Serum level of IL-10 is increased in patients with endometriosis, and IL-10 promotes the growth of lesions in a murine model

American Journal of Pathology

Volumn 184, Issue 2, 2014, Pages 464-471

  Suen, Jau Ling ^a,b   Chang, Yu ^a,c   Chiu, Pu Rong ^a   Hsieh, Tsung Hua ^c   Hsi, Edward ^a,c   Chen, Yu Chieh ^a,c   Chen, Yu Fang ^a   Tsai, Eing Mei ^a,b,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CD86 ANTIGEN; GLYCOPROTEIN P 15095; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE CONTROL; DOWN REGULATION; ENDOMETRIOSIS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; MACROPHAGE; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PHENOTYPE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; REGULATORY T LYMPHOCYTE; SECRETORY CELL; TH1 CELL; TH2 CELL; YOUNG ADULT;

ADULT; ANIMALS; ANTIBODIES, BLOCKING; ANTIGENS, CD45; CASE-CONTROL STUDIES; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DEMOGRAPHY; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; ENDOMETRIOSIS; FEMALE; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-10; MALE; MICE; MICE, INBRED C57BL; PHENOTYPE;

EID: 84892187616     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.10.023     Document Type: Article

References (41)

1. L.C. Giudice, and L.C. Kao Endometriosis Lancet 364 2004 1789 1799
2. T.M. D'Hooghe, and S. Debrock Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons Hum Reprod Update 8 2002 84 88
3. C.A. Witz Interleukin-6: another piece of the endometriosis-cytokine puzzle Fertil Steril 73 2000 212 214
4. D.I. Lebovic, M.D. Mueller, and R.N. Taylor Immunobiology of endometriosis Fertil Steril 75 2001 1 10
5. W. Xu, A. Roos, N. Schlagwein, A.M. Woltman, M.R. Daha, and C. van Kooten IL-10-producing macrophages preferentially clear early apoptotic cells Blood 107 2006 4930 4937
6. S. Rutella, S. Danese, and G. Leone Tolerogenic dendritic cells: cytokine modulation comes of age Blood 108 2006 1435 1440
7. J.H. Fransen, J. van der Vlag, J. Ruben, G.J. Adema, J.H. Berden, and L.B. Hilbrands The role of dendritic cells in the pathogenesis of systemic lupus erythematosus Arthritis Res Ther 12 2010 207 214
8. R. Gazvani, and A. Templeton Peritoneal environment, cytokines and angiogenesis in the pathophysiology of endometriosis Reproduction 123 2002 217 226
9. J. Mier-Cabrera, L. Jiménez-Zamudio, E. García-Latorre, O. Cruz-Orozco, and C. Hernández-Guerrero Quantitative and qualitative peritoneal immune profiles. T-cell apoptosis and oxidative stress-associated characteristics in women with minimal and mild endometriosis BJOG 118 2011 6 16
10. S. Podgaec, M.S. Abrao, J.A. Dias Jr., L.V. Rizzo, R.M. de Oliveira, and E.C. Baracat Endometriosis: an inflammatory disease with a Th2 immune response component Hum Reprod 22 2007 1373 1379
11. T. Hirata, Y. Osuga, M. Takamura, A. Kodama, Y. Hirota, K. Koga, O. Yoshino, M. Harada, Y. Takemura, T. Yano, and Y. Taketani Recruitment of CCR6-expressing Th17 cells by CCL 20 secreted from IL-1 beta-, TNF-alpha-, and IL-17A-stimulated endometriotic stromal cells Endocrinology 151 2010 5468 5476
12. M. Berbic, A.J. Hey-Cunningham, C. Ng, N. Tokushige, S. Ganewatta, R. Markham, P. Russell, and I.S. Fraser The role of Foxp3+ regulatory T-cells in endometriosis: a potential controlling mechanism for a complex, chronic immunological condition Hum Reprod 25 2010 900 907
13. M. Berbic, and I.S. Fraser Regulatory T cells and other leukocytes in the pathogenesis of endometriosis J Reprod Immunol 88 2010 149 155
14. P. Basta, M. Majka, W. Jozwicki, E. Lukaszewska, A. Knafel, M. Grabiec, E. Stasienko, and L. Wicherek The frequency of CD25+CD4+ and FOXP3+ regulatory T cells in ectopic endometrium and ectopic decidua Reprod Biol Endocrinol 8 2010 116
15. A. Eidukaite, A. Siaurys, and V. Tamosiunas Aberrant expression of CD95 and CD69 molecules among CD56 cells in women with endometriosis Am J Reprod Immunol 55 2006 276 281
16. N. Tariverdian, F. Siedentopf, M. Rücke, S.M. Blois, B.F. Klapp, H. Kentenich, and P.C. Arck Intraperitoneal immune cell status in infertile women with and without endometriosis J Reprod Immunol 80 2009 80 90
17. L. Schulke, M. Berbic, F. Manconi, N. Tokushige, R. Markham, and I.S. Fraser Dendritic cell populations in the eutopic and ectopic endometrium of women with endometriosis Hum Reprod 24 2009 1695 1703
