Multi-Institution Prospective Trial of Reduced-Dose Craniospinal Irradiation (23.4 Gy) Followed by Conformal Posterior Fossa (36 Gy) and Primary Site Irradiation (55.8 Gy) and Dose-Intensive Chemotherapy for Average-Risk Medulloblastoma

International Journal of Radiation Oncology Biology Physics

Volumn 70, Issue 3, 2008, Pages 782-787

  Merchant, Thomas E ^a   Kun, Larry E ^a   Krasin, Matthew J ^a   Wallace, Dana ^a   Chintagumpala, Murali M ^b   Woo, Shiao Y ^c   Ashley, David M ^d   Sexton, Maree ^e   Kellie, Stewart J ^f   Ahern, Verity ^g   Gajjar, Amar ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b TEXAS CHILDREN S CANCER CENTER   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d ROYAL CHILDREN'S HOSPITAL   (Australia)

^e PETER MACCALLUM CANCER CENTRE   (Australia)

^f CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^g WESTMEAD HOSPITAL   (Australia)

Author keywords

Central nervous system neoplasm; Chemotherapy; Conformal radiotherapy; Pediatrics; Radiotherapy

Indexed keywords

CHEMOTHERAPY; DOSIMETRY; MEDICAL PROBLEMS; NEUROLOGY; PEDIATRICS; TUMORS;

CENTRAL NERVOUS SYSTEM NEOPLASM; CONFORMAL RADIOTHERAPY; MEDULLOBLASTOMA; NEUROCOGNITIVE SEQUELAE;

RADIOTHERAPY;

CISPLATIN; CYCLOPHOSPHAMIDE; VINCRISTINE;

ADOLESCENT; ADULT; ANALYTICAL ERROR; ARTICLE; BRAIN; BRAIN STEM; CANCER COMBINATION CHEMOTHERAPY; CANCER INCIDENCE; CANCER RADIOTHERAPY; CANCER RISK; CANCER SURGERY; CANCER THERAPY; CHILD; CHRONOTHERAPY; CLINICAL TRIAL; COCHLEA; COGNITION; COMPARATIVE STUDY; COMPUTER ASSISTED RADIOTHERAPY; DISEASE CONTROL; DISEASE FREE SURVIVAL; DRUG MEGADOSE; FEMALE; FOLLOW UP; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HYPOTHALAMUS; MAJOR CLINICAL STUDY; MALE; MEDULLOBLASTOMA; MULTICENTER STUDY; MULTIMODALITY CANCER THERAPY; MULTIPLE CYCLE TREATMENT; POSTERIOR FOSSA; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; SKULL; SPINE; STATISTICAL SIGNIFICANCE; TEMPORAL LOBE; TREATMENT FAILURE;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; CISPLATIN; COGNITION DISORDERS; COMBINED MODALITY THERAPY; CYCLOPHOSPHAMIDE; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; INFRATENTORIAL NEOPLASMS; MALE; MEDULLOBLASTOMA; PROSPECTIVE STUDIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; TUMOR BURDEN; VINCRISTINE;

EID: 38849130053     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.07.2342     Document Type: Article

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