-
1
-
-
0037389094
-
2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference
-
PID: 12682500
-
Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G, Sccm/Esicm/Accp/Ats/Sis (2003) 2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference. Crit Care Med 31:1250–1256
-
(2003)
Crit Care Med
, vol.31
, pp. 1250-1256
-
-
Levy, M.M.1
Fink, M.P.2
Marshall, J.C.3
Abraham, E.4
Angus, D.5
Cook, D.6
Cohen, J.7
Opal, S.M.8
Vincent, J.L.9
Ramsay, G.10
-
2
-
-
84883076264
-
Severe sepsis and septic shock
-
COI: 1:CAS:528:DC%2BC3sXhtlyis7fF, PID: 23984731
-
Angus DC, van der Poll T (2013) Severe sepsis and septic shock. N Engl J Med 369:840–851
-
(2013)
N Engl J Med
, vol.369
, pp. 840-851
-
-
Angus, D.C.1
van der Poll, T.2
-
3
-
-
84897378109
-
The new normal: immunomodulatory agents against sepsis immune suppression
-
COI: 1:CAS:528:DC%2BC2cXhvFGrtbg%3D, PID: 24485901
-
Hutchins NA, Unsinger J, Hotchkiss RS, Ayala A (2014) The new normal: immunomodulatory agents against sepsis immune suppression. Trends Mol Med 20:224–233
-
(2014)
Trends Mol Med
, vol.20
, pp. 224-233
-
-
Hutchins, N.A.1
Unsinger, J.2
Hotchkiss, R.S.3
Ayala, A.4
-
4
-
-
84897377065
-
Why have clinical trials in sepsis failed?
-
PID: 24581450
-
Marshall JC (2014) Why have clinical trials in sepsis failed? Trends Mol Med 20:195–203
-
(2014)
Trends Mol Med
, vol.20
, pp. 195-203
-
-
Marshall, J.C.1
-
5
-
-
84939969644
-
-
Singer M: Do we need a new definition of sepsis? Intensive Care Med
-
Shankar-Hari M, Deutschman CS, Singer M (2015) Do we need a new definition of sepsis? Intensive Care Med. doi:10.1007/s00134-015-3680-x
-
(2015)
Deutschman CS
-
-
Shankar-Hari, M.1
-
6
-
-
84857879859
-
An evaluation of the feasibility, cost and value of information of a multicentre randomised controlled trial of intravenous immunoglobulin for sepsis (severe sepsis and septic shock): incorporating a systematic review, meta-analysis and value of information analysis
-
COI: 1:STN:280:DC%2BC38rgsVOrtg%3D%3D
-
Soares MO, Welton NJ, Harrison DA, Peura P, Shankar-Hari M, Harvey SE, Madan JJ, Ades AE, Palmer SJ, Rowan KM (2012) An evaluation of the feasibility, cost and value of information of a multicentre randomised controlled trial of intravenous immunoglobulin for sepsis (severe sepsis and septic shock): incorporating a systematic review, meta-analysis and value of information analysis. Health Technol Assess 16:1–186
-
(2012)
Health Technol Assess
, vol.16
-
-
Soares, M.O.1
Welton, N.J.2
Harrison, D.A.3
Peura, P.4
Shankar-Hari, M.5
Harvey, S.E.6
Madan, J.J.7
Ades, A.E.8
Palmer, S.J.9
Rowan, K.M.10
-
7
-
-
84858394440
-
Bench-to-bedside review: immunoglobulin therapy for sepsis—biological plausibility from a critical care perspective
-
PID: 22424150
-
Shankar-Hari M, Spencer J, Sewell WA, Rowan KM, Singer M (2012) Bench-to-bedside review: immunoglobulin therapy for sepsis—biological plausibility from a critical care perspective. Crit Care 16:206
-
(2012)
Crit Care
, vol.16
, pp. 206
-
-
Shankar-Hari, M.1
Spencer, J.2
Sewell, W.A.3
Rowan, K.M.4
Singer, M.5
-
8
-
-
0035100888
-
Biomarkers and surrogate endpoints: preferred definitions and conceptual framework
