-
1
-
-
84866479608
-
Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model
-
Van Giezen J.J., Sidaway J., Glaves P., et al. Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model. J Cardiovasc Pharmacol Ther 2012, 17:164-172.
-
(2012)
J Cardiovasc Pharmacol Ther
, vol.17
, pp. 164-172
-
-
Van Giezen, J.J.1
Sidaway, J.2
Glaves, P.3
-
2
-
-
84894420031
-
Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1
-
Armstrong D., Summers C., Ewart L., et al. Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1. J Cardiovasc Pharmacol Ther 2014, 19:209-219.
-
(2014)
J Cardiovasc Pharmacol Ther
, vol.19
, pp. 209-219
-
-
Armstrong, D.1
Summers, C.2
Ewart, L.3
-
3
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin L., Becker R.C., Budaj A., et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009, 361:1045-1057.
-
(2009)
N Engl J Med
, vol.361
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
-
4
-
-
73949112820
-
Randomized double-blind assessment of the ONSET and OFFSet of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study
-
Gurbel P.A., Bliden K.P., Butler K., et al. Randomized double-blind assessment of the ONSET and OFFSet of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study. Circulation 2009, 120:2577-2585.
-
(2009)
Circulation
, vol.120
, pp. 2577-2585
-
-
Gurbel, P.A.1
Bliden, K.P.2
Butler, K.3
-
5
-
-
77958003916
-
Inhibitory effects of ticagrelor compared to clopidogrel on platelet function in patients with acute coronary syndromes: the PLATO PLATELET substudy
-
Storey R.F., Angiolillo D., Patil S., et al. Inhibitory effects of ticagrelor compared to clopidogrel on platelet function in patients with acute coronary syndromes: the PLATO PLATELET substudy. J Am Coll Cardiol 2010, 56:1456-1462.
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 1456-1462
-
-
Storey, R.F.1
Angiolillo, D.2
Patil, S.3
-
6
-
-
84895522368
-
Ticagrelor increases adenosine plasma concentration in patients with an acute coronary syndrome
-
Bonello L., Laine M., Kipson N., et al. Ticagrelor increases adenosine plasma concentration in patients with an acute coronary syndrome. J Am Coll Cardiol 2014, 63:872-877.
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 872-877
-
-
Bonello, L.1
Laine, M.2
Kipson, N.3
-
7
-
-
84873712137
-
Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans
-
Wittfeldt A., Emanuelsson H., Brandrup-Wognsen G., et al. Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans. J Am Coll Cardiol 2013, 61:723-727.
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 723-727
-
-
Wittfeldt, A.1
Emanuelsson, H.2
Brandrup-Wognsen, G.3
-
8
-
-
84884497073
-
Differential effect of ticagrelor versus prasugrel on coronary blood flow velocity in patients with non-ST-elevation acute coronary syndrome undergoing percutaneous coronary intervention: an exploratory study
-
Alexopoulos D., Moulias A., Koutsogiannis N., et al. Differential effect of ticagrelor versus prasugrel on coronary blood flow velocity in patients with non-ST-elevation acute coronary syndrome undergoing percutaneous coronary intervention: an exploratory study. Circ Cardiovasc Interv 2013, 6:277-283.
-
(2013)
Circ Cardiovasc Interv
, vol.6
, pp. 277-283
-
-
Alexopoulos, D.1
Moulias, A.2
Koutsogiannis, N.3
-
9
-
-
84906936926
-
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect
-
Nanhwan M.K., Ling S., Kodakandla M., et al. Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect. Arterioscler Thromb Vasc Biol 2014, 34:2078-2085.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 2078-2085
-
-
Nanhwan, M.K.1
Ling, S.2
Kodakandla, M.3
-
10
-
-
84876228478
-
Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism
-
Nylander S., Femia E.A., Scavone M., et al. Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism. J Thromb Haemost 2013, 11:1867-1876.
-
(2013)
J Thromb Haemost
, vol.11
, pp. 1867-1876
-
-
Nylander, S.1
Femia, E.A.2
Scavone, M.3
-
11
-
-
84912021475
-
Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study
-
Storey R.F., James S.K., Siegbahn A., et al. Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study. Platelets 2013, 25:517-525.
-
(2013)
Platelets
, vol.25
, pp. 517-525
-
-
Storey, R.F.1
James, S.K.2
Siegbahn, A.3
-
12
-
-
84867582405
-
Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery
-
Varenhorst C., Alström U., Scirica B.M., et al. Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery. J Am Coll Cardiol 2012, 60:1623-1630.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 1623-1630
-
-
Varenhorst, C.1
Alström, U.2
Scirica, B.M.3
-
13
-
-
84908253107
-
Causes of mortality with ticagrelor compared with clopidogrel in acute coronary syndromes
-
Varenhorst C., Alström U., Braun O.Ö., et al. Causes of mortality with ticagrelor compared with clopidogrel in acute coronary syndromes. Heart 2014, 100:1762-1769.
