Update on Estimation of Kidney Function in Diabetic Kidney Disease

Current Diabetes Reports

Volumn 15, Issue 9, 2015, Pages

  Bjornstad, Petter ^a   Cherney, David Z ^b   Maahs, David M ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Albuminuria; Creatinine; Cystatin C; Diabetic kidney disease; Glomerular filtration rate; Impaired GFR; Iohexol; Rapid GFR decline; Renal hyperfiltration

Indexed keywords

ALLOPURINOL; BETA TRACE PROTEIN; BIOLOGICAL MARKER; CREATININE; CYSTATIN C; EDETATE CHROMIUM CR 51; EMPAGLIFLOZIN; GLUCOSE; INULIN; IOHEXOL; IOTALAMIC ACID; PENTETATE TECHNETIUM TC 99M; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; UNCLASSIFIED DRUG;

ACUTE HYPERGLYCEMIA; ALBUMINURIA; ARTICLE; BOLD SIGNAL; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DISEASE SEVERITY; DRIED CAPILLARY BLOOD SPOT; END STAGE RENAL DISEASE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HEMATOLOGICAL PROCEDURE; HIGH RISK POPULATION; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY CLEARANCE; KIDNEY FUNCTION; KIDNEY FUNCTION TEST; MEASUREMENT ACCURACY; NUCLEAR MAGNETIC RESONANCE IMAGING; PEDIATRICS; PHENOTYPE; RENAL HYPERFILTRATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REPRODUCIBILITY; BLOOD; CHEMISTRY; KIDNEY; PATHOPHYSIOLOGY; URINE;

BIOMARKERS; CREATININE; CYSTATIN C; DIABETIC NEPHROPATHIES; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY;

EID: 84938074774     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-015-0633-2     Document Type: Article

References (110)

1. Padala S, Tighiouart H, Inker LA, Contreras G, Beck GJ, Lewis J, et al. Accuracy of a GFR estimating equation over time in people with a wide range of kidney function. Am J Kidney Dis. 2012;60(2):217–24.
2. Isakova T, Craven TE, Lee J, Scialla JJ, Xie H, Wahl P, et al. Fibroblast growth factor 23 and incident CKD in type 2 diabetes. Clin J Am Soc Nephrol. 2015;10(1):29–38.
3. Chiang JL, Kirkman MS, Laffel LM, Peters AL. Type 1 diabetes through the life span: a position statement of the American Diabetes Association. Diabetes Care. 2014;37(7):2034–54.
4. Professional Practice Committee for the Standards of Medical Care in Diabetes-2015. Diabetes Care. 2015;38(1):S88–9. The most recent recommendations from American Diabetes Association which include annual GFR evaluation in adolescents with diabetes.
5. Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012;367(1):20–9.
6. de Boer IH, Sun W, Cleary PA, Lachin JM, Molitch ME, Zinman B, et al. Longitudinal changes in estimated and measured GFR in type 1 diabetes. Clin J Am Soc Nephrol. 2014;25(4):810–8.
7. de Boer IH. Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study. Diabetes Care. 2014;37(1):24–30.
8. Jerums G, Premaratne E, Panagiotopoulos S, MacIsaac RJ. The clinical significance of hyperfiltration in diabetes. Diabetologia. 2010;53(10):2093–104.
9. Sasson AN, Cherney DZ. Renal hyperfiltration related to diabetes mellitus and obesity in human disease. J Diabetes. 2012;3(1):1–6.
10. Bjornstad P, Cherney D, Maahs DM. Early diabetic nephropathy in type 1 diabetes: new insights. Curr Opin Endocrinol Diabetes Obes. 2014;21(4):279–86.
11. Collins AJ, Foley RN, Herzog C, Chavers B, Gilbertson D, Ishani A, et al. US Renal Data System 2010 annual data report. Am J Kidney Dis. 2011;57 Suppl 1, A8, e1–526.