-
Biomarkers Definitions Working G (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 69:89–95
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 89-95
-
-
Biomarkers Definitions Working, G.1
-
9
-
-
77953127347
-
Biomarkers and surrogate end points—the challenge of statistical validation
-
PID: 20368727
-
Buyse M, Sargent DJ, Grothey A, Matheson A, de Gramont A (2010) Biomarkers and surrogate end points—the challenge of statistical validation. Nat Rev Clin Oncol 7:309–317
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 309-317
-
-
Buyse, M.1
Sargent, D.J.2
Grothey, A.3
Matheson, A.4
de Gramont, A.5
-
10
-
-
84973292549
-
-
(2014) Abstracts for ESICM-Barcelona 2014. Intensive Care Med 40(Suppl 1):1–308
-
(2014)
Intensive Care Med
, vol.40
-
-
-
11
-
-
69149107165
-
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
-
PID: 19622511
-
Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264–269
-
(2009)
Ann Intern Med
, vol.151
, pp. 264-269
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
Group, P.5
-
12
-
-
0026724481
-
The ACCP-SCCM consensus conference on sepsis and organ failure
-
COI: 1:STN:280:DyaK383ovFartA%3D%3D, PID: 1600757
-
Bone RC, Sibbald WJ, Sprung CL (1992) The ACCP-SCCM consensus conference on sepsis and organ failure. Chest 101:1481–1483
-
(1992)
Chest
, vol.101
, pp. 1481-1483
-
-
Bone, R.C.1
Sibbald, W.J.2
Sprung, C.L.3
-
13
-
-
80054718314
-
Early natural killer cell counts in blood predict mortality in severe sepsis
-
PID: 22018048
-
Andaluz-Ojeda D, Iglesias V, Bobillo F, Almansa R, Rico L, Gandia F, Loma AM, Nieto C, Diego R, Ramos E, Nocito M, Resino S, Eiros JM, Tamayo E, de Lejarazu RO, Bermejo-Martin JF (2011) Early natural killer cell counts in blood predict mortality in severe sepsis. Crit Care 15:R243
-
(2011)
Crit Care
, vol.15
, pp. R243
-
-
Andaluz-Ojeda, D.1
Iglesias, V.2
Bobillo, F.3
Almansa, R.4
Rico, L.5
Gandia, F.6
Loma, A.M.7
Nieto, C.8
Diego, R.9
Ramos, E.10
Nocito, M.11
Resino, S.12
Eiros, J.M.13
Tamayo, E.14
de Lejarazu, R.O.15
Bermejo-Martin, J.F.16
-
14
-
-
84922393941
-
Immunoglobulins IgG1, IgM and IgA: a synergistic team influencing survival in sepsis
-
COI: 1:CAS:528:DC%2BC2cXhs1Sqt7%2FP, PID: 24815605
-
Bermejo-Martin JF, Rodriguez-Fernandez A, Herran-Monge R, Andaluz-Ojeda D, Muriel-Bombin A, Merino P, Garcia-Garcia MM, Citores R, Gandia F, Almansa R, Blanco J, Group G (2014) Immunoglobulins IgG1, IgM and IgA: a synergistic team influencing survival in sepsis. J Intern Med 276:404–412
-
(2014)
J Intern Med
, vol.276
, pp. 404-412
-
-
Bermejo-Martin, J.F.1
Rodriguez-Fernandez, A.2
Herran-Monge, R.3
Andaluz-Ojeda, D.4
Muriel-Bombin, A.5
Merino, P.6
Garcia-Garcia, M.M.7
Citores, R.8
Gandia, F.9
Almansa, R.10
Blanco, J.11
Group, G.12
-
15
-
-
75749148392
-
Immunotherapy improves immune homeostasis and increases survival rate of septic patients
-
COI: 1:CAS:528:DC%2BC3cXitVSiur0%3D, PID: 19930904
-
Huang SW, Chen J, Ouyang B, Yang CH, Chen MY, Guan XD (2009) Immunotherapy improves immune homeostasis and increases survival rate of septic patients. Chin J Traumatol 12:344–349
-
(2009)
Chin J Traumatol
, vol.12
