메뉴 건너뛰기




Volumn 8, Issue 5, 2015, Pages 5642-5649

Prognostic and predictive values of Nrf2, Keap1, p16 and E-cadherin expression in ovarian epithelial carcinoma

Author keywords

E Cadherin; Keap1; Nrf2; Ovarian cancer; P16

Indexed keywords

CADHERIN; CDH1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; KEAP1 PROTEIN, HUMAN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NFE2L2 PROTEIN, HUMAN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NRF2; TUMOR MARKER;

EID: 84937910008     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (44)

References (33)
  • 2
    • 84864359086 scopus 로고    scopus 로고
    • Mechanism of chemical activation of Nrf2
    • Li Y, Paonessa JD and Zhang Y. Mechanism of chemical activation of Nrf2. PLos One 2012; 7: e 35122.
    • (2012) PLos One , vol.7
    • Li, Y.1    Paonessa, J.D.2    Zhang, Y.3
  • 4
    • 77958125017 scopus 로고    scopus 로고
    • Discovery of the negative regulator of Nrf2, Keap1: a historical overview
    • Itoh K, Mimura J and Yamamoto M. Discovery of the negative regulator of Nrf2, Keap1: a historical overview. Antioxid Redox Signal 2010; 13: 1665-78.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1665-1678
    • Itoh, K.1    Mimura, J.2    Yamamoto, M.3
  • 6
    • 78751703950 scopus 로고    scopus 로고
    • Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
    • Taguchi K, Motohashi H and Yamamoto M. Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 2011; 16: 123-40.
    • (2011) Genes Cells , vol.16 , pp. 123-140
    • Taguchi, K.1    Motohashi, H.2    Yamamoto, M.3
  • 7
    • 79953236274 scopus 로고    scopus 로고
    • Molecular cross-talk between the Nrf2/ Keap1 signaling pathway, autophagy, and apoptosis
    • Stepkowski TM and Kruszewski MK. Molecular cross-talk between the Nrf2/ Keap1 signaling pathway, autophagy, and apoptosis. Free Radic Biol Med 2011; 50: 1186-95.
    • (2011) Free Radic Biol Med , vol.50 , pp. 1186-1195
    • Stepkowski, T.M.1    Kruszewski, M.K.2
  • 8
    • 0034657319 scopus 로고    scopus 로고
    • Cadherin superfamily genes: functions, genomic organization, and neurologic diversity
    • Yagi T and Takeichi M. Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes Dev 2000; 14: 1169-80.
    • (2000) Genes Dev , vol.14 , pp. 1169-1180
    • Yagi, T.1    Takeichi, M.2
  • 9
    • 0036901407 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and dissociation of occluding-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress
    • Rao RK, Basuroy S, Rao VU, Karnaky KJ, Jr and Gupta A. Tyrosine phosphorylation and dissociation of occluding-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative stress. Biochem J 2002; 368: 471-81.
    • (2002) Biochem J , vol.368 , pp. 471-481
    • Rao, R.K.1    Basuroy, S.2    Rao, V.U.3    Karnaky, K.J.4    Gupta, A.5
  • 11
    • 84864392890 scopus 로고    scopus 로고
    • Abnormal expression of E-cadherin in tumor cells is associated with poor prognosis in gastric carcinoma
    • Li Y, Chen CQ, He YL, Cai SR, Yang DJ, He WL, Xu JB and Zan WH. Abnormal expression of E-cadherin in tumor cells is associated with poor prognosis in gastric carcinoma. J Surg Oncol 2012; 106: 304-10.
    • (2012) J Surg Oncol , vol.106 , pp. 304-310
    • Li, Y.1    Chen, C.Q.2    He, Y.L.3    Cai, S.R.4    Yang, D.J.5    He, W.L.6    Xu, J.B.7    Zan, W.H.8
  • 13
    • 84861389705 scopus 로고    scopus 로고
    • E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells
    • Kim WD, Kim YW, Cho IJ, Lee CH and Kim SG. E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells. J Cell Sci 2012; 125: 1284-95.
    • (2012) J Cell Sci , vol.125 , pp. 1284-1295
    • Kim, W.D.1    Kim, Y.W.2    Cho, I.J.3    Lee, C.H.4    Kim, S.G.5
  • 15
    • 84867202926 scopus 로고    scopus 로고
    • Mutational and expressional analyses of Nrf2 and Keap1 in sarcomas
    • Je EM, An CH, Yoo NJ and Lee SH. Mutational and expressional analyses of Nrf2 and Keap1 in sarcomas. Tumori 2012; 98: 540-5.
    • (2012) Tumori , vol.98 , pp. 540-545
    • Je, E.M.1    An, C.H.2    Yoo, N.J.3    Lee, S.H.4
  • 17
    • 84858158377 scopus 로고    scopus 로고
    • Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer
