Temporal variability of urinary concentrations of phthalate metabolites, parabens and benzophenone-3 in a Belgian adult population

Environmental Research

Volumn 142, Issue , 2015, Pages 414-423

  Dewalque, Lucas ^a   Pirard, Catherine ^a   Vandepaer, Sarah ^b   Charlier, Corinne ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Benzophenone 3; Intra individual variability; Parabens; Phthalates; Urinary spot samples

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; CREATININE; OXYBENZONE; PHTHALIC ACID; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; BENZOPHENONE DERIVATIVE; BIOLOGICAL MARKER; PHTHALIC ACID DERIVATIVE; POLLUTANT;

ADULT; ASSESSMENT METHOD; BIOMARKER; CONCENTRATION (COMPOSITION); MEASUREMENT METHOD; METABOLITE; ORGANIC COMPOUND; POLLUTION EXPOSURE; RISK FACTOR; TEMPORAL VARIATION; URINE;

ADULT; AGED; ARTICLE; BELGIAN; CLINICAL ARTICLE; CREATININE URINE LEVEL; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; LONG TERM EXPOSURE; MALE; METABOLITE; PREDICTIVE VALUE; PRIORITY JOURNAL; REPRODUCIBILITY; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TEMPORAL ANALYSIS; URINALYSIS; URINE LEVEL; ANALYSIS; BELGIUM; METABOLISM; POLLUTANT; URINE;

BELGIUM;

ADULT; BELGIUM; BENZOPHENONES; BIOMARKERS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HUMANS; PARABENS; PHTHALIC ACIDS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

EID: 84938381547     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2015.07.015     Document Type: Article

References (56)

