Quality of survival and growth in children and young adults in the PNET4 European controlled trial of hyperfractionated versus conventional radiation therapy for standard-risk medulloblastoma

International Journal of Radiation Oncology Biology Physics

Volumn 88, Issue 2, 2014, Pages 292-300

  Kennedy, Colin ^a,m   Bull, Kim ^a   Chevignard, Mathilde ^b,c   Culliford, David ^a   Dörr, Helmuth G ^d   Doz, François ^e   Kortmann, Rolf Dieter ^f   Lannering, Birgitta ^g   Massimino, Maura ^h   Navajas Gutiérrez, Aurora ⁱ   Rutkowski, Stefan ^j   Spoudeas, Helen A ^k   Calaminus, Gabriele ^l  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b Saint Maurice Hospitals   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f UNIVERSITY OF LEIPZIG   (Germany)

^g UNIVERSITY OF GOTHENBURG   (Sweden)

^h NATIONAL CANCER INSTITUTE   (Italy)

ⁱ HOSPITAL DE CRUCES   (Spain)

^j UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^k UNIVERSITY COLLEGE LONDON   (United Kingdom)

^l UNIVERSITY OF MÜNSTER   (Germany)

^m SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL NERVOUS SYSTEMS; CONFIDENCE INTERVAL; CONVENTIONAL RADIATION THERAPY; EXECUTIVE FUNCTION; HEALTH-RELATED QUALITY OF LIVES; HEARING IMPAIRMENTS; METHODS AND MATERIALS; SURVIVAL AND GROWTH;

AUDITION; BRAIN; CHEMOTHERAPY; DIAGNOSIS; HEALTH; RADIOTHERAPY; SURVEYS;

QUALITY CONTROL;

CISPLATIN; VINCRISTINE;

ADOLESCENT; ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RISK; CANCER SURVIVAL; CANCER SURVIVOR; CHILD; CONTROLLED CLINICAL TRIAL (TOPIC); CONVENTIONAL RADIATION THERAPY; EXECUTIVE FUNCTION; FEMALE; GROWTH; HEALTH BEHAVIOR; HEALTH STATUS; HEARING IMPAIRMENT; HUMAN; HYPERFRACTIONATED; LANGUAGE; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; PRESCHOOL CHILD; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RADIATION DOSE FRACTIONATION; SCHOOL CHILD; SCORING SYSTEM; YOUNG ADULT;

ADOLESCENT; AGE FACTORS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BEHAVIOR; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; COMBINED MODALITY THERAPY; DOSE FRACTIONATION; EMPLOYMENT; EUROPE; EXECUTIVE FUNCTION; FEMALE; FOLLOW-UP STUDIES; GROWTH; HEALTH STATUS; HEARING; HORMONE REPLACEMENT THERAPY; HUMANS; MALE; MEDULLOBLASTOMA; OUTCOME ASSESSMENT (HEALTH CARE); QUALITY OF LIFE; QUESTIONNAIRES; SURVIVORS; YOUNG ADULT;

EID: 84891869161     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.09.046     Document Type: Article

References (50)

