Imbalanced lipid homeostasis in the conditional Dicer1 knockout mouse epididymis causes instability of the sperm membrane

FASEB Journal

Volumn 29, Issue 2, 2015, Pages 433-442

  Björkgren, Ida ^a,b   Gylling, Helena ^c,d   Turunen, Heikki ^a   Huhtaniemi, Ilpo ^e   Strauss, Leena ^a   Poutanen, Matti ^a,f   Sipilä, Petra ^d,g  

^a UNIVERSITY OF TURKU   (Finland)

^b Turku Doctoral Programme of Biomedical Sciences   (Finland)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF GOTHENBURG   (Sweden)

^g UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DOCOSAPENTAENOIC ACID; FOLLITROPIN; GAMMA LINOLENIC ACID; ICOSATETRAENOIC ACID; LONG CHAIN POLYUNSATURATED FATTY ACID; LUTEINIZING HORMONE; MEMBRANE LIPID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; SPHINGOMYELIN; STEARIDONIC ACID; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID; VERY LONG CHAIN FATTY ACID LIKE 2; DEAD BOX PROTEIN; DICER1 PROTEIN, MOUSE; RIBONUCLEASE III; UNSATURATED FATTY ACID;

ACROSOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DICER1 GENE; EPIDIDYMIS; EPIDIDYMIS TAIL; FATTY ACID SYNTHESIS; FEMALE; FERTILIZATION IN VITRO; FOLLITROPIN BLOOD LEVEL; GENE; GENE EXPRESSION; HORMONE DETERMINATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KNOCKOUT MOUSE; LIPID COMPOSITION; LIPID HOMEOSTASIS; LIPOGENESIS; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE FERTILITY; MEMBRANE STABILIZATION; MOUSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA ISOLATION; SEPTUM PELLUCIDUM; SPERMATOGENESIS; SPERMATOZOON; SPERMATOZOON CAPACITATION; SPERMATOZOON MATURATION; SPERMATOZOON MEMBRANE; SPERMATOZOON MOTILITY; TESTIS; UPREGULATION; ACROSOME REACTION; ANIMAL; GENETICS; HOMEOSTASIS; LIPID METABOLISM; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; ZONA PELLUCIDA;

MUS;

ACROSOME REACTION; ANIMALS; CHOLESTEROL; DEAD-BOX RNA HELICASES; EPIDIDYMIS; FATTY ACIDS, UNSATURATED; HOMEOSTASIS; LIPID METABOLISM; MALE; MEMBRANE LIPIDS; MICE; MICE, KNOCKOUT; RIBONUCLEASE III; RNA INTERFERENCE; SPERM CAPACITATION; SPERM MATURATION; SPERM MOTILITY; SPERMATOGENESIS; SPERMATOZOA; SPHINGOMYELINS; TESTIS; ZONA PELLUCIDA;

EID: 84937398230     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-259382     Document Type: Article

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