Valproic Acid Attenuates Acute Lung Injury Induced by Ischemia-Reperfusion in Rats

Anesthesiology

Volumn 122, Issue 6, 2015, Pages 1327-1337

  Wu, Shu Yu ^a   Tang, Shih En ^b   Ko, Fu Chang ^c   Wu, Geng Chin ^c   Huang, Kun Lun ^a,b   Chu, Shi Jye ^b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c TAOYUAN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; HISTONE H3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; PROTOPORPHYRIN ZINC; TUMOR NECROSIS FACTOR ALPHA; VALPROIC ACID; ANTIOXIDANT; HISTONE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; INFLAMMATION; LUNG ARTERY PRESSURE; LUNG EDEMA; LUNG LAVAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; ACETYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BODY WEIGHT; CAPILLARY PERMEABILITY; COMPLICATION; DRUG EFFECTS; METABOLISM; ORGAN SIZE; PATHOLOGY; PROTEIN CARBONYLATION; PULMONARY EDEMA; SPRAGUE DAWLEY RAT;

ACETYLATION; ACUTE LUNG INJURY; ANIMALS; ANTIOXIDANTS; BODY WEIGHT; CAPILLARY PERMEABILITY; HEME OXYGENASE-1; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITORS; HISTONES; INFLAMMATION; MALE; ORGAN SIZE; PROTEIN CARBONYLATION; PULMONARY EDEMA; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; VALPROIC ACID;

EID: 84937512344     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000618     Document Type: Article

References (29)