18. O. Fainaru, A. Adini, O. Benny, I. Adini, S. Short, L. Bazinet, K. Nakai, E. Pravda, M.D. Hornstein, R.J. D'Amato, and J. Folkman Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis FASEB J 22 2008 522 529
19. M.L. Hediger, H.J. Hartnett, and G.M. Louis Association of endometriosis with body size and figure Fertil Steril 84 2005 1366 1374
20. S. Kim, K.B. Elkon, and X. Ma Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells Immunity 21 2004 643 653
21. R.S. Jawa, S. Anillo, K. Huntoon, H. Baumann, and M. Kulaylat Analytic review: interleukin-6 in surgery, trauma, and critical care: part I: basic science J Intensive Care Med 26 2011 3 12
22. E. Carreras, S. Turner, M.B. Frank, N. Knowlton, J. Osban, M. Centola, C.G. Park, A. Simmons, J. Alberola-Ila, and S. Kovats Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4 Blood 115 2010 238 246
23. C.M. Hedrich, and J.H. Bream Cell type-specific regulation of IL-10 expression in inflammation and disease Immunol Res 47 2010 185 206
24. J.A. Sampson Metastatic or embolic endometriosis, due to the menstrual dissemination of endometrial tissue into the venous circulation Am J Pathol 3 1927 93 110.43
25. W.P. Dmowski, R.W. Steele, and G.F. Baker Deficient cellular immunity in endometriosis Am J Obstet Gynecol 141 1981 377 383
26. M.Y. Wu, and H.N. Ho The role of cytokines in endometriosis Am J Reprod Immunol 49 2003 285 296
27. E. Barcz, P. Kaminski, and L. Marianowski Role of cytokines in pathogenesis of endometriosis Med Sci Monit 6 2000 1042 1046
28. V.H. Eisenberg, M. Zolti, and D. Soriano Is there an association between autoimmunity and endometriosis? Autoimmun Rev 11 2012 806 814
29. H.N. Ho, M.Y. Wu, K.H. Chao, C.D. Chen, S.U. Chen, and Y.S. Yang Peritoneal interleukin-10 increases with decrease in activated CD4+ T lymphocytes in women with endometriosis Hum Reprod 12 1997 2528 2533
30. M.Y. Wu, H.N. Ho, S.U. Chen, K.H. Chao, C.D. Chen, and Y.S. Yang Increase in the production of interleukin-6, interleukin-10, and interleukin-12 by lipopolysaccharide-stimulated peritoneal macrophages from women with endometriosis Am J Reprod Immunol 41 1999 106 111
31. N. Rana, D.P. Braun, R. House, H. Gebel, C. Rotman, and W.P. Dmowski Basal and stimulated secretion of cytokines by peritoneal macrophages in women with endometriosis Fertil Steril 65 1996 925 930
32. X. Zhang, P. Hei, L. Deng, and J. Lin Interleukin-10 gene promoter polymorphisms and their protein production in peritoneal fluid in patients with endometriosis Mol Hum Reprod 13 2007 135 140
33. J. Xie, S. Wang, B. He, Y. Pan, Y. Li, Q. Zeng, H. Jiang, and J. Chen Association of estrogen receptor alpha and interleukin-10 gene polymorphisms with endometriosis in a Chinese population Fertil Steril 92 2009 54 60
34. W. Fan, S. Li, Q. Chen, Z. Huang, Q. Ma, and Z. Xiao Association between interleukin-10 promoter polymorphisms and endometriosis: a meta-analysis Gene 515 2013 49 55
35. S.H. Juo, R. Wu, C.S. Lin, M.T. Wu, J.N. Lee, and E.M. Tsai A functional promoter polymorphism in interleukin-10 gene influences susceptibility to endometriosis Fertil Steril 92 2009 1228 1233
36. L.A. Zaritsky, A. Dery, W.Y. Leong, L. Gama, and J.E. Clements Tissue-specific interferon alpha subtype response to SIV infection in brain, spleen, and lung J Interferon Cytokine Res 33 2013 24 33
37. J.H. Tinsley, S. South, V.L. Chiasson, and B.M. Mitchell Interleukin-10 reduces inflammation, endothelial dysfunction, and blood pressure in hypertensive pregnant rats Am J Physiol Regul Integr Comp Physiol 298 2010 R713 R719
38. N. Tewari, S. Kalkunte, D.W. Murray, and S. Sharma The water channel aquaporin 1 is a novel molecular target of polychlorinated biphenyls for in utero anomalies J Biol Chem 284 2009 15224 15232
39. M. Saraiva, and A. O'Garra The regulation of IL-10 production by immune cells Nat Rev Immunol 10 2010 170 181
40. N. Hanna, I. Hanna, M. Hleb, E. Wagner, J. Dougherty, D. Balkundi, J. Padbury, and S. Sharma Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts J Immunol 164 2000 5721 5728
41. A. Boonstra, R. Rajsbaum, M. Holman, R. Marques, C. Asselin-Paturel, J.P. Pereira, E.E. Bates, S. Akira, P. Vieira, Y.J. Liu, G. Trinchieri, and A. O'Garra Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals J Immunol 177 2006 7551 7558