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Volumn 17, Issue 9, 2009, Pages 1605-1615

Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: High stability of collagen VII favors long-term skin integrity

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 7; EPIDERMAL GROWTH FACTOR;

EID: 69949184884     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.144     Document Type: Article
Times cited : (101)

References (47)
  • 1
    • 43049093343 scopus 로고    scopus 로고
    • A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy
    • Fritsch, A, Loeckermann, S, Kern, JS, Braun, A, Bösl, MR, Bley, TA et al. (2008). A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. J Clin Invest 118: 1669-1679.
    • (2008) J Clin Invest , vol.118 , pp. 1669-1679
    • Fritsch, A.1    Loeckermann, S.2    Kern, J.S.3    Braun, A.4    Bösl, M.R.5    Bley, T.A.6
  • 2
    • 43449084027 scopus 로고    scopus 로고
    • The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB
    • Fine, JD, Eady, RA, Bauer, EA, Bauer, JW, Bruckner-Tuderman, L, Heagerty, A et al. (2008). The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB. J Am Acad Dermatol 58: 931-950.
    • (2008) J Am Acad Dermatol , vol.58 , pp. 931-950
    • Fine, J.D.1    Eady, R.A.2    Bauer, E.A.3    Bauer, J.W.4    Bruckner-Tuderman, L.5    Heagerty, A.6
  • 3
    • 68949125697 scopus 로고    scopus 로고
    • Update on diagnosis and therapy of inherited epidermolysis bullosa
    • Kern, JS and Has, C (2008). Update on diagnosis and therapy of inherited epidermolysis bullosa. Exp Rev Dermatol 3: 721-733.
    • (2008) Exp Rev Dermatol , vol.3 , pp. 721-733
    • Kern, J.S.1    Has, C.2
  • 4
    • 33751161054 scopus 로고    scopus 로고
    • Molecular and diagnostic aspects of genetic skin fragility
    • Has, C and Bruckner-Tuderman, L (2006). Molecular and diagnostic aspects of genetic skin fragility. J Dermatol Sci 44: 129-144.
    • (2006) J Dermatol Sci , vol.44 , pp. 129-144
    • Has, C.1    Bruckner-Tuderman, L.2
  • 5
    • 33750212860 scopus 로고    scopus 로고
    • Molecular basis of inherited skin-blistering disorders, and therapeutic implications
    • Aumailley, M, Has, C, Tunggal, L and Bruckner-Tuderman, L (2006). Molecular basis of inherited skin-blistering disorders, and therapeutic implications. Expert Rev Mol Med 8: 1-21.
    • (2006) Expert Rev Mol Med , vol.8 , pp. 1-21
    • Aumailley, M.1    Has, C.2    Tunggal, L.3    Bruckner-Tuderman, L.4
  • 6
    • 49549111636 scopus 로고    scopus 로고
    • Epidermolysis bullosa: Prospects for cell-based therapies
    • Uitto, J (2008). Epidermolysis bullosa: Prospects for cell-based therapies. J Invest Dermatol 128: 2140-2142.
    • (2008) J Invest Dermatol , vol.128 , pp. 2140-2142
    • Uitto, J.1
  • 7
    • 4344570380 scopus 로고    scopus 로고
    • Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo
    • Woodley, DT, Keene, DR, Atha, T, Huang, Y, Ram, R, Kasahara, N et al. (2004). Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo. Mol Ther 10: 318-326.
    • (2004) Mol Ther , vol.10 , pp. 318-326
    • Woodley, D.T.1    Keene, D.R.2    Atha, T.3    Huang, Y.4    Ram, R.5    Kasahara, N.6
  • 9
    • 0036898193 scopus 로고    scopus 로고
    • Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa
    • Chen, M, Kasahara, N, Keene, DR, Chan, L, Hoeffler, WK, Finlay, D et al. (2002). Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa. Nat Genet 32: 670-675.
    • (2002) Nat Genet , vol.32 , pp. 670-675
    • Chen, M.1    Kasahara, N.2    Keene, D.R.3    Chan, L.4    Hoeffler, W.K.5    Finlay, D.6
  • 10
    • 0037244019 scopus 로고    scopus 로고
    • Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue
    • Ortiz-Urda, S, Lin, Q, Green, CL, Keene, DR, Marinkovich, MP and Khavari, PA (2003). Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. J Clin Invest 111: 251-255.