    • Merikallio H, Pääkkö P, Kinnula VL, Harju T and Soini Y. Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer. Hum Pathol 2012; 43: 577-84.
    • (2012) Hum Pathol , vol.43 , pp. 577-584
    • Merikallio, H.1    Pääkkö, P.2    Kinnula, V.L.3    Harju, T.4    Soini, Y.5
  • 18
    • 53049105119 scopus 로고    scopus 로고
    • Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer
    • Shibata Y, Kokubu A, Gotoh M, Ojima H, Ohta T, Yamamoto M and Hirohashi S. Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer. Gastroenterology 2008; 135: 1358-1368.
    • (2008) Gastroenterology , vol.135 , pp. 1358-1368
    • Shibata, Y.1    Kokubu, A.2    Gotoh, M.3    Ojima, H.4    Ohta, T.5    Yamamoto, M.6    Hirohashi, S.7
  • 21
    • 77954351631 scopus 로고    scopus 로고
    • High levels of Nrf2 determine chemoresistance in type II endometrial cancer
    • Jiang T, Chen N, Zhao F, Wang XJ, Kong B, Zheng W, and Zhang DD. High levels of Nrf2 determine chemoresistance in type II endometrial cancer. Cancer Res 2010; 70: 5486-96.
    • (2010) Cancer Res , vol.70 , pp. 5486-5496
    • Jiang, T.1    Chen, N.2    Zhao, F.3    Wang, X.J.4    Kong, B.5    Zheng, W.6    Zhang, D.D.7
  • 25
    • 84860708221 scopus 로고    scopus 로고
    • NRF2 is overexpressed in ovarian epithelial carcinoma and is regulated by gonadotrophin and sex-steroid hormones
    • Liao H, Zhou Q, Zhang Z, Wang Q, Sun Y, Yi X, Feng Y. NRF2 is overexpressed in ovarian epithelial carcinoma and is regulated by gonadotrophin and sex-steroid hormones. Oncol Rep 2012; 27: 1918-24.
    • (2012) Oncol Rep , vol.27 , pp. 1918-1924
    • Liao, H.1    Zhou, Q.2    Zhang, Z.3    Wang, Q.4    Sun, Y.5    Yi, X.6    Feng, Y.7
  • 26
    • 84874730539 scopus 로고    scopus 로고
    • Reactive oxygen species regulate FSH-induced expression of vascular endothelial growth factor via Nrf2 and HIF1a signaling in human epithelial ovarian cancer
    • Zhang Z, Wang Q, Ma J, Yi X, Zhu Y, Xi X, Feng Y, Jin Z. Reactive oxygen species regulate FSH-induced expression of vascular endothelial growth factor via Nrf2 and HIF1a signaling in human epithelial ovarian cancer. Oncol Rep 2013; 29: 1429-34.
    • (2013) Oncol Rep , vol.29 , pp. 1429-1434
    • Zhang, Z.1    Wang, Q.2    Ma, J.3    Yi, X.4    Zhu, Y.5    Xi, X.6    Feng, Y.7    Jin, Z.8
  • 28
    • 84857465771 scopus 로고    scopus 로고
    • Association of Keap1 and Nrf2 generic mutations and polymorphisms with endometrioid endometrial adenocarcinoma survival
    • Wong TF, Yoshinaga K, Monma Y, Ito K, Niikura H, Nagase S, Yamamoto M and Yaegashi N. Association of Keap1 and Nrf2 generic mutations and polymorphisms with endometrioid endometrial adenocarcinoma survival. Int J Gynecol Cancer 2011; 21: 1428-35.
    • (2011) Int J Gynecol Cancer , vol.21 , pp. 1428-1435
    • Wong, T.F.1    Yoshinaga, K.2    Monma, Y.3    Ito, K.4    Niikura, H.5    Nagase, S.6    Yamamoto, M.7    Yaegashi, N.8
  • 30
    • 34247551305 scopus 로고    scopus 로고
    • High-grade ovarian serous carcinoma exhibits significantly higher p16 expression than low-grade serous carcinoma and serous borderline tumour
    • O'Neill CJ, McBride HA, Connolly LE, Deavers MT, Malpica A and McCluggage WG. High-grade ovarian serous carcinoma exhibits significantly higher p16 expression than low-grade serous carcinoma and serous borderline tumour. Histopathology 2007; 50: 773-779.
    • (2007) Histopathology , vol.50 , pp. 773-779
    • O'Neill, C.J.1    McBride, H.A.2    Connolly, L.E.3    Deavers, M.T.4    Malpica, A.5    McCluggage, W.G.6
  • 31
  • 33
    • 84914665532 scopus 로고    scopus 로고
    • BRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumors
    • Zeppernick F, Ardighieri L, Hannibal CG, Vang R, Junge J, Kjaer SK, Zhang R, Kurman RJ, Shih IeM. BRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumors. Am J Surg Pathol 2014; 38: 1603-11.
    • (2014) Am J Surg Pathol , vol.38 , pp. 1603-1611
    • Zeppernick, F.1    Ardighieri, L.2    Hannibal, C.G.3    Vang, R.4    Junge, J.5    Kjaer, S.K.6    Zhang, R.7    Kurman, R.J.8    Shih, I.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.