.1
  • 14
    • 84925937581 scopus 로고    scopus 로고
    • Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: Therapeutic implications for dystrophic epidermolysis bullosa
    • Cogan, J, Weinstein, J, Wang, X, Hou, Y, Martin, S, South, AP et al. (2014). Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa. Mol Ther 22: 1741-1752.
    • (2014) Mol Ther , vol.22 , pp. 1741-1752
    • Cogan, J.1    Weinstein, J.2    Wang, X.3    Hou, Y.4    Martin, S.5    South, A.P.6
  • 15
    • 84887998916 scopus 로고    scopus 로고
    • A phase II randomized vehicle-controlled trial of intradermal allogeneic fbroblasts for recessive dystrophic epidermolysis bullosa
    • Venugopal, SS, Yan, W, Frew, JW, Cohn, HI, Rhodes, LM, Tran, K et al. (2013). A phase II randomized vehicle-controlled trial of intradermal allogeneic fbroblasts for recessive dystrophic epidermolysis bullosa. J Am Acad Dermatol 69: 898-908.e7.
    • (2013) J Am Acad Dermatol , vol.69 , pp. 898-898e7
    • Venugopal, S.S.1    Yan, W.2    Frew, J.W.3    Cohn, H.I.4    Rhodes, L.M.5    Tran, K.6
  • 16
    • 84887040998 scopus 로고    scopus 로고
    • Fibroblast cell therapy enhances initial healing in recessive dystrophic epidermolysis bullosa wounds: Results of a randomized, vehicle-controlled trial
    • Petrof, G, Martinez-Queipo, M, Mellerio, JE, Kemp, P and McGrath, JA (2013). Fibroblast cell therapy enhances initial healing in recessive dystrophic epidermolysis bullosa wounds: results of a randomized, vehicle-controlled trial. Br J Dermatol 169: 1025-1033.
    • (2013) Br J Dermatol , vol.169 , pp. 1025-1033
    • Petrof, G.1    Martinez-Queipo, M.2    Mellerio, J.E.3    Kemp, P.4    McGrath, J.A.5
  • 18
    • 84875016051 scopus 로고    scopus 로고
    • One goal, different strategies-molecular and cellular approaches for the treatment of inherited skin fragility disorders
    • Hünefeld, C, Mezger, M, Kern, JS, Nyström, A, Bruckner-Tuderman, L, Müller, I et al. (2013). One goal, different strategies-molecular and cellular approaches for the treatment of inherited skin fragility disorders. Exp Dermatol 22: 162-167.
    • (2013) Exp Dermatol , vol.22 , pp. 162-167
    • Hünefeld, C.1    Mezger, M.2    Kern, J.S.3    Nyström, A.4    Bruckner-Tuderman Müller L, I.5
  • 19
    • 77950577869 scopus 로고    scopus 로고
    • Replenishment of type VII collagen and re-epithelialization of chronically ulcerated skin after intradermal administration of allogeneic mesenchymal stromal cells in two patients with recessive dystrophic epidermolysis bullosa
    • Conget, P, Rodriguez, F, Kramer, S, Allers, C, Simon, V, Palisson, F et al. (2010). Replenishment of type VII collagen and re-epithelialization of chronically ulcerated skin after intradermal administration of allogeneic mesenchymal stromal cells in two patients with recessive dystrophic epidermolysis bullosa. Cytotherapy 12: 429-431.
    • (2010) Cytotherapy , vol.12 , pp. 429-431
    • Conget, P.1    Rodriguez, F.2    Kramer, S.3    Allers, C.4    Simon, V.5    Palisson, F.6
  • 20
    • 84885099905 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Sensors and switchers of infammation
    • Bernardo, ME and Fibbe, WE (2013). Mesenchymal stromal cells: sensors and switchers of infammation. Cell Stem Cell 13: 392-402.
    • (2013) Cell Stem Cell , vol.13 , pp. 392-402
    • Bernardo, M.E.1    Fibbe, W.E.2
  • 21
    • 58149326737 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production
    • Németh, K, Leelahavanichkul, A, Yuen, PS, Mayer, B, Parmelee, A, Doi, K et al. (2009). Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 15: 42-49.
    • (2009) Nat Med , vol.15 , pp. 42-49
    • Németh, K.1    Leelahavanichkul, A.2    Yuen, P.S.3    Mayer, B.4    Parmelee, A.5    Doi, K.6
  • 22
    • 35348831024 scopus 로고    scopus 로고
    • Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis
    • Wu, Y, Chen, L, Scott, PG and Tredget, EE (2007). Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 25: 2648-2659.
