-
1
-
-
0022973967
-
Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization
-
Abbruzzese A, Park MH, Folk JE (1986) Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization. J Biol Chem 261: 3085-3089
-
(1986)
J Biol Chem
, vol.261
, pp. 3085-3089
-
-
Abbruzzese, A.1
Park, M.H.2
Folk, J.E.3
-
2
-
-
0026027968
-
The active site of deoxyhypusyl hydroxylase: Use of catechol peptides and their component chelator and peptide moieties as molecular probes
-
Abbruzzese A, Hanauske-Abel HM, Park MH, Henke S, Folk JE (1991) The active site of deoxyhypusyl hydroxylase: use of catechol peptides and their component chelator and peptide moieties as molecular probes. Biochim Biophys Acta 1077: 159-166
-
(1991)
Biochim Biophys Acta
, vol.1077
, pp. 159-166
-
-
Abbruzzese, A.1
Hanauske-Abel, H.M.2
Park, M.H.3
Henke, S.4
Folk, J.E.5
-
3
-
-
0027947377
-
Induced gene expression of the hypusine-containing protein eukaryotic initiation factor 5A in activated human T lymphocytes
-
Bevec D, Klier H, Holter W, Tschachler E, Valent P, Lottspeich F, Baumruker T, Hauber J (1994) Induced gene expression of the hypusine-containing protein eukaryotic initiation factor 5A in activated human T lymphocytes. Proc Natl Acad Sci USA 91: 10829-10833
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10829-10833
-
-
Bevec, D.1
Klier, H.2
Holter, W.3
Tschachler, E.4
Valent, P.5
Lottspeich, F.6
Baumruker, T.7
Hauber, J.8
-
4
-
-
0026446891
-
Cytostasis induced in L1210 murine leukemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor
-
Byers TL, Ganem B, Pegg AE (1992) Cytostasis induced in L1210 murine leukemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor, Biochem J 287: 717-724
-
(1992)
Biochem J
, vol.287
, pp. 717-724
-
-
Byers, T.L.1
Ganem, B.2
Pegg, A.E.3
-
5
-
-
0023882062
-
+ stimulated the spermidine-dependent hypusine formation on the 18-kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells
-
+ stimulated the spermidine-dependent hypusine formation on the 18-kDa protein in cytosolic lysates derived from NB-15 mouse neuroblastoma cells. FEBS Letters 229: 325-328
-
(1988)
FEBS Letters
, vol.229
, pp. 325-328
-
-
Chen, K.-Y.1
Dou, Q.-P.2
-
6
-
-
0020162215
-
Post-translational formation of hypusine in a single major protein occurs generally in growing cells and is associated with activation of lymphocyte growth
-
Cooper HL, Park MH, Folk JE (1982) Post-translational formation of hypusine in a single major protein occurs generally in growing cells and is associated with activation of lymphocyte growth. Cell 29: 791-797
-
(1982)
Cell
, vol.29
, pp. 791-797
-
-
Cooper, H.L.1
Park, M.H.2
Folk, J.E.3
-
8
-
-
0022998702
-
Changes in eIF-4D hypusine modification or abundance are not correlated with translational repression in HeLa cells
-
Duncan RF, Hershey JWB (1986) Changes in eIF-4D hypusine modification or abundance are not correlated with translational repression in HeLa cells. J Biol Chem 261: 12903-12906
-
(1986)
J Biol Chem
, vol.261
, pp. 12903-12906
-
-
Duncan, R.F.1
Hershey, J.W.B.2
-
10
-
-
0018414755
-
Dissociation of the early antiproliferative action of methylglyoxal bis(guanylhydrazone) from polyamine depletion. A comparison of the effects of DL-alpha-difluoromethyl ornithinine and methylglyoxal bis(guanylhydrazone) on the growth of human fibroblasts
-
Hölttä E, Pohjanpelto P, Jänne J (1979) Dissociation of the early antiproliferative action of methylglyoxal bis(guanylhydrazone) from polyamine depletion. A comparison of the effects of DL-alpha-difluoromethyl ornithinine and methylglyoxal bis(guanylhydrazone) on the growth of human fibroblasts. FEBS Lett 97: 9-14
-
(1979)
FEBS Lett
, vol.97
, pp. 9-14
-
-
Hölttä, E.1
Pohjanpelto, P.2
Jänne, J.3
-
11
-
-
0015698572
-
Hypusine, N6-(4-amino-2-hydroxybutyl)-2,6-diaminohexanoic acid, in tissue proteins of mammals
-