-
(2014)
Heart
, vol.100
, pp. 1762-1769
-
-
Varenhorst, C.1
Alström, U.2
Braun, O.Ö.3
-
16
-
-
1242272722
-
The equilibrative nucleoside transporter family, SLC29
-
Baldwin S., Beal P., Yao S.M., et al. The equilibrative nucleoside transporter family, SLC29. Pflugers Arch - Eur J Physiol 2004, 447:735-743.
-
(2004)
Pflugers Arch - Eur J Physiol
, vol.447
, pp. 735-743
-
-
Baldwin, S.1
Beal, P.2
Yao, S.M.3
-
17
-
-
0022637702
-
Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity
-
Gresele P., Arnout J., Deckmyn H., et al. Mechanism of the antiplatelet action of dipyridamole in whole blood: modulation of adenosine concentration and activity. Thromb Haemost 1986, 55:12-18.
-
(1986)
Thromb Haemost
, vol.55
, pp. 12-18
-
-
Gresele, P.1
Arnout, J.2
Deckmyn, H.3
-
18
-
-
38749090163
-
Nitric oxide regulates neutrophil migration through microparticle formation
-
Nolan S., Dixon R., Norman K., et al. Nitric oxide regulates neutrophil migration through microparticle formation. Am J Pathol 2008, 172:265-273.
-
(2008)
Am J Pathol
, vol.172
, pp. 265-273
-
-
Nolan, S.1
Dixon, R.2
Norman, K.3
-
19
-
-
0031590746
-
Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate
-
Kawa S., Kimura S., Hakomori S., et al. Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate. FEBS Lett 1997, 420:196-200.
-
(1997)
FEBS Lett
, vol.420
, pp. 196-200
-
-
Kawa, S.1
Kimura, S.2
Hakomori, S.3
-
20
-
-
0042388118
-
Critical role of galectin-3 in phagocytosis by macrophages
-
Sano H., Hsu D.K., Apgar J.R., et al. Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest 2003, 112:389-397.
-
(2003)
J Clin Invest
, vol.112
, pp. 389-397
-
-
Sano, H.1
Hsu, D.K.2
Apgar, J.R.3
-
21
-
-
0023232975
-
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) - a selective high-affinity antagonist radioligand for A1 adenosine receptors
-
Lohse M.J., Klotz K.N., Lindenbornfotinos J., et al. 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) - a selective high-affinity antagonist radioligand for A1 adenosine receptors. Naunyn-Schmiedebergs Arch Pharmacol 1987, 336:204-210.
-
(1987)
Naunyn-Schmiedebergs Arch Pharmacol
, vol.336
, pp. 204-210
-
-
Lohse, M.J.1
Klotz, K.N.2
Lindenbornfotinos, J.3
-
22
-
-
0030075741
-
The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist
-
Zocchi C., Ongini E., Conti A., et al. The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist. J Pharmacol Exp Ther 1996, 276:398-404.
-
(1996)
J Pharmacol Exp Ther
, vol.276
, pp. 398-404
-
-
Zocchi, C.1
Ongini, E.2
Conti, A.3
-
23
-
-
33644770260
-
Adenosine receptors as therapeutic targets
-
Jacobson K.A., Gao Z.-G. Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 2006, 5:247-264.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 247-264
-
-
Jacobson, K.A.1
Gao, Z.-G.2
-
24
-
-
0031843837
-
Rapid fluorescence-based measurement of neutrophil migration in vitro
-
Frevert C.W., Wong V.A., Goodman R.B., et al. Rapid fluorescence-based measurement of neutrophil migration in vitro. J Immunol Methods 1998, 213:41-52.
-
(1998)
J Immunol Methods
, vol.213
, pp. 41-52
-
-
Frevert, C.W.1
Wong, V.A.2
Goodman, R.B.3
-
25
-
-
0026507232
-
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
-
Cronstein B.N., Levin R.I., Philips M., et al. Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol 1992, 148:2201-2206.
-
(1992)
J Immunol
, vol.148
, pp. 2201-2206
-
-
Cronstein, B.N.1
Levin, R.I.2
Philips, M.3
-
26
-
-
33845708770
-
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors
-
Chen Y., Corriden R., Inoue Y., et al. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 2006, 314:1792-1795.
