-
1
-
-
0242414632
-
Hyperosmolar mannitol simulates expression of aquaporins 4 and 9 through ap38 mitogen-activated protein kinase-dependent pathwayin rat astrocytes
-
Arima, H., Yamamoto, N., Sobue, K., Umenishi, F., Tada, T., Katsuya, H., et al. (2003). Hyperosmolar mannitol simulates expression of aquaporins 4 and 9 through a p38 mitogen-activated protein kinase-dependent pathwayin rat astrocytes. J. Biol. Chem. 278, 44525-44534. doi: 10.1074/jbc.M304368200.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44525-44534
-
-
Arima, H.1
Yamamoto, N.2
Sobue, K.3
Umenishi, F.4
Tada, T.5
Katsuya, H.6
-
2
-
-
84864352807
-
Rapid transgene expression in multiple precursor cell types of adult rat subventricular zone mediated by adeno-associated type 1 vectors
-
Bockstael, O., Melas, C., Pythoud, C., Levivier, M., McCarty, D., Samulski, R. J., et al. (2012). Rapid transgene expression in multiple precursor cell types of adult rat subventricular zone mediated by adeno-associated type 1 vectors. Hum. Gene Ther. 23, 742-753. doi: 10.1089/hum.2011.216.
-
(2012)
Hum. Gene Ther.
, vol.23
, pp. 742-753
-
-
Bockstael, O.1
Melas, C.2
Pythoud, C.3
Levivier, M.4
McCarty, D.5
Samulski, R.J.6
-
3
-
-
84897859634
-
Microglial phagocytosis of live neurons
-
Brown, G. C., and Neher, J. J. (2014). Microglial phagocytosis of live neurons. Nat.Rev. Neurosci. 15,209-216. doi: 10.1038/nrn3710.
-
(2014)
Nat.
, vol.15
, pp. 209-216
-
-
Brown, G.C.1
Neher, J.J.2
-
4
-
-
84880593182
-
ScAAV2/9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease
-
Bucher, T., Colle, M. A., Wakeling, E., Dubreil, L., Fyfe, J., Briot-Nivard, D., et al. (2013). scAAV2/9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease. Hum. Gene Ther. 24, 670-682. doi: 10.1089/hum.2012.218.
-
(2013)
Hum. Gene Ther.
, vol.24
, pp. 670-682
-
-
Bucher, T.1
Colle, M.A.2
Wakeling, E.3
Dubreil, L.4
Fyfe, J.5
Briot-Nivard, D.6
-
5
-
-
84871908609
-
An adeno-associatedvirus-basedintracellular sensor ofpathological nuclear factor-kappaB activation for disease-inducible gene transfer
-
Chtarto, A., Bockstael, O., Gebara, E., Vermoesen, K., Melas, C., Pythoud, C., et al. (2013).An adeno-associatedvirus-basedintracellular sensor ofpathological nuclear factor-kappaB activation for disease-inducible gene transfer. PLoS ONE 8:e53156. doi: 10.1371/journal.pone.0053156.
-
(2013)
Plos ONE
, vol.8
-
-
Chtarto, A.1
Bockstael, O.2
Gebara, E.3
Vermoesen, K.4
Melas, C.5
Pythoud, C.6
-
6
-
-
84856975718
-
Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV2/9
-
Dalkara, D., Byrne, L. C., Lee, T., Hoffmann, N. V., Schaffer, D. V., and Flannery, J. G. (2012). Enhanced gene delivery to the neonatal retina through systemic administration of tyrosine-mutated AAV2/9. Gene Ther. 19, 176-181. doi: 10.1038/gt.2011.163.
-
(2012)
Gene Ther
, vol.19
, pp. 176-181
-
-
Dalkara, D.1
Byrne, L.C.2
Lee, T.3
Hoffmann, N.V.4
Schaffer, D.V.5
Flannery, J.G.6
-
7
-
-
84859743388
-
Systemic scAAV2/9 variantmediatesbraintransductionin newbornrhesusmacaques
-
Dehay, B., Dalkara, D., Dovero, S., Li, Q., and Bezard, E. (2012). Systemic scAAV2/9 variantmediatesbraintransductionin newbornrhesusmacaques. Sci. Rep. 2:253. doi: 10.1038/srep00253.
-
(2012)
Sci. Rep.
, vol.2
-
-
Dehay, B.1
Dalkara, D.2
Dovero, S.3
Li, Q.4
Bezard, E.5
-
8
-
-
84881427177
-
Parkinson disease: From pathology to molecular disease mechanisms
-
Dexter, D. T., and Jenner, P. (2013). Parkinson disease: from pathology to molecular disease mechanisms. Free Radic. Biol. Med. 62, 132-144. doi: 10.1016/j.freeradbiomed.2013.01.018.