Imaoka N, Nakaijima T (1973) Hypusine, N6-(4-amino-2-hydroxybutyl)-2,6-diaminohexanoic acid, in tissue proteins of mammals. Biochim Biophys Acta 320: 97-103
-
(1973)
Biochim Biophys Acta
, vol.320
, pp. 97-103
-
-
Imaoka, N.1
Nakaijima, T.2
-
12
-
-
0027518126
-
Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies: Effective inhibition by bis- and mono-guanylated diamines and polyamines
-
Jakus J, Wolff EC, Park MH, Folk JE (1993) Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies: effective inhibition by bis- and mono-guanylated diamines and polyamines. J Biol Chem 268: 13151-13159
-
(1993)
J Biol Chem
, vol.268
, pp. 13151-13159
-
-
Jakus, J.1
Wolff, E.C.2
Park, M.H.3
Folk, J.E.4
-
13
-
-
0028072759
-
Structural features of the eIF-5A precursor required for posttranslational synthesis of deoxyhypusine
-
Joe YA, Park MH (1994) Structural features of the eIF-5A precursor required for posttranslational synthesis of deoxyhypusine. J Biol Chem 269: 25916-25921
-
(1994)
J Biol Chem
, vol.269
, pp. 25916-25921
-
-
Joe, Y.A.1
Park, M.H.2
-
14
-
-
0000134797
-
Cloning and expresssion of human deoxyhypusine synthase cDNA: Structure-function studies with the recombinant enzyme and mutant proteins
-
Joe YA, Wolff EC, Park MH (1995) Cloning and expresssion of human deoxyhypusine synthase cDNA: structure-function studies with the recombinant enzyme and mutant proteins. J Biol Chem 270: 22386-22392
-
(1995)
J Biol Chem
, vol.270
, pp. 22386-22392
-
-
Joe, Y.A.1
Wolff, E.C.2
Park, M.H.3
-
15
-
-
0028145708
-
Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae
-
Kang HA, Hershey JWB (1994) Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae. J Biol Chem 269: 3934-3940
-
(1994)
J Biol Chem
, vol.269
, pp. 3934-3940
-
-
Kang, H.A.1
Hershey, J.W.B.2
-
16
-
-
0029162976
-
Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase: Expression and characterization of the enzyme
-
Kang KR, Wolff EC, Park MH, Folk JE, Chung SI (1995) Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase: expression and characterization of the enzyme. J Biol Chem 270: 18408-18412
-
(1995)
J Biol Chem
, vol.270
, pp. 18408-18412
-
-
Kang, K.R.1
Wolff, E.C.2
Park, M.H.3
Folk, J.E.4
Chung, S.I.5
-
17
-
-
0017171975
-
Purification and properties of rabbit reticulocyte protein synthesis initiation factors M2Bα and M2Bβ
-
Kemper WM, Berry KW, Merrick WC (1976) Purification and properties of rabbit reticulocyte protein synthesis initiation factors M2Bα and M2Bβ. J Biol Chem 251: 5551-5557
-
(1976)
J Biol Chem
, vol.251
, pp. 5551-5557
-
-
Kemper, W.M.1
Berry, K.W.2
Merrick, W.C.3
-
18
-
-
0028922566
-
Purification and characterization of human deoxyhypusine synthase from HeLa cells
-
Klier H, Csonga R, Steinkasser A, Wöhl T, Lottspeich F, Eder J (1995) Purification and characterization of human deoxyhypusine synthase from HeLa cells. FEBS Lett 364: 207-210
-
(1995)
FEBS Lett
, vol.364
, pp. 207-210
-
-
Klier, H.1
Csonga, R.2
Steinkasser, A.3
Wöhl, T.4
Lottspeich, F.5
Eder, J.6
-
19
-
-
0029133121
-
Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: Synthesis and biological activity
-
Lee YB, Park MH, Folk JE (1995) Diamine and triamine analogs and derivatives as inhibitors of deoxyhypusine synthase: synthesis and biological activity. J Med Chem 38: 3053-3061
-
(1995)
J Med Chem
, vol.38
, pp. 3053-3061
-
-
Lee, Y.B.1
Park, M.H.2
Folk, J.E.3
-
20
-
-
9244220698
-
Inhibitors of hypusine biosynthesis: Potential anticancer agents
-
in press
-
Lee YB, Joe YA, Park MH (1996) Inhibitors of hypusine biosynthesis: potential anticancer agents. J Biomedical Res (in press)
-
(1996)
J Biomedical Res
-
-
Lee, Y.B.1
Joe, Y.A.2
Park, M.H.3
-
21
-
-
0023645825
-
Hypusine formation in protein by a two-step process in cell lysates
-
Murphey RJ, Gerner EW (1987) Hypusine formation in protein by a two-step process in cell lysates. J Biol Chem 262: 15033-15036