, pp. 344-349
-
-
Huang, S.W.1
Chen, J.2
Ouyang, B.3
Yang, C.H.4
Chen, M.Y.5
Guan, X.D.6
-
16
-
-
0028361044
-
Analysis of immunoglobulin isotype levels in acute pneumococcal bacteremia and in convalescence
-
COI: 1:STN:280:DyaK2czkvF2ksA%3D%3D, PID: 8070449
-
Ekdahl K, Rollof J, Oxelius VA, Engellau J, Braconier JH (1994) Analysis of immunoglobulin isotype levels in acute pneumococcal bacteremia and in convalescence. Eur J Clin Microbiol Infect Dis 13:374–378
-
(1994)
Eur J Clin Microbiol Infect Dis
, vol.13
, pp. 374-378
-
-
Ekdahl, K.1
Rollof, J.2
Oxelius, V.A.3
Engellau, J.4
Braconier, J.H.5
-
17
-
-
84973281436
-
Endogenous immunoglobulin subclasses and isotypes in septic shock patients in the postoperative period
-
Heredia-Rodriguez M, Gutierrez-Junco S, Gomez-Sanchez E, Alvarez-Fuente E, Ruiz-Granado P, Almansa R (2013) Endogenous immunoglobulin subclasses and isotypes in septic shock patients in the postoperative period. Eur J Anaesthesiol 30:185
-
(2013)
Eur J Anaesthesiol
, vol.30
, pp. 185
-
-
Heredia-Rodriguez, M.1
Gutierrez-Junco, S.2
Gomez-Sanchez, E.3
Alvarez-Fuente, E.4
Ruiz-Granado, P.5
Almansa, R.6
-
18
-
-
81855185315
-
Assessment of plasmatic immunoglobulin G, A and M levels in septic shock patients
-
COI: 1:CAS:528:DC%2BC3MXhsFegt77L, PID: 21924385
-
Venet F, Gebeile R, Bancel J, Guignant C, Poitevin-Later F, Malcus C, Lepape A, Monneret G (2011) Assessment of plasmatic immunoglobulin G, A and M levels in septic shock patients. Int Immunopharmacol 11:2086–2090
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 2086-2090
-
-
Venet, F.1
Gebeile, R.2
Bancel, J.3
Guignant, C.4
Poitevin-Later, F.5
Malcus, C.6
Lepape, A.7
Monneret, G.8
-
19
-
-
84870658458
-
Beneficial role of endogenous immunoglobulin subclasses and isotypes in septic shock
-
COI: 1:CAS:528:DC%2BC38XhsFGjt7%2FJ, PID: 23089676
-
Tamayo E, Fernandez A, Almansa R, Carrasco E, Goncalves L, Heredia M, Andaluz-Ojeda D, March G, Rico L, Gomez-Herreras JI, de Lejarazu RO, Bermejo-Martin JF (2012) Beneficial role of endogenous immunoglobulin subclasses and isotypes in septic shock. J Crit Care 27:616–622
-
(2012)
J Crit Care
, vol.27
, pp. 616-622
-
-
Tamayo, E.1
Fernandez, A.2
Almansa, R.3
Carrasco, E.4
Goncalves, L.5
Heredia, M.6
Andaluz-Ojeda, D.7
March, G.8
Rico, L.9
Gomez-Herreras, J.I.10
de Lejarazu, R.O.11
Bermejo-Martin, J.F.12
-
20
-
-
70349660078
-
Gamma-globulin levels in patients with community-acquired septic shock
-
COI: 1:CAS:528:DC%2BD1MXhtFanu7zP, PID: 19295479
-
Taccone FS, Stordeur P, De Backer D, Creteur J, Vincent JL (2009) Gamma-globulin levels in patients with community-acquired septic shock. Shock 32:379–385
-
(2009)
Shock
, vol.32
, pp. 379-385
-
-
Taccone, F.S.1
Stordeur, P.2
De Backer, D.3
Creteur, J.4
Vincent, J.L.5
-
21
-
-
84872834736
-
Immunological monitoring to prevent and treat sepsis
-
PID: 23351425
-
Almansa R, Wain J, Tamayo E, Andaluz-Ojeda D, Martin-Loeches I, Ramirez P, Bermejo-Martin JF (2013) Immunological monitoring to prevent and treat sepsis. Crit Care 17:109
-
(2013)
Crit Care
, vol.17
, pp. 109
-
-
Almansa, R.1
Wain, J.2
Tamayo, E.3
Andaluz-Ojeda, D.4
Martin-Loeches, I.5
