Melatonin Protects Methamphetamine-Induced Neuroinflammation Through NF-κB and Nrf2 Pathways in Glioma Cell Line

Neurochemical Research

Volumn 40, Issue 7, 2015, Pages 1448-1456

  Jumnongprakhon, Pichaya ^a   Govitrapong, Piyarat ^b   Tocharus, Chainarong ^a   Pinkaew, Decha ^a   Tocharus, Jiraporn ^a  

^a CHIANG MAI UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Inflammation; Melatonin; Methamphetamine; Nuclear factor erythroid 2 (Nrf2); Nuclear factor B (NF B); Oxidative stress

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MELATONIN; METHAMPHETAMINE; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; NFE2L2 PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GLIOMA CELL LINE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BRAIN TUMOR; DOWN REGULATION; GLIOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

RATTUS;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; GLIOMA; MELATONIN; METHAMPHETAMINE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; RATS; UP-REGULATION;

EID: 84938208622     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-015-1613-2     Document Type: Article

References (50)

1. Halpin LE, Collins SA, Yamamoto BK (2014) Neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine. Life Sci 97(1):37–44
2. Panenka WJ, Procyshyn RM, Lecomte T, MacEwan GW, Flynn SW, Honer WG, Barr AM (2013) Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings. Drug Alcohol Depend 129(3):167–179
3. Snider SE, Hendrick ES, Beardsley PM (2013) Glial cell modulators attenuate methamphetamine self-administration in the rat. Eur J Pharmacol 701(1):124–130
4. Robson MJ, Turner RC, Naser ZJ, McCurdy CR, Huber JD, Matsumoto RR (2013) SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation. Exp Neurol 247:134–142
5. Cadet JL, Krasnova IN (2009) Molecular bases of methamphetamine-induced neurodegeneration. Int Rev Neurobiol 88(9):101–119
6. Permpoonputtana K, Mukda S, Govitrapong P (2012) Effect of melatonin on D-amphetamine-induced neuroglial alterations in postnatal rat hippocampus and prefrontal cortex. Neurosci Lett 524(1):1–4
7. Tocharus J, Chongthammakun S, Govitrapong P (2008) Melatonin inhibits amphetamine-induced nitric oxide synthase mRNA overexpression in microglial cell lines. Neurosci Lett 439(2):134–137
8. Tocharus J, Khonthun C, Chongthammakun S, Govitrapong P (2010) Melatonin attenuates methamphetamine-induced overexpression of pro-inflammatory cytokines in microglial cell lines. J Pineal Res 48(4):347–352
9. Coelho-Santos V, Goncalves J, Fontes-Ribeiro C, Silva AP (2012) Prevention of methamphetamine-induced microglial cell death by TNF-alpha and IL-6 through activation of the JAK-STAT pathway. J Neuroinflammation 9(103):1742–2094
10. Li YH, Wang HJ, Qiao DF (2008) Effect of methamphetamine on the microglial cells and activity of nitric oxide synthases in rat striatum. Nan Fang Yi Ke Da Xue Xue Bao 28(10):1789–1791
11. Friend D, Keefe K (2013) Glial reactivity in resistance to methamphetamine-induced neurotoxicity. J Neurochem 125(4):566–574
12. Kelly K, Miller D, Bowyer J, O’Callaghan J (2012) Chronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamine. J Neurochem 122(5):995–1009
13. Huang Y, Wu C, Lin T, Wang J (2009) Methamphetamine induces heme oxygenase-1 expression in cortical neurons and glia to prevent its toxicity. Toxicol Appl Pharmacol 240(3):315–326
14. Marshall JF, O’Dell SJ (2012) Methamphetamine influences on brain and behavior: unsafe at any speed? Trends Neurosci 35(9):536–545
15. Ares-Santos S, Granado N, Moratalla R (2013) The role of dopamine receptors in the neurotoxicity of methamphetamine. J Intern Med 273(5):437–453
16. Thrash B, Thiruchelvan K, Ahuja M, Suppiramaniam V, Dhanasekaran M (2009) Methamphetamine-induced neurotoxicity: the road to Parkinson’s disease. Pharmacol Rep 61(6):966–977
17. Kita T, Takeshima M, Wagner GC, Hozumi H, Miyazaki I, Asanuma M (2008) New perspectives on the mechanism of methamphetamine-induced neurotoxicity. Nihon Shinkei Seishin Yakurigaku Zasshi 28(2):49–61
18. Sekine Y, Ouchi Y, Sugihara G, Takei N, Yoshikawa E, Nakamura K, Iwata Y, Tsuchiya KJ, Suda S, Suzuki K, Kawai M, Takebayashi K, Yamamoto S, Matsuzaki H, Ueki T, Mori N, Gold MS, Cadet JL (2008) Methamphetamine causes microglial activation in the brains of human abusers. J Neurosci 28(22):5756–5761
19. Fantegrossi WE, Ciullo JR, Wakabayashi KT, De La Garza R II, Traynor JR, Woods JH (2008) A comparison of the physiological, behavioral, neurochemical and microglial effects of methamphetamine and 3,4-methylenedioxymethamphetamine in the mouse. Neuroscience 151(2):533–543
20. Thomas DM, Walker PD, Benjamins JA, Geddes TJ, Kuhn DM (2004) Methamphetamine neurotoxicity in dopamine nerve endings of the striatum is associated with microglial activation. J Pharmacol Exp Ther 311(1):1–7