-
(1987)
J Biol Chem
, vol.262
, pp. 15033-15036
-
-
Murphey, R.J.1
Gerner, E.W.2
-
22
-
-
0015135776
-
6-(4-amino-2-hydroxybutyl)-2,6-diaminohexanoic acid, in mammalian organs
-
6-(4-amino-2-hydroxybutyl)-2,6-diaminohexanoic acid, in mammalian organs. Biochim Biophys Acta 252: 92-97
-
(1971)
Biochim Biophys Acta
, vol.252
, pp. 92-97
-
-
Nakajima, T.1
Matsubayashi, T.2
Kakimoto, Y.3
Sano, I.4
-
23
-
-
0024817833
-
Nomenclature of initiation, elongation and termination factors for translation in eukaryotes. Recommendations 1988
-
NC-IUB [Nomenclature Committee, IUB], Safer B (1989) Nomenclature of initiation, elongation and termination factors for translation in eukaryotes. Recommendations 1988. Eur J Biochem 186: 1-3
-
(1989)
Eur J Biochem
, vol.186
, pp. 1-3
-
-
Safer, B.1
-
24
-
-
0023656029
-
Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides
-
Park MH (1987) Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides. J Biol Chem 262: 12730-12734
-
(1987)
J Biol Chem
, vol.262
, pp. 12730-12734
-
-
Park, M.H.1
-
25
-
-
0024418120
-
The essential role of hypusine in eukaryotic translation initiation factor 4D (eIF-4D). Purification of eIF-4D and its precursors and comparison of their activities
-
Park MH (1989) The essential role of hypusine in eukaryotic translation initiation factor 4D (eIF-4D). Purification of eIF-4D and its precursors and comparison of their activities. J Biol Chem 264: 18531-18535
-
(1989)
J Biol Chem
, vol.264
, pp. 18531-18535
-
-
Park, M.H.1
-
26
-
-
0022998793
-
Biosynthetic labeling of hypusine in mammalian cells. Carbon-hydrogen bond fissions revealed by dual labeling
-
Park MH, Folk JE (1986) Biosynthetic labeling of hypusine in mammalian cells. Carbon-hydrogen bond fissions revealed by dual labeling. J Biol Chem 261: 14108-14111
-
(1986)
J Biol Chem
, vol.261
, pp. 14108-14111
-
-
Park, M.H.1
Folk, J.E.2
-
27
-
-
0019570951
-
Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor
-
Park MH, Cooper HL, Folk JE (1981) Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor. Proc Natl Acad Sci USA 78: 2869-2873
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 2869-2873
-
-
Park, M.H.1
Cooper, H.L.2
Folk, J.E.3
-
29
-
-
0021759446
-
The mammalian hypusine-containing protein, eukaryotic initiation factor 4D. Stuctural homology of this protein from several species
-
Park MH, Chung SI, Cooper HL, Folk JE (1984a) The mammalian hypusine-containing protein, eukaryotic initiation factor 4D. Stuctural homology of this protein from several species. J Biol Chem 259: 4563-4565
-
(1984)
J Biol Chem
, vol.259
, pp. 4563-4565
-
-
Park, M.H.1
Chung, S.I.2
Cooper, H.L.3
Folk, J.E.4
-
30
-
-
0021136831
-
ε-(4-amino-2-hydroxybutyl)lysine]. Alignment of the butylamine segment and source of the secondary amino nitrogen
-
ε-(4-amino-2-hydroxybutyl)lysine]. Alignment of the butylamine segment and source of the secondary amino nitrogen. J Biol Chem 259: 12123-12127
-
(1984)
J Biol Chem
, vol.259
, pp. 12123-12127
-
-
Park, M.H.1
Liberato, D.J.2
Yergey, A.L.3
Folk, J.E.4
-
31
-
-
0025824235
-
Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine
-
Park MH, Wolff EC, Smit-McBride Z, Hershey JWB, Folk JE (1991) Comparison of the activities of variant forms of eIF-4D. The requirement for hypusine or deoxyhypusine. J Biol Chem 266: 7988-7994
-
(1991)
J Biol Chem
, vol.266
, pp. 7988-7994
-
-
Park, M.H.1
Wolff, E.C.2
Smit-McBride, Z.3
Hershey, J.W.B.4
Folk, J.E.5
-
32
-
-
0027197906
-
Hypusine: Its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation
-
Park MH, Wolff EC, Folk JE (1993a) Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation. BioFactors 4: 95-104
-
(1993)
BioFactors
, vol.4
, pp. 95-104
-
-
Park, M.H.1
Wolff, E.C.2
Folk, J.E.3
-
33
-
-
0027370986
-
Is hypusine essential for eukaryotic cell proliferation?