Ramirez, P.6
Bermejo-Martin, J.F.7
-
22
-
-
36448971653
-
Score-based immunoglobulin G therapy of patients with sepsis: the SBITS study
-
COI: 1:CAS:528:DC%2BD2sXhsVGhsrrJ, PID: 18074471
-
Werdan K, Pilz G, Bujdoso O, Fraunberger P, Neeser G, Schmieder RE, Viell B, Marget W, Seewald M, Walger P, Stuttmann R, Speichermann N, Peckelsen C, Kurowski V, Osterhues HH, Verner L, Neumann R, Muller-Werdan U, Score-Based Immunoglobulin Therapy of Sepsis Study G (2007) Score-based immunoglobulin G therapy of patients with sepsis: the SBITS study. Crit Care Med 35:2693–2701
-
(2007)
Crit Care Med
, vol.35
, pp. 2693-2701
-
-
Werdan, K.1
Pilz, G.2
Bujdoso, O.3
Fraunberger, P.4
Neeser, G.5
Schmieder, R.E.6
Viell, B.7
Marget, W.8
Seewald, M.9
Walger, P.10
Stuttmann, R.11
Speichermann, N.12
Peckelsen, C.13
Kurowski, V.14
Osterhues, H.H.15
Verner, L.16
Neumann, R.17
Muller-Werdan, U.18
Score-Based Immunoglobulin Therapy of Sepsis Study, G.19
-
23
-
-
84973281442
-
Low levels of immunoglobulin G in patients with sepsis or septic shock: a signum mali ominis?
-
Dietz S, Lautenschlaeger C, Mueller-Werdan U, Werdan K (2010) Low levels of immunoglobulin G in patients with sepsis or septic shock: a signum mali ominis? Crit Care 14:P26
-
(2010)
Crit Care
, vol.14
, pp. P26
-
-
Dietz, S.1
Lautenschlaeger, C.2
Mueller-Werdan, U.3
Werdan, K.4
-
24
-
-
84937813513
-
Low immunoglobulin G levels at admission reduced the odds for 28 day mortality compared to normal levels: prospective cohort study in severe sepsis
-
(abstract 0177)
-
Shankar-Hari M, Singer M, Cornelius V, Sanderson B, Gordon A, Terblanche M, Rowan K, Beale R, Spencer J (2013) Low immunoglobulin G levels at admission reduced the odds for 28 day mortality compared to normal levels: prospective cohort study in severe sepsis. Intensive Care Med 39(2):151 (abstract 0177)
-
(2013)
Intensive Care Med
, vol.39
, Issue.2
, pp. 151
-
-
Shankar-Hari, M.1
Singer, M.2
Cornelius, V.3
Sanderson, B.4
Gordon, A.5
Terblanche, M.6
Rowan, K.7
Beale, R.8
Spencer, J.9
-
25
-
-
77951450203
-
Gamma-globulin levels in patients with community-acquired septic shock
-
PID: 20395773, author reply 557
-
Myrianthefs PM, Boutzouka E, Baltopoulos GJ (2010) Gamma-globulin levels in patients with community-acquired septic shock. Shock 33:556–557; author reply 557
-
(2010)
Shock
, vol.33
, pp. 556-557
-
-
Myrianthefs, P.M.1
Boutzouka, E.2
Baltopoulos, G.J.3
-
26
-
-
77956635947
-
Sepsis and endothelial permeability
-
COI: 1:CAS:528:DC%2BC3cXhtVaktbvJ, PID: 20818861
-
Lee WL, Slutsky AS (2010) Sepsis and endothelial permeability. N Engl J Med 363:689–691
-
(2010)
N Engl J Med
, vol.363
, pp. 689-691
-
-
Lee, W.L.1
Slutsky, A.S.2
-
27
-
-
70449825100
-
Structural difference in the complement activation site of human IgG1 and IgG3
-
COI: 1:CAS:528:DC%2BD1MXhs1Sjt7nK, PID: 19906198
-
Michaelsen TE, Sandlie I, Bratlie DB, Sandin RH, Ihle O (2009) Structural difference in the complement activation site of human IgG1 and IgG3. Scand J Immunol 70:553–564
-
(2009)
Scand J Immunol
, vol.70
, pp. 553-564
-
-
Michaelsen, T.E.1
Sandlie, I.2
Bratlie, D.B.3
Sandin, R.H.4
Ihle, O.5
-
28
-
-
84871858066