12. Maahs DM, Rewers M. Editorial: mortality and renal disease in type 1 diabetes mellitus—progress made, more to be done. J Clin Endocrinol Metab. 2006;91(10):3757–9.
13. Orchard TJ, Secrest AM, Miller RG, Costacou T. In the absence of renal disease, 20 year mortality risk in type 1 diabetes is comparable to that of the general population: a report from the Pittsburgh Epidemiology of Diabetes Complications Study. Diabetologia. 2010;53(11):2312–9.
14. Collins AJ, Foley RN, Chavers B, Gilbertson D, Herzog C, Johansen K, et al. United States Renal Data System 2011 Annual Data Report: Atlas of chronic kidney disease & end-stage renal disease in the United States. Am J Kidney Dis. 2012;59 Suppl 1, A7, e1-420.
15. Borch-Johnsen K, Kreiner S. Proteinuria: value as predictor of cardiovascular mortality in insulin dependent diabetes mellitus. Br Med J (Clin Res Ed). 1987;294(6588):1651–4.
16. Orchard TJ, Olson JC, Erbey JR, Williams K, Forrest KY, Smithline Kinder L, et al. Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10-year follow-up data from the Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes Care. 2003;26(5):1374–9.
17. Maahs DM, Jalal D, Chonchol M, Johnson RJ, Rewers M, Snell-Bergeon JK. Impaired renal function further increases odds of 6-year coronary artery calcification progression in adults with type 1 diabetes: the CACTI study. Diabetes Care. 2013;36(9):2607–14.
18. International evaluation of cause-specific mortality and IDDM. Diabetes Epidemiology Research International Mortality Study Group. Diabetes Care. 1991;14(1):55–60.
19. Twyman S, Rowe D, Mansell P, Schapira D, Betts P, Leatherdale B. Longitudinal study of urinary albumin excretion in young diabetic patients—Wessex Diabetic Nephropathy Project. Diabet Med. 2001;18(5):402–8.
20. Gross JL, de Azevedo MJ, Silveiro SP, Canani LH, Caramori ML, Zelmanovitz T. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care. 2005;28(1):164–76.
21. Perkins BA, Ficociello LH, Silva KH, Finkelstein DM, Warram JH, Krolewski AS. Regression of microalbuminuria in type 1 diabetes. N Engl J Med. 2003;348(23):2285–93. This study demonstrates regression of microalbuminuria to normoalbuminuria in type 1 diabetes.
22. Molitch ME, Steffes M, Sun W, Rutledge B, Cleary P, de Boer IH, et al. Development and progression of renal insufficiency with and without albuminuria in adults with type 1 diabetes in the diabetes control and complications trial and the epidemiology of diabetes interventions and complications study. Diabetes Care. 2010;33(7):1536–43.
23. Maahs D, Jalal D, Chonchol M, Johnson R, Rewers M, Snell-Bergeon JK. Impaired renal function further increases odds of 6 year coronary artery calcification progression in adults with type 1 diabetes: The CACTI Study. Diabetes Care (in review). 2013.
24. Bjornstad P, Maahs D, Wadwa P, Pyle L, Rewers M, Eckel R, et al. Plasma triglycerides predict incident albuminuria and progression of coronary artery calcification in adults with type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes Study. J Clin Lipidol. 2014.
25. Magee GM, Bilous RW, Cardwell CR, Hunter SJ, Kee F, Fogarty DG. Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis. Diabetologia. 2009;52(4):691–7.
26. Maahs DM, Ogden LG, Kretowski A, Snell-Bergeon JK, Kinney GL, Berl T, et al. Serum cystatin C predicts progression of subclinical coronary atherosclerosis in individuals with type 1 diabetes. Diabetes. 2007;56(11):2774–9.
27. Shlipak MG, Matsushita K, Arnlov J, Inker LA, Katz R, Polkinghorne KR, et al. Cystatin C versus creatinine in determining risk based on kidney function. N Engl J Med. 2013;369(10):932–43.
28. Bjornstad P, Maahs DM, Rivard CJ, Pyle L, Rewers M, Johnson RJ, et al. Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol. 2014.
