Neuropsychological Outcome of Children Treated for Standard Risk Medulloblastoma in the PNET4 European Randomized Controlled Trial of Hyperfractionated Versus Standard Radiation Therapy and Maintenance Chemotherapy

International Journal of Radiation Oncology Biology Physics

Volumn 92, Issue 5, 2015, Pages 978-985

  Câmara Costa, Hugo ^a   Resch, Anika ^b   Kieffer, Virginie ^c   Lalande, Clémence ^d   Poggi, Geraldina ^e   Kennedy, Colin ^f   Bull, Kim ^f   Calaminus, Gabriele ^g   Grill, Jacques ^d   Doz, François ^h   Rutkowski, Stefan ^b   Massimino, Maura ⁱ   Kortmann, Rolf Dieter ^j   Lannering, Birgitta ^k   Dellatolas, Georges ^a   Chevignard, Mathilde ^l  

^a INSERM U1178   (France)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Saint Maurice National Hospital   (France)

^d INSTITUT GUSTAVE ROUSSY   (France)

^e SCIENTIFIC INSTITUTE   (Italy)

^f UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^g UNIVERSITY OF MÜNSTER   (Germany)

^h UNIVERSITÉ PARIS DESCARTES   (France)

ⁱ NATIONAL CANCER INSTITUTE   (Italy)

^j UNIVERSITY OF LEIPZIG   (Germany)

^k UNIVERSITY OF GOTHENBURG   (Sweden)

^l SORBONNE UNIVERSITÉ   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CHEMOTHERAPY; RADIOTHERAPY; SURVEYS;

COGNITIVE ABILITY; CONFIDENCE INTERVAL; EXECUTIVE FUNCTION; INTELLIGENCE QUOTIENTS; METHODS AND MATERIALS; NEUROPSYCHOLOGICAL; PERFORMANCE BASED; RANDOMIZED CONTROLLED TRIAL;

DIAGNOSIS;

ANTINEOPLASTIC AGENT; CISPLATIN; LOMUSTINE; VINCRISTINE;

ADOLESCENT; ADULT; ARTICLE; CANCER PATIENT; CANCER RADIOTHERAPY; CHILD; CHILDHOOD CANCER; CLINICAL ASSESSMENT; COGNITION; CONFIDENCE INTERVAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; EVENT FREE SURVIVAL; EYE MOVEMENT DISORDER; FEMALE; FULL SCALE INTELLIGENCE QUOTIENT; HUMAN; HYPERFRACTIONATED RADIATION THERAPY; INTELLIGENCE; INTELLIGENCE QUOTIENT; MAINTENANCE CHEMOTHERAPY; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; MUTISM; NEUROPSYCHOLOGICAL TEST; NEUROPSYCHOLOGY; NEUROSURGERY; PERFORMANCE INTELLIGENCE QUOTIENT; PRIORITY JOURNAL; PROCESSING SPEED INDEX; PROSPECTIVE STUDY; PSYCHOLOGIC TEST; RADIATION DOSE FRACTIONATION; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; STANDARD RADIATION THERAPY; TREATMENT DURATION; TREATMENT OUTCOME; TREND STUDY; VERBAL INTELLIGENCE QUOTIENT; WECHSLER INTELLIGENCE SCALE; WORKING MEMORY; WORKING MEMORY INDEX; AGE; ANALYSIS OF VARIANCE; CEREBELLAR NEOPLASMS; COGNITIVE DEFECT; CRANIOSPINAL IRRADIATION; DRUG EFFECTS; EUROPE; EXECUTIVE FUNCTION; INTELLIGENCE TEST; MEMORY; PHYSIOLOGY; PRESCHOOL CHILD; PROCEDURES; PSYCHOLOGY; RADIATION RESPONSE; REGRESSION ANALYSIS; YOUNG ADULT;

ADOLESCENT; AGE FACTORS; ANALYSIS OF VARIANCE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; CISPLATIN; COGNITION; COGNITION DISORDERS; CONFIDENCE INTERVALS; CRANIOSPINAL IRRADIATION; DOSE FRACTIONATION; EUROPE; EXECUTIVE FUNCTION; FEMALE; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; LOMUSTINE; MAINTENANCE CHEMOTHERAPY; MALE; MEDULLOBLASTOMA; MEMORY; PROSPECTIVE STUDIES; REGRESSION ANALYSIS; VINCRISTINE; YOUNG ADULT;