1. G.T. Armstrong, N. Jain, and W. Liu et al. Region-specific radiotherapy and neuropsychological outcomes in adult survivors of childhood CNS malignancies Neuro Oncol 12 2010 1173 1186
2. K.K. Boman, F. Lindblad, and A. Hjern Long-term outcomes of childhood cancer survivors in Sweden: A population-based study of education, employment, and income Cancer 116 2010 1385 1391
3. M. Vinchon, M. Baroncini, and P. Leblond et al. Morbidity and tumor-related mortality among adult survivors of pediatric brain tumors: A review Childs Nervous System 27 2011 697 704
4. G.T. Armstrong Long-term survivors of childhood central nervous system malignancies: The experience of the Childhood Cancer Survivor Study Eur J Paediatr Neurol 14 2010 298 303
5. K.K. Boman, E. Hoven, and M. Andclair et al. Health and persistent functional late effects in adult survivors of childhood CNS tumours: A population-based cohort study Eur J Cancer 45 2009 2552 2561
6. P. Frange, C. Alapetite, and G. Gaboriaud et al. From childhood to adulthood: Long-term outcome of medulloblastoma patients. The Institut Curie experience (1980-2000) J Neurooncol 95 2009 271 279
7. K. Ribi, C. Relly, and M.A. Landolt et al. Outcome of medulloblastoma in children: Long-term complications and quality of life Neuropediatrics 36 2005 357 365 (Pubitemid 43162346)
8. A.M. Maddrey, J.A. Bergeron, and E.R. Lombardo et al. Neuropsychological performance and quality of life of 10 year survivors of childhood medulloblastoma J Neurooncol 72 2005 245 253 (Pubitemid 40867408)
9. R.K. Mulhern, T.E. Merchant, and A. Gajjar et al. Late neurocognitive sequelae in survivors of brain tumours in childhood Lancet Oncol 5 2004 399 408 (Pubitemid 38878043)
10. K.R. Wolfe, A. Madan-Swain, and R.K. Kana Executive dysfunction in pediatric posterior fossa tumor survivors: A systematic literature review of neurocognitive deficits and interventions Dev Neuropsychol 37 2012 153 175
11. L. Ellenberg, Q. Liu, and G. Gioia et al. Neurocognitive status in long-term survivors of childhood CNS malignancies: A report from the Childhood Cancer Survivor Study Neuropsychology 23 2009 705 717
12. E. Vaquero, C.M. Gomez, and E.A. Quintero et al. Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor Behav Brain Functions 4 2008 18
13. R.K. Mulhern, S.L. Palmer, and T.E. Merchant et al. Neurocognitive consequences of risk-adapted therapy for childhood medulloblastoma J Clin Oncol 23 2005 5511 5519
14. B.L. Pettorini, A. Narducci, and A. de Carlo et al. Thyroid neoplasm after central nervous system irradiation for medulloblastoma in childhood: Report of two cases Childs Nerv Syst 25 2009 631 634
15. A.L. Ogilvy-Stuart, and S.M. Shalet Growth and puberty after growth hormone treatment after irradiation for brain tumours Arch Dis Childhood 73 1995 141 146
16. A.L. Ogilvy-Stuart, S.M. Shalet, and H.R. Gattamaneni Thyroid function after treatment of brain tumors in children J Pediatr 119 1991 733 737
17. W.F. Hartsell, W.R. Hanson, and D.J. Conterato et al. Hyperfractionation decreases the deleterious effects of conventional radiation fractionation on vertebral growth in animals Cancer 63 1989 2452 2455 (Pubitemid 19152754)
18. H.A. Spoudeas Growth following malignancy Best Pract Res Clin Endocrinol Metab 16 2002 561 590
19. J.G. Gurney, N.S. Kadan-Lottick, and R.J. Packer et al. Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors - Childhood Cancer Survivor Study Cancer 97 2003 663 673 (Pubitemid 36125844)
20. Y. Grenier, T. Tomita, and M.H. Marymont et al. Late postirradiation occlusive vasculopathy in childhood medulloblastoma - report of two cases J Neurosurg 89 1998 460 464 (Pubitemid 28405262)
21. C.O. Maher, and C. Raffel Early vasculopathy following radiation in a child with medulloblastoma Pediatr Neurosurg 32 2000 255 258
22. I.S.M. Salih, N.J.N. Higgins, and E.A. Warburton et al. Lacunar stroke attributable to radiation-induced intracranial arteriopathy Eur J Neurol 14 2007 937 939 (Pubitemid 47106759)
23. L. Amoroso, J. Grill, and R. Bhangoo et al. High rate of second tumors in medulloblastoma long-term survivors in the cohort "the first 100" of the Gustave Roussy Institute Neuro Oncol 10 2008 475-475
24. K. Edelstein, B.J. Spiegler, and S. Fung et al. Early aging in adult survivors of childhood medulloblastoma: Long-term neurocognitive, functional, and physical outcomes Neuro Oncol 13 2011 536 545
25. Y. Koksal, H. Toy, and E. Unal et al. Pilocytic astrocytoma developing at the site of a previously treated medulloblastoma in a child Childs Nerv Syst 24 2008 289 292 (Pubitemid 351234067)
