Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury

Autonomic and Autacoid Pharmacology

Volumn 29, Issue 1-2, 2009, Pages 33-41

  Yousif, M H M ^a   Benter, I F ^a   Roman, R J ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

CDU; Diabetes; Glibenclamide; HET0016; Ischaemia; Reperfusion

Indexed keywords

1 CYCLOHEXYL 3 DODECYL UREA; 20 HYDROXYICOSATETRAENOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ARACHIDONIC ACID; CYTOCHROME P450; DIHYDROXYICOSATRIENOIC ACID; EPOXIDE HYDROLASE; EPOXYICOSATRIENOIC ACID; FORMAMIDINE; GLIBENCLAMIDE; N HYDROXY N' (4 BUTYL 2 METHYL PHENYL) FORMAMIDINE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY VASCULAR RESISTANCE; EXPERIMENTAL RAT; FATTY ACID SYNTHESIS; HEART; HEART DISEASE; HEART FUNCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART PERFUSION; HEART PROTECTION; MALE; METABOLITE; MICROSOME; NONHUMAN; RAT; REPERFUSION INJURY; STREPTOZOCIN DIABETES;

8,11,14-EICOSATRIENOIC ACID; AMIDINES; ANIMALS; ARACHIDONIC ACID; BLOOD GLUCOSE; BODY WEIGHT; CORONARY CIRCULATION; CYTOCHROME P-450 ENZYME SYSTEM; DIABETES MELLITUS, EXPERIMENTAL; ENZYME INHIBITORS; EPOXIDE HYDROLASES; GLYBURIDE; HEART; HYDROXYEICOSATETRAENOIC ACIDS; MALE; MICROSOMES; MYOCARDIUM; RATS; RATS, WISTAR; REPERFUSION INJURY; UREA; VASCULAR RESISTANCE; VENTRICULAR DYSFUNCTION, LEFT;

EID: 62549085552     PISSN: 14748665     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1474-8673.2009.00429.x     Document Type: Article

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