Three sites and you are out: Ternary synergistic allostery controls aromatic amino acid biosynthesis in mycobacterium tuberculosis

Journal of Molecular Biology

Volumn 425, Issue 9, 2013, Pages 1582-1592

  Blackmore, Nicola J ^a   Reichau, Sebastian ^a   Jiao, Wanting ^a   Hutton, Richard D ^a   Baker, Edward N ^b   Jameson, Geoffrey B ^c   Parker, Emily J ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

3 deoxy d arabino heptulosonate 7 phosphate synthase; allosteric regulation; mutagenesis; Mycobacterium tuberculosis; shikimate pathway

Indexed keywords

ENZYME; PHENYLALANINE; TRYPTOPHAN; TYROSINE;

ALLOSTERISM; ARTICLE; BINDING SITE; BIOSYNTHESIS; ISOTHERMAL TITRATION CALORIMETRY; MUTAGENESIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84876409727     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.12.019     Document Type: Article

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