메뉴 건너뛰기




Volumn 2014, Issue 1, 2014, Pages 1-7

Multiple myeloma: A model for scientific and clinical progress

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MODEL; DRUG RESISTANCE; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MULTIPLE MYELOMA; PATHOLOGY; PROGNOSIS; TREATMENT OUTCOME;

EID: 84937559363     PISSN: 15204391     EISSN: 15204383     Source Type: Journal    
DOI: 10.1182/asheducation-2014.1.1     Document Type: Article
Times cited : (19)

References (45)
  • 1
    • 84892409192 scopus 로고    scopus 로고
    • Widespread genetic heterogeneity in multiple myeloma: Implications for targeted therapy
    • Lohr JG, Stojanov P, Carter SL, et al. Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy. Cancer Cell. 2014;25(1):91-101.
    • (2014) Cancer Cell , vol.25 , Issue.1 , pp. 91-101
    • Lohr, J.G.1    Stojanov, P.2    Carter, S.L.3
  • 2
    • 84860219443 scopus 로고    scopus 로고
    • The genetic architecture of multiple myeloma
    • Morgan GJ, Walker BA, Davies FE. The genetic architecture of multiple myeloma. Nat Rev Cancer. 2012;12(5):335-348.
    • (2012) Nat Rev Cancer , vol.12 , Issue.5 , pp. 335-348
    • Morgan, G.J.1    Walker, B.A.2    Davies, F.E.3
  • 3
    • 74049162897 scopus 로고    scopus 로고
    • International Myeloma Working Group molecular classification of multiple myeloma: Spotlight review
    • Fonseca R, Bergsagel PL, Drach J, et al. International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. Leukemia. 2009;23(12):2210-2221.
    • (2009) Leukemia , vol.23 , Issue.12 , pp. 2210-2221
    • Fonseca, R.1    Bergsagel, P.L.2    Drach, J.3
  • 4
    • 79952781038 scopus 로고    scopus 로고
    • Multiple myeloma
    • Palumbo A, Anderson K. Multiple myeloma. N Engl J Med. 2011; 364(11):1046-1060.
    • (2011) N Engl J Med , vol.364 , Issue.11 , pp. 1046-1060
    • Palumbo, A.1    Anderson, K.2
  • 5
    • 84894041669 scopus 로고    scopus 로고
    • Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy
    • Mulligan G, Lichter DI, Di Bacco A, et al. Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy. Blood. 2014;123(5):632-639.
    • (2014) Blood , vol.123 , Issue.5 , pp. 632-639
    • Mulligan, G.1    Lichter, D.I.2    Di Bacco, A.3
  • 6
    • 33745779502 scopus 로고    scopus 로고
    • The molecular classification of multiple myeloma
    • Zhan F, Huang Y, Colla S, et al. The molecular classification of multiple myeloma. Blood. 2006;108(6):2020-2028.
    • (2006) Blood , vol.108 , Issue.6 , pp. 2020-2028
    • Zhan, F.1    Huang, Y.2    Colla, S.3
  • 7
    • 78751508049 scopus 로고    scopus 로고
    • Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma
    • Walker BA, Wardell CP, Chiecchio L, et al. Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma. Blood. 2011;117(2):553-562.
    • (2011) Blood , vol.117 , Issue.2 , pp. 553-562
    • Walker, B.A.1    Wardell, C.P.2    Chiecchio, L.3
  • 8
    • 77949423427 scopus 로고    scopus 로고
    • Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling
    • Gutierrez NC, Sarasquete ME, Misiewicz-Krzeminska I, et al. Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling. Leukemia. 2010;24(3):629-637.
    • (2010) Leukemia , vol.24 , Issue.3 , pp. 629-637
    • Gutierrez, N.C.1    Sarasquete, M.E.2    Misiewicz-Krzeminska, I.3
  • 9
    • 77957936826 scopus 로고    scopus 로고
    • Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
    • Pichiorri F, Suh SS, Rocci A, et al. Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development. Cancer Cell. 2010;18(4):367-381.