    • (2003) J Clin Invest , vol.111 , pp. 251-255
    • Ortiz-Urda, S.1    Lin, Q.2    Green, C.L.3    Keene, D.R.4    Marinkovich, M.P.5    Khavari, P.A.6
  • 11
    • 0242658535 scopus 로고    scopus 로고
    • Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone
    • Woodley, DT, Krueger, GG, Jorgensen, CM, Fairley, JA, Atha, T, Huang, Y et al. (2003). Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone. J Invest Dermatol 121: 1021-1028.
    • (2003) J Invest Dermatol , vol.121 , pp. 1021-1028
    • Woodley, D.T.1    Krueger, G.G.2    Jorgensen, C.M.3    Fairley, J.A.4    Atha, T.5    Huang, Y.6
  • 12
    • 33645020760 scopus 로고    scopus 로고
    • Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa
    • Goto, M, Sawamura, D, Ito, K, Abe, M, Nishie, W, Sakai, K et al. (2006). Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa. J Invest Dermatol 126: 766-772.
    • (2006) J Invest Dermatol , vol.126 , pp. 766-772
    • Goto, M.1    Sawamura, D.2    Ito, K.3    Abe, M.4    Nishie, W.5    Sakai, K.6
  • 13
    • 0043133368 scopus 로고    scopus 로고
    • Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors
    • Baldeschi, C, Gache, Y, Rattenholl, A, Bouillé, P, Danos, O, Ortonne, JP et al. (2003). Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors. Hum Mol Genet 12: 1897-1905.
    • (2003) Hum Mol Genet , vol.12 , pp. 1897-1905
    • Baldeschi, C.1    Gache, Y.2    Rattenholl, A.3    Bouillé, P.4    Danos, O.5    Ortonne, J.P.6
  • 15
    • 33845524625 scopus 로고    scopus 로고
    • Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells
    • Mavilio, F, Pellegrini, G, Ferrari, S, Di Nunzio, F, Di Iorio, E, Recchia, A et al. (2006). Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med 12: 1397-1402.
    • (2006) Nat Med , vol.12 , pp. 1397-1402
    • Mavilio, F.1    Pellegrini, G.2    Ferrari, S.3    Di Nunzio, F.4    Di Iorio, E.5    Recchia, A.6
  • 16
    • 51349152151 scopus 로고    scopus 로고
    • Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance
    • Chino, T, Tamai, K, Yamazaki, T, Otsuru, S, Kikuchi, Y, Nimura, K et al. (2008). Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance. Am J Pathol 173: 803-814.
    • (2008) Am J Pathol , vol.173 , pp. 803-814
    • Chino, T.1    Tamai, K.2    Yamazaki, T.3    Otsuru, S.4    Kikuchi, Y.5    Nimura, K.6
  • 17
    • 60849091919 scopus 로고    scopus 로고
    • Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells
    • Tolar, J, Ishida-Yamamoto, A, Riddle, M, McElmurry, RT, Osborn, M, Xia, L et al. (2009). Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells. Blood 113: 1167-1174.
    • (2009) Blood , vol.113 , pp. 1167-1174
    • Tolar, J.1    Ishida-Yamamoto, A.2    Riddle, M.3    McElmurry, R.T.4    Osborn, M.5    Xia, L.6
  • 18
    • 34147139536 scopus 로고    scopus 로고
    • Clinical trials with adult stem/ progenitor cells for tissue repair: Let's not overlook some essential precautions
    • Prockop, DJ and Olson, SD (2007). Clinical trials with adult stem/ progenitor cells for tissue repair: Let's not overlook some essential precautions. Blood 109: 3147-3151.
    • (2007) Blood , vol.109 , pp. 3147-3151
    • Prockop, D.J.1    Olson, S.D.2
  • 19
    • 58149345037 scopus 로고    scopus 로고
    • Epidermolysis bullosa and the risk of life-threatening cancers: The National EB Registry experience, 1986-2006
    • Fine, JD, Johnson, LB, Weiner, M, Li, KP and Suchindran, C (2009). Epidermolysis bullosa and the risk of life-threatening cancers: The National EB Registry experience, 1986-2006. J Am Acad Dermatol 60: 203-211.
