메뉴 건너뛰기




Volumn 7, Issue 4, 2014, Pages 1502-1513

Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma

Author keywords

Autophagy; Chemoresistance; Cisplatin; Nrf2; Ovarian carcinoma

Indexed keywords

3-METHYLADENINE; ADENINE; ANTINEOPLASTIC AGENT; ATG12 PROTEIN, HUMAN; ATG3 PROTEIN, HUMAN; CISPLATIN; HEME OXYGENASE 1; HMOX1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; P62 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); RNA BINDING PROTEIN; SUMO PROTEIN; TRANSCRIPTION FACTOR NRF2; TUMOR MARKER; UBIQUITIN CONJUGATING ENZYME;

EID: 84899510313     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (113)

References (37)
  • 1
    • 0345256652 scopus 로고    scopus 로고
    • Cisplatin: mode of cytotoxic action and molecular basis of resistance
    • Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003; 22: 7265-79.
    • (2003) Oncogene , vol.22 , pp. 7265-7279
    • Siddik, Z.H.1
  • 3
    • 84885944468 scopus 로고    scopus 로고
    • The emerging role of the Nrf2-Keap1 signaling pathway in cancer
    • Jaramillo MC, Zhang DD. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev 2013; 27: 2179-91.
    • (2013) Genes Dev , vol.27 , pp. 2179-2191
    • Jaramillo, M.C.1    Zhang, D.D.2
  • 4
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999; 13: 76-86.
    • (1999) Genes Dev , vol.13 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6    Yamamoto, M.7
  • 5
    • 33344469643 scopus 로고    scopus 로고
    • Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
    • Kobayashi A, Kang MI, Watai Y, Tong KI, Shibata T, Uchida K, Yamamoto M. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol 2006; 26: 221-9.
    • (2006) Mol Cell Biol , vol.26 , pp. 221-229
    • Kobayashi, A.1    Kang, M.I.2    Watai, Y.3    Tong, K.I.4    Shibata, T.5    Uchida, K.6    Yamamoto, M.7
  • 7
    • 2342514015 scopus 로고    scopus 로고
    • An important role of Nrf2-ARE pathway in the cellular defense mechanism
    • Lee JM, Johnson JA. An important role of Nrf2-ARE pathway in the cellular defense mechanism. J Biochem Mol Biol 2004; 37: 139-43.
    • (2004) J Biochem Mol Biol , vol.37 , pp. 139-143
    • Lee, J.M.1    Johnson, J.A.2
  • 8
    • 79954416526 scopus 로고    scopus 로고
    • The cytoprotective role of the Keap1-Nrf2 pathway
    • Baird L, Dinkova-Kostova AT. The cytoprotective role of the Keap1-Nrf2 pathway. Arch Toxicol 2011; 85: 241-72.
    • (2011) Arch Toxicol , vol.85 , pp. 241-272
    • Baird, L.1    Dinkova-Kostova, A.T.2
  • 10
    • 76649089973 scopus 로고    scopus 로고
    • Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth
    • Zhang P, Singh A, Yegnasubramanian S, Esopi D, Kombairaju P, Bodas M, Wu H, Bova SG, Biswal S. Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. Mol Cancer Ther 2010; 9: 336-46.
    • (2010) Mol Cancer Ther , vol.9 , pp. 336-346
    • Zhang, P.1    Singh, A.2    Yegnasubramanian, S.3    Esopi, D.4    Kombairaju, P.5    Bodas, M.6    Wu, H.7    Bova, S.G.8    Biswal, S.9
  • 11
    • 77954351631 scopus 로고    scopus 로고
    • High levels of Nrf2 determine chemoresistance in type II endometrial cancer
    • Jiang T, Chen N, Zhao F, Wang XJ, Kong B, Zheng W, Zhang DD. High levels of Nrf2 determine chemoresistance in type II endometrial cancer. Cancer Res 2010; 70: 5486-96.
    • (2010) Cancer Res , vol.70 , pp. 5486-5496
    • Jiang, T.1    Chen, N.2    Zhao, F.3    Wang, X.J.4    Kong, B.5    Zheng, W.6    Zhang, D.D.7
  • 12
    • 67650922529 scopus 로고    scopus 로고
    • Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells
    • Akhdar H, Loyer P, Rauch C, Corlu A, Guillouzo A, Morel F. Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells. Eur J Cancer 2009; 45: 2219-27.
    • (2009) Eur J Cancer , vol.45 , pp. 2219-2227
    • Akhdar, H.1    Loyer, P.2    Rauch, C.3    Corlu, A.4    Guillouzo, A.5    Morel, F.6
  • 13
    • 84875251503 scopus 로고    scopus 로고
    • The role of autophagy in liver cancer: molecular mechanisms and potential therapeutic targets
    • Cui J, Gong Z, Shen HM. The role of autophagy in liver cancer: molecular mechanisms and potential therapeutic targets. Biochim Biophys Acta 2013; 1836: 15-26.
    • (2013) Biochim Biophys Acta , vol.1836 , pp. 15-26
    • Cui, J.1    Gong, Z.2    Shen, H.M.3
  • 14
    • 0035286734 scopus 로고    scopus 로고
    • Molecular dissection of autophagy: two ubiquitin-like systems
    • Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2001; 2: 211-6.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 211-216
    • Ohsumi, Y.1
  • 15
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451: 1069-75.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 16
    • 79955676537 scopus 로고    scopus 로고
    • Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
    • O'Donovan TR, O'Sullivan GC, McKenna SL. Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 2011; 7: 509-24.
    • (2011) Autophagy , vol.7 , pp. 509-524