29. Krolewski AS, Niewczas MA, Skupien J, Gohda T, Smiles A, Eckfeldt JH, et al. Early progressive renal decline precedes the onset of microalbuminuria and its progression to macroalbuminuria. Diabetes Care. 2014;37(1):226–34. This study provides evidence that rapid GFR decline may precede the onset of microalbuminuria in type 1 diabetes.
30. Bjornstad P, Cherney DZI, Snell-Bergeon J, Pyle L, Rewers M, Johnson RJ, et al. Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with type 1 diabetes. Nephrol Dial Transplant. 2015. This study demonstrates associations between renal hyperfiltration, rapid GFR decline and impaired GFR in adults with type 1 diabetes.
31. Standards of medical care in diabetes—2013. Diabetes Care. 2013;36 Suppl 1:S11-66. Epub 2013/01/04.
32. KDOQI. Clinical practice guidelines and clinical practice recommendations for diabetes and chronic kidney disease. Am J Kidney Dis. 2007;49(2 Suppl 2):S12–S154.
33. Stevens PE, Levin A. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med. 2013;158(11):825–30.
34. Rehling M, Moller ML, Thamdrup B, Lund JO, Trap-Jensen J. Simultaneous measurement of renal clearance and plasma clearance of 99mTc-labelled diethylenetriaminepenta-acetate, 51Cr-labelled ethylenediaminetetra-acetate and inulin in man. Clin Sci (Lond). 1984;66(5):613–9.
35. Medeiros FS, Sapienza MT, Prado ES, Agena F, Shimizu MH, Lemos FB, et al. Validation of plasma clearance of 51Cr-EDTA in adult renal transplant recipients: comparison with inulin renal clearance. Transpl Int. 2009;22(3):323–31.
36. Hernandez Ocampo J, Torres Rosales A, Rodriguez Castellanos F. [Comparison of four methods for measuring glomerular filtration rate by inulin clearance in healthy individuals and patients with renal failure. Nefrologia. 2010;30(3):324–30. Comparacion de cuatro metodos de medicion de la tasa de filtracion glomerular con depuracion de inulina en individuos sanos y en pacientes con insuficiencia renal.
37. Odlind B, Hallgren R, Sohtell M, Lindstrom B. Is 125I iothalamate an ideal marker for glomerular filtration? Kidney Int. 1985;27(1):9–16.
38. Berg UB, Back R, Celsi G, Halling SE, Homberg I, Krmar RT, et al. Comparison of plasma clearance of iohexol and urinary clearance of inulin for measurement of GFR in children. Am J Kidney Dis. 2011;57(1):55–61.
39. Stevens LA, Levey AS. Measured GFR as a confirmatory test for estimated GFR. Clin J Am Soc Nephrol. 2009;20(11):2305–13.
40. Clorius JH, Dreikorn K, Zelt J, Raptou E, Weber D, Rubinstein K, et al. Renal graft evaluation with pertechnetate and I-131 hippuran. A comparative clinical study. J Nucl Med. 1979;20(10):1029–37.
41. Wilkinson J, Fleming JS, Waller DG. Effect of food and activity on the reproducibility of isotopic GFR estimation. Nucl Med Commun. 1990;11(10):697–700.
42. Merrill AJ, Cargill WH, Borders MA, Cavin E. The effect of exercise on the renal plasma flow and filtration rate of normal and cardiac subjects. J Clin Invest. 1948;27(2):272–7.
43. Bhathena DB, Bullock WE, Nuttall CE, Luke RG. The effects of amphotericin B therapy on the intrarenal vasculature and renal tubules in man. A study of biopsies by light, electron and immunofluorescence microscopy. Clin Nephrol. 1978;9(3):103–10.
44. Cherney DZ, Scholey JW, Sochett E, Bradley TJ, Reich HN. The acute effect of clamped hyperglycemia on the urinary excretion of inflammatory cytokines/chemokines in uncomplicated type 1 diabetes: a pilot study. Diabetes Care. 2011;34(1):177–80.
45. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med. 1999;130(6):461–70.
46. Rule AD, Larson TS, Bergstralh EJ, Slezak JM, Jacobsen SJ, Cosio FG. Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med. 2004;141(12):929–37.
47. Tan GD, Lewis AV, James TJ, Altmann P, Taylor RP, Levy JC. Clinical usefulness of cystatin C for the estimation of glomerular filtration rate in type 1 diabetes: reproducibility and accuracy compared with standard measures and iohexol clearance. Diabetes Care. 2002;25(11):2004–9.
48. Perkins BA, Nelson RG, Ostrander BE, Blouch KL, Krolewski AS, Myers BD, et al. Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration: results of a 4-year follow-up study. Clin J Am Soc Nephrol. 2005;16(5):1404–12.
49. Beauvieux MC, Le Moigne F, Lasseur C, Raffaitin C, Perlemoine C, Barthe N, et al. New predictive equations improve monitoring of kidney function in patients with diabetes. Diabetes Care. 2007;30(8):1988–94.
50. Macisaac RJ, Tsalamandris C, Thomas MC, Premaratne E, Panagiotopoulos S, Smith TJ, et al. Estimating glomerular filtration rate in diabetes: a comparison of cystatin-C- and creatinine-based methods. Diabetologia. 2006;49(7):1686–9.
51. Stevens LA, Schmid CH, Greene T, Zhang YL, Beck GJ, Froissart M, et al. Comparative performance of the CKD Epidemiology Collaboration (CKD-EPI) and the Modification of Diet in Renal Disease (MDRD) study equations for estimating GFR levels above 60 mL/min/1.73 m2. Am J Kidney Dis. 2010;56(3):486–95.
52. Grubb A, Horio M, Hansson LO, Bjork J, Nyman U, Flodin M, et al. Generation of a new cystatin C-based estimating equation for glomerular filtration rate by use of 7 assays standardized to the international calibrator. Clin Chem. 2014;60(7):974–86.
53. Stevens LA, Coresh J, Schmid CH, Feldman HI, Froissart M, Kusek J, et al. Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis. 2008;51(3):395–406.
54. Cattozzo G, Guerra E, Ceriotti F, Franzini C. Commutable calibrator with value assigned by the IFCC reference procedure to harmonize serum lactate dehydrogenase activity results measured by 2 different methods. Clin Chem. 2008;54(8):1349–55.
55. Ceriotti F, Boyd JC, Klein G, Henny J, Queralto J, Kairisto V, et al. Reference intervals for serum creatinine concentrations: assessment of available data for global application. Clin Chem. 2008;54(3):559–66.
56. Blirup-Jensen S, Grubb A, Lindstrom V, Schmidt C, Althaus H. Standardization of cystatin C: development of primary and secondary reference preparations. Scand J Clin Lab Investig Suppl. 2008;241:67–70.
57. Grubb A, Blirup-Jensen S, Lindstrom V, Schmidt C, Althaus H, Zegers I. First certified reference material for cystatin C in human serum ERM-DA471/IFCC. Clin Chem Lab Med. 2010;48(11):1619–21.
58. Shlipak MG, Katz R, Kestenbaum B, Fried LF, Newman AB, Siscovick DS, et al. Rate of kidney function decline in older adults: a comparison using creatinine and cystatin C. Am J Nephrol. 2009;30(3):171–8.
59. Cherney DZ, Sochett EB, Dekker MG, Perkins BA. Ability of cystatin C to detect acute changes in glomerular filtration rate provoked by hyperglycaemia in uncomplicated type 1 diabetes. Diabetic medicine: a journal of the British Diabetic Association. 2010;27(12):1358–65.
60. Knight EL, Verhave JC, Spiegelman D, Hillege HL, de Zeeuw D, Curhan GC, et al. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int. 2004;65(4):1416–21.
