Big Heart Data: Advancing Health Informatics Through Data Sharing in Cardiovascular Imaging

IEEE Journal of Biomedical and Health Informatics

Volumn 19, Issue 4, 2015, Pages 1283-1290

  Suinesiaputra, Avan ^a   Medrano Gracia, Pau ^a   Cowan, Brett R ^a   Young, Alistair A ^a  

^a THE UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

anatomical models; cardiac atlas; Cardiac MRI; data sharing

Indexed keywords

DATA CURATION; HEART; MEDICAL INFORMATICS;

ANATOMICAL MODELS; CARDIAC ATLAS; CARDIAC MRI; CARDIOVASCULAR FUNCTION; DATA ANALYSIS ALGORITHMS; DISEASE PROGRESSION; EPIDEMIOLOGICAL STUDIES; JOURNAL PUBLISHERS;

DATA SHARING;

BIOLOGICAL MODEL; CARDIAC IMAGING; FACTUAL DATABASE; HUMAN; INFORMATION DISSEMINATION; INTERNET; MEDICAL INFORMATICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES;

CARDIAC IMAGING TECHNIQUES; DATABASES, FACTUAL; HUMANS; INFORMATION DISSEMINATION; INTERNET; MAGNETIC RESONANCE IMAGING; MEDICAL INFORMATICS; MODELS, CARDIOVASCULAR;

EID: 84938394939     PISSN: 21682194     EISSN: 21682208     Source Type: Journal    
DOI: 10.1109/JBHI.2014.2370952     Document Type: Article

References (76)

1. C. J. L. Murray, T. Vos, R. Lozano, M. Naghavi, A. D. Flaxman, C. Michaud, M. Ezzati, K. Shibuya, J.A. Salomon, S. Abdalla,V. Aboyans, J. Abraham, I. Ackerman, R. Aggarwal, S. Y. Ahn, M. K. Ali, M. Alvarado, H. R. Anderson, L. M. Anderson, K. G. Andrews, C. Atkinson, L. M. Baddour,A.N. Bahalim, S. Barker-Collo, L.H. Barrero,D.H. Bartels,M.-G. Basáñez, A. Baxter,M. L. Bell, E. J. Benjamin, D. Bennett, E. Bernabé, K. Bhalla, B. Bhandari, B. Bikbov, A. Bin Abdulhak, G. Birbeck, J. A. Black, H. Blencowe, J. D. Blore, F. Blyth, I. Bolliger, A. Bonaventure, S. Boufous, R. Bourne, M. Boussinesq, T. Braithwaite, C. Brayne, L. Bridgett, S. Brooker, P. Brooks, T. S. Brugha, C. Bryan-Hancock, C. Bucello, R. Buchbinder, G. Buckle, C. M. Budke, M. Burch, P. Burney, R. Burstein, B. Calabria, B. Campbell, C. E. Canter, H. Carabin, J. Carapetis, L. Carmona, C. Cella, F. Charlson, H. Chen, A. T.-A. Cheng, D. Chou, S. S. Chugh, L. E. Coffeng, S. D. Colan, S. Colquhoun, K. E. Colson, J. Condon, M. D. Connor, L. T. Cooper, M. Corriere, M. Cortinovis, K. C. de Vaccaro, W. Couser, B. C. Cowie, M. H. Criqui, M. Cross, K. C. Dabhadkar, M. Dahiya, N. Dahodwala, J. Damsere-Derry, G. Danaei, A. Davis, D. De Leo, L. Degenhardt, R. Dellavalle, A. Delossantos, J. Denenberg, S. Derrett, D. C. Des Jarlais, S. D. Dharmaratne, M. Dherani, C. Diaz-Torne, H. Dolk, E. R. Dorsey, T. Driscoll, H. Duber, B. Ebel, K. Edmond, A. Elbaz, S. E. Ali, H. Erskine, P. J. Erwin, P. Espindola, S. E. Ewoigbokhan, F. Farzadfar, V. Feigin, D. T. Felson, A. Ferrari, C. P. Ferri, E. M. Févre, M. M. Finucane, S. Flaxman, L. Flood, K. Foreman, M. H. Forouzanfar, F. G. R. Fowkes, M. Fransen, M. K. Freeman, B. J. Gabbe, S. E. Gabriel, E. Gakidou, H. A. Ganatra, B. Garcia, F. Gaspari, R. F. Gillum, G. Gmel, D. Gonzalez-Medina, R. Gosselin, R. Grainger, B. Grant, J. Groeger, F. Guillemin, D. Gunnell, R. Gupta, J. Haagsma, H. Hagan, Y. A. Halasa, W. Hall, D. Haring, J. M. Haro, J. E. Harrison, R. Havmoeller, R. J. Hay, H. Higashi, C. Hill, B. Hoen, H. Hoffman, P. J. Hotez, D. Hoy, J. J. Huang, S. E. Ibeanusi, K. H. Jacobsen, S. L. James, D. Jarvis, R. Jasrasaria, S. Jayaraman, N. Johns, J. B. Jonas, G. Karthikeyan, N. Kassebaum, N. Kawakami, A. Keren, J.