-
Antibody orientation at bacterial surfaces is related to invasive infection
-
COI: 1:CAS:528:DC%2BC38XhvVOitbzL, PID: 23230002
-
Nordenfelt P, Waldemarson S, Linder A, Morgelin M, Karlsson C, Malmstrom J, Bjorck L (2012) Antibody orientation at bacterial surfaces is related to invasive infection. J Exp Med 209:2367–2381
-
(2012)
J Exp Med
, vol.209
, pp. 2367-2381
-
-
Nordenfelt, P.1
Waldemarson, S.2
Linder, A.3
Morgelin, M.4
Karlsson, C.5
Malmstrom, J.6
Bjorck, L.7
-
29
-
-
84930084195
-
Persistent lymphopenia after diagnosis of sepsis predicts mortality
-
PID: 25051284
-
Drewry AM, Samra N, Skrupky LP, Fuller BM, Compton SM, Hotchkiss RS (2014) Persistent lymphopenia after diagnosis of sepsis predicts mortality. Shock 42:383–391
-
(2014)
Shock
, vol.42
, pp. 383-391
-
-
Drewry, A.M.1
Samra, N.2
Skrupky, L.P.3
Fuller, B.M.4
Compton, S.M.5
Hotchkiss, R.S.6
-
30
-
-
14844343217
-
Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure
-
COI: 1:CAS:528:DC%2BD2MXitVehtLk%3D, PID: 15749917
-
Felmet KA, Hall MW, Clark RS, Jaffe R, Carcillo JA (2005) Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure. J Immunol 174:3765–3772
-
(2005)
J Immunol
, vol.174
, pp. 3765-3772
-
-
Felmet, K.A.1
Hall, M.W.2
Clark, R.S.3
Jaffe, R.4
Carcillo, J.A.5
-
31
-
-
84874938284
-
Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly
-
PID: 23328259
-
Inoue S, Suzuki-Utsunomiya K, Okada Y, Taira T, Iida Y, Miura N, Tsuji T, Yamagiwa T, Morita S, Chiba T, Sato T, Inokuchi S (2013) Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly. Crit Care Med 41:810–819
-
(2013)
Crit Care Med
, vol.41
, pp. 810-819
-
-
Inoue, S.1
Suzuki-Utsunomiya, K.2
Okada, Y.3
Taira, T.4
Iida, Y.5
Miura, N.6
Tsuji, T.7
Yamagiwa, T.8
Morita, S.9
Chiba, T.10
Sato, T.11
Inokuchi, S.12
-
32
-
-
84255194001
-
Immunosuppression in patients who die of sepsis and multiple organ failure
-
COI: 1:CAS:528:DC%2BC3MXhs1OhtbrF, PID: 22187279
-
Boomer JS, To K, Chang KC, Takasu O, Osborne DF, Walton AH, Bricker TL, Jarman SD 2nd, Kreisel D, Krupnick AS, Srivastava A, Swanson PE, Green JM, Hotchkiss RS (2011) Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA 306:2594–2605
-
(2011)
JAMA
, vol.306
, pp. 2594-2605
-
-
Boomer, J.S.1
To, K.2
Chang, K.C.3
Takasu, O.4
Osborne, D.F.5
Walton, A.H.6
Bricker, T.L.7
Jarman, S.D.8
Kreisel, D.9
Krupnick, A.S.10
Srivastava, A.11
Swanson, P.E.12
Green, J.M.13
Hotchkiss, R.S.14
-
33
-
-
84862766869
-
A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis
-
PID: 22742734
-
Boomer JS, Shuherk-Shaffer J, Hotchkiss RS, Green JM (2012) A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis. Crit Care 16:R112
-
(2012)
Crit Care
, vol.16
, pp. R112
-
-
Boomer, J.S.1
Shuherk-Shaffer, J.2
Hotchkiss, R.S.3
Green, J.M.4
-
35
-
-
84902511727
-
The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?
-
COI: 1:CAS:528:DC%2BC2cXpvV2ksro%3D, PID: 24717456
-
Opal SM, Dellinger RP, Vincent JL, Masur H, Angus DC (2014) The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C? Crit Care Med 42:1714–1721
-
(2014)
Crit Care Med
, vol.42
, pp. 1714-1721
-
-
Opal, S.M.1
Dellinger, R.P.2
Vincent, J.L.3
Masur, H.4
Angus, D.C.5
|