61. Bjornstad P, Maahs DM, Cherney DZ, Cree-Green M, West A, Pyle L, et al. Insulin sensitivity is an important determinant of renal health in adolescents with type 2 diabetes. Diabetes Care. 2014.
62. Bjornstad P, Snell-Bergeon JK, Rewers M, Jalal D, Chonchol MB, Johnson RJ, et al. Early diabetic nephropathy: a complication of reduced insulin sensitivity in type 1 diabetes. Diabetes Care. 2013.
63. Huang SH, Sharma AP, Yasin A, Lindsay RM, Clark WF, Filler G. Hyperfiltration affects accuracy of creatinine eGFR measurement. Clin J Am Soc Nephrol. 2011;6(2):274–80.
64. Premaratne E, MacIsaac RJ, Finch S, Panagiotopoulos S, Ekinci E, Jerums G. Serial measurements of cystatin C are more accurate than creatinine-based methods in detecting declining renal function in type 1 diabetes. Diabetes Care. 2008;31(5):971–3.
65. Shlipak MG, Katz R, Kestenbaum B, Siscovick D, Fried L, Newman A, et al. Rapid decline of kidney function increases cardiovascular risk in the elderly. Clin J Am Soc Nephrol. 2009;20(12):2625–30.
66. Krolewski AS, Warram JH, Forsblom C, Smiles AM, Thorn L, Skupien J, et al. Serum concentration of cystatin C and risk of end-stage renal disease in diabetes. Diabetes Care. 2012;35(11):2311–6.
67. Skupien J, Warram JH, Groop PH, Krolewski AS. Cystatin-based estimated GFR versus creatinine-based and creatinine- and cystatin-based estimated GFR for ESRD and mortality risk in diabetes. Am J Kidney Dis. 2013;62(1):184–6.
68. Maahs DM, Jalal D, McFann K, Rewers M, Snell-Bergeon JK. Systematic shifts in cystatin C between 2006 and 2010. Clin J Am Soc Nephrol. 2011;6(8):1952–5.
69. Maahs DM, Prentice N, McFann K, Snell-Bergeon JK, Jalal D, Bishop FK, et al. Age and sex influence cystatin C in adolescents with and without type 1 diabetes. Diabetes Care. 2011;34(11):2360–2.
70. Rognant N, Lemoine S, Laville M, Hadj-Aissa A, Dubourg L. Performance of the chronic kidney disease epidemiology collaboration equation to estimate glomerular filtration rate in diabetic patients. Diabetes Care. 2011;34(6):1320–2.
71. Bjornstad P, McQueen RB, Snell-Bergeon JK, Cherney D, Pyle L, Perkins B, et al. Fasting blood glucose—a missing variable for GFR-estimation in type 1 diabetes? PLoS One. 2014;9(4), e96264.
72. Maahs DM. Early detection of kidney disease in type 1 diabetes: what do we really know? Diabetes Technol Ther. 2012;14(7):541–4.
73. Filler G, Yasin A, Medeiros M. Methods of assessing renal function. Pediatr Nephrol. 2014;29(2):183–92.
74. Schwartz GJ, Work DF. Measurement and estimation of GFR in children and adolescents. Clin J Am Soc Nephrol. 2009;4(11):1832–43.
75. Schwartz GJ, Munoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, et al. New equations to estimate GFR in children with CKD. Clin J Am Soc Nephrol. 2009;20(3):629–37.
76. Schwartz GJ, Haycock GB, Edelmann Jr CM, Spitzer A. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics. 1976;58(2):259–63.
77. Sharma AP, Yasin A, Garg AX, Filler G. Diagnostic accuracy of cystatin C-based eGFR equations at different GFR levels in children. Clin J Am Soc Nephrol. 2011;6(7):1599–608. This study evaluates the diagnostic accuracy of eGFR equations at different GFR levels in children and adolescents.
78. Berg UB, Nyman U, Back R, Hansson M, Monemi KA, Herthelius M, et al. New standardized cystatin C and creatinine GFR equations in children validated with inulin clearance. Pediatr Nephrol. 2015. This study describes promising new GFR equations in children and adolescents with standardized cystatin C and creatinine.