-P. Khoo, C. H. King, L. M. Knowlton, O. Kobusingye, A. Koranteng, R. Krishnamurthi, F. Laden, R. Lalloo, L. L. Laslett, T. Lathlean, J. L. Leasher, Y. Y. Lee, J. Leigh, D. Levinson, S. S. Lim, E. Limb, J. K. Lin, M. Lipnick, S. E. Lipshultz, W. Liu, M. Loane, S. L. Ohno, R. Lyons, J. Mabweijano, M. F. MacIntyre, R. Malekzadeh, L.Mallinger, S. Manivannan,W. Marcenes, L.March, D. J. Margolis, G. B. Marks, R. Marks, A. Matsumori, R. Matzopoulos, B. M. Mayosi, J. H. McAnulty, M. M. McDermott, N. McGill, J. McGrath, M. E. Medina-Mora, M. Meltzer, G. A. Mensah, T. R. Merriman, A.-C. Meyer, V. Miglioli, M. Miller, T. R. Miller, P. B. Mitchell, C. Mock, A. O. Mocumbi, T. E. Moffitt, A. A. Mokdad, L. Monasta, M. Montico, M. Moradi-Lakeh, A. Moran, L. Morawska, R. Mori, M. E. Murdoch, M. K. Mwaniki, K. Naidoo, M. N. Nair, L. Naldi, K. M. V. Narayan, P. K. Nelson, R. G. Nelson, M. C. Nevitt, C. R. Newton, S. Nolte, P. Norman, R. Norman, M. O.Donnell, S. O.Hanlon, C. Olives, S. B. Omer, K. Ortblad, R. Osborne, D. Ozgediz, A. Page, B. Pahari, J. D. Pandian, A. P. Rivero, S. B. Patten, N. Pearce, R. P. Padilla, F. Perez-Ruiz, N. Perico, K. Pesudovs, D. Phillips, M. R. Phillips, K. Pierce, S. Pion, G.V. Polanczyk, S. Polinder, C. A. Pope, 3rd, S. Popova, E. Porrini, F. Pourmalek, M. Prince, R. L. Pullan, K. D. Ramaiah, D. Ranganathan, H. Razavi, M. Regan, J. T. Rehm, D. B. Rein, G. Remuzzi, K. Richardson, F. P. Rivara, T. Roberts, C. Robinson, F.R.DeLeón, L. Ronfani, R. Room, L.C.Rosenfeld, L.Rushton, R. L. Sacco, S. Saha, U. Sampson, L. Sanchez-Riera, E. Sanman, D. C. Schwebel, J. G. Scott, M. Segui-Gomez, S. Shahraz, D. S. Shepard, H. Shin, R. Shivakoti, D. Singh, G. M. Singh, J. A. Singh, J. Singleton, D. A. Sleet, K. Sliwa, E. Smith, J. L. Smith, N. J. C. Stapelberg, A. Steer, T. Steiner, W. A. Stolk, L. J. Stovner, C. Sudfeld, S. Syed, G. Tamburlini, M. Tavakkoli, H. R. Taylor, J. A. Taylor, W. J. Taylor, B. Thomas, W. M. Thomson, G. D. Thurston, I. M. Tleyjeh, M. Tonelli, J. A. Towbin, T. Truelsen, M. K. Tsilimbaris, C. Ubeda, E. A. Undurraga, M. J. van der Werf, J. van Os, M. S. Vavilala, N. Venketasubramanian, M. Wang, W. Wang, K. Watt, D. J. Weatherall, M. A. Weinstock, R. Weintraub, M. G. Weisskopf, M. M. Weissman, R. A. White, H. Whiteford, N. Wiebe, S. T. Wiersma, J. D. Wilkinson, H. C. Williams, S. R. M. Williams, E. Witt, F. Wolfe, A. D. Woolf, S. Wulf, P.-H. Yeh, A. K. M. Zaidi, Z.-J. Zheng, D. Zonies, A. D. Lopez, M. A. AlMazroa, and Z. A. Memish, "Disabilityadjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: A systematic analysis for the global burden of disease study 2010," Lancet, vol. 380, no. 9859, pp. 2197-223, Dec. 2012.
