Esophageal cancer-derived microvesicles induce regulatory B cells

Cell Biochemistry and Function

Volumn 33, Issue 5, 2015, Pages 308-313

  Li, Yun ^a   An, Jun ^a   Huang, Shaohong ^a   He, Jinyuan ^a   Zhang, Junhang ^a  

^a THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

B lymphocyte; Esophagus cancer; Extracellular vesicles; Immune tolerance; Microvesicles; TGF

Indexed keywords

GELATINASE B; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; LATENCY-ASSOCIATED PROPEPTIDE, TGF-BETA; MMP9 PROTEIN, HUMAN; PEPTIDE; PROTEIN PRECURSOR;

ARTICLE; B LYMPHOCYTE; CANCER TISSUE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; ESOPHAGUS CANCER; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; MEMBRANE MICROPARTICLE; PRIORITY JOURNAL; SUPERNATANT; WESTERN BLOTTING; CYTOLOGY; ESOPHAGUS TUMOR; IMMUNOLOGY; METABOLISM; PATHOLOGY; TUMOR ESCAPE;

B-LYMPHOCYTES, REGULATORY; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL-DERIVED MICROPARTICLES; CELLS, CULTURED; ESOPHAGEAL NEOPLASMS; HUMANS; MATRIX METALLOPROTEINASE 9; PEPTIDES; PROTEIN PRECURSORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR ESCAPE;

EID: 84937813758     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.3115     Document Type: Article

References (18)

1. Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol 2006; 6: 715-727. doi:10.1038/nri1936.
2. Sideras K, Braat H, Kwekkeboom J, et al. Role of the immune system in pancreatic cancer progression and immune modulating treatment strategies. Cancer Treat Rev 2014; 40: 513-522. doi:10.1016/j.ctrv.2013.11.005.
3. Martin F, Apetoh L, Ghiringhelli F. Controversies on the role of Th17 in cancer: a TGF-beta-dependent immunosuppressive activity? Trend Mol Med 2012; 18: 742-749. doi:10.1016/j.molmed.2012.09.007.
4. Soyer OU, Akdis M, Ring J, et al. Mechanisms of peripheral tolerance to allergens. Allergy 2013; 68: 161-170. doi:10.1111/all.12085.
5. Sweetwyne MT, Murphy-Ullrich JE. Thrombospondin1 in tissue repair and fibrosis: TGF-beta-dependent and independent mechanisms. Matrix Biol 2012; 31: 178-186. doi:10.1016/j.matbio.2012.01.006.
6. Wilson TJ, Nannuru KC, Singh RK. Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction. Mol Cancer Res 2009; 7: 1224-1233. doi:10.1158/1541-7786.mcr-09-0028.
7. Shi M, Zhu J, Wang R, et al. Latent TGF-beta structure and activation. Nature 2011; 474: 343-349. doi:10.1038/nature10152.
8. Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA. GARP regulates the bioavailability and activation of TGFbeta. Mol Biol Cell 2012; 23: 1129-1139. doi:10.1091/mbc.E11-12-1018.
9. Venkatraman L, Chia SM, Narmada BC, et al. Plasmin triggers a switch-like decrease in thrombospondin-dependent activation of TGF-beta1. Biophysic J 2012; 103: 1060-1068. doi:10.1016/j.bpj.2012.06.050.
10. Li L, Tan J, Zhang Y, et al. DLK1 promotes lung cancer cell invasion through upregulation of MMP9 expression depending on Notch signaling. PLoS One 2014; 9: e91509. doi:10.1371/journal.pone.0091509.
11. Zhang Y, Li L, Yu J, et al. Microvesicle-mediated delivery of transforming growth factor beta1 siRNA for the suppression of tumor growth in mice. Biomaterials 2014; 35: 4390-4400. doi:10.1016/j.biomaterials.2014.02.003.
12. Luketic L, Delanghe J, Sobol PT, et al. Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. J Immunol 2007; 179: 5024-5032.
13. Mempel TR, Bauer CA. Intravital imaging of CD8+ T cell function in cancer. Clin Exp Metast 2009; 26: 311-327. doi:10.1007/s10585-008-9196-9.
14. He WA, Calore F, Londhe P, Canella A, Guttridge DC, Croce CM. Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7. Proc Natl Acad Sci U S A 2014; 111: 4525-4529. doi:10.1073/pnas.1402714111.
15. Liu Y, Zhao L, Li D, et al. Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development. Protein Cell 2013; 4: 932-941. doi:10.1007/s13238-013-3092-z.
16. Chen X, Song CH, Feng BS, et al. Intestinal epithelial cell-derived integrin alphabeta6 plays an important role in the induction of regulatory T cells and inhibits an antigen-specific Th2 response. J Leuko Biol 2011; 90: 751-759. doi:10.1189/jlb.1210696.
17. Wang BQ, Zhang CM, Gao W, Wang XF, Zhang HL, Yang PC. Cancer-derived matrix metalloproteinase-9 contributes to tumor tolerance. J Cancer Res Clin Oncol 2011; 137: 1525-1533. doi:10.1007/s00432-011-1010-4.
18. Song SS, Yuan PF, Chen JY, et al. TGF-beta favors bone marrow-derived dendritic cells to acquire tolerogenic properties. Immun Invest 2014; 43: 360-369. doi:10.3109/08820139.2013.879172.