Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial

Complementary Therapies in Medicine

Volumn 23, Issue 3, 2015, Pages 318-324

  Khayat, Samira ^a,b   Fanaei, Hamed ^c,d   Kheirkhah, Masoomeh ^e,f   Moghadam, Zahra Behboodi ^b   Kasaeian, Amir ^b,g   Javadimehr, Mani ^d  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^g TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Behavioral symptoms; Curcumin; Mood symptoms; Physical symptoms; Premenstrual syndrome

Indexed keywords

CURCUMIN; PLACEBO;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG CAPSULE; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; MENSTRUATION; PREMENSTRUAL SYNDROME; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SYMPTOM; ABDOMINAL PAIN; ADOLESCENT; DRUG EFFECTS; HEADACHE; IRRITABILITY; PATHOPHYSIOLOGY; PHYTOTHERAPY; YOUNG ADULT;

ABDOMINAL PAIN; ADOLESCENT; ADULT; CURCUMIN; DOUBLE-BLIND METHOD; FEMALE; HEADACHE; HUMANS; IRRITABLE MOOD; PHYTOTHERAPY; PREMENSTRUAL SYNDROME; YOUNG ADULT;

EID: 84937630939     PISSN: 09652299     EISSN: 18736963     Source Type: Journal    
DOI: 10.1016/j.ctim.2015.04.001     Document Type: Article

References (42)

