Racial variation in frequency and phenotypes of APC and MUTYH mutations in 6,169 individuals undergoing genetic testing

Genetics in Medicine

Volumn 17, Issue 10, 2015, Pages 815-821

  Inra, Jennifer A ^a,b   Steyerberg, Ewout W ^c   Grover, Shilpa ^a,b   McFarland, Ashley ^d   Syngal, Sapna ^a,b,e   Kastrinos, Fay ^d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d Department of Medicine   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

familial adenomatous polyposis; genetic testing; MUTYH associated polyposis; phenotype; race

Indexed keywords

APC PROTEIN; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE;

ADULT; AFRICAN AMERICAN; ARTICLE; ASIAN; CAUCASIAN; COLORECTAL CANCER; COLORECTAL POLYP; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ETHNIC DIFFERENCE; ETHNICITY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PHENOTYPE; PREVALENCE; RACE; ADENOMATOUS POLYPOSIS COLI; ALLELE; ANCESTRY GROUP; GENETICS; HETEROZYGOTE; MUTATION; MUTATION RATE; TUMOR VOLUME;

ADENOMATOUS POLYPOSIS COLI; ALLELES; CONTINENTAL POPULATION GROUPS; CROSS-SECTIONAL STUDIES; DNA GLYCOSYLASES; FEMALE; GENETIC TESTING; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; MUTATION RATE; PHENOTYPE; TUMOR BURDEN;

EID: 84938394693     PISSN: 10983600     EISSN: 15300366     Source Type: Journal    
DOI: 10.1038/gim.2014.199     Document Type: Article

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