-
(2013)
Free Radic. Biol. Med.
, vol.62
, pp. 132-144
-
-
Dexter, D.T.1
Jenner, P.2
-
9
-
-
67649861393
-
Intravenous administration of self-complementary AAV2/9 enables transgene delivery to adult motor neurons
-
Duque, S., Joussemet, B., Riviere, C., Marais, T., Dubreil, L., Douar, A. M., etal. (2009). Intravenous administration of self-complementary AAV2/9 enables transgene delivery to adult motor neurons. Mol. Ther. 17, 1187-1196. doi: 10.1038/mt.2009.71.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1187-1196
-
-
Duque, S.1
Joussemet, B.2
Riviere, C.3
Marais, T.4
Dubreil, L.5
Douar, A.M.6
-
10
-
-
60149106907
-
Intravascular AAV2/9 preferentially targets neonatal neurons and adult astrocytes
-
Foust, K. D., Nurre, E., Montgomery, C. L., Hernandez, A., Chan, C. M., and Kaspar, B. K. (2009). Intravascular AAV2/9 preferentially targets neonatal neurons and adult astrocytes. Nat. Biotechnol. 27, 59-65. doi: 10.1038/nbt.1515.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 59-65
-
-
Foust, K.D.1
Nurre, E.2
Montgomery, C.L.3
Hernandez, A.4
Chan, C.M.5
Kaspar, B.K.6
-
11
-
-
77955634419
-
Restoration of central nervous system alpha-N-acetylglucosaminidase activity and therapeutic benefits in mucopolysaccharidosis IIIB mice by a single intracisternal recombinant adeno-associated viral type 2 vector delivery
-
Fu, H., Dirosario, J., Kang, L., Muenzer, J., and Mccarty, D. M. (2010). Restoration of central nervous system alpha-N-acetylglucosaminidase activity and therapeutic benefits in mucopolysaccharidosis IIIB mice by a single intracisternal recombinant adeno-associated viral type 2 vector delivery. J. Gene Med. 12, 624-633. doi: 10.1002/jgm.1480.
-
(2010)
J. Gene Med.
, vol.12
, pp. 624-633
-
-
Fu, H.1
Dirosario, J.2
Kang, L.3
Muenzer, J.4
McCarty, D.M.5
-
12
-
-
79957882063
-
Correction of neurological disease of mucopolysaccharidosis IIIB in adult mice by rAAV2/9 trans-blood-brain barrier gene delivery
-
Fu, H., Dirosario, J., Killedar, S., Zaraspe, K., and Mccarty, D. M. (2011). Correction of neurological disease of mucopolysaccharidosis IIIB in adult mice by rAAV2/9 trans-blood-brain barrier gene delivery. Mol. Ther. 19, 1025-1033. doi: 10.1038/mt.2011.34.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1025-1033
-
-
Fu, H.1
Dirosario, J.2
Killedar, S.3
Zaraspe, K.4
McCarty, D.M.5
-
13
-
-
0347286956
-
Self- complementary adeno-associated virus serotype 2 vector: Global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain
-
Fu, H., Muenzer, J., Samulski, R. J., Breese, G., Sifford, J., Zeng, X., et al. (2003). Self- complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain. Mol. Ther. 8,911-917. doi: 10.1016/j.ymthe.2003.08.021.
-
(2003)
Mol. Ther.
, vol.8
, pp. 911-917
-
-
Fu, H.1
Muenzer, J.2
Samulski, R.J.3
Breese, G.4
Sifford, J.5
Zeng, X.6
-
14
-
-
79957888016
-
Preclinical differences of intravascular AAV2/9 delivery to neurons and glia: A comparative study of adult mice and nonhuman primates
-
Gray, S. J., Matagne, V., Bachaboina, L., Yadav, S., Ojeda, S. R., and Samulski, R. J. (2011). Preclinical differences of intravascular AAV2/9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates. Mol. Ther. 19, 1058-1069. doi: 10.1038/mt.2011.72.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1058-1069
-
-
Gray, S.J.1
Matagne, V.2
Bachaboina, L.3
Yadav, S.4
Ojeda, S.R.5
Samulski, R.J.6
-
15
-
-
84875925195
-
Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates
-
Gray, S. J., Nagabhushan, K. S., McCown, T. J., and Jude, S. R. (2013). Global CNS gene delivery and evasion of anti-AAV-neutralizing antibodies by intrathecal AAV administration in non-human primates. Gene Ther. 20, 450-459. doi: 10.1038/gt.2012.101.
