A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPSStimulated macrophages

Molecules

Volumn 16, Issue 11, 2011, Pages 9728-9738

  Lee, Ka Heng ^a   Abas, Faridah ^a   Alitheen, Noorjahan Banu Mohamed ^a   Shaari, Khozirah ^a   Lajis, Nordin Haji ^a   Ahmad, Syahida ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Anti inflammatory; BDMC33; Cyclooxygenase; PGE 2; RAW264.7

Indexed keywords

2,6 BIS(2,5 DIMETHOXYBENZYLIDENE)CYCLOHEXANONE; 2,6-BIS(2,5-DIMETHOXYBENZYLIDENE)CYCLOHEXANONE; BENZYLIDENE DERIVATIVE; CYCLOHEXANONE DERIVATIVE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; CYCLOOXYGENASE 3; CYCLOOXYGENASE-3; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, MOUSE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; DRUG EFFECT; GENE EXPRESSION; GENETICS; MACROPHAGE; METABOLISM; MOUSE; SECRETION; SYNTHESIS;

ANIMALS; BENZYLIDENE COMPOUNDS; CELL LINE; CELL SURVIVAL; CYCLOHEXANONES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; GENE EXPRESSION; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 82255172127     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16119728     Document Type: Article

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