2. "Health loss in New Zealand: A report from the New Zealand burden of diseases, injuries and risk factors study, 2006-2016," Ministry Health, Wellington, New Zealand, Tech. Rep. 5687, 2013.
3. I. S. Kohane, "The twin questions of personalized medicine: Who are you and whom do you most resemble?," Genome Med., vol. 1, no. 1, p. 4, 2009.
4. T. P. Sneddon, P. Li, and S. C. Edmunds, "GigaDB: Announcing the gigascience database," Gigascience, vol. 1, no. 1, p. 11, 2012.
5. S. Mori, K. Oishi, A. V. Faria, and M. I. Miller, "Atlas-based neuroinformatics via MRI: Harnessing information from past clinical cases and quantitative image analysis for patient care," Annu. Rev. Biomed. Eng., vol. 15, pp. 71-92, 2013.
6. C. G. Fonseca, M. Backhaus, D. A. Bluemke, R. D. Britten, J. D. Chung, B. R. Cowan, I. D. Dinov, J. P. Finn, P. J. Hunter, A. H. Kadish, D. C. Lee, J. A. C. Lima, P. Medrano-Gracia, K. Shivkumar, A. Suinesiaputra, W. Tao, and A. A. Young, "The cardiac atlas project - An imaging database for computational modeling and statistical atlases of the heart," Bioinformatics, vol. 27, no. 16, pp. 2288-2295, Aug. 2011.
7. W. B. Kannel, T. R. Dawber, A. Kagan, N. Revotskie, and J. Stokes, III, "Factors of risk in the development of coronary heart disease - Six year follow-up experience. The Framingham study," Ann. Intern. Med., vol. 55, pp. 33-50, Jul. 1961.
8. T. B. Murdoch and A. S. Detsky, "The inevitable application of big data to health care," J. Amer. Med. Assoc., vol. 309, no. 13, pp. 1351-1352, Apr. 2013.
9. S. E. Petersen, P. M. Matthews, F. Bamberg, D. A. Bluemke, J. M. Francis, M. G. Friedrich, P. Leeson, E. Nagel, S. Plein, F. E. Rademakers, A. A. Young, S. Garratt, T. Peakman, J. Sellors, R. Collins, and S. Neubauer, "Imaging in population science: Cardiovascular magnetic resonance in 100,000 participants of UK biobank - Rationale, challenges and approaches," J. Cardiovasc. Magn. Reson., vol. 15, p. 46, 2013.
10. N. D. Wong, "Epidemiological studies of CHD and the evolution of preventive cardiology," Nat. Rev. Cardiol., vol. 11, no. 5, pp. 276-89, May. 2014.
11. D. E. Bild, D. A. Bluemke, G. L. Burke, R. Detrano, A. V. Diez Roux, A. R. Folsom, P. Greenland, D. R. Jacob, Jr, R. Kronmal, K. Liu, J. C. Nelson, D. O'Leary, M. F. Saad, S. Shea, M. Szklo, and R. P. Tracy, "Multi-ethnic study of atherosclerosis: Objectives and design," Amer. J. Epidemiol., vol. 156, no. 9, pp. 871-81, Nov. 2002.
12. H. A. Taylor, Jr., J. G. Wilson, D. W. Jones, D. F. Sarpong, A. Srinivasan, R. J. Garrison, C. Nelson, and S. B. Wyatt, "Toward resolution of cardiovascular health disparities in African Americans: Design and methods of the Jackson heart study," Ethn. Dis., vol. 15, no. 4, pp. S6-4-S6-17, 2005.
13. M. J. Borugian, P. Robson, I. Fortier, L. Parker, J. McLaughlin, B. M. Knoppers, K. Be .dard, R. P. Gallagher, S. Sinclair, V. Ferretti, H. Whelan, D. Hoskin, and J. D. Potter, "The Canadian partnership for tomorrow project: Building a pan-Canadian research platform for disease prevention," Can. Med. Assoc. J., vol. 182, no. 11, pp. 1197-1201, Aug. 2010.
14. E. B. Schelbert, J. J. Cao, S. Sigurdsson, T. Aspelund, P. Kellman, A. H. Aletras, C. K. Dyke, G. Thorgeirsson, G. Eiriksdottir, L. J. Launer, V. Gudnason, T. B. Harris, and A. E. Arai, "Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults," J. Amer. Med. Assoc., vol. 308, no. 9, pp. 890-896, Sep. 2012.