-
(2006)
Science
, vol.314
, pp. 1792-1795
-
-
Chen, Y.1
Corriden, R.2
Inoue, Y.3
-
27
-
-
85017801882
-
Dipyridamole enhances inhibitory effect of adenosine on neutrophils in human peripheral blood
-
Zhang Y., Zhang Q., Zhang J., et al. Dipyridamole enhances inhibitory effect of adenosine on neutrophils in human peripheral blood. J Nanjing Med Univ 2008, 22:243-245.
-
(2008)
J Nanjing Med Univ
, vol.22
, pp. 243-245
-
-
Zhang, Y.1
Zhang, Q.2
Zhang, J.3
-
28
-
-
77957943307
-
Intravascular danger signals guide neutrophils to sites of sterile inflammation
-
McDonald B., Pittman K., Menezes G.B., et al. Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 2010, 330:362-366.
-
(2010)
Science
, vol.330
, pp. 362-366
-
-
McDonald, B.1
Pittman, K.2
Menezes, G.B.3
-
29
-
-
0027983055
-
Adenosine, an endogenous anti-inflammatory agent
-
Cronstein B.N. Adenosine, an endogenous anti-inflammatory agent. J Appl Physiol 1994, 76:5-13.
-
(1994)
J Appl Physiol
, vol.76
, pp. 5-13
-
-
Cronstein, B.N.1
-
30
-
-
52149098412
-
A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis
-
Inoue Y., Chen Y., Hirsh M.I., et al. A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis. Shock 2008, 30:173-177.
-
(2008)
Shock
, vol.30
, pp. 173-177
-
-
Inoue, Y.1
Chen, Y.2
Hirsh, M.I.3
-
31
-
-
50449094182
-
Activation of the A3 adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils
-
van der Hoeven D., Wan T.C., Auchampach J.A. Activation of the A3 adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils. Mol Pharmacol 2008, 74:685-696.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 685-696
-
-
van der Hoeven, D.1
Wan, T.C.2
Auchampach, J.A.3
-
32
-
-
84876689863
-
Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury
-
Mulloy D.P., Sharma A.K., Fernandez L.G., et al. Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury. Ann Thorac Surg 2013, 95:1762-1767.
-
(2013)
Ann Thorac Surg
, vol.95
, pp. 1762-1767
-
-
Mulloy, D.P.1
Sharma, A.K.2
Fernandez, L.G.3
-
33
-
-
0025135242
-
Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory
-
Salmon J.E., Cronstein B.N. Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory. J Immunol 1990, 145:2235-2240.
-
(1990)
J Immunol
, vol.145
, pp. 2235-2240
-
-
Salmon, J.E.1
Cronstein, B.N.2
-
34
-
-
0028283812
-
The role of cyclic AMP, calcium and filamentous actin in adenosine modulation of Fc receptor-mediated phagocytosis in human neutrophils
-
Zalavary S., Stendahl O., Bengtsson T. The role of cyclic AMP, calcium and filamentous actin in adenosine modulation of Fc receptor-mediated phagocytosis in human neutrophils. Biochim Biophys Acta 1994, 1222:249-256.
-
(1994)
Biochim Biophys Acta
, vol.1222
, pp. 249-256
-
-
Zalavary, S.1
Stendahl, O.2
Bengtsson, T.3
-
35
-
-
0033038246
-
Inhibition by dipyridamole of neutrophil adhesion to vascular endothelium during coronary bypass surgery
-
Chello M., Mastroroberto P., Malta E., et al. Inhibition by dipyridamole of neutrophil adhesion to vascular endothelium during coronary bypass surgery. Ann Thorac Surg 1999, 67:1277-1282.
-
(1999)
Ann Thorac Surg
, vol.67
, pp. 1277-1282
-
-
Chello, M.1
Mastroroberto, P.2
Malta, E.3
-
36
-
-
84857444798
-
Ticagrelor induces adenosine triphosphate release from human red blood cells
-
Öhman J., Kudira R., Albinsson S., et al. Ticagrelor induces adenosine triphosphate release from human red blood cells. Biochem Biophys Res Commun 2012, 418:754-758.
-
(2012)
Biochem Biophys Res Commun
, vol.418
, pp. 754-758
-
-
Öhman, J.1
Kudira, R.2
Albinsson, S.3
-
39
-
-
77956204462
-
A2B adenosine receptors protect against sepsis-induced mortality by dampening excessive inflammation
-
Csoka B., Nemeth Z.H., Rosenberger P., et al. A2B adenosine receptors protect against sepsis-induced mortality by dampening excessive inflammation. J Immunol 2010, 185:542-550.
-
(2010)
J Immunol
, vol.185
, pp. 542-550
-
-
Csoka, B.1
Nemeth, Z.H.2
Rosenberger, P.3
|