79. Bouvet Y, Bouissou F, Coulais Y, Seronie-Vivien S, Tafani M, Decramer S, et al. GFR is better estimated by considering both serum cystatin C and creatinine levels. Pediatr Nephrol. 2006;21(9):1299–306.
80. Schwartz GJ, Schneider MF, Maier PS, Moxey-Mims M, Dharnidharka VR, Warady BA, et al. Improved equations estimating GFR in children with chronic kidney disease using an immunonephelometric determination of cystatin C. Kidney Int. 2012;82(4):445–53.
81. Christiansen JS, Frandsen M, Parving HH. Effect of intravenous glucose infusion on renal function in normal man and in insulin-dependent diabetics. Diabetologia. 1981;21(4):368–73.
82. Dullaart RP, Meijer S, Sluiter WJ, Doorenbos H. Renal haemodynamic changes in response to moderate hyperglycaemia in type 1 (insulin-dependent) diabetes mellitus. Eur J Clin Investig. 1990;20(2):208–13.
83. Wiseman MJ, Mangili R, Alberetto M, Keen H, Viberti G. Glomerular response mechanisms to glycemic changes in insulin-dependent diabetics. Kidney Int. 1987;31(4):1012–8.
84. Wiseman MJ, Saunders AJ, Keen H, Viberti G. Effect of blood glucose control on increased glomerular filtration rate and kidney size in insulin-dependent diabetes. N Engl J Med. 1985;312(10):617–21.
85. Miller JA. Impact of hyperglycemia on the renin angiotensin system in early human type 1 diabetes mellitus. Clin J Am Soc Nephrol. 1999;10(8):1778–85.
86. Miller JA, Floras JS, Zinman B, Skorecki KL, Logan AG. Effect of hyperglycaemia on arterial pressure, plasma renin activity and renal function in early diabetes. Clin Sci (Lond). 1996;90(3):189–95.
87. Cherney DZ, Reich HN, Scholey JW, Daneman D, Mahmud FH, Har RL, et al. The effect of aliskiren on urinary cytokine/chemokine responses to clamped hyperglycaemia in type 1 diabetes. Diabetologia. 2013;56(10):2308–17.
88. Cherney DZ, Perkins BA, Soleymanlou N, Maione M, Lai V, Lee A, et al. The renal hemodynamic effect of SGLT2 inhibition in patients with type 1 diabetes. Circulation. 2013. This study demonstrates the renal hemodynamic effects of SGLT2 inhibitors in adults with type 1 diabetes.
89. Amin R, Turner C, van Aken S, Bahu TK, Watts A, Lindsell DR, et al. The relationship between microalbuminuria and glomerular filtration rate in young type 1 diabetic subjects: The Oxford Regional Prospective Study. Kidney Int. 2005;68(4):1740–9.
90. Dahlquist G, Stattin EL, Rudberg S. Urinary albumin excretion rate and glomerular filtration rate in the prediction of diabetic nephropathy; a long-term follow-up study of childhood onset type-1 diabetic patients. Nephrol Dial Transplant. 2001;16(7):1382–6.
91. Caramori ML, Gross JL, Pecis M, de Azevedo MJ. Glomerular filtration rate, urinary albumin excretion rate, and blood pressure changes in normoalbuminuric normotensive type 1 diabetic patients: an 8-year follow-up study. Diabetes Care. 1999;22(9):1512–6.
92. Cherney D, Maahs DM. Cystatin C versus creatinine for kidney function-based risk. N Engl J Med. 2013;369(25):2458.
93. Stevens LA, Coresh J, Greene T, Levey AS. Assessing kidney function—measured and estimated glomerular filtration rate. N Engl J Med. 2006;354(23):2473–83.
94. Filler G, Priem F, Lepage N, Sinha P, Vollmer I, Clark H, et al. Beta-trace protein, cystatin C, beta(2)-microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children. Clin Chem. 2002;48(5):729–36.