    • (2009) J Am Acad Dermatol , vol.60 , pp. 203-211
    • Fine, J.D.1    Johnson, L.B.2    Weiner, M.3    Li, K.P.4    Suchindran, C.5
  • 20
    • 33646128739 scopus 로고    scopus 로고
    • Expanding the COL7A1 mutation database: Novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa
    • Kern, JS, Kohlhase, J, Bruckner-Tuderman, L and Has, C (2006). Expanding the COL7A1 mutation database: Novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa. J Invest Dermatol 126: 1006-1012.
    • (2006) J Invest Dermatol , vol.126 , pp. 1006-1012
    • Kern, J.S.1    Kohlhase, J.2    Bruckner-Tuderman, L.3    Has, C.4
  • 21
    • 0032717715 scopus 로고    scopus 로고
    • Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: A model for recessive dystrophic epidermolysis bullosa
    • Heinonen, S, Männikkö, M, Klement, JF, Whitaker-Menezes, D, Murphy, GF and Uitto, J (1999). Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: A model for recessive dystrophic epidermolysis bullosa. J Cell Sci 112: 3641-3648.
    • (1999) J Cell Sci , vol.112 , pp. 3641-3648
    • Heinonen, S.1    Männikkö, M.2    Klement, J.F.3    Whitaker-Menezes, D.4    Murphy, G.F.5    Uitto, J.6
  • 23
    • 0026600778 scopus 로고
    • Transforming growth factor-beta stimulates collagen VII expression by cutaneous cells in vitro
    • Konig, A and Bruckner-Tuderman, L (1992). Transforming growth factor-beta stimulates collagen VII expression by cutaneous cells in vitro. J Cell Biol 117: 679-685.
    • (1992) J Cell Biol , vol.117 , pp. 679-685
    • Konig, A.1    Bruckner-Tuderman, L.2
  • 25
    • 33847254093 scopus 로고    scopus 로고
    • Novel 3D piezoresistive silicon force sensor for dimensional metrology of micro components
    • Irvine, USA, pp
    • Ruther, P, Bartholomeyczik, W, Dominicus, O, Roth, K, Seitz, W, Strauss, A et al. (2005). Novel 3D piezoresistive silicon force sensor for dimensional metrology of micro components. Proc IEEE Sensors 2005, Irvine, USA, pp. 1006-1009.
    • (2005) Proc IEEE Sensors 2005 , pp. 1006-1009
    • Ruther, P.1    Bartholomeyczik, W.2    Dominicus, O.3    Roth, K.4    Seitz, W.5    Strauss, A.6
  • 26
    • 33847084614 scopus 로고    scopus 로고
    • Formation and function of the myofibroblast during tissue repair
    • Hinz, B (2007). Formation and function of the myofibroblast during tissue repair. J Invest Dermatol 127: 526-537.
    • (2007) J Invest Dermatol , vol.127 , pp. 526-537
    • Hinz, B.1
  • 27
    • 0038236713 scopus 로고    scopus 로고
    • Tenascins: Regulation and putative functions during pathological stress
    • Chiquet-Ehrismann, R and Chiquet, M (2003). Tenascins: Regulation and putative functions during pathological stress. J Pathol 200: 488-499.
    • (2003) J Pathol , vol.200 , pp. 488-499
    • Chiquet-Ehrismann, R.1    Chiquet, M.2
  • 28
    • 33847182092 scopus 로고    scopus 로고
    • Intravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing
    • Woodley, DT, Remington, J, Huang, Y, Hou, Y, Li, W, Keene, DR et al. (2007). Intravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing. Mol Ther 15: 628-635.
    • (2007) Mol Ther , vol.15 , pp. 628-635
    • Woodley, D.T.1    Remington, J.2    Huang, Y.3    Hou, Y.4    Li, W.5    Keene, D.R.6
  • 29
    • 3142713644 scopus 로고    scopus 로고
    • Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa
    • Woodley, DT, Keene, DR, Atha, T, Huang, Y, Lipman, K, Li, W et al. (2004). Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa. Nat Med 10: 693-695.
