The Social Value of Knowledge and International Clinical Research

Developing World Bioethics

Volumn 15, Issue 2, 2015, Pages 76-84

  Wenner, Danielle M ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Clinical trials; Developing world bioethics; International justice; Knowledge; Research ethics

Indexed keywords

CLINICAL TRIAL (TOPIC); DEVELOPING COUNTRY; DRUG INDUSTRY; ECONOMICS; ETHICS; GLOBAL HEALTH; HEALTH CARE DELIVERY; HUMAN; INTERNATIONAL COOPERATION; KNOWLEDGE; MEDICAL RESEARCH; NORMAL HUMAN; PARTICIPATORY RESEARCH; PERSONAL AUTONOMY; PROCEDURES; RESEARCH ETHICS; RESEARCH SUBJECT; SOCIAL JUSTICE; SOCIAL PSYCHOLOGY; STANDARDS; STATISTICS AND NUMERICAL DATA; TRENDS;

BIOMEDICAL RESEARCH; CLINICAL TRIALS AS TOPIC; COMMUNITY-BASED PARTICIPATORY RESEARCH; DEVELOPING COUNTRIES; DRUG INDUSTRY; ETHICS, RESEARCH; GLOBAL HEALTH; HEALTH SERVICES ACCESSIBILITY; HEALTHY VOLUNTEERS; HUMANS; INTERNATIONAL COOPERATION; KNOWLEDGE; PERSONAL AUTONOMY; RESEARCH SUBJECTS; SOCIAL JUSTICE; SOCIAL VALUES;

EID: 84937515709     PISSN: 14718731     EISSN: 14718847     Source Type: Journal    
DOI: 10.1111/dewb.12037     Document Type: Article

References (23)

1. A. Petryna 2009. When Experiments Travel: Clinical Trials and the Global Search for Human Subjects. Princeton: Princeton University Press: 13.
2. G.M. Lairumbi etal. Ethics in Practice: The State of the Debate on Promoting the Social Value of Global Health Research in Resource Poor Settings Particularly Africa. BMC Med Ethics 2011; 12(22).
3. Council for International Organizations of Medical Sciences (CIOMS). 2002. International Ethical Guidelines for Biomedical Research Involving Human Subjects. Geneva: CIOMS. Available at: http://www.cioms.ch/publications/guidelines/guidelines_nov_2002_blurb.htm [Accessed 15 Sept 2013]; World Medical Association (WMA). 2008. Declaration of Helsinki. Ferney-Voltaire, France: WMA. Available at: http://www.wma.net/en/30publications/10policies/b3/17c.pdf [Accessed 15 Sept 2013].
4. D. Schroeder & E. Gefenas Realizing Benefit Sharing - The Case of Post-Study Obligations. Bioethics 2012; 26: 305-314.
5. Participants in the 2001 Conference on Ethical Aspects of Research in Developing Countries. Fair benefits for research in developing countries. Science 2002; 298: 2133-2134: 2134.
6. See, for example, A. Wertheimer 2008. Exploitation in Clinical Research. In Exploitation and Developing Countries: The Ethics of Clinical Research, J.S. Hawkins & E.J. Emanuel, eds. Princeton: Princeton University Press: 63-104.
7. A.G. Mitra Off-Shoring Clinical Research: Exploitation and the Reciprocity Constraint. Dev World Bioeth 2012: Epub Ahead of Print.
8. A.J. London & K.J.S. Zollman Research at the Auction Block: Problems for the Fair Benefits Approach to International Research. Hastings Cent Rep 2010; 40(4): 34-45.
9. T. Pogge 2008. Testing Our Drugs on the Poor Abroad. In Exploitation and Developing Countries: The Ethics of Clinical Research, J.S. Hawkins & E.J. Emanuel, eds. Princeton: Princeton University Press: 105-141.
10. A.J. London Justice and the Human Development Approach to International Research. Hastings Cent Rep 2005; 35(1): 24-37: 33.
11. P.S. Appelbaum, L.H. Roth & C.W. Lidz The Therapeutic Misconception: Informed Consent in Psychiatric Research. Int J Law Psychiatry 1982; 5: 319-329; P.S. Appelbaum, C.W. Lidz & T. Grisso Therapeutic Misconception in Clinical Research: Frequency and Risk Factors. IRB 2004; 26(2): 1-8.
12. B. Pratt & B. Loff Justice in International Clinical Research. Dev World Bioeth 2011; 11(2): 75-81.
13. H.E. Douglas 2009. Science, Policy, and the Value-Free Ideal. Pittsburgh, PA: University of Pittsburgh Press: 89-95.
14. 1949. The Nuremberg Code. In Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law No. 10. Nuremberg, October 1946-April 1949. Washington, DC: USGPO.
15. S. Joffe & F.G. Miller Bench to bedside: Mapping the moral terrain of clinical research. Hastings Cent Rep 2008; 38(2): 30-42
16. C. Grady Science in the Service of Healing. Hastings Cent Rep 1998; 28(6): 34-38
17. E.J. Emanuel, D. Wendler & C. Grady What makes clinical research ethical? JAMA 2000; 283: 2701-2711.
18. J. Rawls 1971. A Theory of Justice. Cambridge, MA: Harvard University Press: 432.
19. J. Kimmelman 2010. Gene Transfer and the Ethics of First-in-Human Research: Lost in Translation. Cambridge, MA: Cambridge University Press: 92-97.
20. A. Wertheimer 2011. Rethinking the ethics of clinical research: Widening the lens. Oxford, England: Oxford University Press: 213-223.
21. J. Andrews Research in the Ranks: Vulnerable Subjects, Coercible Collaboration, and the Hepatitis E Vaccine Trial in Nepal. Perspect Biol Med 2006; 49: 35-51.
22. E. Abraham etal. Drotrecogin Alfa (Activated) for Adults with Severe Sepsis and a Low Risk of Death. N Engl J Med 2005; 353(13):1332-1341.
23. See, for example, P. Kitcher Scientific Research - Who Should Govern? NanoEthics 2007; 1: 177-184.