Is the Association of Hypertension With Cardiovascular Events Stronger Among the Lean and Normal Weight Than Among the Overweight and Obese?: The Multi-Ethnic Study of Atherosclerosis

Hypertension

Volumn 66, Issue 2, 2015, Pages 286-293

  Colangelo, Laura A ^a   Vu, Thanh Huyen T ^a   Szklo, Moyses ^b   Burke, Gregory L ^c   Sibley, Christopher ^d   Liu, Kiang ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Blood pressure; Cardiovascular disease; Follow up studies; Hypertension; Obesity; Risk; Waist circumference

Indexed keywords

ADULT; AGED; ARTICLE; ASIAN AMERICAN; BLACK PERSON; BODY MASS; CALCIUM INTAKE; CALORIC INTAKE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAUCASIAN; DISEASE ASSOCIATION; ETHNIC DIFFERENCE; EXERCISE; FEMALE; HISPANIC; HUMAN; HYPERTENSION; LEAN BODY WEIGHT; MAGNESIUM INTAKE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OBESITY; POTASSIUM INTAKE; PRIORITY JOURNAL; SEX DIFFERENCE; SODIUM INTAKE; WAIST CIRCUMFERENCE; ABDOMINAL OBESITY; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASES; COMPARATIVE STUDY; COMPLICATION; ETHNOLOGY; FOLLOW UP; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR; VERY ELDERLY;

ADIPOSITY; AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; AGED, 80 AND OVER; ASIAN AMERICANS; ATHEROSCLEROSIS; BODY MASS INDEX; CARDIOVASCULAR DISEASES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; HISPANIC AMERICANS; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; OBESITY; OBESITY, ABDOMINAL; OVERWEIGHT; RISK FACTORS; SEX FACTORS; WAIST CIRCUMFERENCE;

EID: 84937544878     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.04863     Document Type: Article

References (39)