    • (2004) Nat Med , vol.10 , pp. 693-695
    • Woodley, D.T.1    Keene, D.R.2    Atha, T.3    Huang, Y.4    Lipman, K.5    Li, W.6
  • 30
    • 66549123559 scopus 로고    scopus 로고
    • Bone marrow stem cells improve the survivability of RDEB mice but do not correct the fundamental type VII collagen defect
    • Woodley, D, Wang, X, Zhou, H, Wu, T, Muirhead, T and Chen, M (2008). Bone marrow stem cells improve the survivability of RDEB mice but do not correct the fundamental type VII collagen defect. J Invest Dermatol 128: S126.
    • (2008) J Invest Dermatol , vol.128
    • Woodley, D.1    Wang, X.2    Zhou, H.3    Wu, T.4    Muirhead, T.5    Chen, M.6
  • 31
    • 69949183294 scopus 로고    scopus 로고
    • Bone marrow transplantation restores deficient epidermal basement membrane protein and improves the clinical phenotype in epidermolysis bullosa model mice
    • Fujita, Y, Abe, R, Inokuma, D, Sasaki, M, Hoshina, D, Nishie, W et al. (2008). Bone marrow transplantation restores deficient epidermal basement membrane protein and improves the clinical phenotype in epidermolysis bullosa model mice. J Invest Dermatol 128: S114.
    • (2008) J Invest Dermatol , vol.128
    • Fujita, Y.1    Abe, R.2    Inokuma, D.3    Sasaki, M.4    Hoshina, D.5    Nishie, W.6
  • 32
    • 19944431775 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation and subsequent 80% skin exchange by grafts from the same donor in a patient with Herlitz disease
    • Kopp, J, Horch, RE, Stachel, KD, Holter, W, Kandler, MA, Hertzberg, H et al. (2005). Hematopoietic stem cell transplantation and subsequent 80% skin exchange by grafts from the same donor in a patient with Herlitz disease. Transplantation 79: 255-256.
    • (2005) Transplantation , vol.79 , pp. 255-256
    • Kopp, J.1    Horch, R.E.2    Stachel, K.D.3    Holter, W.4    Kandler, M.A.5    Hertzberg, H.6
  • 33
    • 69949112900 scopus 로고    scopus 로고
    • Adhesive stripping to remove epidermis in junctional epidermolysis bullosa for revertant cell therapy
    • epub ahead of print
    • Gostynski, A, Deviaene, FC, Pasmooij, AM, Pas, HH and Jonkman, MF (2009). Adhesive stripping to remove epidermis in junctional epidermolysis bullosa for revertant cell therapy. Br J Dermatol (epub ahead of print).
    • (2009) Br J Dermatol
    • Gostynski, A.1    Deviaene, F.C.2    Pasmooij, A.M.3    Pas, H.H.4    Jonkman, M.F.5
  • 34
    • 58149250413 scopus 로고    scopus 로고
    • Injection of recombinant human type VII collagen corrects the disease phenotype in a murine model of dystrophic epidermolysis bullosa
    • Remington, J, Wang, X, Hou, Y, Zhou, H, Burnett, J, Muirhead, T et al. (2009). Injection of recombinant human type VII collagen corrects the disease phenotype in a murine model of dystrophic epidermolysis bullosa. Mol Ther 17: 26-33.
    • (2009) Mol Ther , vol.17 , pp. 26-33
    • Remington, J.1    Wang, X.2    Hou, Y.3    Zhou, H.4    Burnett, J.5    Muirhead, T.6
  • 35
    • 58149242428 scopus 로고    scopus 로고
    • Can type VII collagen injections cure dystrophic epidermolysis bullosa?
    • Bruckner-Tuderman, L (2009). Can type VII collagen injections cure dystrophic epidermolysis bullosa? Mol Ther 17: 6-7.
    • (2009) Mol Ther , vol.17 , pp. 6-7
    • Bruckner-Tuderman, L.1
  • 36
    • 69949172122 scopus 로고    scopus 로고
    • Conditional Col7a1 inactivation allows analysis of anchoring fibril stability and function in vivo and reveals a major role of fibroblasts in collagen VII expression
    • Fritsch, A, Kern, JS, Loeckermann, S, Velati, D, Fassler, R and Bruckner-Tuderman, L (2009). Conditional Col7a1 inactivation allows analysis of anchoring fibril stability and function in vivo and reveals a major role of fibroblasts in collagen VII expression. J Invest Dermatol 129: S81.