1. Khayat S., et al. Effect of treatment with ginger on the severity of premenstrual syndrome symptoms. ISRN Obstet Gynecol 2014, 2014:5.
2. Wichianpitaya J., Taneepanichskul S. A comparative efficacy of low-dose combined oral contraceptives containing desogestrel and drospirenone in premenstrual symptoms. Obstet Gynecol Int 2013, 2013:487143.
3. Seedhom A.E., Mohammed E.S., Mahfouz E.M. Life style factors associated with premenstrual syndrome among El-Minia University Students, Egypt. ISRN Public Health 2013, 2013:p6.
4. Jang S.H., Kim D.I., Choi M.S. Effects and treatment methods of acupuncture and herbal medicine for premenstrual syndrome/premenstrual dysphoric disorder: systematic review. BMC Complement Altern Med 2014, 14:11.
5. Whelan A.M., Jurgens T.M., Naylor H. Herbs, vitamins and minerals in the treatment of premenstrual syndrome: a systematic review. Can J Clin Pharmacol 2009, 16(3):e407-e429.
6. Kulkarni S., Dhir A., Akula K.K. Potentials of curcumin as an antidepressant. Sci World J 2009, 9:1233-1241.
7. Lopresti A.L., Hood S.D., Drummond P.D. Multiple antidepressant potential modes of action of curcumin: a review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects. J Psychopharmacol 2012, 26(12):1512-1524.
8. Halbreich U. The etiology, biology, and evolving pathology of premenstrual syndromes. Psychoneuroendocrinology 2003, 28(Suppl 3):55-99.
9. Rapkin A.J., Akopians A.L. Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorder. Menopause Int 2012, 18(2):52-59.
10. Pérez-López F.R.C., Peter Pérez-Roncero, Gonzalo López-Baena, María T., Cuadros-López José L. Premenstrual syndrome and premenstrual Dysphoric disorder: symptoms and cluster influences. Open Psychiatry J 2009, 3:39-49.
11. Brown J., et al. Selective serotonin reuptake inhibitors for premenstrual syndrome. Cochrane Database Syst Rev 2009, 2(2):1-123. (CD001396).
12. Budoff P.W. The use of prostaglandin inhibitors for the premenstrual syndrome. J Reprod Med 1983, 28(7):469-478.
13. Hong J., et al. Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase. Carcinogenesis 2004, 25(9):1671-1679.
14. Lee K.H., et al. A curcumin derivative: 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-gamma/LPS-stimulated macrophages. Molecules 2011, 16(11):9728-9738.
15. Moriyuki K., et al. Curcumin Inhibits the proteinase-activated receptor-2-triggered prostaglandin E2 production by suppressing cyclooxygenase-2 upregulation and Akt-dependent activation of nuclear factor-kappaB in human lung epithelial cells. J Pharmacol Sci 2010, 114(2):225-229.
16. Mythri R.B., Bharath M.M. Curcumin: a potential neuroprotective agent in Parkinson's disease. Curr Pharm Des 2012, 18(1):91-99.
17. Xu Y., et al. Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats. Pharmacol Biochem Behav 2005, 82(1):200-206.
18. Yonkers K.A., Pearlstein T.B., Gotman N. A pilot study to compare fluoxetine: calcium, and placebo in the treatment of premenstrual syndrome. J Clin Psychopharmacol 2013, 33(5):614-620.
19. Mira M., et al. Mefenamic acid in the treatment of premenstrual syndrome. Obstet Gynecol 1986, 68(3):395-398.
20. Sharifi F., et al. Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome. Complement Ther Clin Pract 2014, 20(1):81-88.
21. Marjoribanks J., et al. Selective serotonin reuptake inhibitors for premenstrual syndrome. Cochrane Database Syst Rev 2013, 6:1-157. (CD001396).
22. Blum I., et al. Lack of plasma norepinephrine cyclicity: increased estradiol during the follicular phase, and of progesterone and gonadotrophins at ovulation in women with premenstrual syndrome. Neuropsychobiology 2004, 50(1):10-15.
23. Arora V., et al. Curcumin ameliorates reserpine-induced pain-depression dyad: behavioural, biochemical, neurochemical and molecular evidences. Psychoneuroendocrinology 2011, 36(10):1570-1581.
24. Bishnoi M., Chopra K., Kulkarni S.K. Protective effect of Curcumin: the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain. Pharmacol Biochem Behav 2008, 88(4):511-522.
25. Ossewaarde L., et al. Changes in functioning of mesolimbic incentive processing circuits during the premenstrual phase. Soc Cogn Affect Neurosci 2011, 6(5):612-620.
26. Craig M.C., et al. Effect of long-term estrogen therapy on dopaminergic responsivity in post-menopausal women-a preliminary study. Psychoneuroendocrinology 2004, 29(10):1309-1316.
27. Thompson T.L., Moss R.L. Modulation of mesolimbic dopaminergic activity over the rat estrous cycle. Neurosci Lett 1997, 229(3):145-148.
28. Kuppers E., et al. Estrogen: a multifunctional messenger to nigrostriatal dopaminergic neurons. J Neurocytol 2000, 29(5-6):375-385.
29. Kulkarni S.K., Dhir A. An overview of curcumin in neurological disorders. Indian J Pharm Sci 2010, 72(2):149-154.
30. Kumar T.P., et al. Curcumin modulates dopaminergic receptor, CREB and phospholipase C gene expression in the cerebral cortex and cerebellum of streptozotocin induced diabetic rats. J Biomed Sci 2010, 17:43.
31. Yonkers K.A., O'Brien P.M., Eriksson E. Premenstrual syndrome. Lancet 2008, 371(9619):1200-1210.
32. Sanmukhani J., Anovadiya A., Tripathi C.B. Evaluation of antidepressant like activity of curcumin and its combination with fluoxetine and imipramine: an acute and chronic study. Acta Pol Pharm 2011, 68(5):769-775.
33. Wang R., et al. The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors. Eur J Pharmacol 2008, 578(1):43-50.
34. Kulkarni S.K., Bhutani M.K., Bishnoi M. Antidepressant activity of curcumin: involvement of serotonin and dopamine system. Psychopharmacology (Berl) 2008, 201(3):435-442.
35. Chandran B., Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res 2012, 26(11):1719-1725.
36. Dulbecco P., Savarino V. Therapeutic potential of curcumin in digestive diseases. World J Gastroenterol 2013, 19(48):9256-9270.
37. Ganjali S., et al. Investigation of the effects of curcumin on serum cytokines in obese individuals: a randomized controlled trial. The Sci World J 2014, 2014:p6.
38. Klickovic U., et al. Human pharmacokinetics of high dose oral curcumin and its effect on heme oxygenase-1 expression in healthy male subjects. BioMed Res Int 2014, 2014:7.
39. Kaur G., Amelioration of Obesity M.C. Glucose Intolerance, and Oxidative Stress in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats by Combination Consisting of "curcumin with piperine and quercetin". ISRN Pharmacol 2012, 2012:7.
40. Verma R.K., Chellappan D.K., Pandey A.K. Review on treatment of premenstrual syndrome: from conventional to alternative approach. J Basic Clin Physiol Pharmacol 2014, 1:1-11.
41. Kong J.C., Lee M.S., Shin B.C. Randomized clinical trials on acupuncture in korean literature: a systematic review. Evid Based Complement Alternat Med 2009, 6(1):41-48.
42. Adams J.D., Garcia C. Women's health among the Chumash. Evid-Based Complement Altern Med 2006, 3(1):125-131.