EID: 84937469056     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2015.04.023     Document Type: Article

References (40)

1. G.T. Armstrong Long-term survivors of childhood central nervous system malignancies: The experience of the Childhood Cancer Survivor Study Eur J Paediatr Neurol 14 2010 298 303
2. F. Bartlett, R. Kortmann, and F. Saran Medulloblastoma Clin Oncol 25 2013 36 45
3. K.K. Boman, E. Hovén, M. Anclair, and et al. Health and persistent functional late effects in adult survivors of childhood CNS tumours: A population-based cohort study Eur J Cancer 45 2009 2552 2561
4. A.L. Ogilvy-Stuart, and S.M. Shalet Growth and puberty after growth hormone treatment after irradiation for brain tumours Arch Dis Child 73 1995 141 146
5. M. Schmiegelow Endocrinological late effects following radiotherapy and chemotherapy of childhood brain tumours Dan Med Bull 53 2006 326 341
6. E. Vázquez, A. Castellote, J. Piqueras, and et al. Second malignancies in pediatric patients: Imaging findings and differential diagnosis Radiographics 23 2003 1155 1172
7. D.A. Walker, J. Pillow, K.D. Waters, and et al. Enhanced cis-platinum ototoxicity in children with brain tumours who have received simultaneous or prior cranial irradiation Med Pediatr Oncol 17 1989 48 52
8. P. Frange, C. Alapetite, G. Gaboriaud, and et al. From childhood to adulthood: Long-term outcome of medulloblastoma patients. The Institut Curie experience (1980-2000) J Neurooncol 95 2009 271 279
9. A.M. Maddrey, J.A. Bergeron, E.R. Lombardo, and et al. Neuropsychological performance and quality of life of 10-year survivors of childhood medulloblastoma J Neurooncol 72 2005 245 253
10. K. Ribi, C. Relly, M.A. Landolt, and et al. Outcome of medulloblastoma in children: Long-term complications and quality of life Neuropediatrics 36 2005 357 365
11. D.J. Mabbott Diffusion tensor imaging of white matter after cranial radiation in children for medulloblastoma: Correlation with IQ Neuro Oncol 8 2006 244 252
12. R.K. Mulhern, S.L. Palmer, W.E. Reddick, and et al. Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss J Clin Oncol 19 2001 472 479
13. M. Benesch, K. Spiegl, A. Winter, and et al. A scoring system to quantify late effects in children after treatment for medulloblastoma/ependymoma and its correlation with quality of life and neurocognitive functioning Childs Nerv Syst 25 2009 173 181
14. R.W. Butler, and D.R. Copeland Attentional processes and their remediation in children treated for cancer: A literature review and the development of a therapeutic approach J Int Neuropsychol 8 2002 115 124
15. S.L. Palmer, O. Goloubeva, W.E. Reddick, and et al. Patterns of intellectual development among survivors of pediatric medulloblastoma: A longitudinal analysis J Clin Oncol 19 2001 2302 2308
16. B.J. Spiegler, E. Bouffet, M.L. Greenberg, and et al. Change in neurocognitive functioning after treatment with cranial radiation in childhood J Clin Oncol 22 2004 706 713
17. R.K. Mulhern, T.E. Merchant, A. Gajjar, and et al. Late neurocognitive sequelae in survivors of brain tumours in childhood Lancet Oncol 5 2004 399 408
18. S.L. Palmer, C. Armstrong, A. Onar-Thomas, and et al. Processing speed, attention, and working memory after treatment for medulloblastoma: An international, prospective, and longitudinal study J Clin Oncol 31 2013 3494 3500
19. J.F. Fowler Review: Total doses in fractionated radiotherapy-implications of new radiobiological data Int J Radiat Biol Relat Stud Phys Chem Med 46 1984 103 120
20. J.C. Allen, B. Donahue, R. DaRosso, and et al. Hyperfractionated craniospinal radiotherapy and adjuvant chemotherapy for children with newly diagnosed medulloblastoma and other primitive neuroectodermal tumors Int J Radiat Oncol Biol Phys 36 1996 1155 1161