1. Adibi J.J., Whyatt R.M., Williams P.L., Calafat A.M., Camann D., Herrick R., Nelson H., Bhat H.K., Perera F.P., Silva M.J., Hauser R. Characterization of phthalate exposure among pregnant women assessed by repeat air and urine samples. Environ. Health Perspect. 2008, 116:467-473.
2. Anderson W.A., Castle L., Scotter M.J., Massey R.C., Springall C. A biomarker approach to measuring human dietary exposure to certain phthalate diesters. Food Addit. Contam. 2001, 18:1068-1074.
3. Anderson W.A., Castle L., Hird S., Jeffery J., Scotter M.J. A twenty-volunteer study using deuterium labelling to determine the kinetics and fractional excretion of primary and secondary urinary metabolites of di-2-ethylhexylphthalate and di-iso-nonylphthalate. Food Chem. Toxicol. 2011, 49:2022-2029.
4. Baird D.D., Saldana T.M., Nepomnaschy P.A., Hoppin J.A., Longnecker M.P., Weinberg C.R., Wilcox A.J. Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage. J. Expo. Sci. Environ. Epidemiol. 2010, 20:169-175.
5. Bekö G., Weschler C.J., Langer S., Callesen M., Toftum J., Clausen G. Children's phthalate intakes and resultant cumulative exposures estimated from urine compared with estimates from dust ingestion, inhalation and dermal absorption in their homes and daycare centers. PLoS One 2013, 8:e62442.
6. Benson R. Hazard to the developing male reproductive system from cumulative exposure to phthalate esters-dibutyl phthalate, diisobutyl phthalate, butylbenzyl phthalate, diethylhexyl phthalate, dipentyl phthalate, and diisononyl phthalate. Regul. Toxicol. Pharmacol. 2009, 53:90-101.
7. Braun J.M., Smith K.W., Williams P.L., Calafat A.M., Berry K., Ehrlich S., Hauser R. Variability of urinary phthalate metabolite and bisphenol A concentrations before and during pregnancy. Environ. Health Perspect. 2012, 120:739-745.
8. Cantonwine D.E., Cordero J.F., Rivera-González L.O., Anzalota Del Toro L.V., Ferguson K.K., Mukherjee B., Calafat A.M., Crespo N., Jiménez-Vélez B., Padilla I.Y., Alshawabkeh A.N., Meeker J.D. Urinary phthalate metabolite concentrations among pregnant women in Northern Puerto Rico: distribution, temporal variability, and predictors. Environ. Int. 2014, 62:1-11.
9. Christiansen S., Scholze M., Dalgaard M., Vinggaard A.M., Axelstad M., Kortenkamp A., Hass U. Synergistic disruption of external male sex organ development by a mixture of four antiandrogens. Environ. Health Perspect. 2009, 117:1839-1846.
10. Cosmetic Ingredient Review Expert Panel Final amended report on the safety assessment of methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, and benzylparaben as used in cosmetic products. Int. J. Toxicol. 2008, 27:1-82.
11. Darbre P.D., Harvey P.W. Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks. J. Appl. Toxicol. 2008, 28:561-578.
12. DEMOCOPHES-National Report on Human Biomonitoring in Mothers and Children - Belgium, 2012; . http://www.eu-hbm.info.
13. Dewalque L., Pirard C., Charlier C. Measurement of urinary biomarkers of parabens, benzophenone-3, and phthalates in a Belgian population. Biomed. Res. Int 2014, 649314.
14. Dewalque L., Charlier C., Pirard C. Estimated daily intake and cumulative risk assessment of phthalate diesters in a Belgian general population. Toxicol. Lett. 2014, 231:161-168.
15. Dewalque L., Pirard C., Dubois N., Charlier C. Simultaneous determination of some phthalate metabolites, parabens and benzophenone-3 in urine by ultra high pressure liquid chromatography tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2014, 949-950:37-47.
16. Engel L.S., Buckley J.P., Yang G., Liao L.M., Satagopan J., Calafat A.M., Matthews C.E., Cai Q., Ji B.T., Cai H., Engel S.M., Wolff M.S., Rothman N., Zheng W., Xiang Y.B., Shu X.O., Gao Y.T., Chow W.H. Predictors and variability of repeat measurements of urinary phenols and parabens in a cohort of shanghai women and men. Environ. Health Perspect. 2014, 122:733-740.
17. European Food Safety Authorities Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the commission related to bis(2-ethylhexyl)phthalate (DEHP) for use in food contact materials. EFSA J. 2005, 243:1-20.
18. European Food Safety Authorities Opinion of the scientific panel on food additives, flavourings, processing aids and material in contact with food (AFC) on a request from the commission related to di-butylphthalate (DBP) for use in food contact materials. EFSA J. 2005, 242:1-17.
