Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer

Oncotarget

Volumn 6, Issue 18, 2015, Pages 16411-16421

  Xia, Shu ^a,b   Kohli, Manish ^c   Du, Meijun ^b   Dittmar, Rachel L ^b   Lee, Adam ^d   Nandy, Debashis ^c   Yuan, Tiezheng ^b   Guo, Yongchen ^b   Wang, Yuan ^b   Tschannen, Michael R ^b   Worthey, Elizabeth ^b   Jacob, Howard ^b   See, William ^b   Kilari, Deepak ^b   Wang, Xuexia ^e   Hovey, Raymond L ^e   Huang, Chiang Ching ^e   Wang, Liang ^b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c MAYO CLINIC   (United States)

^d MAYO GRADUATE SCHOOL   (United States)

^e UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Cell free DNA; Liquid biopsy; Next generation sequencing; Plasma; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR; ANTIANDROGEN; DNA; ERG PROTEIN, HUMAN; HYBRID PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, HUMAN; SERINE PROTEINASE; TMPRSS2 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR ERG;

ANDROGEN DEPRIVATION THERAPY; ANDROGEN SYNTHESIS; ARTICLE; BIOPSY; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER STAGING; CELL FREE SYSTEM; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA REPAIR; ENZYME ACTIVATION; FEASIBILITY STUDY; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; LIQUID BIOPSY; MALE; OVERALL SURVIVAL; PLASMA GENOMIC ABNORMALITY SCORE; PROSTATE CANCER; SCORING SYSTEM; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR VOLUME; AGED; BLOOD; CHEMISTRY; DNA SEQUENCE; GENE DOSAGE; GENE LIBRARY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN GENOME; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY; PLASMA; PROSTATE; PROSTATIC NEOPLASMS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANDROGEN ANTAGONISTS; BASE SEQUENCE; BIOPSY; DNA COPY NUMBER VARIATIONS; DNA, NEOPLASM; GENE DOSAGE; GENE LIBRARY; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; PLASMA; PROSTATE; PROSTATIC NEOPLASMS; PTEN PHOSPHOHYDROLASE; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS, DNA; SERINE ENDOPEPTIDASES; TRANS-ACTIVATORS; TRANSCRIPTIONAL REGULATOR ERG; TREATMENT OUTCOME;

EID: 84937898954     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3845     Document Type: Article

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