Ang-(1-7) promotes the migration and invasion of human renal cell carcinoma cells via Mas-mediated AKT signaling pathway

Biochemical and Biophysical Research Communications

Volumn 460, Issue 2, 2015, Pages 333-340

  Zheng, Shuai ^a   Yang, Ying ^a   Song, Ran ^a   Yang, Xiaomei ^a   Liu, Hua ^a   Ma, Qian ^a   Yang, Longyan ^a   Meng, Ran ^a   Tao, Tao ^a   Wang, Songlin ^a   He, Junqi ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

AKT signaling; Angiotensin (1 7); Invasion; Mas receptor; Migration; Renal cell carcinoma

Indexed keywords

ANGIOTENSIN I; ANGIOTENSIN I (1-7); G PROTEIN COUPLED RECEPTOR; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTEIN KINASE B; PROTO-ONCOGENE PROTEINS C-MAS-1;

DRUG EFFECTS; ENZYMOLOGY; HUMAN; KIDNEY TUMOR; METABOLISM; METASTASIS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR INVASION; WOUND HEALING;

ANGIOTENSIN I; CELL LINE, TUMOR; HUMANS; KIDNEY NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 84937762582     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.035     Document Type: Article

References (37)

1. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2012 CA Cancer J. Clin. 62 2012 10 29
2. J.R. Bhatt, and A. Finelli Landmarks in the diagnosis and treatment of renal cell carcinoma Nat. Rev. Urol. 11 2014 517 525
3. U. Athar, and T.C. Gentile Treatment options for metastatic renal cell carcinoma: a review Can. J. Urol. 15 2008 3954 3966
4. J. Hadoux, S. Vignot, and T. De La Motte Rouge Renal cell carcinoma: focus on safety and efficacy of temsirolimus Clin. Med. Insights Oncol. 4 2010 143 154
5. G. Banumathy, and P. Cairns Signaling pathways in renal cell carcinoma Cancer Biol. Ther. 10 2010 658 664
6. D. Su, L. Stamatakis, E.A. Singer, and R. Srinivasan Renal cell carcinoma: molecular biology and targeted therapy Curr. Opin. Oncol. 26 2014 321 327
7. D. Yamada, H. Matsushita, T. Azuma, T. Nakagawa, M. Nagata, Y. Yamada, M. Suzuki, T. Fujimura, H. Fukuhara, H. Kume, Y. Homma, and K. Kakimi Granulocyte macrophage colony-stimulating factor as a predictor of the response of metastatic renal cell carcinoma to tyrosine kinase inhibitor therapy Mol. Clin. Oncol. 2 2014 1023 1027
8. R.A. Santos, A.C. Simoes e Silva, C. Maric, D.M. Silva, R.P. Machado, I. de Buhr, S. Heringer-Walther, S.V. Pinheiro, M.T. Lopes, M. Bader, E.P. Mendes, V.S. Lemos, M.J. Campagnole-Santos, H.P. Schultheiss, R. Speth, and T. Walther Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas Proc. Natl. Acad. Sci. U. S. A. 100 2003 8258 8263
9. N. Alenina, P. Xu, B. Rentzsch, E.L. Patkin, and M. Bader Genetically altered animal models for Mas and angiotensin-(1-7) Exp. Physiol. 93 2008 528 537
10. M. Iwai, and M. Horiuchi Devil and angel in the renin-angiotensin system: ACE-angiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis Hypertens. Res. 32 2009 533 536
11. J. Menon, D.R. Soto-Pantoja, M.F. Callahan, J.M. Cline, C.M. Ferrario, E.A. Tallant, and P.E. Gallagher Angiotensin-(1-7) inhibits growth of human lung adenocarcinoma xenografts in nude mice through a reduction in cyclooxygenase-2 Cancer Res. 67 2007 2809 2815
12. D.R. Soto-Pantoja, J. Menon, P.E. Gallagher, and E.A. Tallant Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor Mol. Cancer Ther. 8 2009 1676 1683
13. K.L. Cook, L.J. Metheny-Barlow, E.A. Tallant, and P.E. Gallagher Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors Cancer Res. 70 2010 8319 8328
14. D.J. Fogarty, M.V. Sanchez-Gomez, and C. Matute Multiple angiotensin receptor subtypes in normal and tumor astrocytes in vitro Glia 39 2002 304 313
15. J. Zimpelmann, and K.D. Burns Angiotensin-(1-7) activates growth-stimulatory pathways in human mesangial cells Am. J. Physiol. Ren. Physiol. 296 2009 F337 F346
16. W.C. Burns, E. Velkoska, R. Dean, L.M. Burrell, and M.C. Thomas Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways Am. J. Physiol. Ren. Physiol. 299 2010 F585 F593