-
Park MH, Wolff EC, Folk JE (1993b) Is hypusine essential for eukaryotic cell proliferation? Trends Biochem Sci 18: 475-479
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 475-479
-
-
Park, M.H.1
Wolff, E.C.2
Folk, J.E.3
-
34
-
-
0027944561
-
Antiproliferative effects of inhibitors of deoxyhypusine synthase: Inhibition of growth of CHO cells by guanyl diaminess
-
Park MH, Wolff EC, Lee YB, Folk JE (1994) Antiproliferative effects of inhibitors of deoxyhypusine synthase: inhibition of growth of CHO cells by guanyl diaminess. J Biol Chem 269: 27827-27832
-
(1994)
J Biol Chem
, vol.269
, pp. 27827-27832
-
-
Park, M.H.1
Wolff, E.C.2
Lee, Y.B.3
Folk, J.E.4
-
35
-
-
0021353298
-
Hydralazine inhibition of the posttranslational hydroxylation of deoxyhypusine, a polyamine-derived amino acid
-
Paz MA, Torrelio BM, Gallop PM (1984) Hydralazine inhibition of the posttranslational hydroxylation of deoxyhypusine, a polyamine-derived amino acid. Biochem Pharmacol 33: 779-785
-
(1984)
Biochem Pharmacol
, vol.33
, pp. 779-785
-
-
Paz, M.A.1
Torrelio, B.M.2
Gallop, P.M.3
-
36
-
-
0023881236
-
Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy
-
Pegg AE (1988) Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. Cancer Res 48: 759-774
-
(1988)
Cancer Res
, vol.48
, pp. 759-774
-
-
Pegg, A.E.1
-
37
-
-
0027767592
-
Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation
-
Ruhl M, Himmelspach M, Bahr GM, Hammerschmid F, Jaksche H, Wolff B, Aschauer H, Farrington GK, Probst H, Bevec D, Hauber J (1993) Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation. J Cell Biol 123: 1309-1320
-
(1993)
J Cell Biol
, vol.123
, pp. 1309-1320
-
-
Ruhl, M.1
Himmelspach, M.2
Bahr, G.M.3
Hammerschmid, F.4
Jaksche, H.5
Wolff, B.6
Aschauer, H.7
Farrington, G.K.8
Probst, H.9
Bevec, D.10
Hauber, J.11
-
38
-
-
0022468147
-
Isolation and identification of 2-(γ-aminobutyryl) hypusine
-
Sano A, Kotani K, Kakimoto Y (1986) Isolation and identification of 2-(γ-aminobutyryl) hypusine. J Neurochem 46: 1046-1049
-
(1986)
J Neurochem
, vol.46
, pp. 1046-1049
-
-
Sano, A.1
Kotani, K.2
Kakimoto, Y.3
-
39
-
-
0025810272
-
Translation initiation factor 5A and its hypusine modification are essential for cell viability in yeast
-
Schnier J, Schwelberger H, Smit-McBride Z, Kang HA, Hershey JWB (1991) Translation initiation factor 5A and its hypusine modification are essential for cell viability in yeast. Mol Cell Biol 11: 3105-3114
-
(1991)
Mol Cell Biol
, vol.11
, pp. 3105-3114
-
-
Schnier, J.1
Schwelberger, H.2
Smit-McBride, Z.3
Kang, H.A.4
Hershey, J.W.B.5
-
40
-
-
0017701040
-
Initiation of mammalian protein synthesis. Purification and characterization of seven initiation factors
-
Schreier MH, Erni B, Staehelin T (1977) Initiation of mammalian protein synthesis. Purification and characterization of seven initiation factors. J Mol Biol 116: 727-753
-
(1977)
J Mol Biol
, vol.116
, pp. 727-753
-
-
Schreier, M.H.1
Erni, B.2
Staehelin, T.3
-
41
-
-
0006282285
-
Archaebacterial protein contains hypusine, a unique amino acid characteristic for eukaryotic translation initiation factor 4D
-
Schümann H, Klink F (1989) Archaebacterial protein contains hypusine, a unique amino acid characteristic for eukaryotic translation initiation factor 4D. System Appl Microbiol 11: 103-107
-
(1989)
System Appl Microbiol
, vol.11
