20-Hydroxyeicosatetraenoic Acid Is a Key Mediator of Angiotensin II-induced Apoptosis in Cardiac Myocytes

Journal of Cardiovascular Pharmacology

Volumn 66, Issue 1, 2015, Pages 86-95

  Zhao, Huiying ^a   Qi, Guohua ^b   Han, Yong ^b   Shen, Xin ^b   Yao, Fanrong ^c   Xuan, Chengluan ^c   Gu, Yan ^c   Qian, Steven Y ^c   Zeng, Qinghua ^b   O'Rourke, Stephen T ^c   Sun, Chengwen ^c  

^a JILIN UNIVERSITY   (China)

^b NORTHEAST NORMAL UNIVERSITY   (China)

^c NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

20 HETE; angiotensin II; apoptosis; cardiac

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; APOPTOSIS INHIBITOR; CYTOCHROME P450 4A1; FORMAMIDINE; LOSARTAN; N HYDROXY N' (4 BUTYL 2 METHYLPHENYL)FORMAMIDINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG; 20-HYDROXY-5,8,11,14-EICOSATETRAENOIC ACID; HYDROXYICOSATETRAENOIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; HEART MITOCHONDRION; HEART MUSCLE CELL; INTRACELLULAR SIGNALING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDIATOR RELEASE; MITOCHONDRIAL MEMBRANE POTENTIAL; NEWBORN; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; DRUG EFFECTS; PHYSIOLOGY; WISTAR RAT;

ANGIOTENSIN II; ANIMALS; APOPTOSIS; CELLS, CULTURED; HYDROXYEICOSATETRAENOIC ACIDS; MYOCYTES, CARDIAC; RATS; RATS, WISTAR;

EID: 84937685202     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0000000000000248     Document Type: Article

References (30)

1. Baines CP, Molkentin JD. Stress signaling pathways that modulate cardiac myocyte apoptosis. J Mol Cell Cardiol. 2005;38:47-62.
2. Condorelli G, Morisco C, Stassi G, et al. Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat. Circulation. 1999;99:3071-3078.
3. Feuerstein GZ. Apoptosis-new opportunities for novel therapeutics for heart diseases. Cardiovasc Drugs Ther. 2001;15:547-551.
4. Kajstura J, Cigola E, Malhotra A, et al. Angiotensin II induces apoptosis of adult ventricular myocytes in vitro. J Mol Cell Cardiol. 1997;29:859-870.
5. Gonzalez A, Lopez B, Ravassa S, et al. Stimulation of cardiac apoptosis in essential hypertension: potential role of angiotensin II. Hypertension. 2002;39:75-80.
6. Zhang GX, Lu XM, Kimura S, et al. Role of mitochondria in angiotensin II-induced reactive oxygen species and mitogen-Activated protein kinase activation. Cardiovasc Res. 2007;76:204-212.
7. Green DR, Reed JC. Mitochondria and apoptosis. Science. 1998;281: 1309-1312.
8. Desagher S, Martinou JC. Mitochondria as the central control point of apoptosis. Trends Cell Biol. 2000;10:369-377.
9. Sun CW, Alonso-Galicia M, Taheri MR, et al. Nitric oxide-20-hydroxyeicosatetraenoic acid interaction in the regulation of K+ channel activity and vascular tone in renal arterioles. Circ Res. 1998;83:1069-1079.
10. 10. Ito O, Nakamura Y, Tan L, et al. Expression of cytochrome P-450 4 enzymes in the kidney and liver: regulation by PPAR and speciesdifference between rat and human. Mol Cell Biochem. 2006;284:141-148.
11. Lv X, Wan J, Yang J, et al. Cytochrome P450 omega-hydroxylase inhibition reduces cardiomyocyte apoptosis via activation of ERK1/2 signaling in rat myocardial ischemia-reperfusion. Eur J Pharmacol. 2008;596: 118-126.
12. Zordoky BN, Aboutabl ME, El-Kadi AO. Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats. Drug Metab Dispos. 2008;36:2277-2286.
13. Kroetz DL, Zeldin DC. Cytochrome P450 pathways of arachidonic acid metabolism. Curr Opin Lipidol. 2002;13:273-283.
14. Gross ER, Nithipatikom K, Hsu AK, et al. Cytochrome P450 omegahydroxylase inhibition reduces infarct size during reperfusion via the sarcolemmal KATP channel. J Mol Cell Cardiol. 2004;37:1245-1249.
15. Bao Y, Wang X, Li W, et al. 20-Hydroxyeicosatetraenoic acid induces apoptosis in neonatal rat cardiomyocytes through mitochondrialdependent pathways. J Cardiovasc Pharmacol. 2011;57:294-301.
16. Parmentier JH, Muthalif MM, Nishimoto AT, et al. 20-Hydroxyeicosatetraenoic acid mediates angiotensin ii-induced phospholipase d activation in vascular smooth muscle cells. Hypertension. 2001; 37:623-629.
17. Carroll MA, Balazy M, Huang DD, et al. Cytochrome P450-derived renal HETEs: storage and release. Kidney Int. 1997;51:1696-1702.
18. Alonso-Galicia M, Maier KG, Greene AS, et al. Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. Am J Physiol Regul Integr Comp Physiol. 2002;283:R60-R68.
19. Zeng Q, Zhou Q, Yao F, et al. Endothelin-1 regulates cardiac L-type calcium channels via NAD(P)H oxidase-derived superoxide. J Pharmacol Exp Ther. 2008;326:732-738.
20. Zeng Q, Han Y, Bao Y, et al. 20-HETE increases NADPH oxidasederived ROS production and stimulates the L-type Ca2+ channel via a PKC-dependent mechanism in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2010;299:H1109-H1117.
21. Yao F, Sumners C, O'Rourke ST, et al. Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats. Am J Physiol Heart Circ Physiol. 2008;294:H2712-H2720.
22. Ly JD, Grubb DR, Lawen A. The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update. Apoptosis. 2003;8:115-128.
23. Choudhary R, Baker KM, Pan J. All-trans retinoic acid prevents angiotensin II-And mechanical stretch-induced reactive oxygen species generation and cardiomyocyte apoptosis. J Cell Physiol. 2008;215:172-181.
24. Palomeque J, Delbridge L, Petroff MV. Angiotensin II: a regulator of cardiomyocyte function and survival. Front Biosci (Landmark Ed). 2009; 14:5118-5133.
25. Ito O, Roman RJ. Regulation of P-450 4A activity in the glomerulus of the rat. Am J Physiol. 1999;276:R1749-R1757.
26. Yaghini FA, Zhang C, Parmentier JH, et al. Contribution of arachidonic acid metabolites derived via cytochrome P4504A to angiotensin IIinduced neointimal growth. Hypertension. 2005;45:1182-1187.
27. Minuz P, Jiang H, Fava C, et al. Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease. Hypertension. 2008;51:1379-1385.
28. Nithipatikom K, Gross ER, Endsley MP, et al. Inhibition of cytochrome P450 omega-hydroxylase: a novel endogenous cardioprotective pathway. Circ Res. 2004;95:e65-e71.
29. Yousif MH, Benter IF, Roman RJ. Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury. Auton Autacoid Pharmacol. 2009;29:33-41.
30. Granville DJ, Tashakkor B, Takeuchi C, et al. Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. Proc Natl Acad Sci U S A. 2004;101:1321-1326.