15. M. L. Chuang, P. Gona, G. L. T. F. Hautvast, C. J. Salton, M. Breeuwer, C. J. O..Donnell, and W. J. Manning, "CMR reference values for left ventricular volumes, mass, and ejection fraction using computer-aided analysis: The Framingham heart study," J. Magn. Reson. Imag., vol. 39, no. 4, pp. 895-900, Apr. 2014.
16. O. Bruder, A. Wagner, M. Lombardi, J. Schwitter, A. van Rossum, G. Pilz, D. Nothnagel, H. Steen, S. Petersen, E. Nagel, S. Prasad, J. Schumm, S. Greulich, A. Cagnolo, P. Monney, C. C. Deluigi, T. Dill, H. Frank, G. Sabin, S. Schneider, and H. Mahrholdt, "European cardiovascular magnetic resonance (EuroCMR) registry - Multi national results from 57 centers in 15 countries," J. Cardiovasc. Magn. Reson., vol. 15, art. no. 9, 2013.
17. D. E. Bild, R. McClelland, J. D. Kaufman, R. Blumenthal, G. L. Burke, J. J. Carr,W. S. Post, T. C. Register, S. Shea, andM. Szklo, "Ten-year trends in coronary calcification in individuals without clinical cardiovascular disease in the multi-ethnic study of atherosclerosis," PLoS One, vol. 9, no. 4, p. e94916, 2014.
18. D. A. Bluemke, R. A. Kronmal, J. A. C. Lima, K. Liu, J. Olson, G. L. Burke, and A. R. Folsom, "The relationship of left ventricular mass and geometry to incident cardiovascular events: The MESA (multi-ethnic study of atherosclerosis) study," J. Amer. Coll. Cardiol., vol. 52, no. 25, pp. 2148-2155, Dec. 2008.
19. J. Harman, E. R. Walker, V. Charbonneau, E. L. Akylbekova, C. Nelson, and S. B. Wyatt, "Treatment of hypertension among african americans: The jackson heart study," J. Clin. Hypertens. (Greenwich), vol. 15, no. 6, pp. 367-374, Jun. 2013.
20. H. A. Taylor, Jr., "The Jackson heart study: An overview," Ethn. Dis., vol. 15, no. 4 pp. S6-1-S6-3, 2005.
21. T. J. Payne, S. B. Wyatt, T. H. Mosley, P. M. Dubbert, M. L. Guiterrez-Mohammed, R. L. Calvin, H. A. Taylor, Jr, and D. R. Williams, "Sociocultural methods in the Jackson heart study: Conceptual and descriptive overview," Ethn. Dis., vol. 15, no. 4, pp. S6-38-S6-48, 2005.
22. C. R. Clark, M. J. Ommerborn, D. A. Hickson et al., "Neighborhood disadvantage, neighborhood safety and cardiometabolic risk factors in African Americans: Biosocial associations in the Jackson heart study," PLoS One, vol. 8, no. 5, p. e63254, 2013.
23. J. J. Carr, "The revolution in risk assessment and disease detection made possible with non-invasive imaging: Implications for population science," Ethn. Dis., vol. 22, no. 3, pp. S1-24-S1-7, 2012.
24. A. E. Flanders, "Medical image and data sharing: Are we there yet?," Radiographics, vol. 29, no. 5, pp. 1247-1251, 2009.
25. M. Li, D. Carrell, J. Aberdeen, L. Hirschman, and B. A. Malin, "Deidentification of clinical narratives through writing complexity measures," Int. J. Med. Inform., vol. 83, no. 10, pp. 750-767, Oct. 2014.
26. A. Gkoulalas-Divanis, G. Loukides, and J. Sun, "Publishing data from electronic health records while preserving privacy: A survey of algorithms," J. Biomed. Inform., vol. 50, pp. 4-19, Aug. 2014.
27. A. Suinesiaputra, B. R. Cowan,A.O.Al-Agamy, M. A. Elattar,N.Ayache, A. S. Fahmy, A. M. Khalifa, P. Medrano-Gracia, M.-P. Jolly, A. H. Kadish, D. C. Lee, J. Margeta, S. K. Warfield, and A. A. Young, "A collaborative resource to build consensus for automated left ventricular segmentation of cardiac MR images," Med. Image Anal., vol. 18, no. 1, pp. 50-62, Jan. 2014.
28. A. H. Kadish, D. Bello, J. P. Finn, R. O. Bonow, A. Schaechter, H. Subacius, C. Albert, J. P. Daubert, C. G. Fonseca, and J. J. Goldberger, "Rationale and design for the defibrillators to reduce risk by magnetic resonance imaging evaluation (DETERMINE) trial," J. Cardiovasc. Electrophysiol., vol. 20, no. 9, pp. 982-987, Sep. 2009.