, pp. 103-107
-
-
Schümann, H.1
Klink, F.2
-
42
-
-
0015235461
-
Hypusine, a new amino acid occuring in bovine brain. Isolation and structural determination
-
Shiba T, Mizote H, Kaneko T, Nakajima T, Kakimoto Y, Sano I (1971) Hypusine, a new amino acid occuring in bovine brain. Isolation and structural determination. Biochim Biophys Acta 244: 523-531
-
(1971)
Biochim Biophys Acta
, vol.244
, pp. 523-531
-
-
Shiba, T.1
Mizote, H.2
Kaneko, T.3
Nakajima, T.4
Kakimoto, Y.5
Sano, I.6
-
43
-
-
0010431036
-
Synthesis and stereochemistry of hypusine, a new amino acid
-
Shiba T, Akiyama H, Umeda I, Okada S, Wakamiya T (1982) Synthesis and stereochemistry of hypusine, a new amino acid. Bull Chem Soc Jpn 55: 899-903
-
(1982)
Bull Chem Soc Jpn
, vol.55
, pp. 899-903
-
-
Shiba, T.1
Akiyama, H.2
Umeda, I.3
Okada, S.4
Wakamiya, T.5
-
44
-
-
0024509495
-
Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein
-
Smit-McBride Z, Dever TE, Hershey JWB, Merrick WC (1989) Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein. J Biol Chem 264: 1578-1583
-
(1989)
J Biol Chem
, vol.264
, pp. 1578-1583
-
-
Smit-McBride, Z.1
Dever, T.E.2
Hershey, J.W.B.3
Merrick, W.C.4
-
45
-
-
0024428107
-
Protein synthesis initiation factor eIF-4D. Functional comparison of native and unhypusinated forms of the protein
-
Smit-McBride Z, Schnier J, Kaufman RJ, Hershey JWB (1989) Protein synthesis initiation factor eIF-4D. Functional comparison of native and unhypusinated forms of the protein. J Biol Chem 264: 18527-18530
-
(1989)
J Biol Chem
, vol.264
, pp. 18527-18530
-
-
Smit-McBride, Z.1
Schnier, J.2
Kaufman, R.J.3
Hershey, J.W.B.4
-
47
-
-
0028859315
-
Purification of deoxyhypusine synthase from Neurospora crassa to homogeneity by substrate elution affinity chromatography
-
Tao Y, Chen KY (1995) Purification of deoxyhypusine synthase from Neurospora crassa to homogeneity by substrate elution affinity chromatography. J Biol Chem 270: 383-386
-
(1995)
J Biol Chem
, vol.270
, pp. 383-386
-
-
Tao, Y.1
Chen, K.Y.2
-
48
-
-
0026030639
-
Isolation and identification of 2-(β-alanyl)hypusine from bovine brain
-
Ueno S, Kotani K, Sano A, Kakimoto Y (1991) Isolation and identification of 2-(β-alanyl)hypusine from bovine brain. Biochim Biophys Acta 1073: 233-235
-
(1991)
Biochim Biophys Acta
, vol.1073
, pp. 233-235
-
-
Ueno, S.1
Kotani, K.2
Sano, A.3
Kakimoto, Y.4
-
49
-
-
0027485617
-
The HYP2 gene of Saccharomyces cerevisiae is essential for aerobic growth: Characterization of different isoforms of the hypusine-containing protein Hyp2p and analysis of gene disruption mutants
-
Wöhl T, Klier H, Ammer H, Lottspeich F, Magdolen V (1993) The HYP2 gene of Saccharomyces cerevisiae is essential for aerobic growth: characterization of different isoforms of the hypusine-containing protein Hyp2p and analysis of gene disruption mutants. Mol Gen Genet 241: 305-311
-
(1993)
Mol Gen Genet
, vol.241
, pp. 305-311
-
-
Wöhl, T.1
Klier, H.2
Ammer, H.3
Lottspeich, F.4
Magdolen, V.5
-
51
-
-
0028965712
-
Deoxyhypusine synthase from rat testis: Purification and characterization
-
Wolff EC, Lee YB, Chung SI, Folk JE, Park MH (1995) Deoxyhypusine synthase from rat testis: purification and characterization. J Biol Chem 270: 8660-8666
-
(1995)
J Biol Chem
, vol.270
, pp. 8660-8666
-
-
Wolff, E.C.1
Lee, Y.B.2
Chung, S.I.3
Folk, J.E.4
Park, M.H.5
|