    • O'Donovan, T.R.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 17
    • 77953763757 scopus 로고    scopus 로고
    • Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis
    • Choi CH, Jung YK, Oh SH. Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis. Mol Pharmacol 2010; 78: 114-25.
    • (2010) Mol Pharmacol , vol.78 , pp. 114-125
    • Choi, C.H.1    Jung, Y.K.2    Oh, S.H.3
  • 18
    • 84863985893 scopus 로고    scopus 로고
    • Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells
    • Sirichanchuen B, Pengsuparp T, Chanvorachote P. Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells. Mol Cell Biochem 2012; 364: 11-8.
    • (2012) Mol Cell Biochem , vol.364 , pp. 11-18
    • Sirichanchuen, B.1    Pengsuparp, T.2    Chanvorachote, P.3
  • 20
    • 77953366801 scopus 로고    scopus 로고
    • A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62
    • Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol 2010; 30: 3275-85.
    • (2010) Mol Cell Biol , vol.30 , pp. 3275-3285
    • Lau, A.1    Wang, X.J.2    Zhao, F.3    Villeneuve, N.F.4    Wu, T.5    Jiang, T.6    Sun, Z.7    White, E.8    Zhang, D.D.9
  • 22
    • 70350620150 scopus 로고    scopus 로고
    • Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway
    • Shim GS, Manandhar S, Shin DH, Kim TH, Kwak MK. Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway. Free Radic Biol Med 2009; 47: 1619-31.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1619-1631
    • Shim, G.S.1    Manandhar, S.2    Shin, D.H.3    Kim, T.H.4    Kwak, M.K.5
  • 23
    • 38149003106 scopus 로고    scopus 로고
    • Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: implication to cancer cell resistance
    • Cho JM, Manandhar S, Lee HR, Park HM, Kwak MK. Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: implication to cancer cell resistance. Cancer Lett 2008; 260: 96-108.
    • (2008) Cancer Lett , vol.260 , pp. 96-108
    • Cho, J.M.1    Manandhar, S.2    Lee, H.R.3    Park, H.M.4    Kwak, M.K.5
  • 26
    • 79953236274 scopus 로고    scopus 로고
    • Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis
    • Stepkowski TM, Kruszewski MK. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis. Free Radic Biol Med 2011; 50: 1186-95.
    • (2011) Free Radic Biol Med , vol.50 , pp. 1186-1195
    • Stepkowski, T.M.1    Kruszewski, M.K.2
  • 29
    • 79958789611 scopus 로고    scopus 로고
    • p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins
    • Yu H, Su J, Xu Y, Kang J, Li H, Zhang L, Yi H, Xiang X, Liu F, Sun L. p62/SQSTM1 involved in cisplatin resistance in human ovarian cancer cells by clearing ubiquitinated proteins. Eur J Cancer 2011; 47: 1585-94.
    • (2011) Eur J Cancer , vol.47 , pp. 1585-1594
    • Yu, H.1    Su, J.2    Xu, Y.3    Kang, J.4    Li, H.5    Zhang, L.6    Yi, H.7    Xiang, X.8    Liu, F.9    Sun, L.10
  • 30
    • 84890810356 scopus 로고    scopus 로고
    • The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation-and chemotherapy-induced cell death
    • Qiao S, Tao S, Rojo DLVM, Park SL, Vonderfecht AA, Jacobs SL, Zhang DD, Wondrak GT. The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation-and chemotherapy-induced cell death. Auto-phagy 2013; 9: 2087-102.
    • (2013) Auto-phagy , vol.9 , pp. 2087-2102
    • Qiao, S.1    Tao, S.2    Rojo, D.L.V.M.3    Park, S.L.4    Vonderfecht, A.A.5    Jacobs, S.L.6    Zhang, D.D.7    Wondrak, G.T.8
  • 31
    • 84856857494 scopus 로고    scopus 로고
    • Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells
    • Ajabnoor GM, Crook T, Coley HM. Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells. Cell Death Dis 2012; 3: e260.
    • (2012) Cell Death Dis , vol.3
    • Ajabnoor, G.M.1    Crook, T.2    Coley, H.M.3
  • 32
    • 84879899136 scopus 로고    scopus 로고
    • Regulation of LC3-Dependent Protective Autophagy in Ovarian Cancer Cells by Protein Phosphatase 2A
    • Yin X, Zhang N, Di W. Regulation of LC3-Dependent Protective Autophagy in Ovarian Cancer Cells by Protein Phosphatase 2A. Int J Gynecol Cancer 2013; 23: 630-641.
    • (2013) Int J Gynecol Cancer , vol.23 , pp. 630-641
    • Yin, X.1    Zhang, N.2    Di, W.3
  • 33
    • 77954599053 scopus 로고    scopus 로고
    • p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
    • Jain A, Lamark T, Sjottem E, Larsen KB, Awuh JA, Overvatn A, McMahon M, Hayes JD, Johansen T. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem 2010; 285: 22576-91.
    • (2010) J Biol Chem , vol.285 , pp. 22576-22591
    • Jain, A.1    Lamark, T.2    Sjottem, E.3    Larsen, K.B.4    Awuh, J.A.5    Overvatn, A.6    McMahon, M.7    Hayes, J.D.8    Johansen, T.9
  • 35
    • 80052350645 scopus 로고    scopus 로고
    • Potential role of p62 in tumor development
    • Komatsu M. Potential role of p62 in tumor development. Autophagy 2011; 7: 1088-90.
    • (2011) Autophagy , vol.7 , pp. 1088-1090
    • Komatsu, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.