29. Y. Ge, D. K. Ahn, B. Unde, H. D. Gage, and J. J. Carr, "Patientcontrolled sharing of medical imaging data across unaffiliated healthcare organizations," J. Amer. Med. Inform. Assoc., vol. 20, no. 1, pp. 157-63, Jan. 2013.
30. D. Gianni, S. McKeever, T. Yu, R. Britten, H. Delingette, A. Frangi, P. Hunter, and N. Smith, "Sharing and reusing cardiovascular anatomical models over the web: A step towards the implementation of the virtual physiological human project," Philos. Trans. Math. Phys. Eng. Sci., vol. 368, no. 1921, pp. 3039-3056, Jun. 2010.
31. E. Kerfoot, P. Lamata, S. Niederer, R. Hose, J. Spaan, and N. Smith, "Share and enjoy: Anatomical models database-generating and sharing cardiovascular model data using web services," Med. Biol. Eng. Comput., vol. 51, no. 11, pp. 1181-1190, Nov. 2013.
32. P. Medrano-Gracia, B. R. Cowan, D. A. Bluemke et al., "Atlas-based analysis of cardiac shape and function: Correction of regional shape bias due to imaging protocol for population studies," J. Cardiovasc. Magn. Reson., vol. 15, art. no. 80, 2013.
33. Society of Cardiovascular Magnetic Resonance. [Online]. Available: http://www.scmr.org/Research/cap-dicom-transfer.html
34. N. Smith, A. de Vecchi, M. McCormick, D. Nordsletten, O. Camara, A. F. Frangi, H. Delingette, M. Sermesant, J. Relan, N. Ayache, M.W. Krueger, W. H.W. Schulze, R. Hose, I.Valverde, P. Beerbaum, C. Staicu,M. Siebes, J. Spaan, P. Hunter, J. Weese, H. Lehmann, D. Chapelle, and R. Rezavi, "Euheart: Personalized and integrated cardiac care using patient-specific cardiovascular modelling," Interface Focus, vol. 1, no. 3, pp. 349-364, Jun. 2011.
35. P. Lamata, S. Niederer, D. Nordsletten, D. C. Barber, I. Roy, D. R. Hose, and N. Smith, "An accurate, fast and robust method to generate patientspecific cubic hermite meshes," Med. Image Anal., vol. 15, no. 6, pp. 801-813, Dec. 2011.
36. L. Ohno-Machado, V. Bafna, A. A. Boxwala, B. E. Chapman, W. W. Chapman, K. Chaudhuri, M. E. Day, C. Farcas, N. D. Heintzman, X. Jiang, H. Kim, J. Kim, M. E. Matheny, F. S. Resnic, S. A. Vinterbo, and iDASH team, "iDASH: Integrating data for analysis, anonymization, and sharing," J. Amer. Med. Inform. Assoc., vol. 19, no. 2, pp. 196-201, 2012.
37. A. L. Goldberger, L. A. Amaral, L. Glass, J. M. Hausdorff, P. C. Ivanov, R. G. Mark, J. E. Mietus, G. B. Moody, C. K. Peng, and H. E. Stanley, "Physiobank, physiotoolkit, and physionet: Components of a newresearch resource for complex physiologic signals," Circulation, vol. 101, no. 23, pp. E215-E220, Jun. 2000.
38. S. Steinert-Threlkeld, S. Ardekani, J. L. V. Mejino, L. T. Detwiler, J. F. Brinkley, M. Halle, R. Kikinis, R. L. Winslow, M. I. Miller, and J. T. Ratnanather, "Ontological labels for automated location of anatomical shape differences," J. Biomed. Inform., vol. 45, no. 3, pp. 522-527, Jun. 2012.
39. T. Glatard, C. Lartizien, B. Gibaud, R. F. da Silva, G. Forestier, F. Cervenansky, M. Alessandrini, H. Benoit-Cattin, O. Bernard, S. Camarasu-Pop, N. Cerezo, P. Clarysse, A. Gaignard, P. Hugonnard, H. Liebgott, S. Marache, A. Marion, J. Montagnat, J. Tabary, and D. Friboulet, "A virtual imaging platform for multi-modality medical image simulation," IEEE Trans. Med. Imag., vol. 32, no. 1, pp. 110-118, Jan. 2013.
40. M. A.Konstam,D.G.Kramer, A. R. Patel, M. S. Maron, and J. E.Udelson, "Left ventricular remodeling in heart failure: Current concepts in clinical significance and assessment," JACC Cardiovasc. Imag., vol. 4, no. 1, pp. 98-108, Jan. 2011.