21. Lavoie MJ, Card JP, Hastings TG (2004) Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity. Exp Neurol 187(1):47–57
22. Hoesel B, Schmid JA (2013) The complexity of NF-kappaB signaling in inflammation and cancer. Mol Cancer 12(86):1476–4598
23. Niederberger E, Geisslinger G (2013) Proteomics and NF-kappaB: an update. Expert Rev Proteomics 10(2):189–204
24. Siomek A (2012) NF-kappaB signaling pathway and free radical impact. Acta Biochim Pol 59(3):323–331
25. Gan L, Johnson JA (2013) Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases. Biochim Biophys Acta 13:366–369
26. Bryan HK, Olayanju A, Goldring CE, Park BK (2013) The Nrf2 cell defence pathway: keap1-dependent and -independent mechanisms of regulation. Biochem Pharmacol 85(6):705–717
27. Sandberg M, Patil J, D’Angelo B, Weber SG, Mallard C (2013) NRF2-regulation in brain health and disease: Implication of cerebral inflammation. Neuropharmacology 19:298–306
28. Zenkov NK, Menshchikova EB, Tkachev VO (2013) Keap1/Nrf2/ARE redox-sensitive signaling system as a pharmacological target. Biochemistry 78(1):19–36
29. Sarlak G, Jenwitheesuk A, Chetsawang B, Govitrapong P (2013) Effects of melatonin on nervous system aging: neurogenesis and neurodegeneration. J Pharmacol Sci 123(1):9–24
30. Arushanian EB, Naumov SS (2013) Anti-inflammatory potential of melatonin. Klin Med 91(7):18–22
31. Jumnongprakhon P, Govitrapong P, Tocharus C, Tungkum W, Tocharus J (2014) Protective effect of melatonin on methamphetamine-induced apoptosis in glioma cell line. Neurotox Res 25(3):286–294
32. Parameyong A, Charngkaew K, Govitrapong P, Chetsawang B (2013) Melatonin attenuates methamphetamine-induced disturbances in mitochondrial dynamics and degeneration in neuroblastoma SH-SY5Y cells. J Pineal Res 55(3):313–323
33. Permpoonputtana K, Govitrapong P (2013) The anti-inflammatory effect of melatonin on methamphetamine-induced proinflammatory mediators in human neuroblastoma dopamine SH-SY5Y cell lines. Neurotox Res 23(2):189–199
34. Mukda S, Vimolratana O, Govitrapong P (2011) Melatonin attenuates the amphetamine-induced decrease in vesicular monoamine transporter-2 expression in postnatal rat striatum. Neurosci Lett 488(2):154–157
35. Nopparat C, Porter JE, Ebadi M, Govitrapong P (2010) The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy. J Pineal Res 49(4):382–389
36. Suwanjang W, Phansuwan-Pujito P, Govitrapong P, Chetsawang B (2010) The protective effect of melatonin on methamphetamine-induced calpain-dependent death pathway in human neuroblastoma SH-SY5Y cultured cells. J Pineal Res 48(2):94–101
37. Kaewsuk S, Sae-ung K, Phansuwan-Pujito P, Govitrapong P (2009) Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain. Neurochem Int 55(6):397–405
38. Wisessmith W, Phansuwan-Pujito P, Govitrapong P, Chetsawang B (2009) Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells. J Pineal Res 46(4):433–440
39. Kongsuphol P, Mukda S, Nopparat C, Villarroel A, Govitrapong P (2009) Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells. J Pineal Res 46(2):199–206
40. Zhang M, An C, Gao Y, Leak RK, Chen J, Zhang F (2013) Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection. Prog Neurobiol 100:30–47
41. Granado N, Lastres-Becker I, Ares-Santos S, Oliva I, Martin E, Cuadrado A, Moratalla R (2011) Nrf2 deficiency potentiates methamphetamine-induced dopaminergic axonal damage and gliosis in the striatum. Glia 59(12):1850–1863
42. Turpaev KT (2013) Keap1-Nrf2 signaling pathway: mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles. Biochemistry 78(2):111–126
43. Jones SR, Gainetdinov RR, Wightman RM, Caron MG (1998) Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. J Neurosci 18(6):1979–1986
44. Huang YN, Wang JY, Lee CT, Lin CH, Lai CC, Wang JY (2012) L-ascorbate attenuates methamphetamine neurotoxicity through enhancing the induction of endogenous heme oxygenase-1. Toxicol Appl Pharmacol 265(2):241–252
45. Cadet JL, Ordonez SV, Ordonez JV (1997) Methamphetamine induces apoptosis in immortalized neural cells: protection by the proto-oncogene, bcl-2. Synapse 25(2):176–184
46. Winek CL, Wahba WW, Winek CL Jr, Balzer TW (2001) Drug and chemical blood-level data 2001. Forensic Sci Int 122(2–3):107–123
47. Pacchioni AM, Vallone J, Melendez RI, Shih A, Murphy TH, Kalivas PW (2007) Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity. Brain Res 5(1):26–35
48. Wang J, Hao H, Yao L, Zhang X, Zhao S, Ling EA, Hao A, Li G (2012) Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells. J Pineal Res 53(2):180–187
49. Das A, Belagodu A, Reiter RJ, Ray SK, Banik NL (2008) Cytoprotective effects of melatonin on C6 astroglial cells exposed to glutamate excitotoxicity and oxidative stress. J Pineal Res 45(2):117–124
50. Castro LM, Gallant M, Niles LP (2005) Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells. J Neurochem 95(5):1227–1236