    • (2010) Cancer Cell , vol.18 , Issue.4 , pp. 367-381
    • Pichiorri, F.1    Suh, S.S.2    Rocci, A.3
  • 10
    • 84871233578 scopus 로고    scopus 로고
    • SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status
    • Lopez-Corral L, Sarasquete ME, Bea S, et al. SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status. Leukemia. 2012;26(12):2521-2529.
    • (2012) Leukemia , vol.26 , Issue.12 , pp. 2521-2529
    • Lopez-Corral, L.1    Sarasquete, M.E.2    Bea, S.3
  • 11
    • 84892699941 scopus 로고    scopus 로고
    • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
    • Bolli N, Avet-Loiseau H, Wedge DC, et al. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma. Nat Commun. 2014;5:2997.
    • (2014) Nat Commun , vol.5 , pp. 2997
    • Bolli, N.1    Avet-Loiseau, H.2    Wedge, D.C.3
  • 12
    • 84904860974 scopus 로고    scopus 로고
    • Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma
    • Zhu YX, Braggio E, Shi CX, et al. Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma. Blood. 2014;124(4):536-545.
    • (2014) Blood , vol.124 , Issue.4 , pp. 536-545
    • Zhu, Y.X.1    Braggio, E.2    Shi, C.X.3
  • 14
    • 84856086596 scopus 로고    scopus 로고
    • High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma
    • Paiva B, Gutierrez NC, Rosinol L, et al. High-risk cytogenetics and persistent minimal residual disease by multiparameter flow cytometry predict unsustained complete response after autologous stem cell transplantation in multiple myeloma. Blood. 2012;119(3):687-691.
    • (2012) Blood , vol.119 , Issue.3 , pp. 687-691
    • Paiva, B.1    Gutierrez, N.C.2    Rosinol, L.3
  • 15
    • 33845546906 scopus 로고    scopus 로고
    • Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: T(4;14) is the most relevant adverse prognostic factor, whereas Rb deletion as a unique abnormality is not associated with adverse prognosis
    • Gutierrez NC, Castellanos MV, Martin ML, et al. Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated with adverse prognosis. Leukemia. 2007;21(1):143-150.
    • (2007) Leukemia , vol.21 , Issue.1 , pp. 143-150
    • Gutierrez, N.C.1    Castellanos, M.V.2    Martin, M.L.3
  • 16
    • 84856706335 scopus 로고    scopus 로고
    • A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: Analysis of patients treated in the MRC Myeloma IX trial
    • Boyd KD, Ross FM, Chiecchio L, et al. A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial. Leukemia. 2012;26(2):349-355.
    • (2012) Leukemia , vol.26 , Issue.2 , pp. 349-355
    • Boyd, K.D.1    Ross, F.M.2    Chiecchio, L.3
  • 17
    • 84873595098 scopus 로고    scopus 로고
    • Improving overall survival and overcoming adverse prognosis in the treatment of cytogenetically high-risk multiple myeloma
    • Bergsagel PL, Mateos MV, Gutierrez NC, Rajkumar SV, San Miguel JF. Improving overall survival and overcoming adverse prognosis in the treatment of cytogenetically high-risk multiple myeloma. Blood. 2013; 121(6):884-892.
    • (2013) Blood , vol.121 , Issue.6 , pp. 884-892
    • Bergsagel, P.L.1    Mateos, M.V.2    Gutierrez, N.C.3    Rajkumar, S.V.4    San Miguel, J.F.5
  • 18
    • 84902279177 scopus 로고    scopus 로고
    • Double vs single autologous stem cell transplantation after bortezomib-based induction regimens for multiple myeloma: An integrated analysis of patient-level data from phase III European studies [abstract]
    • Cavo M, Salwender H, Rosinõl L, et al. Double vs single autologous stem cell transplantation after bortezomib-based induction regimens for multiple myeloma: an integrated analysis of patient-level data from phase III European studies [abstract]. Blood (ASH Annual Meeting Abstracts). 2013;122(21):767.
    • (2013) Blood (ASH Annual Meeting Abstracts) , vol.122 , Issue.21 , pp. 767
    • Cavo, M.1    Salwender, H.2    Rosinõl, L.3
  • 19
    • 82955189267 scopus 로고    scopus 로고
    • Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation
    • Zamagni E, Patriarca F, Nanni C, et al. Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation. Blood. 2011;118(23):5989-5995.
