Down-regulation of rac GTPase-activating protein OCRL1 causes aberrant activation of rac1 in osteoarthritis development

Arthritis and Rheumatology

Volumn 67, Issue 8, 2015, Pages 2154-2163

  Zhu, Shouan ^a   Dai, Jun ^a   Liu, Huanhuan ^a   Cong, Xiaoxia ^a   Chen, Yishan ^a   Wu, Yan ^a   Hu, Hu ^a   Heng, Boon Chin ^b   Ouyang, Hong Wei ^b   Zhou, Yiting ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGENASE 3; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INTERLEUKIN 1BETA; LENTIVIRUS VECTOR; RAC PROTEIN; RAC1 PROTEIN; MESSENGER RNA; NEUROPEPTIDE; OCRL PROTEIN, HUMAN; OCRL PROTEIN, MOUSE; PHOSPHATASE; RAC1 PROTEIN, HUMAN; RAC1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CHONDROCYTE HYPERTROPHY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERTROPHY; KNEE MENISCUS; MINERALIZATION; MOUSE; NONHUMAN; OSTEOARTHRITIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE STUDY; ANIMAL; ARTICULAR CARTILAGE; DISEASE MODEL; GENE VECTOR; GENETICS; HINDLIMB; IN VITRO STUDY; KNEE OSTEOARTHRITIS; LENTIVIRINAE; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURGERY;

ANIMALS; CARTILAGE, ARTICULAR; CHONDROCYTES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENETIC VECTORS; GTPASE-ACTIVATING PROTEINS; HUMANS; HYPERTROPHY; IN VITRO TECHNIQUES; LENTIVIRUS; MICE; NEUROPEPTIDES; OSTEOARTHRITIS, KNEE; PHOSPHORIC MONOESTER HYDROLASES; RAC1 GTP-BINDING PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STIFLE;

EID: 84938152423     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39174     Document Type: Article

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