-
(2013)
Gene Ther
, vol.20
, pp. 450-459
-
-
Gray, S.J.1
Nagabhushan, K.S.2
McCown, T.J.3
Jude, S.R.4
-
16
-
-
84865123660
-
A perivascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta
-
Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., et al. (2012). A perivascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Sci. Transl. Med. 4:147ra111. doi: 10.1126/scitranslmed.3003748.
-
(2012)
Sci. Transl. Med
, vol.4
-
-
Iliff, J.J.1
Wang, M.2
Liao, Y.3
Plogg, B.A.4
Peng, W.5
Gundersen, G.A.6
-
17
-
-
80055104131
-
A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse
-
Liu, L., and Duff, K. (2008). A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse. J. Vis. Exp. 21, 960. doi: 10.3791/960.
-
(2008)
J. Vis. Exp.
, vol.21
-
-
Liu, L.1
Duff, K.2
-
18
-
-
77958099436
-
Characterization of a recombinant adeno-associated virus type 2. Reference Standard Material
-
Lock, M., McGorray, S., Auricchio, A., Ayuso, E., Beecham, E. J., Blouin-Tavel, V., et al. (2010). Characterization of a recombinant adeno-associated virus type 2. Reference Standard Material. Hum. Gene Ther. 21, 1273-1285. doi: 10.1089/hum.2009.223.
-
(2010)
Hum. Gene Ther.
, vol.21
, pp. 1273-1285
-
-
Lock, M.1
McGorray, S.2
Auricchio, A.3
Ayuso, E.4
Beecham, E.J.5
Blouin-Tavel, V.6
-
19
-
-
84875928941
-
Microglia and monocyte- derived macrophages: Functionally distinct populations that act in concert in CNS plasticity and repair
-
London, A., Cohen, M., and Schwartz, M. (2013). Microglia and monocyte- derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair. Front. Cell. Neurosci. 7:34. doi: 10.3389/fncel.2013.00034.
-
(2013)
Front. Cell. Neurosci.
, vol.7
-
-
London, A.1
Cohen, M.2
Schwartz, M.3
-
20
-
-
70449720981
-
Mannitol-facilitated CNS entry of rAAV2 vector significantly delayed the neurological disease progression in MPS IIIB mice
-
Mccarty, D. M., Dirosario, J., Gulaid, K., Muenzer, J., and Fu, H. (2009). Mannitol-facilitated CNS entry of rAAV2 vector significantly delayed the neurological disease progression in MPS IIIB mice. Gene Ther. 16, 1340-1352. doi: 10.1038/gt.2009.85.
-
(2009)
Gene Ther
, vol.16
, pp. 1340-1352
-
-
McCarty, D.M.1
Dirosario, J.2
Gulaid, K.3
Muenzer, J.4
Fu, H.5
-
21
-
-
0346777307
-
Adeno-associated virus terminal repeat (TR) mutant generates self- complementary vectors to overcome the rate-limiting step to transduction in vivo
-
Mccarty, D. M., Fu, H., Monahan, P. E., Toulson, C. E., Naik, P., and Samulski, R. J. (2003). Adeno-associated virus terminal repeat (TR) mutant generates self- complementary vectors to overcome the rate-limiting step to transduction in vivo. GeneTher. 10, 2112-2118. doi: 10.1038/sj.gt.3302134.
-
(2003)
Genether
, vol.10
, pp. 2112-2118
-
-
McCarty, D.M.1
Fu, H.2
Monahan, P.E.3
Toulson, C.E.4
Naik, P.5
Samulski, R.J.6
-
22
-
-
80051764731
-
Drug transport in brain via the cerebrospinal fluid
-
Pardridge, W. M. (2011). Drug transport in brain via the cerebrospinal fluid. Fluids Barriers CNS 8:7. doi: 10.1186/2045-8118-8-7.
-
(2011)
Fluids Barriers CNS
, vol.8
-
-
Pardridge, W.M.1
-
23
-
-
0030017136
-
Seizure activity results in a rapid induction of nuclear factor-kappa B in adult but not juvenile rat limbic structures
-
Rong, Y., and Baudry, M. (1996). Seizure activity results in a rapid induction of nuclear factor-kappa B in adult but not juvenile rat limbic structures. J. Neurochem. 67, 662-668. doi: 10.1046/j.1471-4159.1996.67020662.x
-
(1996)
J. Neurochem.
, vol.67
, pp. 662-668
-
-
Rong, Y.1
Baudry, M.2
-
24
-
-
84877847142
-
Strong cortical and spinal cord transduction after AAV7 andAAV2/9 delivery into the cerebrospinal fluid of nonhuman primates
-
Samaranch, L., Salegio, E. A., San, S. W., Kells, A. P., Bringas, J. R., Forsayeth, J., et al. (2013). Strong cortical and spinal cord transduction after AAV7 andAAV2/9 delivery into the cerebrospinal fluid of nonhuman primates. Hum. Gene Ther. 24, 526-532. doi: 10.1089/hum.2013.005.