41. M. G. Sutton and N. Sharpe, "Left ventricular remodeling after myocardial infarction: Pathophysiology and therapy," Circulation, vol. 101, no. 25, pp. 2981-2988, Jun. 2000.
42. J. N. Cohn, R. Ferrari, and N. Sharpe, "Cardiac remodeling - Concepts and clinical implications: A consensus paper from an international forum on cardiac remodeling. Behalf of an international forum on cardiac remodeling," J. Amer. Coll. Cardiol., vol. 35, no. 3, pp. 569-582, Mar. 2000.
43. J. S. Burchfield, M. Xie, and J. A. Hill, "Pathological ventricular remodeling: Mechanisms: Part 1 of 2," Circulation, vol. 128, no. 4, pp. 388-400, Jul. 2013.
44. G. F. Mitchell, G. A. Lamas, D. E. Vaughan, and M. A. Pfeffer, "Left ventricular remodeling in the year after first anteriormyocardial infarction: A quantitative analysis of contractile segment lengths and ventricular shape," J. Amer. Coll. Cardiol., vol. 19, no. 6, pp. 1136-1144, May. 1992.
45. S. P. Wong, J. K. French, A.-M. Lydon, S. O. M. Manda, W. Gao, N. G. Ashton, and H. D. White, "Relation of left ventricular sphericity to 10-year survival after acute myocardial infarction," Amer. J. Cardiol., vol. 94, no. 10, pp. 1270-1275, Nov. 2004.
46. H. F. J. Mannaerts, J. A. van der Heide, O. Kamp, M. G. Stoel, J. Twisk, and C. A. Visser, "Early identification of left ventricular remodelling after myocardial infarction, assessed by transthoracic 3D echocardiography," Eur. Heart J., vol. 25, no. 8, pp. 680-687, Apr. 2004.
47. R. S. Vasan, M. G. Larson, E. J. Benjamin, J. C. Evans, and D. Levy, "Left ventricular dilatation and the risk of congestive heart failure in peoplewithout myocardial infarction," New Engl. J.Med., vol. 336, no. 19, pp. 1350-1355, May. 1997.
48. M. S. Lauer, J. C. Evans, and D. Levy, "Prognostic implications of subclinical left ventricular dilatation and systolic dysfunction in men free of overt cardiovascular disease (the Framingham heart study)," Amer. J. Cardiol., vol. 70, no. 13, pp. 1180-1184, Nov. 1992.
49. W. B. Kannel, D. Levy, and L. A. Cupples, "Left ventricular hypertrophy and risk of cardiac failure: Insights from the Framingham study," J. Cardiovasc. Pharmacol., vol. 10, pp. S135-S140, 1987.
50. M. A. Konstam, J. E. Udelson, and N. Sharpe, "Prevention and reversal of left ventricular remodeling: Summation," J. Cardiac Failure, vol. 8, no. 6, pp. S506-S511, Dec. 2002.
51. N. Duchateau, M. De Craene, G. Piella, E. Silva, A. Doltra, M. Sitges, B. H. Bijnens, and A. F. Frangi, "A spatiotemporal statistical atlas of motion for the quantification of abnormal myocardial tissue velocities," Med. Image Anal., vol. 15, no. 3, pp. 316-328, Jun. 2011.
52. C. Hoogendoorn, N. Duchateau, D. Sánchez-Quintana, T. Whitmarsh, F. M. Sukno, M. De Craene, K. Lekadir, and A. F. Frangi, "A high-resolution atlas and statistical model of the human heart from multislice CT," IEEE Trans. Med. Imag., vol. 32, no. 1, pp. 28-44, Jan. 2013.
53. A. J. Lewandowski, D. Augustine, P. Lamata, E. F. Davis, M. Lazdam, J. Francis, K. McCormick, A. R. Wilkinson, A. Singhal, A. Lucas, N. P. Smith, S. Neubauer, and P. Leeson, "Preterm heart in adult life: Cardiovascular magnetic resonance reveals distinct differences in left ventricular mass, geometry, and function," Circulation, vol. 127, no. 2, pp. 197-206, Jan. 2013.
54. H. Lombaert, J.-M. Peyrat, P. Croisille, S. Rapacchi, L. Fanton, F. Cheriet, P. Clarysse, I.Magnin, H. Delingette, and N. Ayache, "Human atlas of the cardiac fiber architecture: Study on a healthy population," IEEE Trans. Med. Imag., vol. 31, no. 7, pp. 1436-1447, Jul. 2012.