    • (2007) Stem Cells , vol.25 , pp. 2648-2659
    • Wu, Y.1    Chen, L.2    Scott, P.G.3    Tredget, E.E.4
  • 23
    • 42149189474 scopus 로고    scopus 로고
    • Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type
    • Sasaki, M, Abe, R, Fujita, Y, Ando, S, Inokuma, D and Shimizu, H (2008). Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol 180: 2581-2587.
    • (2008) J Immunol , vol.180 , pp. 2581-2587
    • Sasaki, M.1    Abe, R.2    Fujita, Y.3    Ando, S.4    Inokuma, D.5    Shimizu, H.6
  • 24
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-infammatory protein TSG-6
    • Lee, RH, Pulin, AA, Seo, MJ, Kota, DJ, Ylostalo, J, Larson, BL et al. (2009). Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-infammatory protein TSG-6. Cell Stem Cell 5: 54-63.
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3    Kota, D.J.4    Ylostalo, J.5    Larson, B.L.6
  • 25
    • 43049093343 scopus 로고    scopus 로고
    • A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fbroblast therapy
    • Fritsch, A, Loeckermann, S, Kern, JS, Braun, A, Bösl, MR, Bley, TA et al. (2008). A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fbroblast therapy. J Clin Invest 118: 1669-1679.
    • (2008) J Clin Invest , vol.118 , pp. 1669-1679
    • Fritsch, A.1    Loeckermann, S.2    Kern, J.S.3    Braun, A.4    Bösl, M.R.5    Bley, T.A.6
  • 26
    • 69949184884 scopus 로고    scopus 로고
    • Mechanisms of fbroblast cell therapy for dystrophic epidermolysis bullosa: High stability of collagen VII favors long-term skin integrity
    • Kern, JS, Loeckermann, S, Fritsch, A, Hausser, I, Roth, W, Magin, TM et al. (2009). Mechanisms of fbroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity. Mol Ther 17: 1605-1615.
    • (2009) Mol Ther , vol.17 , pp. 1605-1615
    • Kern, J.S.1    Loeckermann, S.2    Fritsch, A.3    Hausser, I.4    Roth, W.5    Magin, T.M.6
  • 29
    • 84892819793 scopus 로고    scopus 로고
    • TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fbrosis in murine full-thickness skin wounds
    • Qi, Y, Jiang, D, Sindrilaru, A, Stegemann, A, Schatz, S, Treiber, N et al. (2014). TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fbrosis in murine full-thickness skin wounds. J Invest Dermatol 134: 526-537.
    • (2014) J Invest Dermatol , vol.134 , pp. 526-537
    • Qi, Y.1    Jiang, D.2    Sindrilaru, A.3    Stegemann, A.4    Schatz, S.5    Treiber, N.6
  • 30
    • 33745356932 scopus 로고    scopus 로고
    • Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling
    • Uemura, R, Xu, M, Ahmad, N and Ashraf, M (2006). Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ Res 98: 1414-1421.
    • (2006) Circ Res , vol.98 , pp. 1414-1421
    • Uemura, R.1    Xu, M.2    Ahmad, N.3    Ashraf, M.4
  • 34
    • 0021802802 scopus 로고
    • Evaluation of anchoring fbrils and other components of the dermal-epidermal junction in dystrophic epidermolysis bullosa by a quantitative ultrastructural technique
    • Tidman, MJ and Eady, RA (1985). Evaluation of anchoring fbrils and other components of the dermal-epidermal junction in dystrophic epidermolysis bullosa by a quantitative ultrastructural technique. J Invest Dermatol 84: 374-377.
    • (1985) J Invest Dermatol , vol.84 , pp. 374-377
    • Tidman, M.J.1    Eady, R.A.2
  • 36
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • Le Blanc, K, Frassoni, F, Ball, L, Locatelli, F, Roelofs, H, Lewis, I et al.; Developmental Committee of the European Group for Blood and Marrow Transplantation. (2008). Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 371: 1579-1586.
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3    Locatelli, F.4    Roelofs Lewis H, I.5
  • 37
    • 33847182092 scopus 로고    scopus 로고
    • Intravenously injected human fbroblasts home to skin wounds, deliver type VII collagen, and promote wound healing
    • Woodley, DT, Remington, J, Huang, Y, Hou, Y, Li, W, Keene, DR et al. (2007). Intravenously injected human fbroblasts home to skin wounds, deliver type VII collagen, and promote wound healing. Mol Ther 15: 628-635.
    • (2007) Mol Ther , vol.15 , pp. 628-635
    • Woodley, D.T.1    Remington, J.2    Huang, Y.3    Hou, Y.4    Li, W.5    Keene, D.R.6
  • 38
    • 84937958474 scopus 로고    scopus 로고
    • Deterministic and stochastic approaches in the clinical application of mesenchymal stromal cells (MSCs)
    • Pacini, S (2014). Deterministic and stochastic approaches in the clinical application of mesenchymal stromal cells (MSCs). Front Cell Dev Biol 2: 50.