    • (2009) J Invest Dermatol , vol.129
    • Fritsch, A.1    Kern, J.S.2    Loeckermann, S.3    Velati, D.4    Fassler, R.5    Bruckner-Tuderman, L.6
  • 37
    • 0021802802 scopus 로고
    • Evaluation of anchoring fibrils and other components of the dermal-epidermal junction in dystrophic epidermolysis bullosa by a quantitative ultrastructural technique
    • Tidman, MJ and Eady, RA (1985). Evaluation of anchoring fibrils and other components of the dermal-epidermal junction in dystrophic epidermolysis bullosa by a quantitative ultrastructural technique. J Invest Dermatol 84: 374-377.
    • (1985) J Invest Dermatol , vol.84 , pp. 374-377
    • Tidman, M.J.1    Eady, R.A.2
  • 38
    • 61649100307 scopus 로고    scopus 로고
    • The FGF family: Biology, pathophysiology and therapy
    • Beenken, A and Mohammadi, M (2009). The FGF family: Biology, pathophysiology and therapy. Nat Rev Drug Discov 8: 235-253.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 235-253
    • Beenken, A.1    Mohammadi, M.2
  • 39
    • 0036905115 scopus 로고    scopus 로고
    • Cellular actions of the insulin-like growth factor binding proteins
    • Firth, SM and Baxter, RC (2002). Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23: 824-854.
    • (2002) Endocr Rev , vol.23 , pp. 824-854
    • Firth, S.M.1    Baxter, R.C.2
  • 40
    • 34249804521 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway
    • Martin, JL and Baxter, RC (2007). Expression of insulin-like growth factor binding protein-2 by MCF-7 breast cancer cells is regulated through the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway. Endocrinology 148: 2532-2541.
    • (2007) Endocrinology , vol.148 , pp. 2532-2541
    • Martin, J.L.1    Baxter, R.C.2
  • 41
    • 69449084464 scopus 로고    scopus 로고
    • Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basementmembrane type VII collagen
    • Martins, VL, Vyas, JJ, Chen, M, Purdie, K, Mein, CA, South, AP et al. (2009). Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basementmembrane type VII collagen. J Cell Sci 122: 1788-1799.
    • (2009) J Cell Sci , vol.122 , pp. 1788-1799
    • Martins, V.L.1    Vyas, J.J.2    Chen, M.3    Purdie, K.4    Mein, C.A.5    South, A.P.6
  • 42
    • 53449094862 scopus 로고    scopus 로고
    • Stromal myofibroblasts are drivers of invasive cancer growth
    • De Wever, O, Demetter, P, Mareel, M and Bracke, M (2008). Stromal myofibroblasts are drivers of invasive cancer growth. Int J Cancer 123: 2229-2238.
    • (2008) Int J Cancer , vol.123 , pp. 2229-2238
    • De Wever, O.1    Demetter, P.2    Mareel, M.3    Bracke, M.4
  • 44
    • 0033759279 scopus 로고    scopus 로고
    • Tissue-specific expression and long-term deposition of human collagen VII in the skin of transgenic mice: Implications for gene therapy
    • Sat, E, Leung, KH, Bruckner-Tuderman, L and Cheah, KS (2000). Tissue-specific expression and long-term deposition of human collagen VII in the skin of transgenic mice: Implications for gene therapy. Gene Ther 7: 1631-1639.
    • (2000) Gene Ther , vol.7 , pp. 1631-1639
    • Sat, E.1    Leung, K.H.2    Bruckner-Tuderman, L.3    Cheah, K.S.4
  • 47
    • 0028856628 scopus 로고
    • Immunohistochemical and mutation analyses demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain
    • Bruckner-Tuderman, L, Nilssen, O, Zimmermann, DR, Dours-Zimmermann, MT, Kalinke, DU, Gedde-Dahl, T et al. (1995). Immunohistochemical and mutation analyses demonstrate that procollagen VII is processed to collagen VII through removal of the NC-2 domain. J Cell Biol 131: 551-559.
    • (1995) J Cell Biol , vol.131 , pp. 551-559
    • Bruckner-Tuderman, L.1    Nilssen, O.2    Zimmermann, D.R.3    Dours-Zimmermann, M.T.4    Kalinke, D.U.5    Gedde-Dahl, T.6


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