55. K. McLeod, C. Seiler, M. Sermnesant, and X. Pennec, "Spatio-temporal dimension reduction of cardiac motion for group-wise analysis and statistical testing," Med. Image Comput. Comput. Assist. Interv., vol. 16, no. Pt 2, pp. 501-508, 2013.
56. P. Medrano-Gracia, B. R. Cowan, B. Ambale-Venkatesh, D. A. Bluemke, J. Eng, J. P. Finn, C. G. Fonseca, J. A. C. Lima, A. and A. A. Young, "Left ventricular shape variation in asymptomatic populations: The multi-ethnic study of atherosclerosis," J. Cardiovasc. Magn. Reson., vol. 16, art. no. 1, p. 56, Jul. 2014.
57. Sunnybrook Health Sciences Centre. Cardiac MR left ventricle segmentation challenge [Online]. Available: http://smial.sri.utoronto. ca/LV-Challenge/Home.html
58. A. Suinesiaputra, B. R. Cowan, J. P. Finn, C. Fonseca, A. Kadish, D. Lee, P. Medrano-Gracia, S. Warfield, W. Tao, and A. Young, "Left ventricular segmentation challenge from cardiac MRI: A collation study," in Statistical Atlases and Computational Models of the Heart. Imaging and Modelling Challenges. New York, NY, USA: Springer, 2012.
59. C. Tobon-Gomez, M. De Craene, K. McLeod, L. Tautz, W. Shi, A. Hennemuth, A. Prakosa, H.Wang, G. Carr-White, S. Kapetanakis, A. Lutz, V. Rasche, T. Schaeffter, C. Butakoff, O. Friman, T.Mansi,M. Sermesant, X. Zhuang, S. Ourselin, H.-O. Peitgen, X. Pennec, R. Razavi, D. Rueckert, A. F. Frangi, and K. S. Rhode, "Benchmarking framework for myocardial tracking and deformation algorithms: An open access database," Med. Image Anal., vol. 17, no. 6, pp. 632-648, Aug. 2013.
60. R. Karim, R. J. Housden, M. Balasubramaniam, Z. Chen, D. Perry, A. Uddin, Y. Al-Beyatti, E. Palkhi, P. Acheampong, S. Obom, A. Hen-nemuth, Y. Lu, W. Bai, W. Shi, Y. Gao, H.-O. Peitgen, P. Radau, R. Razavi, A. Tannenbaum, D. Rueckert, J. Cates, T. Schaeffter, D. Peters, R. MacLeod, and K. Rhode, "Evaluation of current algorithms for segmentation of scar tissue from late gadolinium enhancement cardiovascular magnetic resonance of the left atrium: An open-access grand challenge," J. Cardiovasc. Magn. Reson., vol. 15, art. no. 105, 2013.
61. M. Schaap, C. T. Metz, T. van Walsum, A. G. van der Giessen, A. C. Weustink, N. R. Mollet, C. Bauer, H. Bogunović, C. Castro, X. Deng, E. Dikici, T. O'Donnell, M. Frenay, O. Friman, M. Hernández Hoyos, P. H. Kitslaar, K. Krissian, C. Kühnel, M. A. Luengo-Oroz, M. Orkisz, O. Smedby, M. Styner, A. Szymczak, H. Tek, C. Wang, S. K. Warfield, S. Zambal, Y. Zhang, G. P. Krestin, and W. J. Niessen, "Standardized evaluation methodology and reference database for evaluating coronary artery centerline extraction algorithms," Med. Image Anal., vol. 13, no. 5, pp. 701-714, Oct. 2009.
62. P. Welter, C. Hocken, T. M. Deserno, C. Grouls, and R. W. Günther, "Workflowmanagement of content-based image retrieval forCADsupport in PACS environments based on IHE," Int. J. Comput. Assist. Radiol. Surg., vol. 5, no. 4, pp. 393-400, Jul. 2010.
63. R. D. Britten, G. R. Christie, C. Little, A. K. Miller, C. Bradley, A. Wu, T. Yu, P. Hunter, and P. Nielsen, "FieldML, a proposed open standard for the physiome project for mathematical model representation," Med. Biol. Eng. Comput., vol. 51, no. 11, pp. 1191-1207, Nov. 2013.
64. R. R. Bond, D. D. Finlay, C. D. Nugent, and G. Moore, "A review of ECG storage formats," Int. J. Med. Inform., vol. 80, no. 10, pp. 681-697, Oct. 2011.