    • (2014) Front Cell Dev Biol , vol.2 , pp. 50
    • Pacini, S.1
  • 40
    • 84912141871 scopus 로고    scopus 로고
    • Are clinical trials with mesenchymal stem/progenitor cells too far ahead of the science? Lessons from experimental hematology
    • Prockop, DJ, Prockop, SE and Bertoncello, I (2014). Are clinical trials with mesenchymal stem/progenitor cells too far ahead of the science? Lessons from experimental hematology. Stem Cells 32: 3055-3061.
    • (2014) Stem Cells , vol.32 , pp. 3055-3061
    • Prockop, D.J.1    Prockop, S.E.2    Bertoncello, I.3
  • 41
    • 84926325288 scopus 로고    scopus 로고
    • Immunogenicity of Decidual Stromal Cells in an Epidermolysis Bullosa Patient and in Allogeneic Hematopoietic Stem Cell Transplantation Patients
    • (epub ahead of print)
    • Kaipe, H, Carlson, LM, Erkers, T, Nava, S, Molldén, P, Gustafsson, B et al. (2015). Immunogenicity of Decidual Stromal Cells in an Epidermolysis Bullosa Patient and in Allogeneic Hematopoietic Stem Cell Transplantation Patients. Stem Cells Dev (epub ahead of print).
    • (2015) Stem Cells Dev
    • Kaipe, H.1    Carlson, L.M.2    Erkers, T.3    Nava, S.4    Molldén, P.5    Gustafsson, B.6
  • 42
    • 84855555498 scopus 로고    scopus 로고
    • Focal adhesion kinase links mechanical force to skin fbrosis via infammatory signaling
    • Wong, VW, Rustad, KC, Akaishi, S, Sorkin, M, Glotzbach, JP, Januszyk, M et al. (2012). Focal adhesion kinase links mechanical force to skin fbrosis via infammatory signaling. Nat Med 18: 148-152.
    • (2012) Nat Med , vol.18 , pp. 148-152
    • Wong, V.W.1    Rustad, K.C.2    Akaishi, S.3    Sorkin, M.4    Glotzbach, J.P.5    Januszyk, M.6
  • 43
    • 71949089798 scopus 로고    scopus 로고
    • Forty-two novel COL7A1 mutations and the role of a frequent single nucleotide polymorphism in the MMP1 promoter in modulation of disease severity in a large European dystrophic epidermolysis bullosa cohort
    • Kern, JS, Grüninger, G, Imsak, R, Müller, ML, Schumann, H, Kiritsi, D et al. (2009). Forty-two novel COL7A1 mutations and the role of a frequent single nucleotide polymorphism in the MMP1 promoter in modulation of disease severity in a large European dystrophic epidermolysis bullosa cohort. Br J Dermatol 161: 1089-1097.
    • (2009) Br J Dermatol , vol.161 , pp. 1089-1097
    • Kern, J.S.1    Grüninger, G.2    Imsak, R.3    Müller, M.L.4    Schumann, H.5    Kiritsi, D.6
  • 44
    • 84879845758 scopus 로고    scopus 로고
    • Cutaneous verrucous xanthoma in a bone marrow transplant recipient with recessive dystrophic epidermolysis bullosa
    • Boyd, AS and Roffwarg, D (2013). Cutaneous verrucous xanthoma in a bone marrow transplant recipient with recessive dystrophic epidermolysis bullosa. Pediatr Dermatol 30: 480-483.
    • (2013) Pediatr Dermatol , vol.30 , pp. 480-483
    • Boyd, A.S.1    Roffwarg, D.2
  • 45
    • 60849091919 scopus 로고    scopus 로고
    • Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells
    • Tolar, J, Ishida-Yamamoto, A, Riddle, M, McElmurry, RT, Osborn, M, Xia, L et al. (2009). Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells. Blood 113: 1167-1174.
    • (2009) Blood , vol.113 , pp. 1167-1174
    • Tolar, J.1    Ishida-Yamamoto, A.2    Riddle, M.3    McElmurry, R.T.4    Osborn, M.5    Xia, L.6
  • 46
    • 84927950064 scopus 로고    scopus 로고
    • Preconditioning of mesenchymal stem cells for improved transplantation effcacy in recessive dystrophic epidermolysis bullosa
    • Perdoni, C, McGrath, JA and Tolar, J (2014). Preconditioning of mesenchymal stem cells for improved transplantation effcacy in recessive dystrophic epidermolysis bullosa. Stem Cell Res Ther 5: 121.