-
(2013)
Hum. Gene Ther.
, vol.24
, pp. 526-532
-
-
Samaranch, L.1
Salegio, E.A.2
San, S.W.3
Kells, A.P.4
Bringas, J.R.5
Forsayeth, J.6
-
25
-
-
84860171925
-
Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates
-
Samaranch, L., Salegio, E. A., San, S. W., Kells, A. P., Foust, K. D., Bringas, J. R., etal. (2012). Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates. Hum. Gene Ther. 23, 382-389. doi: 10.1089/hum.2011.200.
-
(2012)
Hum. Gene Ther.
, vol.23
, pp. 382-389
-
-
Samaranch, L.1
Salegio, E.A.2
San, S.W.3
Kells, A.P.4
Foust, K.D.5
Bringas, J.R.6
-
26
-
-
84893307092
-
AAV2/9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction
-
Samaranch, L., San, S. W., Kells, A. P., Salegio, E. A., Heller, G., Bringas, J. R., et al. (2014). AAV2/9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction. Mol. Ther. 22, 329-337. doi: 10.1038/mt.2013.266.
-
(2014)
Mol. Ther.
, vol.22
, pp. 329-337
-
-
Samaranch, L.1
San, S.W.2
Kells, A.P.3
Salegio, E.A.4
Heller, G.5
Bringas, J.R.6
-
27
-
-
84894646177
-
The resolution of neuroinflammation in neurodegeneration: Leukocyte recruitment via the choroid plexus
-
Schwartz, M., and Baruch, K. (2014). The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus. EMBO J. 33, 7-22. doi: 10.1002/embj.201386609.
-
(2014)
EMBO J
, vol.33
, pp. 7-22
-
-
Schwartz, M.1
Baruch, K.2
-
28
-
-
67649804600
-
Enhanced microglial activation and proinflamma- tory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a two-hit’ seizure model
-
Somera-Molina, K. C., Nair, S., Van Eldik, L. J., Watterson, D. M., and Wainwright, M. S. (2009). Enhanced microglial activation and proinflamma- tory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a two-hit’ seizure model. Brain Res. 1282, 162-172. doi: 10.1016/j.brainres.2009.05.073.
-
(2009)
Brain Res
, vol.1282
, pp. 162-172
-
-
Somera-Molina, K.C.1
Nair, S.2
Van Eldik, L.J.3
Watterson, D.M.4
Wainwright, M.S.5
-
29
-
-
77953536098
-
The control of kainic acid-induced status epilepticus
-
Vermoesen, K., Smolders, I., Massie, A., Michotte, Y., and Clinckers, R. (2010). The control of kainic acid-induced status epilepticus. Epilepsy Res. 90, 164-166. doi: 10.1016/j.eplepsyres.2010.04.001.
-
(2010)
Epilepsy Res
, vol.90
, pp. 164-166
-
-
Vermoesen, K.1
Smolders, I.2
Massie, A.3
Michotte, Y.4
Clinckers, R.5
-
30
-
-
60849133327
-
Development of spontaneous recurrent seizures after kainate-induced status epilepticus
-
Williams, P. A., White, A. M., Clark, S., Ferraro, D. J., and Swiercz, W. (2009). Development of spontaneous recurrent seizures after kainate-induced status epilepticus. J. Neurosci. 29, 2103-2112. doi: 10.1523/JNEUR0SCI.0980-08.2009.
-
(2009)
J. Neurosci.
, vol.29
, pp. 2103-2112
-
-
Williams, P.A.1
White, A.M.2
Clark, S.3
Ferraro, D.J.4
Swiercz, W.5
-
31
-
-
54549096772
-
Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression
-
Zhong, L., Li, B., Jayandharan, G., Mah, C. S., Govindasamy, L., Agbandje-McKenna, M., et al. (2008). Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression. Virology 381,194-202. doi: 10.1016/j.virol.2008.08.027
-
(2008)
Virology
, vol.381
, pp. 194-202
-
-
Zhong, L.1
Li, B.2
Jayandharan, G.3
Mah, C.S.4
Govindasamy, L.5
Agbandje-McKenna, M.6
|