Sphingomyelin modulates capacitation of human sperm in vitro

Biology of Reproduction

Volumn 63, Issue 4, 2000, Pages 1129-1134

  Cross, N L ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Acrosome reaction; Fertilization; Sperm capacitation

Indexed keywords

CERAMIDE; CHOLESTEROL; DESMOSTEROL; PROGESTERONE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE DERIVATIVE; STEROL;

ACROSOME REACTION; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; EXOCYTOSIS; FERTILIZATION; HUMAN; MALE; PRIORITY JOURNAL; SPERMATOZOON CAPACITATION; SPERMATOZOON MATURATION;

MAMMALIA;

EID: 0033806720     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod63.4.1129     Document Type: Article

References (58)

1. Mammalian fertilization
2. Observations on the penetration of sperm into the mammalian egg
3. The fertilizing capacity of spermatozoa deposited into the fallopian tubes
4. Role of cholesterol in sperm capacitation
5. Sperm membrane potential: Hyperpolarization during capacitation regulates zona pellucida-dependent acrosomal secretion
6. Cyclic nucleotides and mammalian sperm capacitation
7. Role of membrane phosphotyrosine proteins in human spermatozoal function
8. Cyclic AMP-dependent phosphorylation of epididymal mouse sperm proteins during capacitation in vitro - Identification of an M(r) 95 000 phosphotyrosine-containing protein
9. Calyculin A, protein phosphatase inhibitor, enhances capacitation of human sperm
10. Effects of modulators of protein kinase C on human sperm capacitation
11. Capacitation of mouse spermatozoa. II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway
12. Cyclic adenosine 3',5' monophosphate-dependent regulation of protein tyrosine phosphorylation in relation to human sperm capacitation and motility
13. Capacitation of bovine sperm by heparin: Inhibitory effect of glucose and role of intracellular pH
14. Intracellular pH of bovine sperm increases during capacitation
15. --dependent and arylaminobenzoate-dependent regulatory mechanisms and characterization of their roles in sperm capacitation
16. Control of human sperm intracellular pH by cholesterol and its relationship to the response of the acrosome to progesterone
17. Sperm surface components involved in the control of the acrosome reaction
18. 2+-ATPase
19. Intracellular calcium accumulation and responsiveness to progesterone in capacitating human spermatozoa
20. Unesterified cholesterol content of human sperm regulates the response of the acrosome to the agonist, progesterone
21. Regulation of human sperm capacitation by a cholesterol efflux-stimulated signal transduction pathway leading to protein kinase A mediated up-regulation of protein tyrosine phosphorylation
22. Studies on the mechanism of capacitation. II. Evidence for lipid transfer between plasma membrane of rat sperm and serum albumin during capacitation in vitro
23. Purification and characterization of a human follicular fluid lipid transfer protein that stimulates human sperm capacitation
24. Effect of cholesterol and other sterols on human sperm acrosomal responsiveness
25. Changes in the lipid content of boar sperm membranes during epididymal maturation
26. Phospholipids of rabbit and bull sperm membranes: Structural order parameter and steady-state fluorescence anisotropy of membranes and membrane leaflets
27. Lipids of plasma membrane and outer acrosomal membranes from bovine spermatozoa
28. Effects of sphingomyelin degradation on cell cholesterol oxidizability and steady-state distribution between the cell surface and the cell interior
29. Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts
30. Neutral sphingomyelinase increases the binding, internalization, and degradation of low density lipoproteins and synthesis of cholesteryl ester in cultured human fibroblasts
31. Degradation of plasma membrane phosphatidylcholine appears not to affect the cellular cholesterol distribution
32. Intracellular trafficking of cholesterol monitored with a cyclodextrin
33. Sphingolipid-cholesterol rafts in membrane trafficking and signaling
34. Human sperm acrosome reaction-initiating activity associated with the human cumulus oophorus and mural granulosa cells
35. Multiple effects of seminal plasma on the acrosome reaction of human sperm
36. Induction of the acrosome reaction in human spermatozoa by a fraction of human follicular fluid
37. A rapid method of total lipid extraction and purification
38. Thin-layer chromatography of lipids
39. A rapid sensitive method for determining phospholipid phosphorus involving digestion with magnesium nitrate
40. Effect of methyl-β-cyclodextrin on the acrosomal responsiveness of human sperm
41. Ceramide and sphingomyelinases in the regulation of stress responses
42. Ceramide stimulates a cytosolic protein phosphatase
43. Characterization of a ceramide-activated protein kinase: Stimulation by tumor necrosis factor alpha
44. Ceramide activates heterotrimeric protein phosphatase 2A
45. Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells
46. Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway
47. Sphingomyelinase and ceramide suppress insulin-induced tyrosine phosphorylation of the insulin receptor substrate-1
48. Role for ceramide in cell cycle arrest
49. Biophysics of ceramide signaling: Interaction with proteins and phase transition of membranes
50. Ceramides modulate protein kinase C activity and perturb the structure of phosphatidylcholine/phosphatidylserine bilayers
51. Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation
52. Inhibition of fertilizing capacity in mammalian spermatozoa by natural and synthetic vesicles
53. Sphingomyelin-cholesterol interactions in biological and model membranes
54. 2, an effector of capacitation induces a rapid and reversible change in the lipid architecture of boar sperm plasma membranes
55. A neutral sphingomyelinase in spermatozoal plasma membranes
56. Diacyl, alkenyl, and alkyl ether phospholipids in ejaculated, in utero-, and in vitro-incubated porcine spermatozoa
57. Phospholipids in guinea pig spermatozoa before and after capacitation in vitro
58. Phospholipid composition of isolated guinea pig sperm outer acrosomal membrane and plasma membrane during capacitation in vitro