    • (2014) Stem Cell Res Ther , vol.5 , pp. 121
    • Perdoni, C.1    McGrath, J.A.2    Tolar, J.3
  • 47
    • 0028856628 scopus 로고
    • Immunohistochemical and mutation analyses demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain
    • Bruckner-Tuderman, L, Nilssen, O, Zimmermann, DR, Dours-Zimmermann, MT, Kalinke, DU, Gedde-Dahl, T Jr et al. (1995). Immunohistochemical and mutation analyses demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain. J Cell Biol 131: 551-559.
    • (1995) J Cell Biol , vol.131 , pp. 551-559
    • Bruckner-Tuderman, L.1    Nilssen, O.2    Zimmermann, D.R.3    Dours-Zimmermann, M.T.4    Kalinke, D.U.5    Gedde-Dahl, T.6
  • 48
    • 36749056828 scopus 로고    scopus 로고
    • Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation
    • Müller, I, Kordowich, S, Holzwarth, C, Isensee, G, Lang, P, Neunhoeffer, F et al. (2008). Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantation. Blood Cells Mol Dis 40: 25-32.
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 25-32
    • Müller, I.1    Kordowich, S.2    Holzwarth, C.3    Isensee, G.4    Lang, P.5    Neunhoeffer, F.6
  • 49
    • 33750195530 scopus 로고    scopus 로고
    • Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM
    • Müller, I, Kordowich, S, Holzwarth, C, Spano, C, Isensee, G, Staiber, A et al. (2006). Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM. Cytotherapy 8: 437-444.
    • (2006) Cytotherapy , vol.8 , pp. 437-444
    • Müller, I.1    Kordowich, S.2    Holzwarth, C.3    Spano, C.4    Isensee, G.5    Staiber, A.6
  • 50
    • 0028839609 scopus 로고
    • High-titer packaging cells producing recombinant retroviruses resistant to human serum
    • Cosset, FL, Takeuchi, Y, Battini, JL, Weiss, RA and Collins, MK (1995). High-titer packaging cells producing recombinant retroviruses resistant to human serum. J Virol 69: 7430-7436.
    • (1995) J Virol , vol.69 , pp. 7430-7436
    • Cosset, F.L.1    Takeuchi, Y.2    Battini, J.L.3    Weiss, R.A.4    Collins, M.K.5
  • 51
    • 0033135776 scopus 로고    scopus 로고
    • High-effciency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fuorescent protein in human marrow stromal cells
    • Marx, JC, Allay, JA, Persons, DA, Nooner, SA, Hargrove, PW, Kelly, PF et al. (1999). High-effciency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fuorescent protein in human marrow stromal cells. Hum Gene Ther 10: 1163-1173.
    • (1999) Hum Gene Ther , vol.10 , pp. 1163-1173
    • Marx, J.C.1    Allay, J.A.2    Persons, D.A.3    Nooner, S.A.4    Hargrove, P.W.5    Kelly, P.F.6
  • 52
    • 78149439868 scopus 로고    scopus 로고
    • Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells
    • Gieseke, F, Böhringer, J, Bussolari, R, Dominici, M, Handgretinger, R and Müller, I (2010). Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells. Blood 116: 3770-3779.
    • (2010) Blood , vol.116 , pp. 3770-3779
    • Gieseke, F.1    Böhringer, J.2    Bussolari, R.3    Dominici, M.4    Handgretinger, R.5    Müller, I.6
  • 53
    • 84878151962 scopus 로고    scopus 로고
    • Rat model for dominant dystrophic epidermolysis bullosa: Glycine substitution reduces collagen VII stability and shows gene-dosage effect
    • Nyström, A, Buttgereit, J, Bader, M, Shmidt, T, Ozcelik, C, Hausser, I et al. (2013). Rat model for dominant dystrophic epidermolysis bullosa: glycine substitution reduces collagen VII stability and shows gene-dosage effect. PLoS One 8: e64243.
    • (2013) PLoS One , vol.8 , pp. e64243
    • Nyström, A.1    Buttgereit, J.2    Bader, M.3    Shmidt, T.4    Ozcelik Hausser C, I.5
  • 54
    • 0028073704 scopus 로고
    • The epitope for anti-type VII collagen monoclonal antibody (LH7:2) locates at the central region of the N-terminal non-collagenous domain of type VII collagen
    • Tanaka, T, Takahashi, K, Furukawa, F and Imamura, S (1994). The epitope for anti-type VII collagen monoclonal antibody (LH7:2) locates at the central region of the N-terminal non-collagenous domain of type VII collagen. Br J Dermatol 131: 472-476.
    • (1994) Br J Dermatol , vol.131 , pp. 472-476
    • Tanaka, T.1    Takahashi, K.2    Furukawa, F.3    Imamura, S.4


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