1. Go AS, Mozaffarian D, Roger VL, American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics-2014 update: A report from the American Heart Association. Circulation 2014 129 e28 e292. doi: 10.1161/01.cir.0000441139.02102.80
2. Gelber RP, Gaziano JM, Manson JE, Buring JE, Sesso HD., A prospective study of body mass index and the risk of developing hypertension in men. Am J Hypertens 2007;20:370-377. doi: 10.1016/j.amjhyper.2006.10.011
3. Ong KL, Cheung BM, Man YB, Lau CP, Lam KS., Prevalence, awareness, treatment, and control of hypertension among United States adults 1999-2004. Hypertension 2007;49:69-75. doi: 10.1161/01.HYP.0000252676.46043.18
4. Cambien F, Chretien JM, Ducimetiere P, Guize L, Richard JL., Is the relationship between blood pressure and cardiovascular risk dependent on body mass index? Am J Epidemiol 1985;122:434-442.
5. Goldbourt U, Holtzman E, Cohen-Mandelzweig L, Neufeld HN., Enhanced risk of coronary heart disease mortality in lean hypertensive men. Hypertension 1987;10:22-28.
6. Stamler R, Ford CE, Stamler J., Why do lean hypertensives have higher mortality rates than other hypertensives? Findings of the Hypertension Detection and Follow-up Program. Hypertension 1991;17:553-564.
7. Selmer R, Tverdal A., Body mass index and cardiovascular mortality at different levels of blood pressure: A prospective study of Norwegian men and women. J Epidemiol Community Health 1995;49:265-270.
8. Bloom E, Reed D, Yano K, MacLean C., Does obesity protect hypertensives against cardiovascular diseases? JAMA 1986;256:2972-2975.
9. Bender R, Jöckel KH, Richter B, Spraul M, Berger M., Body weight, blood pressure, and mortality in a cohort of obese patients. Am J Epidemiol 2002;156:239-245.
10. Chrysant SG, Chrysant GS., New insights into the true nature of the obesity paradox and the lower cardiovascular risk. J Am Soc Hypertens 2013;7:85-94. doi: 10.1016/j.jash.2012.11.008
11. Cornier MA, Després JP, Davis N, Grossniklaus DA, Klein S, Lamarche B, Lopez-Jimenez F, Rao G, St-Onge MP, Towfighi A, Poirier P, American Heart Association Obesity Committee of the Council on Nutrition; Physical Activity and Metabolism; Council on Arteriosclerosis; Thrombosis and Vascular Biology; Council on Cardiovascular Disease in the Young; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing, Council on Epidemiology and Prevention; Council on the Kidney in Cardiovascular Disease, and Stroke Council Assessing adiposity: A scientific statement from the American Heart Association. Circulation 2011;124:1996-2019. doi: 10.1161/CIR.0b013e318233bc6a
12. Bild DE, Bluemke DA, Burke GL, Multi-ethnic study of atherosclerosis: Objectives and design. Am J Epidemiol 2002;156:871-881.
13. Gu D, He J, Duan X, Reynolds K, Wu X, Chen J, Huang G, Chen CS, Whelton PK., Body weight and mortality among men and women in China. JAMA 2006;295:776-783. doi: 10.1001/jama.295.7.776
14. Jensen MD, Ryan DH, Apovian CM, American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Obesity Society 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol 2014;63(25 pt B)2985-3023. doi: 10.1016/j.jacc.2013.11.004
15. World Health Organization Waist Circumference and Waist-Hip Ratio: Report of a WHO Expert Consultation, Geneva, 8-11 December 2008-2011, Geneva, Switzerland World Health Organization
16. Expert Consultation WHO; WHO Expert Consultation Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363:157-163.
17. Bittencourt MS, Blaha MJ, Blankstein R, Budoff M, Vargas JD, Blumenthal RS, Agatston AS, Nasir K., Polypill therapy, subclinical atherosclerosis, and cardiovascular events-implications for the use of preventive pharmacotherapy: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol 2014;63:434-443. doi: 10.1016/j.jacc.2013.08.1640
18. Li R, Chambless L., Test for additive interaction in proportional hazards models. Ann Epidemiol 2007;17:227-236. doi: 10.1016/j.annepidem.2006.10.009
19. de Koning L, Merchant AT, Pogue J, Anand SS., Waist circumference and waist-to-hip ratio as predictors of cardiovascular events: Meta-regression analysis of prospective studies. Eur Heart J 2007;28:850-856. doi: 10.1093/eurheartj/ehm026
20. Uretsky S, Messerli FH, Bangalore S, Champion A, Cooper-Dehoff RM, Zhou Q, Pepine CJ., Obesity paradox in patients with hypertension and coronary artery disease. Am J Med 2007;120:863-870. doi: 10.1016/j.amjmed.2007.05.011
21. Carman WJ, Barrett-Connor E, Sowers M, Khaw KT., Higher risk of cardiovascular mortality among lean hypertensive individuals in Tecumseh, Michigan. Circulation 1994;89:703-711.
22. Wassertheil-Smoller S, Fann C, Allman RM, Black HR, Camel GH, Davis B, Masaki K, Pressel S, Prineas RJ, Stamler J, Vogt TM., Relation of low body mass to death and stroke in the systolic hypertension in the elderly program. The SHEP Cooperative Research Group. Arch Intern Med 2000;160:494-500.
23. Banack HR, Kaufman JS., The obesity paradox: Understanding the effect of obesity on mortality among individuals with cardiovascular disease. Prev Med 2014;62:96-102. doi: 10.1016/j.ypmed.2014.02.003
24. Preston SH, Stokes A., Obesity paradox: Conditioning on disease enhances biases in estimating the mortality risks of obesity. Epidemiology 2014;25:454-461. doi: 10.1097/EDE.0000000000000075
25. Glymour MM, Vittinghoff E., Commentary: Selection bias as an explanation for the obesity paradox: Just because it's possible doesn't mean it's plausible. Epidemiology 2014;25:4-6. doi: 10.1097/EDE.0000000000000013
26. Greenland S., Quantifying biases in causal models: Classical confounding vs collider-stratification bias. Epidemiology 2003;14:300-306.
27. Hernán MA, Hernández-Díaz S, Robins JM., A structural approach to selection bias. Epidemiology 2004;15:615-625.
28. Silventoinen K, Magnusson PK, Neovius M, Sundström J, Batty GD, Tynelius P, Rasmussen F., Does obesity modify the effect of blood pressure on the risk of cardiovascular disease? A population-based cohort study of more than one million Swedish men. Circulation 2008;118:1637-1642. doi: 10.1161/CIRCULATIONAHA.108.772707
29. Mørkedal B, Romundstad PR, Vatten LJ., Mortality from ischaemic heart disease: Age-specific effects of blood pressure stratified by body-mass index: The HUNT cohort study in Norway. J Epidemiol Community Health 2011;65:814-819. doi: 10.1136/jech.2009.094110
30. Lavie CJ, McAuley PA, Church TS, Milani RV, Blair SN., Obesity and cardiovascular diseases: Implications regarding fitness, fatness, and severity in the obesity paradox. J Am Coll Cardiol 2014;63:1345-1354. doi: 10.1016/j.jacc.2014.01.022
31. McAuley PA, Beavers KM., Contribution of cardiorespiratory fitness to the obesity paradox. Prog Cardiovasc Dis 2014;56:434-440. doi: 10.1016/j.pcad.2013.09.006
32. Lambert E, Straznicky N, Schlaich M, Esler M, Dawood T, Hotchkin E, Lambert G., Differing pattern of sympathoexcitation in normal-weight and obesity-related hypertension. Hypertension 2007;50:862-868. doi: 10.1161/HYPERTENSIONAHA.107.094649
33. Padmanabhan S, Newton-Cheh C, Dominiczak AF., Genetic basis of blood pressure and hypertension. Trends Genet 2012;28:397-408. doi: 10.1016/j.tig.2012.04.001
34. Fava C, Sjögren M, Montagnana M, Danese E, Almgren P, Engström G, Nilsson P, Hedblad B, Guidi GC, Minuz P, Melander O., Prediction of blood pressure changes over time and incidence of hypertension by a genetic risk score in Swedes. Hypertension 2013;61:319-326. doi: 10.1161/HYPERTENSIONAHA.112.202655
35. Havulinna AS, Kettunen J, Ukkola O, Osmond C, Eriksson JG, Kesäniemi YA, Jula A, Peltonen L, Kontula K, Salomaa V, Newton-Cheh C., A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32,669 individuals. Hypertension 2013;61:987-994. doi: 10.1161/HYPERTENSIONAHA.111.00649
36. Joseph PG, Pare G, Anand SS., Exploring gene-environment relationships in cardiovascular disease. Can J Cardiol 2013;29:37-45. doi: 10.1016/j.cjca.2012.10.009
37. Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino RB Sr, O'Donnell CJ., Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the Framingham Heart Study. Circulation 2007;116:39-48. doi: 10.1161/CIRCULATIONAHA.106.675355
38. Britton KA, Fox CS., Ectopic fat depots and cardiovascular disease. Circulation 2011 124 e837 e841. doi: 10.1161/CIRCULATIONAHA.111.077602
39. Britton KA, Massaro JM, Murabito JM, Kreger BE, Hoffmann U, Fox CS., Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality. J Am Coll Cardiol 2013;62:921-925. doi: 10.1016/j.jacc.2013.06.027