1. Dinarello CA, Fossati G, Mascagni P: Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer. Mol Med 2011; 17:333-52
2. Halili MA, Andrews MR, Sweet MJ, Fairlie DP: Histone deacetylase inhibitors in inflammatory disease. Curr Top Med Chem 2009; 9:309-19
3. Li Y, Alam HB: Modulation of acetylation: Creating a pro-survival and anti-inflammatory phenotype in lethal hemorrhagic and septic shock. J Biomed Biotechnol 2011; 2011:523481
4. Fukudome EY, Li Y, Kochanek AR, Lu J, Smith EJ, Liu B, Kim K, Velmahos GC, deMoya MA, Alam HB: Pharmacologic resuscitation decreases circulating cytokine-induced neutrophil chemoattractant-1 levels and attenuates hemorrhageinduced acute lung injury. Surgery 2012; 152:254-61
5. Ni YF, Wang J, Yan XL, Tian F, Zhao JB, Wang YJ, Jiang T: Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice. Respir Res 2010; 11:33
6. Kim K, Li Y, Jin G, Chong W, Liu B, Lu J, Lee K, Demoya M, Velmahos GC, Alam HB: Effect of valproic acid on acute lung injury in a rodent model of intestinal ischemia reperfusion. Resuscitation 2012; 83:243-8
7. Wu SY, Li MH, Ko FC, Wu GC, Huang KL, Chu SJ: Protective effect of hypercapnic acidosis in ischemia-reperfusion lung injury is attributable to upregulation of heme oxygenase-1. PLoS One 2013; 8:e74742
8. Chu SJ, Chang DM, Wang D, Chen YH, Hsu CW, Hsu K: Fructose-1,6-diphosphate attenuates acute lung injury induced by ischemia-reperfusion in rats. Crit Care Med 2002; 30:1605-9
9. Peng CK, Huang KL, Wu CP, Li MH, Hu YT, Hsu CW, Tsai SH, Chu SJ: Glutamine protects ischemia-reperfusion induced acute lung injury in isolated rat lungs. Pulm Pharmacol Ther 2011; 24:153-61
10. Chang H, Li MH, Chen CW, Yan HC, Huang KL, Chu SJ: Intravascular FC-77 attenuates phorbol myristate acetateinduced acute lung injury in isolated rat lungs. Crit Care Med 2008; 36:1222-9
11. Tang SE, Wu CP, Wu SY, Peng CK, Perng WC, Kang BH, Chu SJ, Huang KL: Stanniocalcin-1 ameliorates lipopolysaccharide-induced pulmonary oxidative stress, inflammation, and apoptosis in mice. Free Radic Biol Med 2014; 71:321-31
12. Wu SY, Wu CP, Kang BH, Li MH, Chu SJ, Huang KL: Hypercapnic acidosis attenuates reperfusion injury in isolated and perfused rat lungs. Crit Care Med 2012; 40:553-9
13. Kochanek AR, Fukudome EY, Li Y, Smith EJ, Liu B, Velmahos GC, deMoya M, King D, Alam HB: Histone deacetylase inhibitor treatment attenuates MAP kinase pathway activation and pulmonary inflammation following hemorrhagic shock in a rodent model. J Surg Res 2012; 176:185-94
14. Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, Chuang DM: Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: Multiple mechanisms of action. J Pharmacol Exp Ther 2007; 321:892-901
15. Williams AE, Chambers RC: The mercurial nature of neutrophils: Still an enigma in ARDS? Am J Physiol Lung Cell Mol Physiol 2014; 306:L217-30
16. Adkins WK, Taylor AE: Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung. J Appl Physiol (1985) 1990; 69:2012-8
17. Ximenes JC, de Oliveira Gonçalves D, Siqueira RM, Neves KR, Santos Cerqueira G, Correia AO, Félix FH, Leal LK, de Castro Brito GA, da Graça Naffah-Mazzacorati M, Viana GS: Valproic acid: An anticonvulsant drug with potent antinociceptive and anti-inflammatory properties. Naunyn Schmiedebergs Arch Pharmacol 2013; 386:575-87
18. McCord JM: Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985; 312:159-63
19. Zhang Z, Qin X, Zhao X, Tong N, Gong Y, Zhang W, Wu X: Valproic acid regulates antioxidant enzymes and prevents ischemia/reperfusion injury in the rat retina. Curr Eye Res 2012; 37:429-37
20. de Perrot M, Liu M, Waddell TK, Keshavjee S: Ischemiareperfusion-induced lung injury. Am J Respir Crit Care Med 2003; 167:490-511
21. Faraco G, Pancani T, Formentini L, Mascagni P, Fossati G, Leoni F, Moroni F, Chiarugi A: Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain. Mol Pharmacol 2006; 70:1876-84
22. Ghizzoni M, Haisma HJ, Maarsingh H, Dekker FJ: Histone acetyltransferases are crucial regulators in NF-B mediated inflammation. Drug Discov Today 2011; 16:504-11
23. Lührs H, Gerke T, Müller JG, Melcher R, Schauber J, Boxberge F, Scheppach W, Menzel T: Butyrate inhibits NF-B activation in lamina propria macrophages of patients with ulcerative colitis. Scand J Gastroenterol 2002; 37:458-66
24. Xie M, Kong Y, Tan W, May H, Battiprolu PK, Pedrozo Z, Wang ZV, Morales C, Luo X, Cho G, Jiang N, Jessen ME, Warner JJ, Lavandero S, Gillette TG, Turer AT, Hill JA: Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation 2014; 129:1139-51
25. Xu B, Gao X, Xu J, Lei S, Xia ZY, Xu Y, Xia Z: Ischemic postconditioning attenuates lung reperfusion injury and reduces systemic proinflammatory cytokine release via heme oxygenase. J Surg Res 2011; 166:e157-64
26. Zhang X, Shan P, Jiang D, Noble PW, Abraham NG, Kappas A, Lee PJ: Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. J Biol Chem 2004; 279:10677-84
27. Kessler-Icekson G, Hochhauser E, Sinai T, Kremer A, Dick J, Tarasenko N, Nudelman V, Schlesinger H, Abraham S, Nudelman A, Rephaeli A: A histone deacetylase inhibitory prodrug-butyroyloxymethyl diethyl phosphate-protects the heart and cardiomyocytes against ischemia injury. Eur J Pharm Sci 2012; 45:592-9
28. Wang B, Zhu X, Kim Y, Li J, Huang S, Saleem S, Li RC, Xu Y, Dore S, Cao W: Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage. Free Radic Biol Med 2012; 52:928-36
29. Shakespear MR, Hohenhaus DM, Kelly GM, Kamal NA, Gupta P, Labzin LI, Schroder K, Garceau V, Barbero S, Iyer A, Hume DA, Reid RC, Irvine KM, Fairlie DP, Sweet MJ: Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages. J Biol Chem 2013; 288:25362-74