Hypusination of eukaryotic initiation factor 5A via cAMP-PKA-ERK1/2 pathway is required for ligand-induced downregulation of LH receptor mRNA expression in the ovary

Molecular and Cellular Endocrinology

Volumn 413, Issue , 2015, Pages 90-95

  Gulappa, Thippeswamy ^a   Menon, Bindu ^a   Menon, K M J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

CAMP PKA ERK1 2; EIF5A; Hypusination; LH receptor; LRBP

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CHORIONIC GONADOTROPIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GC7; INITIATION FACTOR 5A; LUTEINIZING HORMONE RECEPTOR; LUTEINIZING HORMONE RECEPTOR MESSENGER RNA BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN INHIBITOR; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; HYPUSINE; INITIATION FACTOR; LRBP PROTEIN, RAT; LUTEINIZING HORMONE; LYSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DOWN REGULATION; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE EXPRESSION REGULATION; NONHUMAN; OVARY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN HYPUSINATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR DOWN REGULATION; TIME; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; GENE EXPRESSION REGULATION; LUTEINIZING HORMONE; LYSINE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 3; OVARY; PEPTIDE INITIATION FACTORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LH; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 84938197811     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.06.014     Document Type: Article

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