    • (2011) Blood , vol.118 , Issue.23 , pp. 5989-5995
    • Zamagni, E.1    Patriarca, F.2    Nanni, C.3
  • 20
    • 84883872187 scopus 로고    scopus 로고
    • Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: Impact on outcome in the Medical Research Council Myeloma IX Study
    • Rawstron AC, Child JA, de Tute RM, et al. Minimal residual disease assessed by multiparameter flow cytometry in multiple myeloma: impact on outcome in the Medical Research Council Myeloma IX Study. J Clin Oncol. 2013;31(20):2540-2547.
    • (2013) J Clin Oncol , vol.31 , Issue.20 , pp. 2540-2547
    • Rawstron, A.C.1    Child, J.A.2    De Tute, R.M.3
  • 21
    • 84901411165 scopus 로고    scopus 로고
    • Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma
    • Martinez-Lopez J, Lahuerta JJ, Pepin F, et al. Prognostic value of deep sequencing method for minimal residual disease detection in multiple myeloma. Blood. 2014;123(20):3073-3079.
    • (2014) Blood , vol.123 , Issue.20 , pp. 3073-3079
    • Martinez-Lopez, J.1    Lahuerta, J.J.2    Pepin, F.3
  • 22
    • 76249096571 scopus 로고    scopus 로고
    • How i treat multiple myeloma in younger patients
    • Stewart AK, Richardson PG, San-Miguel JF. How I treat multiple myeloma in younger patients. Blood. 2009;114(27):5436-5443.
    • (2009) Blood , vol.114 , Issue.27 , pp. 5436-5443
    • Stewart, A.K.1    Richardson, P.G.2    San-Miguel, J.F.3
  • 23
    • 58249097191 scopus 로고    scopus 로고
    • Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma
    • Kyle RA, Rajkumar SV. Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma. Leukemia. 2009; 23(1):3-9.
    • (2009) Leukemia , vol.23 , Issue.1 , pp. 3-9
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 24
    • 84880862419 scopus 로고    scopus 로고
    • Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma
    • Mateos MV, Hernandez MT, Giraldo P, et al. Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma. N Engl J Med. 2013;369(5):438-447.
    • (2013) N Engl J Med , vol.369 , Issue.5 , pp. 438-447
    • Mateos, M.V.1    Hernandez, M.T.2    Giraldo, P.3
  • 26
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: A randomised phase 3 study
    • Cavo M, Tacchetti P, Patriarca F, et al. Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet. 2010;376(9758):2075-2085.
    • (2010) Lancet , vol.376 , Issue.9758 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3
  • 27
    • 33644833147 scopus 로고    scopus 로고
    • Thalidomide and hematopoieticcell transplantation for multiple myeloma
    • Barlogie B, Tricot G, Anaissie E, et al. Thalidomide and hematopoieticcell transplantation for multiple myeloma. N Engl J Med. 2006;354(10): 1021-1030.
    • (2006) N Engl J Med , vol.354 , Issue.10 , pp. 1021-1030
    • Barlogie, B.1    Tricot, G.2    Anaissie, E.3
  • 28
    • 85021026684 scopus 로고    scopus 로고
    • Early autologous stem cell transplantation improves survival in newly diagnosed multiple myeloma patients [abstract]
    • Cavallo F, Spencer A, Gay F, et al. Early autologous stem cell transplantation improves survival in newly diagnosed multiple myeloma patients [abstract]. Haematologica. 2014;S1338.
    • (2014) Haematologica , pp. S1338
    • Cavallo, F.1    Spencer, A.2    Gay, F.3
  • 29
    • 84863576232 scopus 로고    scopus 로고
    • Bortezomib-thalidomidedexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma
    • Cavo M, Pantani L, Petrucci MT, et al. Bortezomib-thalidomidedexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma. Blood. 2012;120(1):9-19.
    • (2012) Blood , vol.120 , Issue.1 , pp. 9-19
    • Cavo, M.1    Pantani, L.2    Petrucci, M.T.3
  • 30
    • 84862937267 scopus 로고    scopus 로고
    • The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis
    • Morgan GJ, Gregory WM, Davies FE, et al. The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis. Blood. 2012;119(1):7-15.