17. M. Dilauro, and K.D. Burns Angiotensin-(1-7) and its effects in the kidney ScientificWorldJournal 9 2009 522 535
18. W. Bian, L. Sun, L. Yang, J.F. Li, J. Hu, S. Zheng, R. Guo, D. Feng, Q. Ma, X. Shi, Y. Xiong, X. Yang, R. Song, J. Xu, S. Wang, and J. He Stabilization of the angiotensin-(1-7) receptor Mas through interaction with PSD95 Biochem. J. 453 2013 345 356
19. Y.R. Chin, and A. Toker Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer Cell. Signaling 21 2009 470 476
20. C. Sourbier, V. Lindner, H. Lang, A. Agouni, E. Schordan, S. Danilin, S. Rothhut, D. Jacqmin, J.J. Helwig, and T. Massfelder The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy Cancer Res. 66 2006 5130 5142
21. J. Bain, L. Plater, M. Elliott, N. Shpiro, C.J. Hastie, H. McLauchlan, I. Klevernic, J.S. Arthur, D.R. Alessi, and P. Cohen The selectivity of protein kinase inhibitors: a further update Biochem. J. 408 2007 297 315
22. E.I. Ager, J. Neo, and C. Christophi The renin-angiotensin system and malignancy Carcinogenesis 29 2008 1675 1684
23. A.J. George, W.G. Thomas, and R.D. Hannan The renin-angiotensin system and cancer: old dog, new tricks Nat. Rev. Cancer 10 2010 745 759
24. V. Esteban, S. Heringer-Walther, A. Sterner-Kock, R. de Bruin, S. van den Engel, Y. Wang, S. Mezzano, J. Egido, H.P. Schultheiss, M. Ruiz-Ortega, and T. Walther Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation PLoS One 4 2009 e5406
25. Y. Shao, M. He, L. Zhou, T. Yao, Y. Huang, and L.M. Lu Chronic angiotensin (1-7) injection accelerates STZ-induced diabetic renal injury Acta Pharmacol. Sin. 29 2008 829 837
26. V. Cernaro, A. Lacquaniti, V. Donato, M.R. Fazio, A. Buemi, and M. Buemi Fibrosis, regeneration and cancer: what is the link? Nephrol. Dial. Transpl. 27 2011 21 27
27. L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867
28. A.R. de Vivar Chevez, J. Finke, and R. Bukowski The role of inflammation in kidney cancer Adv. Exp. Med. Biol. 816 2014 197 234
29. D. Young, G. Waitches, C. Birchmeier, O. Fasano, and M. Wigler Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains Cell 45 1986 711 719
30. A. Horiguchi, M. Oya, A. Uchida, K. Marumo, and M. Murai Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma J. Urol. 169 2003 710 713
31. A.S. Merseburger, J. Hennenlotter, U. Kuehs, P. Simon, S. Kruck, E. Koch, A. Stenzl, and M.A. Kuczyk Activation of PI3K is associated with reduced survival in renal cell carcinoma Urol. Int. 80 2008 372 377
32. B. Krishnan, T.L. Smith, P. Dubey, M.E. Zapadka, F.M. Torti, M.C. Willingham, E.A. Tallant, and P.E. Gallagher Angiotensin-(1-7) attenuates metastatic prostate cancer and reduces osteoclastogenesis Prostate 73 2013 71 82
33. L. Ni, Y. Feng, H. Wan, Q. Ma, L. Fan, Y. Qian, Q. Li, Y. Xiang, and B. Gao Angiotensin-(1-7) inhibits the migration and invasion of A549 human lung adenocarcinoma cells through inactivation of the PI3K/Akt and MAPK signaling pathways Oncol. Rep. 27 2011 783 790
34. V. Fendrich, N.M. Chen, M. Neef, J. Waldmann, M. Buchholz, G. Feldmann, E.P. Slater, A. Maitra, and D.K. Bartsch The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer Gut 59 2010 630 637
35. S. Wilop, S. von Hobe, M. Crysandt, A. Esser, R. Osieka, and E. Jost Impact of angiotensin I converting enzyme inhibitors and angiotensin II type 1 receptor blockers on survival in patients with advanced non-small-cell lung cancer undergoing first-line platinum-based chemotherapy J. Cancer Res. Clin. Oncol. 135 2009 1429 1435
36. K. Kohara, K.B. Brosnihan, and C.M. Ferrario Angiotensin(1-7) in the spontaneously hypertensive rat Peptides 14 1993 883 891
37. M. Luque, P. Martin, N. Martell, C. Fernandez, K.B. Brosnihan, and C.M. Ferrario Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension J. Hypertens. 14 1996 799 805