95. Benlamri A, Nadarajah R, Yasin A, Lepage N, Sharma AP, Filler G. Development of a beta-trace protein based formula for estimation of glomerular filtration rate. Pediatr Nephrol. 2010;25(3):485–90.
96. Inoue T, Kozawa E, Okada H, Inukai K, Watanabe S, Kikuta T, et al. Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging. Clin J Am Soc Nephrol. 2011;22(8):1429–34.
97. Harrington MG, Aebersold R, Martin BM, Merril CR, Hood L. Identification of a brain-specific human cerebrospinal fluid glycoprotein, beta-trace protein. Appl Theor Electrophor. 1993;3(5):229–34.
98. White CA, Akbari A, Doucette S, Fergusson D, Hussain N, Dinh L, et al. Estimating GFR using serum beta trace protein: accuracy and validation in kidney transplant and pediatric populations. Kidney Int. 2009;76(7):784–91.
99. Akbari A, Lepage N, Keely E, Clark HD, Jaffey J, MacKinnon M, et al. Cystatin-C and beta trace protein as markers of renal function in pregnancy. BJOG. 2005;112(5):575–8.
100. Witzel SH, Huang SH, Braam B, Filler G. Estimation of GFR using beta-trace protein in children. Clin J Am Soc Nephrol. 2015;10(3):401–9.
101. Michaely HJ, Metzger L, Haneder S, Hansmann J, Schoenberg SO, Attenberger UI. Renal BOLD-MRI does not reflect renal function in chronic kidney disease. Kidney Int. 2012;81(7):684–9.
102. Niculescu-Duvaz I, D’Mello L, Maan Z, Barron JL, Newman DJ, Dockrell ME, et al. Development of an outpatient finger-prick glomerular filtration rate procedure suitable for epidemiological studies. Kidney Int. 2006;69(7):1272–5.
103. Mafham MM, Niculescu-Duvaz I, Barron J, Emberson JR, Dockrell ME, Landray MJ, et al. A practical method of measuring glomerular filtration rate by iohexol clearance using dried capillary blood spots. Nephron Clin Pract. 2007;106(3):c104–12.
104. Maahs DM, Bushman L, Kerr B, Ellis SL, Pyle L, McFann K, et al. A practical method to measure GFR in people with type 1 diabetes. J Diabetes Complicat. 2014;28(5):667–73.
105. Bjornstad P, Anderson PL, Maahs DM. Measuring glomerular filtration rate by iohexol clearance on filter paper is feasible in adolescents with type 1 diabetes in the ambulatory setting. Acta Diabetol. 2015.
106. Margolick JB, Jacobson LP, Schwartz GJ, Abraham AG, Darilay AT, Kingsley LA, et al. Factors affecting glomerular filtration rate, as measured by iohexol disappearance, in men with or at risk for HIV infection. PLoS One. 2014;9(2), e86311.
107. Pambianco G, Costacou T, Ellis D, Becker DJ, Klein R, Orchard TJ. The 30-year natural history of type 1 diabetes complications: the Pittsburgh Epidemiology of Diabetes Complications Study experience. Diabetes. 2006;55(5):1463–9.
108. Wood JR, Miller KM, Maahs DM, Beck RW, Dimeglio LA, Libman IM, et al. Most youth with type 1 diabetes in the T1D Exchange Clinic Registry do not meet American Diabetes Association or International Society for Pediatric and Adolescent Diabetes Clinical Guidelines. Diabetes Care. 2013;36(7):2035–7.
109. Skrtic M, Cherney DZ. Sodium-glucose cotransporter-2 inhibition and the potential for renal protection in diabetic nephropathy. Curr Opin Nephrol Hypertens. 2015;24(1):96–103.
110. Maahs DM, Caramori L, Cherney DZ, Galecki AT, Gao C, Jalal D, et al. Uric acid lowering to prevent kidney function loss in diabetes: The Preventing Early Renal Function Loss (PERL) Allopurinol Study. Curr Diab Rep. 2013.