Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response

Molecular Metabolism

Volumn 4, Issue 8, 2015, Pages 561-568

  Rojas, Jennifer M ^a   Matsen, Miles E ^a   Mundinger, Thomas O ^a   Morton, Gregory J ^a   Stefanovski, Darko ^c   Bergman, Richard N ^d   Kaiyala, Karl J ^e   Taborsky, Gerald J ^a,b   Schwartz, Michael W ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d CEDARS SINAI MEDICAL CENTER   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Central FGF receptors; FGF receptor inhibitor PD173074; Frequently sampled intravenous glucose tolerance test; Glucose metabolism; Minimal model; Sympathoadrenal response

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; ADRENALIN; CATECHOLAMINE; CORTICOSTERONE; FATTY ACID; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR RECEPTOR; GLUCAGON; LACTIC ACID; NORADRENALIN;

ACUTE STRESS; ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; INSULIN RELEASE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; LACTATE BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

RATTUS; RODENTIA;

EID: 84937730574     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2015.05.005     Document Type: Article

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