Complex formation between two biosynthetic enzymes modifies the allosteric regulatory properties of both: An example of molecular symbiosis

Journal of Biological Chemistry

Volumn 290, Issue 29, 2015, Pages 18187-18198

  Blackmore, Nicola J ^a   Nazmi, Ali Reza ^a   Hutton, Richard D ^a   Webby, Melissa N ^a   Baker, Edward N ^b   Jameson, Geoffrey B ^c   Parker, Emily J ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; AROMATIC COMPOUNDS; BIOCHEMISTRY; BIOSYNTHESIS; CATALYST ACTIVITY; MACHINERY;

ANALYTICAL ULTRACENTRIFUGATION; AROMATIC AMINO ACID; BIOSYNTHETIC ENZYMES; COMPLEX DISSOCIATION; COMPLEX FORMATIONS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN FUNCTIONS; REGULATORY PROPERTIES;

ENZYMES;

3 DEOXY 7 PHOSPHOHEPTULONATE SYNTHASE; CHORISMATE MUTASE; PHENYLALANINE; TYROSINE; AROMATIC AMINO ACID;

ALLOSTERISM; AMINO ACID SYNTHESIS; ARTICLE; BINDING SITE; COMPLEX FORMATION; DISSOCIATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME MECHANISM; MOLECULAR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SEDIMENTATION; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; MICROBIOLOGY; PROTEIN MULTIMERIZATION; TUBERCULOSIS; X RAY CRYSTALLOGRAPHY;

MYCOBACTERIUM TUBERCULOSIS;

3-DEOXY-7-PHOSPHOHEPTULONATE SYNTHASE; ALLOSTERIC REGULATION; AMINO ACIDS, AROMATIC; CHORISMATE MUTASE; CRYSTALLOGRAPHY, X-RAY; HUMANS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN MULTIMERIZATION; TUBERCULOSIS;

EID: 84937501220     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.638700     Document Type: Article

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