19. European Food Safety Authorities Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the commission related to butylbenzylphthalate (BBP) for use in food contact materials. EFSA J. 2005, 241:1-14.
20. Ferguson K.K., McElrath T.F., Ko Y.A., Mukherjee B., Meeker J.D. Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth. Environ. Int. 2014, 70:118-124.
21. Fisher M., Arbuckle T.E., Mallick R., LeBlanc A., Hauser R., Feeley M., Koniecki D., Ramsay T., Provencher G., Bérubé R., Walker M. Bisphenol A and phthalate metabolite urinary concentrations: Daily and across pregnancy variability. J. Expo. Sci. Environ. Epidemiol 2015, 25:231-239.
22. Frederiksen H., Jørgensen N., Andersson A.M. Correlations between phthalate metabolites in urine, serum, and seminal plasma from young danish men determined by isotope dilution liquid chromatography tandem mass spectrometry. J. Anal. Toxicol. 2010, 34:400-410.
23. Frederiksen H., Kranich S.K., Jørgensen N., Taboureau O., Petersen J.H., Andersson A.M. Temporal variability in urinary phthalate metabolite excretion based on spot, morning, and 24-h urine samples: considerations for epidemiological studies. Environ. Sci. Technol. 2013, 47:958-967.
24. Fromme H., Bolte G., Koch H.M., Angerer J., Boehmer S., Drexler H., Mayer R., Liebl B. Occurrence and daily variation of phthalate metabolites in the urine of an adult population. Int. J. Hyg. Environ. Health 2007, 210:21-33.
25. Gonzalez H., Farbrot A., Larkö O., Wennberg A.M. Percutaneous absorption of the sunscreen benzophenone-3 after repeated whole-body applications, with and without ultraviolet irradiation. Br. J. Dermatol. 2006, 154:337-340.
26. Hankinson S.E., Manson J.E., Spiegelman D., Willett W.C., Longcope C., Speizer F.E. Reproducibility of plasma hormone levels in postmenopausal women over a 2-3-year period. Cancer Epidemiol. Biomarkers Prev. 1995, 4:649-654.
27. Hauser R., Meeker J.D., Park S., Silva M.J., Calafat A.M. Temporal variability of urinary phthalate metabolite levels in men of reproductive age. Environ. Health Perspect. 2004, 112:1734-1740.
28. Hauser R., Meeker J.D., Singh N.P., Silva M.J., Ryan L., Duty S., Calafat A.M. DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites. Hum. Reprod. 2007, 22:688-695.
29. Hoberman A.M., Schreur D.K., Leazer T., Daston G.P., Carthew P., Re T., Loretz L., Mann P. Lack of effect of butylparaben and methylparaben on the reproductive system in male rats. Birth Defects Res. B Dev. Reprod. Toxicol. 2008, 83:123-133.
30. Hoppin J.A., Brock J.W., Davis B.J., Baird D.D. Reproducibility of urinary phthalate metabolites in first morning urine samples. Environ. Health Perspect. 2002, 110:515-518.
31. Hornung R.W., Reed L.D. Estimation of average concentration in the presence of nondetectable values. Appl. Occup. Environ. Hyg. 1990, 5:46-51.
32. Howdeshell K.L., Wilson V.S., Furr J., Lambright C.R., Rider C.V., Blystone C.R., Hotchkiss A.K., Gray L.E. A mixture of five phthalate esters inhibits fetal testicular testosterone production in the Sprague-Dawley rat in a cumulative, dose-additive manner. Toxicol. Sci. 2008, 105:153-165.
33. Koch H.M., Christensen K.L., Harth V., Lorber M., Brüning T. Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses. Arch. Toxicol. 2012, 86:1829-1839.
34. Koch H.M., Aylward L.L., Hays S.M., Smolders R., Moos R.K., Cocker J., Jones K., Warren N., Levy L., Bevan R. Inter- and intra-individual variation in urinary biomarker concentrations over a 6-day sampling period. Part 2: Personal care product ingredients. Toxicol Lett. 2014, 231:261-269.
35. Kortenkamp A., Faust M. Combined exposures to anti-androgenic chemicals: steps towards cumulative risk assessment. Int. J. Androl. 2010, 33:463-474.
36. Kranich S.K., Frederiksen H., Andersson A.M., Jørgensen N. Estimated daily intake and hazard quotients and indices of phthtalate diesters for young Danish men. Environ. Sci. Technol. 2014, 48:706-712.
37. Ma W.L., Wang L., Guo Y., Liu L.Y., Qi H., Zhu N.Z., Gao C.J., Li Y.F., Kannan K. Urinary concentrations of parabens in chinese young adults: implications for human exposure. Arch. Environ. Contam. Toxicol. 2013, 65:611-618.
38. Marcus M., Christensen K.Y., Manatunga A., Rudra C.B., Brock J.W., Small C.M. Variability of phthalate monoester levels in daily first-morning urine from adult women: a pilot study. Rev. Environ. Health 2010, 25:359-368.