21. M.D. Prados, M.S. Edwards, S.M. Chang, and et al. Hyperfractionated craniospinal radiation therapy for primitive neuroectodermal tumors: Results of a Phase II study Int J Radiat Oncol Biol Phys 43 1999 279 285
22. C. Carrie, J. Grill, D. Figarella-Branger, and et al. Online quality control, hyperfractionated radiotherapy alone and reduced boost volume for standard risk medulloblastoma: Long-term results of MSFOP 98 J Clin Oncol 27 2009 1879 1883
23. T. Gupta, R. Jalali, S. Goswami, and et al. Early clinical outcomes demonstrate preserved cognitive function in children with average-risk medulloblastoma when treated with hyperfractionated radiation therapy Int J Radiat Oncol Biol Phys 83 2012 1534 1540
24. B. Lannering, S. Rutkowski, F. Doz, and et al. Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standardrisk medulloblastoma: Results from the randomized multicenter HIT-SIOP PNET 4 trial J Clin Oncol 30 2012 187 3193
25. C. Kennedy, K. Bull, M. Chevignard, and et al. Quality of survival and growth in children and young adults in the PNET4 European controlled trial of hyperfractionated versus conventional radiation therapy for standard-risk medulloblastoma Int J Radiat Oncol Biol Phys 88 2014 292 300
26. D. Wechsler The Wechsler Intelligence Scale For Children 3rd ed. 1991 The Psychological Corp San Antonio, TX
27. D. Wechsler Wechsler Intelligence Scale for Children 4th ed. 2003 Harcourt Assessment, Inc San Antonio, TX
28. D. Wechsler Wechsler Adult Intelligence Scale 3rd ed. 1997 The Psychological Corp San Antonio, TX
29. D. Wechsler Wechsler Adult Intelligence Scale 4th ed. 2008 Pearson San Antonio, TX
30. J. Raven, J.C. Raven, and J.H. Court Manual for Raven's Progressive Matrices and Vocabulary Scales. Section 2: The Colored Progressive Matrices 1998 Oxford Psychologists Press/San Antonio, TX Oxford, England The Psychological Corp
31. J. Raven, J.C. Raven, and J.H. Court Manual for Raven's Progressive Matrices and Vocabulary Scales. Section 3: The Standard Progressive Matrices 1998 Oxford Psychologists Press/San Antonio, TX Oxford, England The Psychological Corp
32. A.S. Kaufman, and N.L. Kaufman Kaufman Assessment Battery For Children 2nd ed. 2004 American Guidance Service Circle Pines, MN
33. A. Glaser, C. Kennedy, J. Punt, and et al. Standardized quantitative assessment of brain tumor survivors treated within clinical trials in childhood Int J Cancer 12 1999 77 82
34. J.A. Limond, C.R. Kennedy, K.S. Bull, and et al. Quality of survival assessment in European childhood brain tumour trials, for children aged 5 and over Eur J Paediatr Neurol 19 2015 202 210
35. J. Grill, V.K. Renaux, C. Bulteau, and et al. Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes Int J Radiat Oncol Biol Phys 45 1999 137 145
36. W.E. Reddick, H.A. White, J.O. Glass, and et al. Developmental model relating white matter volume to neurocognitive deficits in pediatric brain tumor survivors Cancer 97 2003 2512 2519
37. S.L. Palmer Neurodevelopmental impacts on children treated for medulloblastoma: A review and proposed conceptual model Dev Dis Res Rev 14 2008 201 210
38. T.E. Merchant, L.E. Kun, M.J. Krasin, and et al. Multi-institution prospective trial of reduced-dose craniospinal irradiation (23.4 Gy) followed by conformal posterior fossa (36 Gy) and primary site irradiation (55.8 Gy) and dose-intensive chemotherapy for average-risk medulloblastoma Int J Radiat Oncol Biol Phys 70 2007 782 787
39. E.R. Vriezen, and S.E. Pigott The relationship between parental report on the BRIEF and performance-based measures of executive function in children with moderate to severe traumatic brain injury Child Neuropsychol 8 2002 296 303
40. M.P. Chevignard, C. Soo, J. Galvin, and et al. Ecological assessment of cognitive functions in children with acquired brain injury: A systematic review Brain Inj 26 2012 1033 1057