    • (2012) Blood , vol.119 , Issue.1 , pp. 7-15
    • Morgan, G.J.1    Gregory, W.M.2    Davies, F.E.3
  • 31
    • 84860741191 scopus 로고    scopus 로고
    • Lenalidomide after stem-cell transplantation for multiple myeloma
    • McCarthy PL, Owzar K, Hofmeister CC, et al. Lenalidomide after stem-cell transplantation for multiple myeloma. N Engl J Med. 2012; 366(19):1770-1781.
    • (2012) N Engl J Med , vol.366 , Issue.19 , pp. 1770-1781
    • McCarthy, P.L.1    Owzar, K.2    Hofmeister, C.C.3
  • 32
    • 84885782934 scopus 로고    scopus 로고
    • Melphalan/prednisone/lenalidomide (MPR) versus high-dose melphalan and autologous transplantation (MEL200) plus lenalidomide maintenance or no maintenance in newly diagnosed multiple myeloma (MM) patients [abstract]
    • Boccadoro M, Cavallo F, Gay FM, et al. Melphalan/prednisone/lenalidomide (MPR) versus high-dose melphalan and autologous transplantation (MEL200) plus lenalidomide maintenance or no maintenance in newly diagnosed multiple myeloma (MM) patients [abstract]. ASCO Meeting Abstracts. 2013;31(15 suppl):8509.
    • (2013) ASCO Meeting Abstracts , vol.31 , Issue.15 , pp. 8509
    • Boccadoro, M.1    Cavallo, F.2    Gay, F.M.3
  • 33
    • 84865171981 scopus 로고    scopus 로고
    • Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: Results of the randomized phase III HOVON-65/GMMG-HD4 trial
    • Sonneveld P, Schmidt-Wolf IG, van der Holt B, et al. Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/GMMG-HD4 trial. J Clin Oncol. 2012;30(24):2946-2955.
    • (2012) J Clin Oncol , vol.30 , Issue.24 , pp. 2946-2955
    • Sonneveld, P.1    Schmidt-Wolf, I.G.2    Van Der Holt, B.3
  • 34
    • 78650623731 scopus 로고    scopus 로고
    • International Myeloma Working Group consensus statement regarding the current status of allogeneic stem-cell transplantation for multiple myeloma
    • Lokhorst H, Einsele H, Vesole D, et al. International Myeloma Working Group consensus statement regarding the current status of allogeneic stem-cell transplantation for multiple myeloma. J Clin Oncol. 2010; 28(29):4521-4530.
    • (2010) J Clin Oncol , vol.28 , Issue.29 , pp. 4521-4530
    • Lokhorst, H.1    Einsele, H.2    Vesole, D.3
  • 35
    • 34848833957 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reducedintensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
    • Facon T, Mary JY, Hulin C, et al. Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reducedintensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial. Lancet. 2007; 370(9594):1209-1218.
    • (2007) Lancet , vol.370 , Issue.9594 , pp. 1209-1218
    • Facon, T.1    Mary, J.Y.2    Hulin, C.3
  • 36
    • 84860744403 scopus 로고    scopus 로고
    • Continuous lenalidomide treatment for newly diagnosed multiple myeloma
    • Palumbo A, Hajek R, Delforge M, et al. Continuous lenalidomide treatment for newly diagnosed multiple myeloma. N Engl J Med. 2012;366(19):1759-1769.
    • (2012) N Engl J Med , vol.366 , Issue.19 , pp. 1759-1769
    • Palumbo, A.1    Hajek, R.2    Delforge, M.3
  • 37
    • 84898026370 scopus 로고    scopus 로고
    • Initial phase 3 results of the FIRST (Frontline Investigation of Lenalidomide Dexamethasone Versus Standard Thalidomide) trial (MM-020/IFM 07 01) in newly diagnosed multiple myeloma (NDMM) patients (pts) ineligible for stem cell transplantation (SCT) [abstract]
    • Facon T, Dimopoulos MA, Dispenzieri A, et al. Initial phase 3 results of the FIRST (Frontline Investigation Of Lenalidomide Dexamethasone Versus Standard Thalidomide) trial (MM-020/IFM 07 01) in newly diagnosed multiple myeloma (NDMM) patients (pts) ineligible for stem cell transplantation (SCT) [abstract]. Blood (ASH Annual Meeting Abstracts). 2013;122(21):2.
