Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 779, Issue , 2015, Pages 124-133

  Sanchez, Jamila R ^b   Reddick, Traci L ^c   Perez, Marissa ^b   Centonze, Victoria E ^d   Mitra, Sankar ^e   Izumi, Tadahide ^f   McMahan, C Alex ^b   Walter, Christi A ^a,b,g  

^a SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^b University of Texas Health Science Center   (United States)

^c DUKE CANCER INSTITUTE   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^f Dept of Nutrition and Food Science   (United States)

^g UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

APEX1; DNA repair; LacI; Mutagenesis; Paternal age; Spermatogenesis

Indexed keywords

AP ENDONUCLEASE 1; DEOXYRIBONUCLEASE I; UNCLASSIFIED DRUG; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL POPULATION; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GERMLINE MUTATION; IN VITRO STUDY; MALE; MIDDLE AGED; MOUSE; MUTAGENESIS; NONHUMAN; PATERNAL AGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCTIVE HEALTH; SOMATIC CELL; YOUNG ADULT; ANIMAL; BIOSYNTHESIS; DNA REPAIR; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; SPERMATOGENESIS; SPERMATOZOON; TRANSGENIC MOUSE;

MURINAE; MUS; MUS MUSCULUS;

ANIMALS; APOPTOSIS; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM-LINE MUTATION; HUMANS; MALE; MICE; MICE, TRANSGENIC; MUTAGENESIS; PATERNAL AGE; SPERMATOGENESIS; SPERMATOZOA;

EID: 84937572476     PISSN: 00275107     EISSN: 18792871     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2015.06.008     Document Type: Article

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