39. Meeker J.D., Yang T., Ye X., Calafat A.M., Hauser R. Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damage. Environ. Health Perspect. 2011, 119:252-257.
40. Meeker J.D., Calafat A.M., Hauser R. Urinary phthalate metabolites and their biotransformation products: predictors and temporal variability among men and women. J. Expo. Sci. Environ. Epidemiol. 2012, 22:376-385.
41. Meeker J.D., Cantonwine D.E., Rivera-González L.O., Ferguson K.K., Mukherjee B., Calafat A.M., Ye X., Anzalota Del Toro L.V., Crespo-Hernández N., Jiménez-Vélez B., Alshawabkeh A.N., Cordero J.F. Distribution, variability, and predictors of urinary concentrations of phenols and parabens among pregnant women in Puerto Rico. Environ. Sci. Technol. 2013, 47:3439-3447.
42. Peck J.D., Sweeney A.M., Symanski E., Gardiner J., Silva M.J., Calafat A.M., Schantz S.L. Intra- and inter-individual variability of urinary phthalate metabolite concentrations in Hmong women of reproductive age. J. Expo. Sci. Environ. Epidemiol. 2010, 20:90-100.
43. Philippat C., Wolff M.S., Calafat A.M., Ye X., Bausell R., Meadows M., Stone J., Slama R., Engel S.M. Prenatal exposure to environmental phenols: concentrations in amniotic fluid and variability in urinary concentrations during pregnancy. Environ. Health. Perspect. 2013, 121:1225-1231.
44. Preau J.L., Wong L.Y., Silva M.J., Needham L.L., Calafat A.M. Variability over 1 week in the urinary concentrations of metabolites of diethyl phthalate and di(2-ethylhexyl) phthalate among eight adults: an observational study. Environ. Health Perspect. 2010, 118:1748-1754.
45. Rosner B. Fundamentals of biostatistics 2011, Brooks/Cole, Boston, M.A.
46. Rudel R.A., Gray J.M., Engel C.L., Rawsthorne T.W., Dodson R.E., Ackerman J.M., Rizzo J., Nudelman J.L., Brody J.G. Food packaging and bisphenol A and bis(2-ethyhexyl) phthalate exposure: findings from a dietary intervention. Environ. Health Perspect. 2011, 119:914-920.
47. Schlumpf M., Cotton B., Conscience M., Haller V., Steinmann B., Lichtensteiger W. In vitro and in vivo estrogenicity of UV screens. Environ. Health Perspect. 2001, 109:239-244.
48. Shirai S., Suzuki Y., Yoshinaga J., Shiraishi H., Mizumoto Y. Urinary excretion of parabens in pregnant Japanese women. Reprod. Toxicol. 2013, 35:96-101.
49. Smith K.W., Braun J.M., Williams P.L., Ehrlich S., Correia K.F., Calafat A.M., Ye X., Ford J., Keller M., Meeker J.D., Hauser R. Predictors and variability of urinary paraben concentrations in men and women, including before and during pregnancy. Environ. Health Perspect. 2012, 120:1538-1543.
50. Suzuki Y., Niwa M., Yoshinaga J., Watanabe C., Mizumoto Y., Serizawa S., Shiraishi H. Exposure assessment of phthalate esters in Japanese pregnant women by using urinary metabolite analysis. Environ. Health Prev. Med. 2009, 14:180-187.
51. Swan S.H., Main K.M., Liu F., Stewart S.L., Kruse R.L., Calafat A.M., Mao C.S., Redmon J.B., Ternand C.L., Sullivan S., Teague J.L. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ. Health Perspect. 2005, 113:1056-1061.
52. Søeborg T., Frederiksen H., Andersson A.M. Considerations for estimating daily intake values of non-persistent environmental endocrine disruptors based on urinary biomonitoring data. Reproduction 2013, 147:455-463.
53. Teitelbaum S.L., Britton J.A., Calafat A.M., Ye X., Silva M.J., Reidy J.A., Galvez M.P., Brenner B.L., Wolff M.S. Temporal variability in urinary concentrations of phthalate metabolites, phytoestrogens and phenols among minority children in the United States. Environ. Res. 2008, 106:257-269.
54. Townsend M.K., Franke A.A., Li X., Hu F.B., Eliassen A.H. Within-person reproducibility of urinary bisphenol A and phthalate metabolites over a 1 to 3 year period among women in the Nurses' Health Studies: a prospective cohort study. Environ. Health 2013, 12:80.
55. Watkins D.J., Eliot M., Sathyanarayana S., Calafat A.M., Yolton K., Lanphear B.P., Braun J.M. Variability and predictors of urinary concentrations of phthalate metabolites during early childhood. Environ. Sci. Technol. 2014, 48:8881-8890.
56. Wittassek M., Koch H.M., Angerer J., Brüning T. Assessing exposure to phthalates-the human biomonitoring approach. Mol. Nutr. Food Res. 2011, 55:31-37.