65. A. E. Buxton, H. Calkins, D. J. Callans, J. P. DiMarco, J. D. Fisher, H. L. Greene, D. E. Haines, D. L. Hayes, P. A. Heidenreich, J. M. Miller, A. Poppas, E. N. Prystowsky, M. H. Schoenfeld, P. J. Zimetbaum, D. C. Goff, F. L. Grover, D. J. Malenka, E. D. Peterson, M. J. Radford, and R. F. Redberg, "ACC/AHA/HRS 2006 key data elements and definitions for electrophysiological studies and procedures:Areport of the American college of cardiology/American heart association task force on clinical data standards (ACC/AHA/HRS writing committee to develop data standards on electrophysiology)," Circulation, vol. 114, no. 23, pp. 2534-2570, Dec. 2006.
66. R. Hinojar, R. Botnar, J. C. Kaski, S. Prasad, E. Nagel, and V. O. Puntmann, "Individualized cardiovascular risk assessment by cardiovascular magnetic resonance," Future Cardiol., vol. 10, no. 2, pp. 273-289, Mar. 2014.
67. A. Suinesiaputra, A. F. Frangi, T. A. M. Kaandorp, H. J. Lamb, J. J. Bax, J. H. C. Reiber, and B. P. F. Lelieveldt, "Automated detection of regional wall motion abnormalities based on a statistical model applied to multislice short-axis cardiac MR images," IEEE Trans. Med. Imag., vol. 28, no. 4, pp. 595-607, Apr. 2009.
68. J.-L. Vachiéry, P. Yerly, and S. Huez, "How to detect disease progression in pulmonary arterial hypertension," Eur. Respir. Rev., vol. 21, no. 123, pp. 40-47, Mar. 2012.
69. A. A. Young and A. F. Frangi, "Computational cardiac atlases: From patient to population and back," Exp. Physiol., vol. 94, no. 5, pp. 578-596, May. 2009.
70. C. Stratz, M. Amann, D. D. Berg, D. A. Morrow, F.-J. Neumann, and W. Hochholzer, "Novel biomarkers in cardiovascular disease: Research tools or ready for personalized medicine?," Cardiol. Rev., vol. 20, no. 3, pp. 111-117, 2012.
71. M. Ouzounian, D. S. Lee, A. O. Gramolini, A. Emili, M. Fukuoka, and P. P. Liu, "Predict, prevent and personalize: Genomic and proteomic approaches to cardiovascular medicine," Can. J. Cardiol., vol. 23, pp. 28A-33A, Aug. 2007.
72. K. Lekadir, C. Hoogendoorn, M. Pereanez, X. Alba, A.Pashaei, and A. F. Frangi, "Statistical personalization of ventricular fiber orientation using shape predictors," IEEE Trans. Med. Imag., vol. 33, no. 4, pp. 882-890, Apr. 2014.
73. P. Lamata, M. Sinclair, E. Kerfoot, A. Lee, A. Crozier, B. Blazevic, S. Land, A. J. Lewandowski, D. Barber, S. Niederer, and N. Smith, "An automatic service for the personalization of ventricular cardiac meshes," J. Roy. Soc. Interface, vol. 11, no. 91, p. 20131023, Feb. 2014.
74. M. W. Krueger, W. H. W. Schulze, K. S. Rhode, R. Razavi, G. Seemann, and O. Dössel, "Towards personalized clinical in-silico modeling of atrial anatomy and electrophysiology," Med. Biol. Eng. Comput., vol. 51, no. 11, pp. 1251-1260, Nov. 2013.
75. M. Sermesant, R. Chabiniok, P. Chinchapatnam, T. Mansi, F. Billet, P. Moireau, J. M. Peyrat, K. Wong, J. Relan, K. Rhode, M. Ginks, P. Lambiase, H. Delingette, M. Sorine, C. A. Rinaldi, D. Chapelle, R. Razavi, and N. Ayache, "Patient-specific electromechanical models of the heart for the prediction of pacing acute effects in CRT: A preliminary clinical validation," Med. Image Anal., vol. 16, no. 1, pp. 201-215, Jan. 2012.
76. J. Weese, A. Groth, H. Nickisch, H. Barschdorf, F. M. Weber, J. Velut, M. Castro, C. Toumoulin, J. L. Coatrieux, M. De Craene, G. Piella, C. Tobón-Gomez, A. F. Frangi, D. C. Barber, I. Valverde, Y. Shi, C. Staicu, A. Brown, P. Beerbaum, and D. R. Hose, "Generating anatomical models of the heart and the aorta frommedical images for personalized physiological simulations," Med. Biol. Eng. Comput., vol. 51, no. 11, pp. 1209-1219, Nov. 2013.