26. J.F. Fowler The linear-quadratic formula and progress in fractionated radiotherapy Br J Radiol 62 1989 679 694 (Pubitemid 19194494)
27. C. Carrie, J. Grill, and D. Figarella-Branger et al. Online quality control, hyperfractionated radiotherapy alone and reduced boost volume for standard risk medulloblastoma: Long-term results of MSFOP 98 J Clin Oncol 27 2009 1879 1883
28. T. Gupta, R. Jalali, and S. Goswami et al. Early clinical outcomes demonstrate preserved cognitive function in children with average-risk medulloblastoma when treated with hyperfractionated radiation therapy Int J Radiat Oncol Biol Phys 83 2012 1534 1540
29. V. Kieffer-Renaux, D. Viguier, and M.A. Raquin et al. Therapeutic schedules influence the pattern of intellectual decline after irradiation of posterior fossa tumors Pediatr Blood Cancer 45 2005 814 819 (Pubitemid 41416492)
30. B. Lannering, S. Rutkowski, and F. Doz et al. Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: Results from the randomized multicenter HIT-SIOP PNET 4 trial J Clin Oncol 30 2012 3187 3193
31. L. Embry, R.D. Annett, and A. Kunin-Batson et al. Implementation of multi-site neurocognitive assessments within a pediatric cooperative group: Can it be done? Pediatr Blood Cancer 59 2012 536 539
32. K.S. Bull, H.A. Spoudeas, and G. Yadegarfar et al. Reduction of health status 7 years after addition of chemotherapy to craniospinal irradiation for medulloblastoma: A follow-up study in PNET 3 trial survivors - on behalf of the CCLG (formerly UKCCSG) J Clin Oncol 25 2007 4239 4245 (Pubitemid 47548564)
33. G.A. Gioia, P.K. Isquith, and S.C. Guy et al. Behavior Rating Inventory of Executive Function 2000 Psychological Assessment Resources Lutz, FL
34. D. Feeny, W. Furlong, and R.D. Barr et al. A comprehensive multiattribute system for classifying the health status of survivors of childhood cancer J Clin Oncol 10 1992 923 928
35. R. Goodman The strengths and difficulties questionnaire: A research note J Child Psychol Psychiatr Allied Disciplines 38 1997 581 586 (Pubitemid 27341892)
36. J.W. Varni, M. Seid, and C.A. Rode The PedsQL: Measurement model for the pediatric quality of life inventory Med Care 37 1999 126 139
37. N.K. Aaronson, S. Ahmedzai, and B. Bergman et al. The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology J Natl Cancer Inst 85 1993 365 376 (Pubitemid 23073154)
38. T.E. Merchant, S.R. Rose, and C. Bosley et al. Growth hormone secretion after conformal radiation therapy in pediatric patients with localized brain tumors J Clin Oncol 29 2011 4776 4780
39. J.V. Freeman, T.J. Cole, and S. Chinn et al. Cross-sectional stature and weight reference curves for the UK 1990 Arch Dis Childhood 73 1995 17 24
40. A. Glaser, C. Kennedy, and J. Punt et al. Standardized quantitative assessment of brain tumor survivors treated within clinical trials in childhood Int J Cancer 1999 77 82
41. D.G. Altman, D. Machin, and T.N. Bryant et al. Statistics with Confidence 2nd ed 2002 BMJ Books London
42. C.W. Karlson, and M.A. Rapoff Attrition in randomized controlled trials for pediatric chronic conditions J Pediatr Psychol 34 2009 782 793
43. M.P. Chevignard, C. Soo, and J. Galvin et al. Ecological assessment of cognitive functions in children with acquired brain injury: A systematic review Brain Inj 26 2012 1033 1057
44. R.A. Howarth, J.M. Ashford, and T.E. Merchant et al. The utility of parent report in the assessment of working memory among childhood brain tumor survivors J Int Neuropsychol Soc 19 2013 380 389
45. V.A. Anderson, P. Anderson, and E. Northam et al. Relationships between cognitive and behavioral measures of executive function in children with brain disease Child Neuropsychol 8 2002 231 240 (Pubitemid 36577924)
46. G.A. Gioia, and P.K. Isquith Ecological assessment of executive function in traumatic brain injury Dev Neuropsychol 25 2004 135 158 (Pubitemid 38294394)
47. K. Wechsler-Jentzsch, H. Huepfel, and W. Schmidt et al. Failure of hyperfractionated radiotherapy to reduce bone growth arrest in rats Int J Radiat Oncol Biol Phys 26 1993 427 431 (Pubitemid 23182337)
48. S.M. Shalet, B. Gibson, and R. Swindell et al. Effect of spinal irradiation on growth Arch Dis Childhood 62 1987 461 464 (Pubitemid 17070000)
49. J.C. Probert, and B.R. Parker The effects of radiation therapy on bone growth Radiology 114 1975 155 162
50. W. Xu, A. Janss, and T. Moshang Adult height and adult sitting height in childhood medulloblastoma survivors J Clin Endocrinol Metab 88 2003 4677 4681 (Pubitemid 37357511)