A lipid switch unlocks Parkinson's disease-associated ATP13A2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 29, 2015, Pages 9040-9045

  Holemans, Tine ^a   Sørensen, Danny Mollerup ^a   Van Veen, Sarah ^a   Martin, Shaun ^a   Hermans, Diane ^a   Kemmer, Gerdi Christine ^b   Van Den Haute, Chris ^c,d   Baekelandt, Veerle ^c   Pomorski, Thomas Günther ^b   Agostinis, Patrizia ^a   Wuytack, Frank ^a   Palmgren, Michael ^b   Eggermont, Jan ^a   Vangheluwe, Peter ^a  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d KU LEUVEN   (Belgium)

Author keywords

Lysosome|flippase; Mitochondria; P5 type ATPase; synuclein

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE ATP13A2; ALPHA SYNUCLEIN; GLYCEROPHOSPHOLIPID; LIPID; PHOSPHATIDIC ACID; PHOSPHATIDYLINOSITOL(3,5)BISPHOSPHATE; ROTENONE; UNCLASSIFIED DRUG; ATP13A2 PROTEIN, HUMAN; GREEN FLUORESCENT PROTEIN; MANGANESE; PHOSPHATIDYLINOSITOL 3,5-DIPHOSPHATE; POLYPHOSPHOINOSITIDE; PROTEIN BINDING; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; ZINC;

ARTICLE; AUTOPHOSPHORYLATION; CATALYST; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROPHOBICITY; LYSOSOME; LYSOSOME MEMBRANE; MEMBRANE LEAFLET; PARKINSON DISEASE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SURFACE PROPERTY; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOSOL; DRUG EFFECTS; ENDOSOME; GENETICS; METABOLISM; MITOCHONDRION; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; CELL LINE; CELL MEMBRANE; CYTOSOL; ENDOSOMES; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LIPIDS; LYSOSOMES; MANGANESE; MITOCHONDRIA; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PARKINSON DISEASE; PHOSPHATIDIC ACIDS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PROTEIN BINDING; PROTON-TRANSLOCATING ATPASES; STRUCTURAL HOMOLOGY, PROTEIN; ZINC;

EID: 84937510991     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1508220112     Document Type: Article

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