    • (2013) Blood (ASH Annual Meeting Abstracts) , vol.122 , Issue.21 , pp. 2
    • Facon, T.1    Dimopoulos, M.A.2    Dispenzieri, A.3
  • 38
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • San Miguel JF, Schlag R, Khuageva NK, et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med. 2008;359(9):906-917.
    • (2008) N Engl J Med , vol.359 , Issue.9 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 39
    • 77957344540 scopus 로고    scopus 로고
    • Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: A randomised trial
    • Mateos MV, Oriol A, Martinez-Lopez J, et al. Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial. Lancet Oncol. 2010;11(10):934-941.
    • (2010) Lancet Oncol , vol.11 , Issue.10 , pp. 934-941
    • Mateos, M.V.1    Oriol, A.2    Martinez-Lopez, J.3
  • 40
    • 84896372437 scopus 로고    scopus 로고
    • Bortezomib-melphalanprednisone-thalidomide followed by maintenance with bortezomibthalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: Updated follow-up and improved survival
    • Palumbo A, Bringhen S, Larocca A, et al. Bortezomib-melphalanprednisone-thalidomide followed by maintenance with bortezomibthalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: updated follow-up and improved survival. J Clin Oncol. 2014;32(7):634-640.
    • (2014) J Clin Oncol , vol.32 , Issue.7 , pp. 634-640
    • Palumbo, A.1    Bringhen, S.2    Larocca, A.3
  • 41
    • 84899066044 scopus 로고    scopus 로고
    • Phenotypic, genomic and functional characterization reveals no differences between CD138+ and CD138low subpopulations in multiple myeloma cell lines
    • Paino T, Sarasquete ME, Paiva B, et al. Phenotypic, genomic and functional characterization reveals no differences between CD138+ and CD138low subpopulations in multiple myeloma cell lines. PloS One. 2014;9(3):e92378.
    • (2014) PloS One , vol.9 , Issue.3 , pp. e92378
    • Paino, T.1    Sarasquete, M.E.2    Paiva, B.3
  • 42
    • 84884702483 scopus 로고    scopus 로고
    • Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): A randomised, open-label, phase 3 trial
    • San Miguel J, Weisel K, Moreau P, et al. Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial. Lancet Oncol. 2013;14(11):1055-1066.
    • (2013) Lancet Oncol , vol.14 , Issue.11 , pp. 1055-1066
    • San Miguel, J.1    Weisel, K.2    Moreau, P.3
  • 43
    • 84867295563 scopus 로고    scopus 로고
    • A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
    • Siegel DS, Martin T, Wang M, et al. A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma. Blood. 2012;120(14):2817-2825.
    • (2012) Blood , vol.120 , Issue.14 , pp. 2817-2825
    • Siegel, D.S.1    Martin, T.2    Wang, M.3
  • 44
    • 84884703399 scopus 로고    scopus 로고
    • Vorinostat or placebo in combination with bortezomib in patients with multiple myeloma (VANTAGE 088): A multicentre, randomised, double-blind study
    • Dimopoulos M, Siegel DS, Lonial S, et al. Vorinostat or placebo in combination with bortezomib in patients with multiple myeloma (VANTAGE 088): a multicentre, randomised, double-blind study. Lancet Oncol. 2013;14(11):1129-1140.
    • (2013) Lancet Oncol , vol.14 , Issue.11 , pp. 1129-1140
    • Dimopoulos, M.1    Siegel, D.S.2    Lonial, S.3
  • 45
    • 84884699420 scopus 로고    scopus 로고
    • PANORAMA 2: Panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma
    • Richardson PG, Schlossman RL, Alsina M, et al. PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma. Blood. 2013;122(14):2331-2337.
    • (2013) Blood , vol.122 , Issue.14 , pp. 2331-2337
    • Richardson, P.G.1    Schlossman, R.L.2    Alsina, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.