Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes

Mitochondrion

Volumn 18, Issue 1, 2014, Pages 41-48

  Choi, Joungil ^a,b   Ravipati, Avinash ^a,b   Nimmagadda, Vamshi ^a,b   Schubert, Manfred ^c   Castellani, Rudolph J ^d   Russell, James W ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

Alzheimer disease; Diabetes; Mitochondria; PGC 1 ; PINK1

Indexed keywords

ACETYLCYSTEINE; FAT DROPLET; HYDROGEN PEROXIDE; LONG CHAIN 3 HYDROXYACYL COENZYME A DEHYDROGENASE; MITOCHONDRIAL ENZYME; MITOCHONDRIAL TRIFUNCTIONAL ENZYME SUBUNIT ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PINK1 PROTEIN; UNCLASSIFIED DRUG; FATTY ACID; PPARGC1A PROTEIN, HUMAN; PPARGC1A PROTEIN, MOUSE; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; TRANSCRIPTION FACTOR;

ADULT; AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; FATTY ACID OXIDATION; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY;

ALZHEIMER DISEASE; ANIMALS; DIABETES MELLITUS; FATTY ACIDS; GENE EXPRESSION PROFILING; HUMANS; MICE; MITOCHONDRIA; OXIDATION-REDUCTION; PROTEIN KINASES; TRANSCRIPTION FACTORS;

EID: 84937346336     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2014.09.005     Document Type: Article

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